The invention discloses medicinal liquor with the materials of animals and plants for kidney-reinforcing and health-improving, which is prepared by blending natural Chinese herbs and animals for the medical use. The active ingredients and the portions of each ingredient (gecko is compatible in pairs) are as follows: 1 portions to 6 portions of radix salivae miltiorrhizae, 3 portions to 12 portions of astragalus hoangtchy, 1 portions to 4 portions of medlar, 2 portions to 9 portions of polygonum, 1 portion to 12 portions of salvia miltiorrhiza, 2 portions to 8 portions of jujube kernel, 1 portion to 4 portions of semen amomi, 2 portions to 9 portions of herba epimedii, 2 portions to 10 portions of glue of tortoise plastron and 1 pair to 4 pairs of gecko. After being cleaned with water at the temperature of 20 DEG C to 25 DEG C and dried naturally, the ingredients are ground into fine powder together and packed into bags. The medicinal liquor of the invention has the effects of kidney-reinforcing and health-improving, heart blood nourishing, expansion of coronary blood vessel and blood pressure reducing, fat-reducing and heart strengthening, immunity enhancing, senility deferring, etc.