490 results about "Patient compliance" patented technology

The invention relates to a digital chronic disease intelligent management platform based on an AI model and multi-dimensional data fusion, clinical diagnosis and treatment data, wearable equipment monitoring data, medication record data and environment monitoring data are acquired through a data acquisition module, and after standardized preprocessing is performed through a data fusion processing module, deep analysis is performed through an AI analysis module, and the data fusion processing module performs data fusion processing; in combination with medical knowledge of the knowledge base module, the intelligent decision-making module generates a personalized management scheme, and the personalized management scheme is implemented through the intervention execution module and the intelligent interaction module. Multi-dimensional health data are processed through an AI large model, a complex mode and an association relationship are automatically learned, and accurate disease prediction and risk assessment are realized; the pertinence of the scheme and the compliance of a patient are greatly improved; and real-time interaction and personalized guidance are provided, the participation degree and the self-management ability of the patient are effectively enhanced, and a benign health management cycle is formed.

The invention discloses a rehabilitation exercise system and method based on intelligent interaction, and relates to the technical field of medical rehabilitation, intelligent management of basic information, medical history information, treatment information and medication information of patients is realized through a patient information management module; personalized exercise plans and real-time action guidance are provided for the patient through the rehabilitation exercise module; dynamically evaluating the rehabilitation state of the patient through a rehabilitation evaluation module; a friend communication platform is established through the community interaction module, and science popularization education is provided; and real-time monitoring and early warning of the doctor on the rehabilitation process of the patient are realized through the doctor supervision module. The artificial intelligence technology is adopted, the rehabilitation actions of the patient are monitored and corrected in real time through the camera, the rehabilitation state of the patient is evaluated through the electronic scale and the intelligent scoring system, the exercise plan is dynamically adjusted according to the rehabilitation condition of the patient, the rehabilitation exercise accuracy and the patient compliance are effectively improved, and the rehabilitation effect of the patient is improved. And the intelligent and electronic management of the whole rehabilitation exercise process can be realized.

The invention provides a dynamic adjustment method based on a depression mind-correcting treatment scheme, and relates to the technical field of medical care information, and the method comprises the steps: collecting multi-dimensional information of a patient, and collecting life behavior risk data, psychological scale data and cognitive function evaluation data; comprehensively evaluating the depression level of the patient; determining the priority of a treatment therapy module according to the multi-dimensional information of the patient; generating an initial treatment scheme; calculating a daily task comprehensive weight value, and dynamically adjusting the training content of the next day; and evaluating the state of the patient in stages, recalculating the priority of each therapy module, and optimizing the therapeutic scheme. Through multi-dimensional data fusion evaluation and intelligent algorithm dynamic adjustment, a complete closed-loop feedback optimization system is constructed, precision and individuation of a depression treatment scheme are achieved, the treatment effect and patient compliance are effectively improved, the recurrence risk is reduced, and a more scientific and effective treatment scheme is provided for depression patients.

The invention provides an internal medicine multi-parameter real-time remote monitoring system based on the Internet of Things, and belongs to the technical field of remote monitoring, the internal medicine multi-parameter real-time remote monitoring system comprises an integrated data acquisition terminal, a heterogeneous network communication module, an intelligent remote analysis server and a user interaction terminal, and the integrated data acquisition terminal adopts a medical grade flexible wearable design. According to the internal medicine multi-parameter real-time remote monitoring system based on the Internet of Things provided by the invention, the efficiency of remote monitoring of internal medicine diseases is remarkably improved through multi-dimensional technical innovation. On the data processing level, efficient fusion and stable transmission of multi-source data are achieved, and the real-time performance and integrity of monitoring data are guaranteed; in an analysis level, a specialized deep neural network model is combined with environmental factors, so that the accuracy of health state assessment and risk prediction is greatly improved; according to the application level, through a personalized rehabilitation scheme, intelligent early warning and remote equipment management, the medical service process is optimized, and patient compliance and medical cooperation efficiency are improved.

The invention relates to the technical field of medical information systems, in particular to a tumor follow-up visit management method and system based on multi-source data fusion, and the method comprises the steps: obtaining patient data from an electronic medical record, an examination report and a follow-up visit record; based on the patient data, adopting a natural language processing technology to extract structured follow-up visit knowledge; according to follow-up visit knowledge, constructing a'patient-main diagnosis doctor-tumor type 'triple (P, C, c); based on the triple (P, C, c), mapping with a hospital disease score library, a doctor score library, a hospital grade corresponding database and a doctor individualized database by using a rule engine to obtain a patient score P and a doctor score Rc; a personalized follow-up scheme and a patient compliance evaluation result are generated, and comprehensive and accurate patient information is provided for doctors through multi-source data fusion. Therefore, the accuracy of follow-up decision making is improved, the time for doctors to collect information is greatly shortened, and the working efficiency is improved.

The invention relates to the technical field of reinforcement learning, and discloses a chronic disease intervention scheme generation method and system based on reinforcement learning and multi-modal data, and the method comprises the steps: obtaining the multi-modal data of a patient, the multi-modal data at least comprising electronic medical record data, voice data, image data, text data and physiological time sequence data; performing feature extraction on the multi-modal data to obtain a multi-modal feature vector; on the basis of the multi-modal feature vectors, health state vectors are constructed, and the health state vectors at least comprise a physiological risk score, a treatment compliance score and a lifestyle health degree score; designing a reward function according to the dynamic change of the health state vector; optimizing the strategy network in a predefined intervention action space according to the reward function by utilizing a reinforcement learning algorithm so as to output an optimal intervention action; and converting the optimal intervention action into personalized natural language interaction content through a generative AI model. According to the invention, the efficiency, precision and patient compliance of chronic disease management can be significantly improved.

The invention discloses a compound composition for improving sleep disorders, which is characterized by comprising the following components: an inhibitory neurotransmitter component, melatonin and a nano-lipid carrier, the nano-lipid carrier comprises phospholipid and cholesterol, the weight ratio of phospholipid to cholesterol is (1-6): 1, the weight ratio of phospholipid to cholesterol is (1-6): 1, and the weight ratio of melatonin to cholesterol is (1-6): 1. The inhibitory neurotransmitter component is wrapped in the nano-lipid carrier to form lipid nanoparticles, and the weight ratio of the inhibitory neurotransmitter component to the nano-lipid carrier is 1: (1-15). The compound composition can be prepared into a compound oral mucosa preparation, can be rapidly disintegrated when encountering saliva in the oral cavity, is good in patient compliance and small in side effect, all the components play a synergistic effect from different mechanisms through multiple target points, and the compound oral mucosa preparation can improve the sleep quality, prolong the sleep time and shorten the sleep latency; and patients with sleep disorders are helped to improve insomnia from the pathologic root.

The invention provides an inhalable tanshinone IIA lipid nanocrystal as well as a preparation method and application thereof, and the inhalable tanshinone IIA lipid nanocrystal is mainly formed by entrapping tanshinone IIA by using dipalmitoyl phosphatidylcholine DPPC and dipalmitoyl phosphatidyl ethanolamine DPPE as mixed phospholipids in the presence of a stabilizer. Compared with the prior art, the inhalable tanshinone IIA lipid nanocrystal disclosed by the invention has the advantages that by improving the physicochemical property and drug release behavior of TA, the lung retention volume of TA after aerosol inhalation is obviously increased, the retention time of TA in the lung is prolonged, and the risk of toxic and side effects caused by whole-body escape of drugs is reduced; the treatment effect on idiopathic pulmonary fibrosis is improved, and the compliance of a patient is improved.

The invention relates to an intelligent decision-making system for nutrition metabolism collaborative management of elderly chronic disease patients, in particular to the field of nutrition metabolism collaborative management of elderly chronic disease, which is characterized in that drug molecule characteristics and nutrient metabolism paths are dynamically integrated through a multi-modal knowledge graph, and a cross-domain associated three-dimensional knowledge network is constructed; based on a reinforcement learning real-time optimization rule confidence threshold value, the early warning sensitivity is adaptively adjusted according to the degree that the metabolic index of the patient deviates from the safety interval; the streaming conflict detection engine accurately identifies the potential risk of asynchronously input medication and diet data, and triggers graded early warning through space-time alignment and sub-graph matching; the closed-loop evolution mechanism fuses patient compliance feedback and blood potassium change trend, drives the taboo rule base to continuously and autonomously evolve under the constraint of renal function layering, and realizes personalized risk prevention and control and metabolic state collaborative optimization.

The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

The invention provides a hypertension VR intervention method based on dynamic biofeedback and individualized modeling, and provides a hypertension VR intervention system based on dynamic biofeedback and individualized modeling. The method comprises the following steps: performing state analysis on dynamic biological feedback indexes of a hypertensive patient, namely a predicted pressure index (SPI) and an exercise intensity index (EII), deciding a hypertension VR intervention decision matched with the state of the dynamic biological feedback indexes, activating a VR scene of the corresponding decision in a system, and actively enabling the hypertensive patient to perform adaptive intervention training through VR equipment. Therefore, dynamic biological feedback intervention is realized by utilizing an intelligent decision training mode of the intelligent model. According to the method, training mode recommendation can be accurately carried out according to the patient state, state reward can be carried out according to the blood pressure change amplitude and the patient compliance score, so that the patient training mode is optimized, intelligent training is achieved, and the method has high guiding significance.

The embodiments of the present invention relate to a stable liquid vigabatrin pharmaceutical compositions in the liquid form of a solution. Particularly, the stable vigabatrin liquid pharmaceutical composition is manufactured as a ready-to-use industrialized premixture that does not require reconstitution or dilution prior to administration to a patient. The vigabatrin liquid pharmaceutical composition is stable six months or longer at room temperature and has levels of total impurities and Vigabatrin-related compound A that are both not more than 0.04% at, or prior to, six months. In some embodiments, the composition has improved stability and patient compliance. In some embodiments, the compositions may be advantageous for the patients having swallowing difficulties or when the patients are unable to take solid oral dosage forms. In some embodiments, the composition improves compliance with ketogenic diet.

The invention discloses an intelligent drug delivery pain management bracelet, and relates to the fields of wearable equipment, transdermal drug delivery and biological signal processing. The bracelet is integrated with a multi-mode biosensor which comprises a temperature sensor, a pressure sensor, a heart rate sensor, a blood oxygen sensor and a skin electric response sensor, and physiological data related to pain can be collected in real time. Through an embedded microcontroller and a machine learning algorithm, a pain intensity evaluation model is constructed, and real-time evaluation of the pain state of a patient is realized. Based on the pain intensity and the physiological state of a patient, a drug release strategy is dynamically adjusted through an intelligent algorithm, and drugs are released painlessly and accurately through a micro-needle transdermal drug delivery technology, so that the patient obtains the optimal treatment effect. And the functions of data storage, historical analysis and remote doctor monitoring can be expanded. The hand ring is convenient to operate, comfortable to use and suitable for various pain management scenes such as chronic pain and postoperative pain, and the personalized level of pain treatment and patient compliance are remarkably improved.

The invention discloses a capsule medicament for endoscopic treatment of ulcerative colitis and a preparation method thereof, and belongs to the technical field of biological medicine, the capsule medicament is composed of a capsule matrix and a drug matrix; by adopting a dual control mechanism of an enteric layer coating and a pH response layer coating, accurate release of a medicine at a colon diseased region is ensured, medicine waste of the stomach and the small intestine is reduced, the medicine concentration at a focus is improved, mesalazine or budesonide is combined with the composite composition for treatment, inflammatory response is rapidly inhibited, acute symptoms are controlled, and the curative effect is good. A multi-mechanism synergistic treatment mode is adopted, the anti-inflammatory and repairing effects are enhanced, the clinical remission rate and the mucous membrane healing rate are remarkably improved, the pH response layer is dissolved in a colon alkaline environment, and the MMP-9 peptide cross-linking agent is subjected to enzymolysis at an inflammation part, so that the medicine is continuously released at a focus, the administration frequency is reduced, the compliance of a patient is improved, and the curative effect is good. In addition, the spherical gel particles in the medicament can prevent the medicament from being disintegrated too early in the intestinal tract, and the long-acting effect can be maintained.

The invention relates to the technical field of medical information, in particular to an endocrine patient long-term medication tracking management method and system, and the method comprises the following steps: extracting multiple pieces of key information in a prescription based on the electronic prescription information of a patient, recognizing the taking time and dosage information of multiple medicines, and sending medication reminding information to the patient, by monitoring the opening and closing state of the medicine box, the medicine taking time and quantity are recorded, and reminding and medicine taking monitoring information is generated. According to the method, the opening and closing state of the medicine box is monitored in real time, the taking time and quantity of medicine are recorded, the transparency of medicine treatment and the compliance of a patient are improved, physiological parameters of the patient are collected regularly, time sequence analysis and doctor feedback are matched, the change trend and periodic fluctuation of the illness state of the patient are accurately recognized, and the patient compliance is improved. By analyzing drug use logs of patients and doctors, effects of various drugs are identified, side effects are detected, drug doses and types are helped to be adjusted in time, the risk of adverse drug reactions is effectively reduced, and the treatment effect is improved.

The invention relates to a patient post-hospital follow-up visit system and a follow-up visit method, and relates to the technical field of medical treatment, and the system comprises a risk index module which is used for determining a risk index after a patient is discharged from a hospital; the follow-up visit frequency module is used for determining personalized follow-up visit frequency obtained by dynamically adjusting the risk index of the patient; the priority determination module is used for determining the task priority of the patient follow-up visit task; an integrity evaluation module for determining a data integrity indicator for evaluating the multi-modal data of the patient; the health early warning module is used for determining an early warning value for evaluating the health state of the patient according to the risk index of the patient, the personalized follow-up visit frequency, the task priority and the four-dimensional parameter set of the data integrity index; and the comprehensive evaluation module is used for determining a comprehensive evaluation index of the follow-up visit effect according to a ternary evaluation system of the early warning score, the data integrity index and the patient compliance parameter in combination with a configurable weight coefficient. The system can improve the follow-up visit effect of the patient.

The invention provides a cyclodextrin-based nano anti-tumor medicine preparation as well as a preparation method and application thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: preparing a graphene quantum dot deposition gold nanocage modified by a silane coupling agent, carrying out a Schiff base reaction on the graphene quantum dot deposition gold nanocage and aldehyde substituted-beta-cyclodextrin to prepare a composite carrier, and coating a targeted peptide-drug compound through the reaction, thereby preparing the cyclodextrin-based nano anti-tumor drug preparation. According to the cyclodextrin-based nano anti-tumor medicine preparation prepared by the invention, the anti-tumor medicine effect is obviously improved, meanwhile, the medicine resistance of the medicine can be reversed, the damage to normal tissues is reduced, the use amount of the medicine is reduced, the side effect after the medicine is used is reduced, the compliance of a patient is improved, and meanwhile, the stability and biocompatibility of the medicine can be improved; wide application prospects are realized.

Provided are a sustained-release microsphere for polypeptide drugs, a pharmaceutical formulation thereof, a method for preparing same, and use thereof. The method comprises the following steps: forming an inner aqueous phase; forming an oil phase; forming an outer aqueous phase; and dispersing the inner aqueous phase into the oil phase to give a primary emulsion, then re-dispersing the primary emulsion into the outer aqueous phase to give a pre-secondary emulsion, emulsifying the pre- secondary emulsion to form a secondary emulsion, and finally curing the secondary emulsion to give the sustained-release microsphere. The method features ease to operate, and the obtained sustained-release microsphere possesses ideal drug release behaviors (low early burst release, and stable mid- and later-stage releases) and safety and potency in reducing blood glucose, and is thus suitable for stable, long-term use with good patient compliance.

The invention relates to the technical field of pharmaceutical preparations, and provides an oral solid preparation for treating gout and a preparation method thereof. The preparation method comprises the following steps: sieving a filling agent, a disintegrating agent, an adhesive and dotenorad to obtain a sieved material; and mixing the sieved material and a lubricant, and tabletting to obtain the oral solid preparation for treating gout, the filling agent is lactose, mannitol and microcrystalline cellulose. By optimizing the prescription and the preparation process, the dissolution rate and bioavailability of the medicine are improved, so that the curative effect is improved; by selecting proper auxiliary materials and preparation types, the stimulation to gastrointestinal tracts is reduced, and the tolerance of patients is improved; the oral solid preparation is convenient to take, accurate in dosage, high in patient compliance and beneficial to long-term treatment; moreover, the preparation method provided by the invention is simple to operate, easy for industrial production and relatively low in cost.

The utility model discloses a rehabilitation training device for nursing chronic obstructive pulmonary disease, a pedaling device comprises a mounting frame and a linkage assembly, and the mounting frame is arranged on the other side of a support frame; the linkage assembly is rotatably arranged in the mounting frame; the breathing device comprises a breathing box, a breathing assembly, a hose and a mask, and the breathing box is arranged on one side of the top of the mounting frame; the breathing assembly is arranged in the breathing box, and the breathing assembly is connected with the linkage assembly; one end of the hose is connected with the breathing assembly; the mask is connected with the other end of the hose; the control system comprises a microprocessor, and the microprocessor is arranged in the breathing box and connected with the breathing assembly. Therefore, the device combines pedaling and breathing training, strengthens lower limb strength and improves the breathing function, the linkage assembly ensures synchronization of the pedaling and breathing training, the training effect is improved, the built-in control system monitors breathing in real time, the training intensity is automatically adjusted, safety and comfort are guaranteed, and the training effectiveness and patient compliance are improved.

The present invention relates to the technical field of anti-aging compositions and particularly to an anti-aging composition and use thereof, and an anti-aging capsule and use thereof. The present invention provides an anti-aging composition comprising the following components: 20-2000 parts by mass of calcium α-ketoglutarate, 20-100 parts by mass of quercetin, 20-2000 parts by mass of trans-resveratrol, 20-100 parts by mass of calendulin, and 0.02-1.8 parts by mass of spermidine. The composition of the present invention has a multi-target synergistic effect on 12 major causes of aging and can safely and effectively reverse aging, enhance the physiological function, reduce the risk of chronic diseases, and improve the quality of life. The components of the composition are safe, and are carefully selected natural food ingredients; therefore, the composition is safe and reliable, and has no side effects with long-term use. The composition is prepared in an oral dosage form, so that the composition is convenient to administer, which improves patient compliance; moreover, the mode of application of the composition can be expanded.

The invention relates to the technical field of chronic obstructive pulmonary disease rehabilitation medical equipment and services, discloses a chronic obstructive pulmonary disease multi-mode respiratory training system based on behavioral design science, and aims to solve the technical problems that an existing respiratory training product is poor in patient compliance, poor in user experience and lack of personalized behavior guidance. The system comprises a hardware equipment cluster and a software service platform, a multi-dimensional intervention architecture is constructed based on an FBM behavior model, and closed-loop services of respiratory training, drug management, health monitoring and rehabilitation support are realized through an motivation promotion module, a capability optimization module, a multi-sensory prompt module and a data interaction module. The system effectively stimulates the training enthusiasm of a patient, reduces the operation threshold, improves the training and medication compliance, improves the respiratory function and life quality of the patient, reduces the consumption of medical resources, and has remarkable clinical application value and social and economic benefits through deep fusion of behavioral design and a multi-modal rehabilitation technology.

The invention belongs to the technical field of gene engineering, and relates to an esophageal squamous cell carcinoma diagnostic kit based on a peripheral blood mononuclear cell methylation marker and application. The kit comprises a primer pair which is used for detecting the methylation of a cg05914150 site, a cg06769875 site, a cg07475126 site, a cg08433285 site, a cg10038907 site, a cg17968322 site, a cg19572487 site, a cg20184330 site, a cg22741248 site and a cg22823192 site. According to the detection kit provided by the invention, the type of a detected sample is peripheral blood, the sample is relatively easy to obtain and non-invasive, and the patient compliance is relatively good. Abnormal methylation changes mostly exist in the early progression process of tumors, early diagnosis of ESCC can be achieved through the methylation detection method provided by the invention, and the five-year survival rate of ESCC patients is effectively increased.

The invention belongs to the technical field of medicines, and particularly relates to a fenerenone orally disintegrating tablet and a preparation method thereof. The active component of the fenerenone orally disintegrating tablet is fenerenone, and the fenerenone orally disintegrating tablet comprises the following components in percentage by weight: 10-15% of fenerenone, 10-15% of magnesium stearate, 10-15% of magnesium stearate and the balance of 70-80% of a filler; 5.5-10% of a disintegrating agent; 1-4% of a flow aid; and 1-4% of a lubricant. The finerenone orally disintegrating tablet disclosed by the invention is suitable for being taken by diabetics, and has the advantages of high disintegration and dissolution speed, stable finished product quality, no need of being taken with water and strong patient compliance; in addition, the finerenone orally disintegrating tablet disclosed by the invention is simple in preparation process, low in cost and suitable for large-scale production.

The invention discloses an intelligent intestinal preparation scheme management method and system for a colonoscope patient, and relates to the technical field of data processing, and the method comprises the steps: collecting the basic information of the patient and the failure experience of intestinal preparation, extracting personalized features, and carrying out the optimization of an intestinal preparation scheme based on the personalized features, generating a plurality of groups of alternative schemes and selecting an optimal scheme to execute intestinal tract cleaning; the method comprises the following steps: receiving a feedback image, dynamically generating anomaly compensation by using a time sequence anomaly recognition model, performing optimization iteration on an optimal scheme in combination with compensation information, and establishing an optimal intestinal preparation scheme. The technical problems of poor cleaning effect, frequent adverse reaction and low patient compliance caused by lack of individuation and insufficient real-time dynamic adjustment capability of intestinal preparation in the prior art are solved, and the effects of improving the intestinal cleaning effect, reducing the adverse reaction and improving the patient compliance are realized through the design of an individualized intestinal preparation scheme. The compliance of the patient and the examination efficiency are improved.

The invention discloses a total nutrient formula food suitable for patients with nephropathy and a preparation method thereof. The formula food consists of the following components in percentage by mass: 2-3% of calcium caseinate; 12%-20% of solid starch sugar; 2%-4% of soybean oil, high oleic acid sunflower seed oil and medium chain triglyceride; 3%-5% of mineral substances; 3%-5% of vitamin; 3%-5% of a food additive; 2%-3% of fruit and vegetable powder; and the balance purified water. According to the nutritional requirements of kidney disease patients, protein and electrolyte levels are reasonably designed, the flavor of the product is adjusted, disease progression can be obviously delayed and dialysis time can be delayed when chronic kidney disease non-dialysis patients use the product on the basis of reasonable medication, and the product has excellent nutriology characteristics and patient compliance, and has good clinical application prospects. The nutritional requirements of patients can be met, and the disease progress is delayed.

The invention discloses a microneedle system for continuous blood glucose monitoring, which comprises a microneedle array, an electrode system, a circuit connection and signal acquisition unit and a fixing and packaging structure, the working electrode is used for penetrating into the skin and making contact with intertissue fluid to control the diffusion speed of glucose and prevent glucose oxidase from losing, the surface of the working electrode is wrapped with glucose oxidase cross-linked and fixed through glutaraldehyde, one end of the electrode system is inserted into the microneedle, and the other end of the electrode system is connected with the circuit connection and signal acquisition unit. The fixing and packaging structure is arranged on the outer side of the circuit connecting and signal collecting unit and used for wrapping the electronic device and fixing the microneedle system to the skin surface. According to the microneedle system for continuous blood glucose monitoring, rapid and accurate detection of in-vivo blood glucose level changes is achieved, and minimally invasive property and good patient compliance can be achieved while the detection sensitivity and accuracy are guaranteed.

The present invention discloses a fusion protein, a high-density lipoprotein containing the fusion protein, and a bionic nano-drug, as well as preparation and application thereof. The fusion protein comprises an alpha-helical amphipathic polypeptide and a neuron targeting peptide. The high-density lipoprotein containing the fusion protein is used as a bionic nano-carrier to achieve brain-targeted delivery of the drug through intravenous administration, which saves manpower, material resources and financial resources compared with in situ administration to the brain, and significantly improves patient compliance.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a tiopronin-containing composition as well as a preparation method and application thereof. The preparation method comprises the following steps: granulating by adopting isopropanol as a granulating solution, drying and tabletting to obtain a tablet core with extremely low water content, and meanwhile, dissolving a mixture of an amine alkyl methacrylate copolymer and hydroxypropylcellulose in isopropanol as an isolating layer solution to coat the tablet core, so that the stability of the tablet core is improved; and finally, calcium carbonate, cane sugar and the like are adopted for sugar coating, so that unpleasant odor is effectively covered, the compliance of a patient is improved, the preparation is suitable for large-scale production, the medicine taking convenience and the medicine administration safety of the patient are improved, and therefore, the preparation has a good practical application value.

The invention relates to a real-time image guiding system, and relates to the technical field of image guiding. The real-time image guiding system comprises image robots, the image robots comprise the first image robot and the second image robot, and the first image robot can dynamically adjust the posture and the position of the first image robot so that an imaging light beam emitted by the first image robot can be received by the second image robot; the second image robot can dynamically adjust the posture and the position of the second image robot, so that an imaging light beam emitted by the second image robot can be received by the first image robot, and the imaging light beam emitted by the first image robot and the imaging light beam emitted by the second image robot intersect at a specified position to obtain a three-dimensional real-time image. According to the real-time image guiding system, the problem that new errors are introduced due to the fact that a patient needs to be positioned for multiple times can be avoided; and the first image robot and the second image robot can dynamically adjust the postures and the positions, so that the treatment efficiency and the patient compliance can be improved.