74 results about "Postoperative pain" patented technology

The invention relates to the technical field of intelligent medical treatment, in particular to an abdominal postoperative pain intelligent medical management system based on a JBI mode. The system comprises a platform application layer which is used for providing a user interface and an interaction mode, and medical staff and patients can access and use various services provided by a platform service layer; the platform service layer is used for monitoring and analyzing the pain level of a patient in real time, giving an alarm when the pain level is abnormal, and formulating and adjusting an analgesia strategy according to the pain level; and the evaluation feedback unit is used for formulating an evaluation index for the result of the platform service layer and optimizing the service according to the result of the index. The system not only records the pain score and accompanying symptoms of the patient, but also performs customized pain assessment according to different types of patients, so that the working efficiency of medical personnel is improved, the treatment compliance and satisfaction of the patient are enhanced, and finally the overall pain management level and the life quality of the patient are improved.

The invention relates to the technical field of medical instruments, in particular to a flexible ureteroscope used in cooperation with a diameter-variable ureteroscope sheath, which comprises a ureteroscope sheath body and a flexible ureteroscope body, the ureteroscope sheath body comprises a deformation section and a support section, the deformation section has a first form and a second form, and the flexible ureteroscope body comprises a handle section and a ureteroscope tube section. The endoscope tube section comprises a first tube body part and a second tube body part, a fixing groove is formed in the first tube body part, and the outer diameter of the deformation section in the first form is smaller than or equal to the outer diameter of the first tube body part; the inner diameter of the deformation section in the second form is greater than the outer diameter of the first pipe body part; a first liquid injection channel is further arranged in the endoscope tube section, and a first liquid outlet hole is formed in the fixing groove. Compared with the prior art, in the operation of expanding the human body ureterostenosis section by the deformation section, a stenosis ring in the human body ureterostenosis section does not need to be broken by supporting, so that the injury to the human body ureter in the ureteroscope lithotripsy is effectively reduced, and the postoperative pain of a patient is reduced.

The invention relates to the technical field of medical drainage equipment, in particular to in-vivo effusion drainage equipment for breast surgery, which comprises a storage rack, a pair of drainage tubes and an overclothes for a patient to wear, two drainage bottles are placed in the storage rack, a box body is arranged at the top of the storage rack, and a driving mechanism is arranged in the middle of the interior of the box body; two first gas distribution mechanisms and two second gas distribution mechanisms are arranged in the box body and are symmetrically arranged relative to the driving mechanism. The first air distribution mechanism is driven by the driving mechanism to work to inflate and deflate the pressing air bag set, automatic pressing can be conducted on the mammary gland portion of an operation area of a patient, effusion can be rubbed away, accumulation of the effusion in mammary gland tissue is avoided, hematoma or blood clots are reduced, and the effusion is discharged more effectively; blood circulation and metabolism of surrounding tissues are promoted through pressing, swelling of an operation area is eliminated, postoperative pain and discomfort of a patient are relieved, swelling of the patient is relieved, and the healing process of the tissues is improved.

The invention relates to the technical field of orthopedic biomedical treatment, in particular to a proximal humerus fracture intramedullary bone cement supporting rod. The bone fracture plate comprises a bone fracture plate body, a plurality of first connecting holes and a plurality of second connecting holes are formed in one side of the bone fracture plate body in a penetrating mode, and solid bone nails are arranged in the first connecting holes. According to the device, bone cement is injected into a marrow cavity from an injection molding channel and an injection molding opening and then solidified into a rod body, the marrow cavity space is tightly filled, supporting structures are synchronously formed on the inner side and the outer side of the humerus through cooperation of a bone fracture plate and a bone cement supporting rod in the marrow cavity space, and therefore stress generated when arms of a patient move is evenly dispersed on the two sides of the humerus; the fixing stability is remarkably improved, the risk of internal fixation failure such as steel plate displacement and screw cutting is effectively reduced, and the bone cement supporting rods can further prevent displacement of fracture blocks, promote fracture repair, relieve extrusion and friction of surrounding tissue of a filling position, reduce inflammatory response and postoperative pain and improve the rehabilitation comfort of a patient.

The invention discloses a nerve postoperative pain monitoring and feedback method and system, and relates to the technical field of medical information, and the method comprises the following components: a data acquisition step, a digital twin model construction step, a pain simulation step, a visualization and interaction step and a feedback and scheme making step. By constructing the digital twinborn model of the postoperative body of the patient, the postoperative physiological structure, the nerve function state and the pain-related physiological mechanism of the patient can be accurately simulated, and based on the model, a doctor can simulate different treatment schemes and pain responses under external stimulation, so that a more personalized pain management scheme is formulated, and the pain management efficiency is improved. According to the personalized management mode, the accuracy of pain management is remarkably improved, postoperative pain of the patient can be relieved more effectively, and the treatment experience and satisfaction degree of the patient are improved.

The present invention is directed to novel compounds that inhibit Nav1.8 sodium channels, methods of making, and methods of using thereof. The present disclosure is further directed to administering the disclosed compounds as therapeutic solutions for chronic pain, primary pain, idiopathic pain, gastrointestinal pain, neuropathic pain, musculoskeletal pain, acute pain, inflammatory pain, cancer-related pain, idiopathic pain, postoperative pain, visceral pain, multiple sclerosis, Summer-Marr-Tuff syndrome, incontinence, pathological cough, or arrhythmia to a subject in need thereof.

The invention discloses a surgical guide plate and a manufacturing method thereof.The surgical guide plate comprises a plate body, at least two guide grooves are formed in the plate body, the guide grooves penetrate through the plate body, the guide grooves are communicated with one another and form an included angle, and the included angle is an osteotomy included angle; the positioning part is arranged on the edge of the plate body, and the positioning part is used for positioning the relative position between two bone blocks after osteotomy. By the adoption of the scheme, the guide grooves penetrating through the plate body can guide the osteotomy path of an osteotomy tool such as a swing saw blade or a milling cutter in an operation, the guide grooves communicate with one another, the osteotomy included angle is provided, and the osteotomy accuracy is improved. The positioning part can position the relative positions of the two bone blocks after osteotomy, so that the accuracy of bone block positioning is improved, the treatment effect of operation deformity correction is improved, and postoperative pain is reduced. In addition, the positioning part is arranged at the edge of the plate body, so that the edge of the plate body can be used for positioning.

The invention belongs to the technical field of traditional Chinese medicine surgery postoperative pain management, and particularly relates to a traditional Chinese medicine surgery postoperative pain management system and method. The postoperative pain risk level can be evaluated more accurately by collecting and analyzing the clinical data information of the patient, so that the most suitable pain management measure is quickly matched for the patient to be determined, the pain management is more personalized and accurate, the pain feedback data of the patient is monitored in real time, the intervention measure is adjusted according to the data, and the pain management accuracy is improved. The system can effectively reduce the pain feeling of a patient, improves the life quality of the patient, can help a doctor make a more reasonable judgment in the aspect of pain management through real-time monitoring and adjustment of intervention measures, reduces the waste of medical resources, and improves the medical efficiency.

The application relates to the technical field of medical information, and discloses a postoperative pain rehabilitation nursing data management system for a rehabilitation medical department, which comprises nine processing modules. A multidimensional data dynamic acquisition module is responsible for collecting postoperative pain related data of patients. A cross-platform data interaction module realizes data intercommunication and synchronization among multiple platforms in the system. A data encryption module performs encryption processing on collected sensitive data. A data analysis module calculates a pain comprehensive score and a rehabilitation progress index. A pain risk real-time early warning module performs real-time monitoring on the pain condition of a patient. An intelligent intervention scheme generation module generates a personalized pain intervention scheme. A pain rehabilitation evaluation module performs systematic evaluation on the pain rehabilitation process of a patient. A nursing feedback module collects feedback information of a patient on pain nursing service. A system emergency disaster recovery module provides a system-level disaster recovery backup and emergency response mechanism.

The utility model belongs to the technical field of medical instruments, and relates to a microneedle type meniscus suture device which comprises a handheld handle, an ejector pin and a plurality of loops, the ejector pin is arranged on the handheld handle, the front end of the ejector pin is movably arranged, the loops are sequentially arranged at the front end of the ejector pin in a sleeving mode in the moving direction, the front ends of the loops are sharp, and sutures are arranged between the loops. A one-way limiting structure is arranged between the front end of the ejector pin and the inner wall of the loop, so that the front end of the ejector pin can support the loop and retreat from the loop. Compared with the prior art, the microneedle type meniscus suturing device has the advantages that the operation can be performed with a smaller incision, the postoperative pain is relieved, the recovery time is shortened, and the overall influence of the operation on the body of a patient is remarkably reduced.

The application discloses a tibial prosthesis and a knee joint prosthesis with the same. The tibial prosthesis comprises a patellar ligament attachment surface, a lateral collateral ligament attachment surface and a medial collateral ligament attachment surface, and the surface roughness of at least one of the patellar ligament attachment surface, the lateral collateral ligament attachment surface and the medial collateral ligament attachment surface is less than or equal to a preset value. The tibial prosthesis has the advantages of small friction, low wear, no inflammation and pain, significantly reduced postoperative pain and discomfort, facilitated recovery of the patient, effectively maintained stability and function of the knee joint, long service life and the like.

The present application belongs to the field of pharmaceutical preparations, and particularly relates to a sustained-release analgesic pharmaceutical composition, a method for preparing same, and use thereof. The pharmaceutical composition of the present application comprises a drug, a delivery carrier, and a release regulator. The drug is selected from at least one of a local anesthetic and a non-steroidal anti-inflammatory drug. The release regulator is selected from a phospholipid compound. The delivery carrier is selected from a saccharide and an esterified form thereof. According to the present application, the coaction of the phospholipid compound and the delivery carrier can increase the plasma drug concentration upon the initial release in vivo, reduce the time to peak, enhance the analgesic effect in the early stage after a surgery, and ensure the long-term release of the drug, thus effectively relieving the postoperative pain, reducing the administration frequency, and promoting skin wound healing. The use of a specific solubilizer provides good stability for the drug and prevents precipitation. The composition can be administered through the wound, making it easy to use.

The invention relates to the technical field of image analysis, in particular to an anesthesia post-operation pain assessment method in combination with facial expressions of a patient. An optical flow method is adopted to analyze pixel motion of a facial image, optical flow vectors and information points are obtained, and facial expression changes are quantitatively captured. In view of information point validity differences, facial feature points are screened to reduce data redundancy. And in consideration of the facial structure difference of the patient, the traction characteristics of the optical flow vector are analyzed, and the traction direction of the image block is determined. Pain expressions such as eye eyebrow closeness and the like can be represented by the traction direction. By analyzing the distribution confusion degree and difference in the traction direction, the facial pain index is determined, and accurate reference is provided for pain assessment. And finally, screening a data set based on the facial images of multiple patients and pain indexes, training a neural network, and establishing a mapping relation between facial expressions and pain degrees. According to the method, the pain assessment accuracy is improved, the assessment efficiency is also remarkably improved, and automatic pain assessment of the facial image of the patient to be tested is realized.

The invention discloses a CYP3A4 postoperative intercostal nerve block puncture injection supporting device, and relates to the technical field of intercostal nerve block, the CYP3A4 postoperative intercostal nerve block puncture injection supporting device comprises a supporting frame, a concentric-square-shaped cavity is formed in the supporting frame, a soft support is fixedly connected to the rear side of the supporting frame, patches are symmetrically and fixedly connected to the two sides of the soft support, and uncovering pieces are movably bonded to the sides, away from the supporting frame, of the patches; the device further comprises a disinfection mechanism, a power assisting mechanism and a puncture injection auxiliary mechanism, the disinfection mechanism is arranged on the rear side of the supporting frame, the power assisting mechanism is arranged in the concentric-square-shaped cavity, and the puncture injection auxiliary mechanism is arranged on the front side of the supporting frame. The situation that when medical staff conduct puncture injection on the intercostal skin of a patient, the puncture needle deviates from the target position in the intercostal space of the patient or mistakenly penetrates through other tissue, and consequently local anesthetic medicine is injected into a wrong area is avoided, and the effect of relieving postoperative pain through medicine injection is guaranteed.

The utility model provides a pharyngeal ice bag, which comprises a middle ice bag containing sleeve bag, which is a rectangular open-top pocket structure, an ice bag is placed in the middle ice bag containing sleeve bag, the inner part of the ice bag is divided into multiple small compartments, each small compartment contains a polymer gel, and a set of elastic fixing belts, which comprises two pairs of elastic connecting belts arranged on both sides of the middle ice bag containing sleeve bag, the outer surface of the left strap of each pair of elastic connecting belts is provided with a Velcro surface, and the inner surface of the right strap is provided with a Velcro hook surface matched with the Velcro surface. The utility model has the advantages that it is used for preventing postoperative hemorrhage of the pharynx and relieving postoperative pain of patients. The utility model solves the problem that the pharyngeal ice bag is not easy to fix, and the method is simple and practical.

The invention discloses wearable pain relieving equipment and a remote monitoring system thereof. The wearable pain relieving equipment comprises a multi-mode physiological sensor array, a data fusion processing module, a control module, a transcutaneous electrical stimulation output module, a communication module and the remote monitoring system. The multi-mode sensor array collects myoelectricity, skin conductance, body surface temperature, heart rate, brain oxygen and other pain related physiological parameters, the data fusion module generates a pain estimated value, the control module dynamically adjusts the stimulation intensity based on a PID + differential compensation algorithm, and the transcutaneous electrical stimulation module outputs current to intervene in pain. The communication module uploads data to a remote monitoring system, and medical staff can monitor and remotely adjust parameters in real time through a cloud platform. The system realizes real-time monitoring, intelligent control and remote intervention of pain, has the advantages of personalized treatment, data safety, expandability and the like, and is suitable for scenes of postoperative pain management, chronic neuralgia and the like.

The invention discloses an inflatable heating shoulder pad capable of preventing hypothermia in an operation, and belongs to the field of medical instruments. Comprising a folding mounting mechanism, and shoulder pad mechanisms are arranged in front of and behind the folding mounting mechanism; the folding mounting mechanism comprises two connecting pieces, two steering heads are rotationally connected between the two connecting pieces through rotating shafts, and two extension rods are fixedly connected to the left sides of the steering heads; the problem of compression injury of an existing shoulder rest is effectively solved, the comfort level of a patient in an operation is improved, flexible supporting of the shoulders of the patient is achieved through the inflatable air bag, traditional hard and semi-hard shoulder rests are replaced, shoulder blood circulation blocking caused by long-term compression can be avoided, uncomfortable symptoms such as shoulder ache, stiffness and numbness after the patient is awakened are reduced, and the patient can be prevented from being injured. Meanwhile, skin injury risks such as skin redness, damage and pressure sores caused by local compression are reduced, postoperative pain of a patient is relieved, and the recovery period is shortened.

Disclosed herein is a pharmaceutical composition comprising diltiazem hydrochloride. The composition is preferably formulated as a gel and contains diltiazem hydrochloride together with excipients such as propylene glycol, tartaric acid, and a gel matrix. Also disclosed are a method for preparing the composition and a method for treating anal fissures and / or postoperative pain associated with anal fissures or hemorrhoids.

The invention discloses an intelligent monitoring and intervening system for postoperative pain of children, and belongs to the technical field of medical monitoring. The system comprises a state perception and discretization module, an atomization intervention decision module, an intervention execution and effect monitoring module and a value table asynchronous updating module. The system obtains and discretizes the child patient state in real time through a state perception and discretization module so as to generate a state index; the atomization intervention decision module determines an optimal intervention action through one-time atomization query operation on the basis of the state index; the intervention execution and effect monitoring module is responsible for executing the action and monitoring the effect; and finally, the value table asynchronous updating module asynchronously updates the intervention strategy according to the intervention effect. According to the method, the decision delay is reduced by compressing the complex decision process into the atomized table look-up operation, meanwhile, adaptive optimization of the intervention strategy is achieved through an asynchronous value updating mechanism, and the problems that in the prior art, intervention measures are poor in adaptability and high in response delay are solved.

The invention relates to the field of medical instruments, in particular to a differentiated tibial plateau prosthesis system which comprises a plateau base, an inner side gasket, an outer side gasket and a central stand column. The platform base is provided with an inner side platform, a stand column platform and an outer side platform, and the stand column platform is located between the inner side platform and the outer side platform; the inner gasket is connected to the inner platform, the outer gasket is connected to the outer platform, and the central stand column is connected to the stand column platform; in the preset direction, the height of the outer side platform is larger than that of the inner side platform, and the inner side platform is flush with the stand column platform. The differentiated tibial plateau prosthesis system is matched with an artificial thighbone prosthesis for use, can effectively retain the bone mass of the proximal end of the tibia on the outer side of the knee joint, enables gaps between the inner side and the outer side of the knee joint which are originally large in difference to be balanced, reduces the requirement for releasing soft tissue on the inner side, avoids excessive releasing and stripping of the soft tissue of the knee joint, relieves the degree of postoperative pain, and improves the patient compliance. And the postoperative rehabilitation process is accelerated.

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a gynecological tumor operation picking device which comprises a connecting plate, a handle is fixedly connected to one end of the connecting plate, a sliding block is slidably connected to one side of the connecting plate, a displacement plate is fixedly connected to one side of the sliding block, clamping rods are slidably connected to the two sides of the displacement plate, and the clamping rods are slidably connected to the two sides of the displacement plate. The end part of the clamping rod is fixedly connected with a picking block; the device further comprises a picking and storing assembly. According to the tumor picking and storing device, by means of the picking and storing assembly, every time one tumor is picked, the tumor can be placed in the storing barrel, each tumor has an independent placing area, and the situation that the placed tumor falls out until all the tumors are picked due to the fact that the next tumor is placed is avoided. In the whole process, the picking block does not need to go in and out of the body of a patient repeatedly, so that the operation time is remarkably shortened, meanwhile, additional trauma caused by frequent friction of incision tissue is avoided, and the pain degree of the patient after an operation is relieved.

The present invention relates to a dental drain tube, and more particularly, to a dental drain tube for oral use, and more particularly, to a dental drain tube for oral use, which can prevent blood accumulation of abscesses and infections in infected sites where abscesses such as abscesses and cellulitis are formed in dentistry, oral maxillofacial surgery or the like, and sites where swelling is expected to be severe after surgery. The present invention provides a drain tube for discharging to the outside, and discharges abscess, tissue or the drain tube from the most inconvenient position of post-operation discharge. The present invention relates to a dental oral drain tube capable of shortening the recovery time, for which the present invention extends in the longitudinal direction, has a radiation-impermeable line on either the outer surface or the inner surface, is inserted into a desired site of postoperative pain and swelling, fevers at a surgical site, and discharges to the outside. A channel extending along the length direction and providing channels for movement of pus, interstitial fluid or blood to prevent accumulation of interstitial fluid or blood; a drainage hole formed along the longitudinal direction of the main body and through which pus, interstitial fluid, or blood outside the main body flows into the channel; forming a plurality of groove lines on the outer surface of the main body to limit the moving direction of the main body; the method is characterized by including.

The present invention discloses a minimally invasive combined intervertebral fusion device, belonging to the technical field of intervertebral fusion devices. The minimally invasive combined intervertebral fusion device comprises two symmetrical fusion device main shells, one side of the two fusion device main shells is provided with a fusion device sub-shell; a fixing mechanism is installed in the fusion device sub-shell, a first supporting mechanism is installed in the center of the two fusion device main shells, and a second supporting mechanism is installed in the first supporting mechanism. The present invention can adjust the expansion amplitude of the two sides of the two fusion device main shells according to the specific intervertebral size by designing the fusion device main shell, the first supporting mechanism and the second supporting mechanism, so as to fully fit the fusion device with the vertebral body, greatly improve the fusion effect of the two vertebral bodies, and reduce the patient's postoperative pain.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a sustained-release analgesic pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises a drug, a delivery carrier and a release regulator, the medicine is selected from at least one of local anesthetics and non-steroidal anti-inflammatory drugs; the release regulator is selected from phospholipid compounds; the delivery carrier is selected from saccharides and esters thereof. According to the invention, the phospholipid compound is adopted as the release regulator, and the phospholipid compound and the delivery carrier act together to increase the initial release blood concentration of the drug in vivo, shorten the peak time of the blood concentration, enhance the analgesic drug effect at the initial stage of the operation, maintain the long-acting release of the drug, effectively relieve the postoperative pain, reduce the administration frequency, and meanwhile, improve the bioavailability of the drug. The effects of promoting skin wound healing and repairing are also achieved; a specific type of solubilizer is adopted, so that the medicine has good stability and is not easy to separate out; in addition, the pharmaceutical composition disclosed by the invention can be directly administrated through a wound and is convenient to use.

A composition comprising capsaicin or a capsacinoid is used in a method for postoperative pain control. The composition is administered to a site intended for surgery in a patient at least one day before surgery is actually performed.

This invention discloses a surgical guide and its manufacturing method. The surgical guide includes: a plate body with at least two guide grooves penetrating the plate body and interconnected at an angle, the angle being the osteotomy angle; and a positioning part located at the edge of the plate body, used to locate the relative position between two bone fragments after osteotomy. Using this design, the guide grooves penetrating the plate body guide the osteotomy path of osteotomy tools during surgery, such as oscillating saw blades or milling cutters. Furthermore, the interconnected guide grooves provide the osteotomy angle, improving the accuracy of osteotomy. The positioning part can locate the relative position of the two bone fragments after osteotomy, thereby improving the accuracy of bone fragment positioning, thus improving the therapeutic effect of surgical correction of deformities and reducing postoperative pain. Additionally, the positioning part is located at the edge of the plate body, allowing for positioning using the edge of the plate body.

The application relates to the technical field of data processing, and discloses a postoperative pain recognition system and method based on electroencephalogram signals, which comprises an electroencephalogram acquisition module, a signal preprocessing module, a pain intensity analysis module and an output and control module; the electroencephalogram acquisition module is used for collecting original electroencephalogram signals of a postoperative patient according to a preset sampling rate; the signal preprocessing module is used for filtering and denoising the original electroencephalogram signals and removing abnormal sections based on dynamic time warping to obtain preprocessed electroencephalogram signals; the pain intensity analysis module is used for deploying a deep neural network model, receiving the preprocessed electroencephalogram signals, inputting the preprocessed electroencephalogram signals into the deep neural network model and outputting a pain intensity grade; and the output and control module is used for displaying or transmitting the pain intensity grade and converting the pain intensity grade into a control instruction. The application fuses wavelet convolution and LSTM dynamic modeling, and improves the pain recognition and distinction precision.

This invention provides a method and system for collecting and analyzing acupressure massage data for postoperative pain, belonging to the field of data analysis technology. It includes acquiring and fusing patients' physiological characteristics and acupressure feedback data to construct a time-varying pain sensitivity map. Based on the map, initial intervention parameters are calculated and an effect decay function is constructed to dynamically adjust the massage cycle to generate a scheduling sequence. The acupressure combination is rotated and adjusted based on the cumulative stimulus tolerance value, and control commands are output to drive the massage terminal. This invention achieves personalized and dynamic postoperative pain management, improving analgesic efficacy and patient comfort.

The invention discloses a method for tightening a vagina by using a biological band, which comprises the following steps: S1, preparing the biological band which is made of decellularized allogeneic dermis and mainly comprises elastin, fibronectin, hyaluronic acid, I-type collagen, III-type collagen, IV-type collagen and VII-type collagen; s2, the biological bridle is in a strip shape of a 3D structure, the specification of the biological bridle is 1 * 15 cm, and in the using process, the biological bridle is cut into different lengths according to using requirements. The problems that in a traditional vaginal contraction operation, part of vaginal mucosa or muscular layer needs to be cut off through an incision, and suturing and tightening are conducted, so that tissue damage is large, postoperative pain is obvious, the recovery period is long, mucosa nerve damage, sexual sensitivity reduction, scar formation and the like are likely to occur after operation, and the vaginal function and life quality are affected are solved.

The present invention discloses a low-molecular-weight local anesthetic gel, liposomes, and preparation methods thereof. The raw materials of the low-molecular-weight local anesthetic gel include: a local anesthetic, a bile salt, an aqueous solvent, or a buffer; the local anesthetic is selected from an amide local anesthetic; and the bile salt is selected from at least one of sodium cholate, sodium deoxycholate, sodium chenodeoxycholate, sodium lithocholic acid, sodium ursocholic acid, sodium ursodeoxycholate, sodium glycodeoxycholate, sodium taurolithocholic acid, sodium glycotaurocholate, sodium glycochenodeoxycholate, sodium phenylpropanecholate, sodium casocholic acid, sodium leukocholic acid, bile acid dimer, bile acid side chain amino acid conjugate, bile acid side chain PEG conjugate, and bile acid side chain glucose conjugate. The preparation process of the gel and liposome of the present invention is simple and controllable, and can achieve the purpose of postoperative pain management after a single administration.