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223 results about "Tissue fluid" patented technology

Transudate which surrounds cells within a tissue.

Antiskid rotatable bent three-blade forceps with suction function for laparoscopic surgery

The utility model relates to the technical field of medical instruments, in particular to a pair of anti-slip rotatable bent three-blade forceps with a suction function for laparoscopic surgery, which comprises a forceps seat, blades, an opening mechanism, a forceps tube, a rotating mechanism, an inner tube, a rotating wheel, a pull rod, a pull wire, a handle and a suction tube, the blade is connected with the clamp seat through an opening mechanism, a rotating opening is formed in the head end of the clamp pipe, the clamp seat is installed on the rotating opening, the inner pipe is located in a pipe cavity of the clamp pipe, a rotating hole is formed in the tail end of the clamp pipe, the inner pipe penetrates through the rotating hole, the head end of the inner pipe is connected with the clamp seat through a rotating mechanism, and the rotating axis of the clamp seat is perpendicular to the rotating axis of the inner pipe. The utility model has the advantages that the front end of the blade is provided with the arc-shaped hook claw, so that deep pelvic tissues can be firmly grasped, and slipping can be effectively avoided; the rotating wheel is operated to adjust the angle of the clamp seat at the rotating opening through the inner pipe and the rotating mechanism, so that the traction effect of the blades is improved; a special suction channel is arranged in the forceps tube and used for sucking smoke, blood and interstitial fluid generated in the operation process.
Owner:FUJIAN MEDICAL UNIV UNION HOSPITAL

Multi-dimensional data processing method and system for intelligent scoring of emergency patients

The embodiment of the invention provides a multi-dimensional data processing method and system for intelligent scoring of emergency patients. The method comprises the following steps: acquiring dynamic temperature data and humidity fluctuation data of a burn wound surface through a flexible wearable monitoring device; inputting the time sequence change of the dynamic temperature data into a temperature-drug release model to generate drug concentration distribution; constructing an infection diffusion map taking the anatomical structure as a topological reference, wherein the infection diffusion map comprises an edge attribute representing the flow direction of tissue fluid and a node attribute representing a necrotic region; combining the metabolic rate parameter in the node attribute and the fluid resistance parameter in the edge attribute, iteratively updating the infection propagation intensity, and generating a weight distribution diagram; matching burn depth grading standards according to geometric deformation characteristics and gradient attenuation trends of the weight distribution map, and generating infection risk dynamic scores integrated with drug concentration distribution feedback. According to the technical scheme provided by the embodiment of the invention, the multi-dimensional data processing efficiency and precision can be improved.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Microneedle patch for wearable electrochemical luminescence sensing equipment and application of microneedle patch

The invention belongs to the technical field of electrochemical luminescence detection equipment, and particularly relates to a microneedle patch for wearable electrochemical luminescence sensing equipment and application of the microneedle patch. The microneedle patch comprises a microneedle base and a microneedle array, the microneedle base is divided into a left area, a middle area and a right area through two parallel grooves; the middle area is conductive and light-transmitting, and the left and right areas are conductive and light-proof; the microneedle arrays are arranged in the three areas and are all subjected to conductive treatment; the three areas are separated by grooves and are insulated from one another and are not conductive; and the surface in each area has conductive performance, so that electric signals can be conducted. The light-emitting sensing equipment takes the microneedle patch as a real-time acquisition tool of a tissue fluid sample, detects the concentration of cTnI in the tissue fluid on line, realizes real-time monitoring of a marker cTnI of myocardial injury and acute myocardial infarction in vivo, has the characteristics of high detection sensitivity, portability, simplicity in operation, low cost and the like, and realizes online in-situ monitoring of wearable electrochemical luminescence of a patient.
Owner:FUDAN UNIVERSITY

Coronary plaque biomechanical property calculation method

The invention discloses a coronary plaque biomechanical property calculation method, and belongs to the field of computational biofluid mechanics in biomedical engineering. According to the method, the influence of cardiac pulsation, coronary blood vessel complex geometric distribution characteristics and coronary plaque composition factors is integrally considered, and the coronary plaque biomechanical characteristics are calculated; wherein the number of the fluid computational domains is two, and the two fluid computational domains are respectively a coronary vessel intracavity blood flow area and a plaque tissue fluid flow area surrounded by a fibrous membrane and a blood vessel; the two structural computational domains are respectively an elastic blood vessel wall and an ultrathin flexible plaque fiber membrane; the plaque fiber membrane generates deformation movement under the pressure of blood in blood vessels on two sides and tissue fluid in the plaque; the motion of the coronary plaque fibrous membrane is described by adopting an independently researched and developed immersion film method, and compared with a traditional coronary plaque biomechanical characteristic calculation method, the method has better information integrity, better accuracy and wider applicability.
Owner:DALIAN UNIV OF TECH +1

Histotripsy therapy systems and methods for the treatment of brain tissue

A histotripsy therapy system configured for the treatment of brain tissue is provided, which may include any number of features. In one embodiment, the system includes an ultrasound therapy transducer, a drainage catheter, and a plurality of piezoelectric sensors disposed in the drainage catheter. The ultrasound therapy is configured to transmit ultrasound pulses into the brain to generate cavitation that liquefies a target tissue in the brain. The drainage catheter is configured to detect the ultrasound pulses. An aberration correction algorithm can be executed by the system based on the ultrasound pulses measured by the drainage catheter to automatically correct for an aberration effect caused by the ultrasound pulses passing through a skullcap of the patient.
Owner:THE RGT UNIV OF MICHIGAN

Preparation method of gas-jet mineralized collagen-hydrogel microspheres

The invention provides a preparation method of gas-jet mineralized collagen-hydrogel microspheres, and relates to the technical field of biological materials, and the preparation method comprises the following steps: dissolving collagen in a phosphate solution, dropwise adding the phosphate solution and a CaCl2 solution into a continuously stirred alkaline solution together, reacting for 12-48 hours, centrifugally collecting a precipitate, washing with water, centrifuging, and freeze-drying to obtain mineralized collagen; the method comprises the following steps: dissolving mineralized collagen and sodium alginate in deionized water, spraying the solution into a CaCl2 solution through a gas spraying spinning head by adopting a gas spraying technology, collecting microspheres, and repeatedly cleaning by adopting deionized water to obtain the gas spraying mineralized collagen-hydrogel microspheres. Mineralized collagen is encapsulated and loaded through microspheres, so that interferences of tissue fluid are isolated, and non-specific aggregation is reduced; optimizing the ratio of mineralized collagen, and directionally inducing stem cells to differentiate; the diameter of the microsphere is accurately controlled by regulating and controlling gas injection parameters to adapt to different wounds; active ingredients are controlled according to needs through a microsphere cross-linked network, and the multi-stage requirements of subcutaneous repair are met.
Owner:JIAXING RUIQING MEDICAL TECH CO LTD

Non-invasive tissue fluid lactic acid dynamic monitoring method

The invention provides a non-invasive tissue fluid lactic acid dynamic monitoring method. The method comprises the following steps: establishing a relation model of epidermal and subcutaneous lactic acid concentrations; steady-state current values under different epidermal lactic acid concentrations are obtained through in-vitro experiments, and then the function relation between the steady-state current values and the epidermal lactic acid concentrations is obtained; net current values under different subcutaneous lactic acid concentrations are obtained through human body experiments, a function relationship between the net current values and the subcutaneous lactic acid concentrations is established, and the function relationship can be used for a subsequent transdermal extraction detection process; substituting the measured epidermal lactic acid concentration into a relation model of epidermal and subcutaneous lactic acid concentrations to obtain an accurate concentration value of tissue fluid lactic acid monitoring; according to the method, in the dynamic real-time monitoring process of the lactic acid concentration of the tissue fluid, the concentration of the lactic acid extracted from the epidermis measured by the lactic acid sensor can be converted into the real-time and accurate lactic acid concentration of the subcutaneous tissue fluid, and rapid, painless, infection-free and continuous monitoring of the lactic acid level of the subcutaneous tissue fluid can be achieved.
Owner:TIANJIN UNIV

Neurosurgery interventional therapy implantation dosing device

The invention discloses a neurosurgery interventional therapy implantation dosing device, and belongs to the field of medical instruments, the neurosurgery interventional therapy implantation dosing device comprises an injection seat, the injection seat is provided with a first storage cavity for storing liquid medicine, the injection seat is provided with a catheter communicated with the first storage cavity, and the injection seat is fixedly provided with a first silica gel pad; the injection seat is provided with a flow guide assembly, the flow guide assembly is used for collecting tissue fluid generated by body rejection, the injection mechanism is fixed on an arm of a patient through a binding assembly, the injection mechanism is matched with the driving mechanism to add a medicament into the injection seat, and a flow guide groove in the outer wall of the injection seat guides the peripheral tissue fluid to flow. The supporting net facilitates the tissue fluid to enter the second storage cavity along the flow guide grooves, the arc-shaped plates in the second storage cavity are matched with the flow guide holes in the arc-shaped plates, the tissue fluid smoothly flows into the second storage cavity, and the structure constructs an efficient drainage path to efficiently collect the tissue fluid.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

A bladder tumor specimen extractor

The application discloses a bladder tumor specimen extractor which comprises an adjusting transmission assembly capable of controlling preliminary cutting, a separating assembly capable of separating a tissue part and a liquid part of the bladder tumor and an operating handle. The application belongs to the technical field of bladder tumor surgery. When the bladder tumor temporarily stays on a tissue liquid passing layer, the removed bladder tumor can be punctured by a plurality of groups of puncture heads, so that the tissue part of the bladder tumor is blocked by the tissue liquid passing layer, and the tissue liquid and the plasma part of the bladder tumor can pass through the tissue liquid passing layer and enter a liquid storage bag. After sampling is completed, medical staff can take out the liquid storage bag to sample the tissue liquid and the plasma part of the bladder tumor, and the tissue part of the bladder tumor can be sampled from the tissue liquid passing layer. The application provides a brand-new bladder tumor sampling experience, greatly reduces the possibility of tissue liquid and plasma remaining in the bladder and brings convenience to medical staff.
Owner:SHANGHAI PUDONG HOSPITAL

A wearable hyperthermia and drainage device for lymphedema

ActiveCN120093578BTissue fluidLymphedema
The application discloses a kind of lymphedema wearable type baking therapy drainage devices, including pressure sleeve, pressure sleeve includes multiple independent control outer layer air bag and multiple independent control inner layer air bag, outer layer air bag and inner layer air bag staggered arrangement and along the axial distribution of limb;Each outer layer air bag and each inner layer air bag independent control, along the direction of far end to near end, in turn, air bag is inflated and deflated control, to complete a cycle air bag progressive drainage pressurization.The pressure sleeve of the application has double-layer air bag, each air bag is independently controlled, and can extrude tissue fluid from far end to near end, so that tissue fluid moves to near end, and pushes and extrudes tissue fluid from limb to trunk direction.Because inner layer air bag and outer layer air bag are staggered arrangement, can avoid effusion to remain in the gap of adjacent annular air bag;The pressure sleeve of the application is provided with inner support tube, and forms circumferential block.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Microneedle diagnosis and treatment device

PendingCN120324768AMicroneedlesMedical devicesSynovial hyperplasiaIntegrated monitoring
The microneedle diagnosis and treatment device comprises a sensing microneedle, a photo-thermal microneedle, a light source module, an electrochemical sensing module, a main control module and an upper computer, the sensing microneedle and the photo-thermal microneedle are respectively and electrically connected with the electrochemical sensing module, the light source module and the electrochemical sensing module are respectively and electrically connected with the main control module, and the main control module is in communication connection with the upper computer. The sensing microneedle disclosed by the invention is matched with the electrochemical sensing module and the main control module, so that the change of the glucose level in joint tissue fluid can be monitored in real time, and monitored data is transmitted to an upper computer through the main control module; a user can utilize the host computer to cooperate with the master control module to control the operation of the light source module, so that the photo-thermal microneedle absorbs light energy and generates high temperature, thereby inhibiting synovial hyperplasia of tissue fluid and achieving the purpose of integration of monitoring and treatment, the structure is simple, and closed-loop management of monitoring-evaluation-treatment can be realized.
Owner:ZHONGBEI UNIV

Absorbable self-repairing suture line for maintaining stability of mechanical biological microenvironment and preparation method of absorbable self-repairing suture line

PendingCN121513254ASuture equipmentsAbsorbable polymersTissue repair
The invention relates to the technical field of biological materials, and provides an absorbable self-repairing suture line for maintaining the stability of a mechanical biological microenvironment and a preparation method of the absorbable self-repairing suture line. According to the suture line, an absorbable high polymer material is adopted as a matrix, and PLA microcapsules containing a medical-grade cyanoacrylate n-octyl ester repairing agent are uniformly dispersed in the matrix through a melt blending spinning process. When the suture line generates microcracks at dynamic tissue parts such as cardiovascular and digestive tracts due to periodic stress, the stress at the tip of the cracks enables the microcapsules to be broken to release the repairing agent, rapid in-situ polymerization occurs under triggering of tissue fluid, the self-repairing efficiency of 90% or above is achieved, and the strength retention rate of 95% or above is maintained in the key rehabilitation period of the suture line. The defect that a traditional absorbable suture line is prone to fatigue fracture in a dynamic environment is overcome, the mechanical integrity is actively maintained through an intelligent self-repairing mechanism, all components can be completely degraded and absorbed, and a safer and more reliable solution is provided for dynamic tissue repairing.
Owner:JINHUA YUNHONG LIFE TECHNOLOGY CO LTD

Medical blood sampling device

This utility model relates to the field of blood sampling technology, specifically to a medical blood sampling device, comprising: a base plate, on which a support frame is fixedly mounted; and a driving assembly, which includes a rotating wheel disposed above the base plate and on one side of the support frame, with multiple collection cylinders slidably mounted in a circumferential array inside the rotating wheel. Through the design of the collection assembly, during blood sampling after a patient's finger is punctured, a rubber column can be used to squeeze and rub the sides of the fingertip, accelerating the flow of blood from the puncture point and dripping blood containing tissue fluid. The roller design allows for the enlargement of the roller diameter after the first drop of blood containing tissue fluid drips from the puncture point, lifting the finger and facilitating subsequent sampling. The dripped blood can be collected through the collection cylinders, preventing it from dripping to other places and causing inconvenience for subsequent cleaning.
Owner:LUAN SHINING NEW MATERIALS TECHNOLOGY CO LTD

Rice leaf disease identification sampler

The invention discloses a rice leaf disease identification sampler, and belongs to the technical field of plant sampling. The rice leaf disease recognition sampler comprises a reciprocating mechanism and a first cutter, and further comprises a second cutter which is of a polygon prism structure, and when the reciprocating mechanism drives the first cutter to move towards one side close to the second cutter, a cutting edge of the first cutter can be attached to the side wall, close to one side of the first cutter, of the second cutter; the intermittent rotating mechanism is used for driving the second cutter to rotate until the next side wall of the second cutter faces the first cutter when the cutting edge of the first cutter is separated from the side wall of the second cutter; the brushing mechanism comprises a first brush and a disinfectant spraying part, and the disinfectant spraying part is used for spraying disinfectant to the first brush. The rice leaf disease identification sampler can prevent tissue fluid or cell fluid of diseased leaves from remaining on the cutting knife when sampling the diseased leaves of rice, thereby preventing rice viruses from forming cross infection among different kinds of rice.
Owner:XINYANG AGRI & FORESTRY UNIV

Periodontal disease prevention device

ActiveJP7743958B1Tooth cleaningINTRAGINGIVALBristle
To provide a device for preventing periodontal disease, which aims to prevent periodontal disease by increasing the blood flow in the gums through brushing with a toothbrush, rectifying the tissue fluid produced in the gums and guiding it to the attached subepithelial connective tissue, and causing the tissue fluid to seep into the gingival sulcus through the gaps between attached epithelial cells, thereby generating a pseudo self-cleaning action of the gingival sulcus. [Solution] Using a motor for an arrow feather-shaped brush, the arrow feather-shaped brush is continuously rotated from the attached gum through the cervical area toward the gingival sulcus opening, with the product of the number of rows of brush bristles that make up the feather portion of the arrow feather-shaped brush 1 and the number of rotations per minute of the motor being in the range of 240 times per minute or less, and the rotating arrow feather-shaped brush is vibrated using a vibration motor 12.
Owner:菅野康幸

Low-frequency magnetic field test system based on human body model

The utility model provides a human body model-based low-frequency magnetic field test system, which comprises a human body model, a plurality of organ models and a data acquisition instrument are arranged in the human body model, each organ model is provided with a plurality of magnetic field probes, and the data acquisition instrument is arranged below the organ models and connected with the magnetic field probes. The human body model is filled with an electrolyte solution, and the organ model and the data acquisition instrument are both placed in the electrolyte solution. The magnetic field probe solves the problems that in the prior art, a used magnetic field probe with a fixed shape and a fixed size is greatly different from an actual human organ, and the magnetic field environment neglects the influence of human skin and in-vivo tissue fluid, so that measured magnetic field data is inaccurate.
Owner:CHONGQING VEHICLE TEST & RES INST CO LTD

Simulated human tissue fluid, its preparation method and application

The application provides a kind of simulated human tissue fluid and its preparation method and application, it relates to wireless communication technical field, the simulated human tissue fluid includes: water, 55wt%~75wt% by mass percentage;Ionic inorganic salt, 2wt%~5wt%;Albumin, 10wt%~18wt%;Lipid, 12wt%~20wt%;Non-ionic surfactant, 2wt%~4wt%;Preservative, 0.2wt%~1wt%.Therefore, by water, ionic inorganic salt, albumin, lipid, non-ionic surfactant and preservative cooperate to simulate the skin of human body, so as to be able to carry out APD test in the frequency range of 10GHz~30GHz, and the stability of simulated skin tissue fluid is good, and the cost is lower.
Owner:HONOR DEVICE CO LTD

Tumor-free isolation device for laparoscopic surgery

The utility model relates to a tumor-free isolation device for laparoscopic surgery, and belongs to the technical field of medical instruments. The tumor-free isolation device for the laparoscopic surgery comprises a cannula assembly and a tumor isolation assembly, wherein the tumor isolation assembly is arranged in the cannula assembly in a penetrating manner and extends out of the front end of the cannula assembly; the tumor isolation assembly comprises a connecting pipe, a head rod, a tumor isolation bag and a traction rod, the head rod is hinged to the front end of the connecting pipe, the tumor isolation bag is arranged on the head rod, the traction rod slidably penetrates through the connecting pipe, and the front end of the traction rod is hinged to the head rod; when the traction rod moves back and forth, the head rod can be driven to swing up and down, and the included angle between the opening of the tumor isolation bag and the axis of the connecting pipe is changed. According to the tumor-free isolation device for the laparoscopic surgery, the orientation of the opening of the tumor isolation bag can be automatically changed, so that the opening of the tumor isolation bag is aligned with a focus part, the bearing area is larger, and waste tissue or tissue fluid is not prone to escaping.
Owner:颜海军 +1

System and method for enhanced data analysis with video enabled software tools for medical environments

Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or tools, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register subtle differences in color characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system. Moreover, the new tools are intended to help surgeons better determine the boundaries between healthy and diseased regions during surgical procedures. Various tools are intended to be used in procedures where indocyanine green (ICG) fluorescent dye is used. Intraoperative fluorescence imaging is commonly used during minimally invasive procedures to enable surgeons to visualize tissue perfusion and anatomical structures. The term perfusion refers to the passage of blood and tissue fluid through the capillary bed. Intraoperative fluorescence imaging can also be used to improve visualization of vessels and structures, which, in turn, may reduce the risk of complications during minimally invasive surgeries.
Owner:WADE JACK

Human body implantation depth self-adaptive sensor

The invention relates to the field of medical detection instruments, in particular to a human body implantation depth self-adaptive sensor. Comprising a sensor shell and a probe fixedly connected with the sensor shell, the probe is provided with a plurality of reaction areas located at different axial positions, and the outer side of the probe in the reaction areas is provided with a biological enzyme which is in contact reaction with human body tissue fluid; an induction antenna is arranged on the sensor shell and is used for transmitting a detection electric signal to a human body and receiving a feedback electric signal formed by reflection or conduction of different tissue layers of the human body. Through cooperative work of probe multiple reaction areas, induction antenna positioning and mainboard screening, after battery power supply, an antenna detection signal recognizes a reaction area tissue layer, and a mainboard collects an ideal layer current outflow result, the problem of low detection efficiency caused by tedious and time-consuming operation of manually adjusting the detection depth by medical staff is solved; and the detection stability is improved, the operation threshold is reduced, and individual differences are adapted.
Owner:CHONGQING DAOPU MEDICAL TECHNOLOGY CO LTD

Endoscope puncture sheathing canal inner wall cleaning device based on DaVinci robotic surgery

The utility model relates to an endoscope puncture sheathing canal inner wall cleaning device based on a DaVinci robot operation, which comprises an outer sheathing canal, an inner sheathing canal which is arranged in the outer sheathing canal in a penetrating manner and can axially move relative to the outer sheathing canal, a push-pull mechanism and a cleaning part connected to the other end of the inner sheathing canal, the cleaning part is configured to at least have the characteristic of adsorbing tissue fluid and the shrinkage expansibility; the push-and-pull mechanism comprises a push-and-pull button which is connected to one end of the inner sheath tube and extends out of the outer sheath tube, and the push-and-pull button is configured to move towards a first direction under the action of external force to push the inner sheath tube to axially move outwards in an inner cavity of the outer sheath tube, so that the cleaning component is moved out of the inner cavity of the outer sheath tube and expands outwards in the radial direction; and the push-pull button slides towards a second direction under the action of external force to drive the inner sheath tube to axially move towards the inner cavity of the outer sheath tube, so that the cleaning component is in a compressed state of being radially limited in the inner cavity of the outer sheath tube. The cleaning device for the inner wall of the instrument tube cavity is safe, efficient, simple in structure, clean and free of residues.
Owner:THE UNIVERSITY OF HONG KONG SHENZHEN HOSPITAL

Adjustable cell filter

This utility model discloses an adjustable cell filter, including a filter cover and a connecting sleeve disposed at the bottom of the filter cover. The top of the filter cover is open, and a retaining ring is fixed to the lower circular inner wall of the center of the filter cover. A placement ring is placed at the top of the retaining ring, and a cylindrical filter frame is fixed inside the placement ring. The top of the cylindrical filter frame is open. By adding a novel flow guiding and anti-splash device inside the upper side of the center of the filter cover, located above the cell filter membrane, when tissue fluid is poured in, it is poured into the conical flow guiding and anti-splash cover. Its smooth inner wall allows the tissue fluid to flow slowly, avoiding impact on the cell filter membrane and extending its life. The conical structure can also converge and guide the flow. The flat cylindrical protective cover further buffers the flow, allowing the tissue fluid to fall smoothly onto the cell filter membrane, achieving uniform filtration. The hemispherical diffuser block arches upward to diffuse the tissue fluid, avoiding excessive local pressure that could damage the filter membrane, optimizing distribution, and improving efficiency and quality.
Owner:ZHONGKE HUAXIA BIOMEDICAL RES GRP CO LTD

Medical surgical membrane

The utility model discloses a medical surgical membrane, which comprises a surgical area, a first electrode, a second electrode, a third electrode and a fourth electrode, the collecting pipe is arranged below the operation area; the guiding bag is provided with a first connecting end and a second connecting end which are opposite to each other, the first connecting end is connected with the lower end of the operation area, the second connecting end is connected with the upper end of the collecting pipe, and the width of the guiding bag is gradually reduced in the direction from the first connecting end to the second connecting end; and the filter is detachably connected with the guide bag or the collecting pipe. According to the utility model, the filter is detachable, and when different tissues need to be screened in the operation liquid in an operation, different tissue liquids can be obtained only by replacing different filters without replacing the whole operation membrane, so that the time required for replacing the filter is greatly shortened, and the normal operation of the operation is not delayed.
Owner:NINGBO HAISHU DISTRICT SECOND HOSPITAL

A high sharpness injection needle

The utility model discloses a high sharpness injection needle, including needle tube and needle tip, the needle tip adopts three -stage tapering type multi -edge surface structure, and this three -stage tapering type multi -edge surface structure is composed of main cutting part, transition part and micro blade part, the main cutting part includes three symmetrical distribution's first inclined plane, and every first inclined plane bifurcates two second inclined planes to form transition part, and every second inclined plane bifurcates two third inclined planes to form micro blade part, the needle tip surface is equipped with a plurality of micro -groove, and the third inclined plane intersection of on micro blade part forms nanometer -class blade edge, and this blade edge edge is equipped with periodic micro sawtooth. The utility model discloses a needle tip is three -stage tapering type multi -edge surface structure, and the puncture resistance is reduced in stages, and the pain feeling is reduced, sets up micro sawtooth and can reduce the tissue contact area through " point cutting", and the local stress concentration when puncturing, and then delay passivation, sets up micro -groove and can guide the tissue fluid flow, destroys the negative pressure adsorption effect, and improves the needle insertion smoothness.
Owner:YINGTAN RONGJIA GRP MEDICAL EQUIP IND CO LTD

Anti-drifting peritoneal dialysis pipeline convenient to fix

The invention discloses an anti-drifting peritoneal dialysis pipeline convenient to fix, relates to the technical field of peritoneal dialysis pipelines, and aims to solve the technical problems that a polyester sleeve is insufficient in fixing and anti-traction capacity, and a catheter is prone to shifting and even falling off due to accidental pulling. Comprising a fixing bellyband surrounding the waist and belly, a first dialysis tube arranged at a subcutaneous tunnel section, a fixing mechanism and an auxiliary mechanism. According to the invention, the compressible elastic anchor wing is in a dry and compressed state in the implantation process, rapidly absorbs tissue fluid after implantation to generate hydration expansion and recover an outward expansion form, and is matched with micron-sized pyramid-shaped textures on the surface of the micro-texture biological anchoring area to provide an ideal scaffold for fibroblast attachment and collagen deposition; the catheter can be mechanically interlocked with surrounding abdominal wall fascia and subcutaneous fiber adipose tissue, the initial subcutaneous stability of the dialysis catheter is guaranteed, and the problems that a polyester sleeve is insufficient in fixing and anti-traction capacity, and the catheter is prone to displacement and even disengagement due to accidental pulling are solved.
Owner:WUZHOU WORKERS HOSPITAL

Non-invasive test paper and method for glycosylated hemoglobin

The invention relates to the technical field of non-invasive glycosylated hemoglobin detection, and discloses non-invasive glycosylated hemoglobin detection test paper and method.The non-invasive glycosylated hemoglobin detection test paper comprises a sampling layer, a combination cushion layer is bonded to the lower surface of the sampling layer, and a nitrocellulose membrane layer is bonded to the side face, away from the sampling layer, of the combination cushion layer; a water absorption layer is adhered to one side surface, far away from the combined cushion layer, of the nitrocellulose membrane layer; a PVC bottom plate is adhered to one side surface, far away from the nitrocellulose membrane layer, of the water absorption layer; through cooperation of the structures, the pain feeling during sampling can be reduced, and the tissue fluid collecting efficiency is improved.
Owner:NANTONG DIAGNOS BIOTECH

An aptamer-based microneedle electrochemical biosensor and a preparation method thereof

The application relates to the technical field of electrochemical detection, in particular to a micro-needle electrochemical biosensor based on an aptamer and a preparation method thereof, which is a three-electrode system, the three-electrode system comprises a working electrode, a reference electrode and a counter electrode, and the base materials of the working electrode, the reference electrode and the counter electrode are all polylactic acid micro-needles with a sputtered gold layer; the modification material of the working electrode comprises 6-mercapto-1-hexanol, 3-aminopropyltriethoxysilane, glutaraldehyde, an amino-modified cortisol aptamer and bovine serum albumin. The micro-needle electrochemical biosensor based on the aptamer and the preparation method thereof are adopted to construct a three-electrode micro-needle system for detecting cortisol in tissue fluid, continuous and painless detection can be realized, the compliance of patients is improved, the detection limit is low, the detection range is wide, the sensitivity is high, and the needs of human body for daily detection of cortisol can be met.
Owner:BEIJING UNIV OF CHEM TECH

Gradient pressure-electricity-heat collaborative intervention edema rehabilitation oversleeve

The invention discloses a gradient pressure-electricity-heat collaborative intervention edema rehabilitation oversleeve which comprises an oversleeve body, a portable battery, a temperature module, an electrical stimulation module and a portable force-electricity-heat control module, a plurality of air bags are arranged in the oversleeve body, each air bag is connected with an integrated air path module through a pressure pipe, and the integrated air path module is connected with an integrated air path module through a pressure pipe. Air of different volumes is inflated into each air bag through an air pump of the integrated air path module, the pressure of each part is monitored through a pressure sensor, and when the pressure of each part reaches a set value, air inflation into the air bags is stopped; by adjusting the heating temperature of a heating piece of the temperature module, corresponding arm acupuncture points and muscles are heated, upper limb microcirculation is improved, the acupuncture points are thermally stimulated, and interstitial fluid backflow and wearing comfort of the upper limbs are improved; the electrical stimulation module is arranged on the inner surface of the oversleeve body, and electrical stimulation electrodes of the electrical stimulation module are used for stimulating corresponding arm acupoints and muscles to achieve the physiotherapy effect.
Owner:TIANJIN POLYTECHNIC UNIV +1

Stoma base plate based on three-dimensional liquid diode, stoma detection system and stoma detection algorithm

The invention relates to a stoma base plate based on three-dimensional liquid diodes. The stoma base plate is composed of a liquid transmission layer and an intelligent information acquisition layer. The liquid transmission layer comprises a vertical liquid diode layer which is arranged on the bottom layer close to the skin surface and used for achieving preliminary absorption of sweat or interstitial fluid and one-way transmission in the direction perpendicular to the skin surface; the horizontal liquid diode layer is arranged on the upper layer of the vertical liquid diode and is used for receiving sweat or tissue fluid transmitted by the vertical liquid diode and unidirectionally guiding the sweat or tissue fluid to an edge outlet along the horizontal direction and finally discharging the sweat or tissue fluid; the intelligent information acquisition layer comprises a miniature thermocouple and a miniature borborygmus sensor and covers the upper layer of the horizontal liquid diode layer or the lower layer of the vertical liquid diode layer, and an electrode part of the intelligent information acquisition layer is coupled with sweat.
Owner:WUXI NO 2 PEOPLES HOSPITAL

drainage device

1. The name of the design product: drainage device. 2. The use of the design product: used as tissue fluid drainage and collection device. 3. The design features of the design product: in shape. 4. The picture or photo that best shows the design features: perspective view 1.
Owner:SHENZHEN LONGHUA DISTRICT PEOPLES HOSPITAL