52 results about "Coronary blood vessel" patented technology

Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vessel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.

Methods and apparatus for direct coronary revascularization wherein a transmyocardial passageway is formed between a chamber of the heart and a coronary blood vessel to permit blood to flow therebetween. In some embodiments, the transmyocardial passageway is formed between a chamber of the heart and a coronary vein. The invention includes unstented transmyocardial passageways, as well as transmyocardial passageways wherein protrusive stent devices extend from the transmyocardial passageway into an adjacent coronary vessel or chamber of the heart. The apparatus of the present invention include protrusive stent devices for stenting of transmyocardial passageways, intraluminal valving devices for valving of transmyocardial passageways, intracardiac valving devices for valving of transmyocardial passageways, endogenous tissue valves for valving of transmyocardial passageways, and ancillary apparatus for use in conjunction therewith.

The present invention refers to the field of cardiac electrophysiology (EP) and, more specifically, to image-guided radio frequency ablation and pacemaker placement procedures. For those procedures, it is proposed to display the overlaid 2D navigation motions of an interventional tool intraoperatively obtained from the same projection angle for tracking navigation motions of an interventional tool during an image-guided intervention procedure while being navigated through a patient's bifurcated coronary vessel or cardiac chambers anatomy in order to guide e.g. a cardiovascular catheter to a target structure or lesion in a cardiac vessel segment of the patient's coronary venous tree or to a region of interest within the myocard. In such a way, a dynamically enriched 2D reconstruction of the patient's anatomy is obtained while moving the interventional instrument. By applying a cardiac and / or respiratory gating technique, it can be provided that the 2D live images are acquired during the same phases of the patient's cardiac and / or respiratory cycles. Compared to prior-art solutions which are based on a registration and fusion of image data independently acquired by two distinct imaging modalities, the accuracy of the two-dimensionally reconstructed anatomy is significantly enhanced.

Visualization of a medical procedure to be performed in a coronary vessel (such as a coronary sinus) of a patient is achieved by the steps of: identifying a coronary vessel for a procedure and placing a catheter within the coronary vessel. The coronary vessel is occluded at a site proximal to a distal end of the catheter. A contrast medium is injected into the coronary vessel through the catheter distal end for visualization of the procedure within the coronary vessel. Following the procedure, the contrast medium is removed through the catheter distal end and occlusion of the coronary vessel is discontinued.

Surgical methods and devices allow closed-chest surgery to be performed on a heart of a patient while the heart is beating. A region of the heart is stabilized by engaging a surface of the heart with a stabilizer without having to stop the heart. Motion of the target tissues is inhibited sufficiently to treat the target tissues with robotic surgical tools which move in response to inputs of a robotic system operator. A stabilizing surface of the stabilizer is coupled to a drive system to position the surface from outside the patient, preferably by actuators of the robotic servomechanism. Exemplary stabilizers includes a suture or other flexible tension member spanning between a pair of jointed bodies, allowing the member to occlude a coronary blood vessel and / or help stabilize the target region between the stabilizing surfaces.

The invention discloses an anchoring ball sac in a coronary stent, which comprises a hollow conduit; the outer wall of the front end of the conduit is provided with a first elastic ball sac; a liquid-injecting channel communicated with the first elastic bass sac is arranged in the conduit wall along the axial direction; and a plurality of bosses are arranged at the outer face of the first elastic ball sac. The using method comprises the steps of placing a guide wire into the far end of a coronary blood vessel by an already placed stent, and positioning the elastic ball sac at the front end of the conduit in the stent under the guide of the guide wire, wherein the outer end of the conduit is connected with a booster pump, and a developing agent is injected by the liquid-injecting channel to expand the elastic ball sac; and the bosses at the face of the bal sac can increase anchoring force, thus enhancing the ability of the coronary stent to pass through lesions such as torsion and calcification, better solving the technical problem that as the traditional coronary stent is poor in passing complicated lesions, the ball sac and the stent difficultly reach in place.

A method of treating the heart and other body tissues by injecting a compound comprised of microsphere encapsulated macromolecule therapeutic agents into the myocardium, such that the microsphere size inhibits capillary transport of the compound but may permit lymphatic transport of the compound, and the compound releases therapeutic agents upon degradation of the microsphere. The compounds may be used in a method of treating the coronary arteries in which lymphatic transportable therapeutic agents are injected into the myocardium at a location distal to a target site in the coronary artery, after which they are taken up by the lymphatic vessels and transported proximally relative to the coronary artery, and migrate from the lymphatic vessel to the coronary blood vessel.

The Chinese medicine adhesive film for preventing and treating coronary heart disease and angina pectoris consists of back lining material, medicine layer and protecting film. The medicine layer consists of skeleton supplementary material, effective Chinese medicine extractive and plasticizer; and the effective Chinese medicine extractive is ointment of extractive of Chuanxiong rhizome, sandalwood, nutagrass flatsedge rhizome, dalbergia wood, frankincense, kudzu vine root, etc. The Chinese medicine adhesive film is adhered to left chest for transdermal absorption to act on heart, and can dilate coronary blood vessel, improve blood flow of coronary blood vessel, improve heart function and prevent hidden coronary heart disease.

A method for surgically restoring a coronary artery having an atheroma, to more normal structure by making an arteriotomy incision over the length of the atheroma, extracting plaque, inserting stent into the coronary artery at the incision and closing the coronary artery over the stent with sutures. An extravascular drug delivery material is applied over the stent implantation site to inhibit thrombosis and smooth muscle cell proliferation.

A method of treating patients suffering from Alzheimer's disease by locating the areas of the brain affected by Alzheimer's disease and acting on the aforementioned areas of the patient's brain by laser energy through coronary blood vessels located adjacent to the aforementioned areas. The laser energy is delivered to the affected area through a set of microcatheters insertable sequentially and coaxially into each other and having diameters that allow insertion into distal coronary blood vessels.

The invention relates to a Chinese medicinal composition for treating broiler abdominal dropsy and a preparation method thereof. The Chinese medicinal composition is characterized by consisting of the following medicaments in part by weight: 48 to 52 parts of root of red-rooted salvia, 28 to 32 parts of szechuan lovage rhizome and 18 to 22 parts of tuckahoe. The preparation method comprises the following steps of: weighing the root of red-rooted salvia, the szechuan lovage rhizome and the tuckahoe serving as raw materials according to the weight ratio; crushing and screening to ensure that the particle diameter is between 60 and 200 meshes; and sub-packaging to obtain the finished product. The Chinese medicinal composition has the advantages that: the szechuan lovage rhizome and the root of red-rooted salvia in the prescription are common medicaments for activating blood circulation to dissipate blood stasis according to etiology and pathogenesis of the broiler abdominal dropsy; the modern pharmacological researches show that the szechuan lovage rhizome can relax lung blood vessels and reduce pulmonary artery pressure; and the root of red-rooted salvia and the szechuan lovage rhizome can also expand coronary vessels and increase blood supply of heart so as to obviously improve the function of the heart. By the method, the occurrence rate of the broiler abdominal dropsy can be greatly reduced in outdoor expansion tests under natural conditions.

The invention provides a three-dimensional reconstruction method and device for coronary blood vessels, electronic equipment and a storage medium, and the method comprises the steps: extracting an IVUS blood vessel inner contour based on an IVUS sequence; determining blood vessel geometric parameters based on CAG images at different angles at the same moment in a coronary artery angiography CAG sequence, the frame number corresponding to the IVUS at the key point position and the IVUS retracement rate, and performing three-dimensional blood vessel reconstruction based on the blood vessel geometric parameters; and positioning and orienting the IVUS sequence on the center line of the reconstructed three-dimensional blood vessel based on the inner contour of the IVUS blood vessel to obtain a fused three-dimensional coronary blood vessel model.

The invention provides a coronary image processing method and device. The method comprises the steps of: obtaining a coronary CTA image and a coronary DSA image sequence of a patient; carrying out three-dimensional reconstruction on the obtained coronary CTA image, obtaining a three-dimensional coronary image, and from the obtained three-dimensional coronary image, obtaining a coronary blood vessel CTA image central line and a simulated contrastographic image of a coronary blood vessel; from the obtained coronary DSA image sequence, determining a coronary DSA image and a coronary blood vessel DSA image central line which are most similar to the simulated contrastographic image; and carrying out registration on the coronary blood vessel DSA image central line and the coronary blood vessel CTA image central line, and obtaining a coronary fusion image of the simulated contrastographic image and the coronary DSA image. By adopting the coronary image processing method and device, a doctor is enabled to diagnose and treat the coronary artery disease patient according to the clear coronary image.

The invention discloses a dual-mode coronary blood vessel image three-dimensional fusion method and fusion system, and the method comprises the steps: obtaining a blood vessel image in an OCT mode, a blood vessel image in an IVUS mode, and a CAG image of a blood vessel through a blood vessel catheter; extracting a blood vessel three-dimensional skeleton in the CAG image according to the CAG image, and fitting according to the blood vessel three-dimensional skeleton to obtain a blood vessel center line; taking the center line of the blood vessel as a catheter withdrawing path, and respectively mapping the blood vessel image in the OCT mode and the blood vessel image in the IVUS mode to corresponding positions of the catheter withdrawing path of the blood vessel to complete image mapping; performing three-dimensional fusion of an OCT mode and an IVUS mode on the mapped image; the advantages of the three-dimensional CAG image in space, the strong tissue penetrating power of the IVUS and the high resolution of the OCT are fully exerted, more comprehensive information of the blood vessel wall and the coronary atherosclerotic plaque can be obtained, and therefore a more effective basis is provided for computer-assisted diagnosis and treatment of the coronary heart disease, evaluation of the interventional therapy effect and the like.

A method for producing paeonoside metabolic hormone-I by fermenting short Lactobacillus is carried out by inducing L.brevis AS 1.12 into culture medium with tomato juice 200g / L, protein peptone 7.5g / L, yeast paste 7.5g / L, glucose 10g / L, Tween-80 0.3 ml / L and pH=7.0-8.5, anaerobic culturing at 25-37 degree for 12-24 hrs, centrifugal collecting bacterial cells, washing by normal saline, centrifuging, dispersing obtained cells into buffer liquid of 0.05M phosphate, adding into substrate paeonoside or its analogs hydroxy-paeonoside or methyl-paeonoside or benzoyl-paeonoside or mixture of paeonoside and its analogs, converting at 30-40 degree for 2-24 hrs, extracting by ethyl acetate, drying concentrated extract to obtain concrete, chromatographying by silica-gel column to obtain final product. It's simple, cheap, efficient, fast and controllable and has friendly environment. It can be used for anti-inflammatory, stress ulcer, analgesic and antispasmodic, ecstatic coronary blood vessel, myocardial ischemia and platelet aggregation-inhibition.

A tissue grasping and clipping / stapling device includes a grasping jaw assembly for grasping tissue, and a fastener delivery and forming assembly adapted for applying a fastener to tissue grasped with the jaw assembly. The jaw assembly has a spring loaded closing mechanism to secure different thicknesses of tissue and the fastener feeding and applying mechanism is adaptable to different extents of closing of the jaw assembly. The device is particularly well suited for miniature clipping / stapling such as anastomosis of coronary blood vessels and the like.

The invention discloses a method for correcting coronary blood vessel models on the basis of implicit modeling technologies. Virtual stenting includes 1), inputted reconstructed coronary blood vesselmodels; 2), allowing a user to select two end points of a lesion blood vessel section required to be corrected, and acquiring the central axis of the lesion blood vessel section; 3), building tubularmodels according to section information of the central axis, a front end and a rear end; 4), blending the built tubular models F<S> and the original blood vessel models F<O> in a piecewise smooth manner by blending operators. The tubular models built at the step 3) represent virtual stents. Virtual bypass grafting includes 1), inputting the reconstructed coronary blood vessel models; 2), allowingthe user to select two connection points of the lesion blood vessel section required to be subjected to bypass grafting and certain control points so as to determine a central axis path for guiding bypass grafting tubular structures; 3), determining the sizes of the cross sections of the tubular structures and building tubular models according to the central axes of the tubular structures; 4), blending the built tubular models F and the original blood vessel models F<O> in a piecewise smooth manner by smooth piecewise polynomial blending operators. The tubular models built at the step 3) represent virtual bypass grafting.

The invention relates to a coronary artery calcification plaque detection method and device, and the method comprises the steps: carrying out the segmentation processing of a to-be-processed image, and determining a plurality of target regions of a first organ in the to-be-processed image; for any target area, determining a first gray threshold and a second gray threshold of the target area according to the gray information of the target area; respectively determining a suspected focus area and a pseudo focus area in the target area according to the first gray threshold and the second gray threshold of the target area; and determining the focus area of the first organ according to the suspected focus area and the pseudo focus area of each target area. According to the embodiment of the invention, omission of the calcified plaque at the small branch blood vessel of the coronary blood vessel in the to-be-processed image can be effectively reduced, the recall rate of the calcified plaque is improved, and the accuracy of identification of the calcified plaque can be remarkably improved.

The invention discloses a computer-aided surgery design system for coronary heart disease. The computer-aided surgery design system comprises a clinical examination module, a computer-aided module anda diagnosis and treatment module, which are sequentially connected, wherein the clinical examination module consists of a conventional inspection module 1 and a coronary angiography module 2 and is used for preliminarily judging whether the coronary heart disease or related heart diseases exist or not; the computer-aided module comprises a coronary vessel segmentation and reconstruction module 3and a vascular stenosis calculation module 4 and is used for performing segmentation and reconstruction on an angiography image and calculating coronary artery blood flow reserve fraction by applyinga computational fluid mechanics technology to quantitatively judge whether coronary artery interventional surgery treatment needs to be performed or not; and the diagnosis and treatment module consists of a doctor reexamination module 5 and an auxiliary surgery module 6, and the doctor reexamination module 5 feeds back a calculation result to enable the calculation result to be more credible. Thecomputer-aided surgery design system for the coronary heart disease can visually display a coronary artery anatomical structure and enable diagnosis of the coronary heart disease to be more visual andscientific.

The invention discloses a medicament for treating influenza and bad cold and a preparation method thereof. The medicament is prepared from green tea and crystal sugar according to a certain weight ratio. The medicament has the effect of stimulating high-level nervous centralis to excite spirit, can expand coronary blood vessels and peripheral blood vessels and loosen smooth muscles, is used for treating the influenza and the bad cold, and has quick curative effect and high cure rate.

The invention discloses medicinal liquor with the materials of animals and plants for kidney-reinforcing and health-improving, which is prepared by blending natural Chinese herbs and animals for the medical use. The active ingredients and the portions of each ingredient (gecko is compatible in pairs) are as follows: 1 portions to 6 portions of radix salivae miltiorrhizae, 3 portions to 12 portions of astragalus hoangtchy, 1 portions to 4 portions of medlar, 2 portions to 9 portions of polygonum, 1 portion to 12 portions of salvia miltiorrhiza, 2 portions to 8 portions of jujube kernel, 1 portion to 4 portions of semen amomi, 2 portions to 9 portions of herba epimedii, 2 portions to 10 portions of glue of tortoise plastron and 1 pair to 4 pairs of gecko. After being cleaned with water at the temperature of 20 DEG C to 25 DEG C and dried naturally, the ingredients are ground into fine powder together and packed into bags. The medicinal liquor of the invention has the effects of kidney-reinforcing and health-improving, heart blood nourishing, expansion of coronary blood vessel and blood pressure reducing, fat-reducing and heart strengthening, immunity enhancing, senility deferring, etc.

The invention relates to a health grape wine prepared by adding a suitable amount of ginkgo biloba leaf extract to grape wine. The health grape wine has a simple, convenient and practical manufacture method and low production cost, and the ginkgo biloba extract added to the grape wine can obviously improve the quality of the grape wine, increases the texture modification, the thickening and the stability of the grape wine and has lubricating grape wine taste and soft fragment. Meanwhile, the ginkgo biloba extract has the functions of expanding the coronary blood vessels and the cerebral blood vessels, increasing the coronary artery flow and the cerebral blood flow, improving the cardio-cerebral functions and improving symptoms and memory function generated by cerebral ischemia.

The invention provides a method and device for calculating vascular functional indexes, a computer storage medium and a processor. The method comprises the steps that a one-dimensional blood flow model of a target coronary blood vessel is obtained, and the one-dimensional blood flow model comprises unknown geometric information and unknown boundary conditions; unknown geometric information and unknown boundary conditions are solved, and a solved one-dimensional blood flow model is obtained; the solved one-dimensional blood flow model is adopted, and functional indexes of the target coronary blood vessels are obtained through calculation. The technical problems that in the prior art, a method for obtaining the blood flow characteristics through a three-dimensional flow equation is large in calculation amount and has high requirements for calculation resources are solved.

The invention discloses a coronary artery intravascular stent detection method and system based on an OCT image, and the method comprises the steps: obtaining an original OCT coronary artery image, and placing the image in a polar coordinate environment; the original OCT coronary blood vessel image is preprocessed, and preprocessing comprises the steps that the position of a catheter in the OCT coronary blood vessel image is detected, and a catheter area is removed; acquiring an image sequence formed in a guide wire withdrawing process, and forming three-dimensional reconstruction body data in a Cartesian coordinate environment; performing filtering enhancement on the preprocessed coronary blood vessel image by using multi-scale Frangi, and enhancing a stent shadow structure in the image; detecting the shadow position of the bracket for the enhanced image, and determining the position of the bracket; and detecting the position of the guide wire and the detected position of the stent by using the three-dimensional reconstruction volume data, segmenting a guide wire region, and removing the guide wire. According to the method, after multi-scale Frangi filtering enhancement is utilized, bracket shadow position detection and guide wire removal are carried out, the noise influence is reduced, and a high-fidelity image is obtained.

The present invention provides a method for quickly constructing a heart coronary vessel recognition data set, comprising: obtaining an original picture; marking blood vessels in the original picture to form a rough-labeled picture; performing pixel-level labeling on a very small amount of original pictures according to the rough-labeled picture. Form a finely labeled picture; change the finely labeled picture from a three-channel image to a single-channel image; binarize the single-channel image and store it as a binarized picture; use the binarized picture and its corresponding original picture as training data, Train the initial network to obtain the first network; input all the original pictures into the above-mentioned first network to obtain the binarized result map; generate pseudo-fine annotations based on the binarized result map and its corresponding rough-labeled pictures Pictures: Create a data set based on original pictures, finely labeled pictures, and pseudo-finely labeled pictures to train the network. This method greatly reduces the cost of manual labeling while ensuring the quality of the data set, and the training speed can be significantly improved.

The present invention relates to medical devices and particularly to a self-made membrane-contained stent auxiliary device. The self-made membrane-contained stent auxiliary device comprises a thin membrane fixing bearing base seat, a thin-membrane fixing panel is arranged in a middle part of the thin membrane fixing bearing base seat, a supporting clamp tool is arranged at each of a left end and aright end of the thin membrane fixing bearing base seat, each supporting clamp tool is provided with a stent fixing auxiliary rolling device, a stent is arranged between the left stent fixing auxiliary rolling device and the right stent fixing auxiliary rolling device, positioned at an upper end of the thin-membrane fixing panel and fixed by the stent fixing auxiliary rolling devices at two ends,and the stent and the stent fixing auxiliary rolling devices are connected on a central shaft in series; and the stent fixing auxiliary rolling devices are connected with the supporting clamp tools in a bearing type, and the stent fixing auxiliary rolling devices can rotate. The self-made membrane-contained stent auxiliary device improves a success rate of a self-made membrane-contained stent, isused for treating other arteries except coronary arteries, vein vessel perforation, arteriovenous fistula and aneurysm, increases timeliness of a rescue treatment, and improves a success rate of rescue of perforation and rupture of coronary blood vessels in coronary intervention operations.

Method and device for treatment of a heart after harvesting and before transplantation. The device comprises a container intended to comprise the heart; a first line for connection to an aorta of the heart; a fluid circuit comprising an oxygenator for oxygenating said fluid and a heater / cooler for regulating the temperature of said fluid; and a pump for perfusion of said fluid through the coronary blood vessels of the heart. The fluid comprises an oncotic agent exerting an oncotic pressure larger than about 30 mmHg and is cardioplegic by comprising a potassium concentration between 15 mM and 30 mM. A control device is arranged for controlling the pump to perform said perfusion intermittently, whereby the perfusion time is less than half of the cycle time. The perfusion is performed at a pressure of at least 15 mmHg and at least 15 mmHg lower than said oncotic pressure.

The invention relates to an image processing method and device, electronic equipment and a storage medium. The method comprises the following steps: acquiring a coronary artery blood vessel image and a heart image; performing image registration on the coronary blood vessel image and the heart image to obtain a corresponding relation of at least one homonymy image point in the coronary blood vessel image and the heart image; determining at least one first calcification region on the heart image; and determining a target calcification region having the corresponding relationship with a coronary blood vessel region in the coronary blood vessel image in the first calcification region. According to the embodiment of the invention, the accuracy of judging the target calcification region can be improved.

The invention discloses a formula and a processing process of a radix puerariae starch traditional Chinese medicine for preventing and treating diabetes, wherein the raw materials comprise, by mass, 13-23 parts of rehmannia glutinosa libosch, 10-20 parts of common yam rhizome, 5-10 parts of schisandra chinensis, 1-10 parts of ophiopogon japonicus, 5-15 parts of radix puerariae, 10-15 parts of clam powder, 10-20 parts of pumice stone, 15-20 parts of pollen, 1-5 parts of chicken's gizzard membrane, 5-10 parts of raw licorice root, 10-15 parts of cortex lycii, and 10-20 parts of raw rhizoma anemarrhenae. According to the present invention, the radix puerariae starch traditional Chinese medicine has effects of cardiac muscle oxygen consumption reducing, coronary blood flow increasing, angina pectoris relieving, anti-arrhythmia, immunity enhancing and the like, can well inhibit and prevent the symptoms of diabetic complication, and can reduce insulin resistance.