57 results about "Vascular Stenosis" patented technology

The invention relates to the technical field of medical interventions, and discloses a difficult-to-layer composite woven balloon and a preparation method thereof, the difficult-to-layer composite woven balloon comprises an inner balloon and a fiber line structure woven on the outer surface of the inner balloon; the fiber thread structure is divided into warp threads and weft threads, the fiber threads extending in the diameter direction of the balloon are the warp threads, and the fiber threads extending in the axial direction of the balloon are the weft threads; the inner balloon is sequentially subjected to surface treatment, primer treatment, fiber weaving, surface treatment, surface sizing and surface curing treatment. The preparation process does not need complex special equipment, the material requirement is reasonable, the repeatability is high, the production difficulty and cost are reduced, convenience is provided for large-scale application of the material, and the material has extremely high practical value and popularization potential in medical scenes such as vascular stenosis dilation and calculus dilation pathway establishment.

The invention relates to the technical field of blood vessel stenosis grading, in particular to a blood vessel stenosis degree grading system based on coronary angiography images. The method comprises the following steps: dividing a vascular skeleton line of an angiography image into vascular segments based on a bifurcation point, and determining a stenosis point on the vascular segment according to the blood flow velocity difference of the vascular segment at the front edge position of a contrast agent in each frame of angiography image and a neighborhood angiography image; according to the blood vessel diameter difference between each bifurcation point and the other bifurcation points and the distance between the other bifurcation points and the main blood vessel section, a reference adaptation degree is obtained, a reference point of each bifurcation point is selected, and according to the blood flow speed difference between each bifurcation point and the branch blood vessel section of the reference point and the reference adaptation degree, narrow points in the bifurcation points are screened; and grading the blood vessel stenosis degree based on the blood vessel diameter of the stenosis point. The blood vessel skeleton line is divided into two conditions of the blood vessel segment and the bifurcation point to analyze the blood vessel physiological stenosis position, and the accuracy of positioning the pathological stenosis position in the coronary artery is improved.

The invention relates to the technical field of manufacturing of medical instruments, in particular to an intracranial controllable drug balloon dilatation catheter and a drug delivery method for a narrow area of a blood vessel. According to the intracranial controllable medicine balloon dilatation catheter, the inner-layer catheter body is arranged in the outer-layer catheter body in a sleeved mode and fixedly connected with the far end of the outer-layer catheter body; the balloon is assembled on the outer-layer tube body and is provided with a plurality of dosing holes along the circumferential direction; a medicine adhesion layer is compounded on the surface of the balloon section of the outer-layer tube body; the stress releasing pipe is connected to the end, close to the operation end, of the outer-layer pipe body. The Y-shaped tube base is connected to the end, away from the outer-layer tube body, of the stress releasing tube, one connector is connected with an injection device to inject medicine carriers into the balloon, and the other connector is used for a guide wire to penetrate through. When intracranial vascular stenosis is treated, directional drug release can be achieved by means of the drug delivery holes and the drug adhesion layer. The medicine is sprayed to the focus through the administration hole, the medicine is promoted to permeate into the middle layer of the blood vessel wall through the attaching force generated by the balloon expansion, the problems of non-uniform liquid medicine distribution, insufficient permeation and the like are effectively solved, and the local medicine concentration and the treatment effect are improved.

The application discloses a kind of iron agent enhanced whole body blood vessel multi-modal magnetic resonance imaging method, system, the method comprises: after target is divided into multiple scanning stations from head to foot, iron agent enhanced whole body blood vessel bright blood imaging is carried out;Automatic positioning whole body blood vessel stenosis and quantifying its stenosis degree, and output the scanning station and position range information of blood vessel stenosis region;Judge whether there is blood vessel stenosis region meeting condition;According to its spatial position information, guide MRI system examination bed to move for blood vessel stenosis region meeting condition, and carry out local black blood imaging with not less than the spatial range of blood vessel stenosis region;Blood vessel stenosis region exists in interval period and carries out local bright blood imaging to the scanning station, obtains blood vessel cavity structure image;Local bright blood imaging is registered with whole body blood vessel bright blood imaging, and the information transmission of blood vessel stenosis region is completed, and local inflammation imaging is carried out.The application realizes the multi-modal imaging evaluation of whole body blood vessel in clinically acceptable scanning time.

The invention relates to the technical field of image processing, in particular to a coronary artery angiography image blood vessel stenosis degree intelligent grading system which is used for obtaining angiography images of a coronary artery at multiple visual angles and the image quality score of each angiography image. Identifying a narrow point in each contrast image, and determining the single-view-angle narrow degree of the narrow point in each contrast image; matching the narrow points in the contrast images of different visual angles to obtain a matched narrow point of each narrow point in the contrast image of each visual angle in the contrast images of other visual angles; determining the final stenosis of each actual stenosis point in the coronary artery based on the single-view stenosis of each stenosis point, the single-view stenosis of the matched stenosis point of each stenosis point and the image quality score of each contrast image; and evaluating the stenosis level of each actual stenosis point based on the final stenosis degree of each actual stenosis point. The system can improve the accuracy, objectivity and reliability of narrowness measurement.

The invention discloses a nattokinase product for preventing and / or treating atherosclerosis and application of the nattokinase product. Cardiovascular diseases become the primary reason of human death, and the vascular plaque problem caused by atherosclerosis is always a difficult problem to be solved urgently. Blood vessel stenosis caused by plaques is a main cause of cerebral arterial thrombosis, and traditional medicines and operations face the problems of low compliance, side effect risk, indication limitation and the like. The invention provides nattokinase or a product thereof for high-risk groups with cardiovascular diseases, and the nattokinase or the product thereof is preferably in a non-drug form. As a precise nutrition intervention means, nattokinase is effective in plaque progress inhibition, unique in effect, safe to eat, convenient, easy to implement and wide in applicable crowd. The invention provides a new thought and method for management of vascular plaques and prevention and treatment of cardiovascular diseases.

The present application relates to the technical field of blood vessel stenosis grading, and particularly relates to a blood vessel stenosis degree grading system based on coronary angiography images. The present application divides the blood vessel skeleton line of the angiography images into blood vessel segments based on bifurcation points, determines the stenosis points on the blood vessel segments according to the blood flow velocity difference of the contrast agent front position of the blood vessel segments in each frame of the angiography images and its neighboring angiography images, obtains the reference adaptation degree according to the blood vessel diameter difference of each bifurcation point and the rest bifurcation points, and the distance between the rest bifurcation points and the main blood vessel segment, selects the reference point of each bifurcation point, screens the stenosis points in the bifurcation points according to the blood flow velocity difference of the branch blood vessel segments of each bifurcation point and its reference point and the reference adaptation degree, and grades the blood vessel stenosis degree based on the blood vessel diameter of the stenosis points. The present application divides the blood vessel skeleton line into blood vessel segments and bifurcation points to analyze the physiological stenosis position of the blood vessel, and improves the accuracy of positioning the pathological stenosis position in the coronary artery.

The invention discloses an intracranial posterior circulation vascular stenosis functional evaluation method and system, electronic equipment and a computer readable storage medium, and provides a vascular stenosis functional evaluation method based on bilateral blood flow conditions by fully considering the combined action of intracranial bilateral vertebral arteries on blood flow supply. The problem that in the prior art, only one side vertebral artery is considered to conduct vascular stenosis function evaluation, and the accuracy is low is solved, if only one side of the vertebral artery on the two sides of a patient has lesion, the compensation function of the opposite side healthy vertebral artery is neglected in the prior art, the influence of lesion on vascular function can be overestimated, and the vascular stenosis function evaluation accuracy is improved. According to the method, the bilateral vertebral arteries are coupled through the pressure drop constraint condition, and the intracranial posterior circulation vascular stenosis functional evaluation is comprehensively performed in combination with the condition of the basilar artery, so that the method is more accurate, and the output evaluation dimension is wider.

The application provides a kind of based on augmented reality navigation heart blood flow imaging system and navigation image generation method, it is related to biomedical optical imaging technical field, the system includes: laser speckle image acquisition unit according to electrocardiogram ECG signal determines acquisition window, and after the imaging focus is actively compensated based on real-time ranging result in the acquisition window, laser speckle image sequence of heart surface is collected;Navigation image generation unit quantifies the degree of stenosis of blood vessel according to blood flow index, and generates blood flow navigation image in combination with laser speckle image sequence;Navigation image projection unit projects blood flow navigation image to the corresponding blood vessel area of heart surface.The application provides based on augmented reality navigation heart blood flow imaging system and navigation image generation method, not only realizes high-fidelity, quantitative blood flow imaging and intuitive, in situ surgical navigation integration, also significantly improves the precision and safety of coronary artery bypass grafting and other heart surgery.

The invention discloses an anastomosis instrument for connecting multiple lymphatic vessels and blood vessels. The anastomosis instrument comprises a blood vessel connecting piece and a plurality of lymphatic connecting tubes. According to the integrated anastomosis instrument, the multiple lymphatic vessels can be connected to the lymphatic connecting tubes respectively through the arrangement of the integrated anastomosis instrument with the multiple lymphatic connecting tubes, and the lymphatic vessels are finally guided into the same vein blood vessel through the through holes; therefore, an efficient connection mode of multiple lymphatic vessels and a single blood vessel is realized, the surgical operation is greatly simplified, the surgical time is shortened, the surgical difficulty is greatly reduced, and the risks of postoperative bleeding, inflammation and vascular stenosis are reduced; in addition, due to the establishment of a plurality of drainage channels, the total drainage efficiency of lymph is effectively improved, and the device is more suitable for clinical conditions with large lymphatic load.

A stent assembly for implantation into a blood vessel includes an inlet zone having at least one inlet stent structure, the inlet stent structure having an inlet radial force configured to self-expand and at least substantially conform to a non-circular cross-sectional shape of the blood vessel. The stent assembly also includes a patent zone having at least one patent stent structure positioned distal to the inlet stent structure, the patent stent structure being self-expanding and having a patent radial force greater than the inlet radial force, the patent stent structure being configured to be positioned upstream from a stenosis along the blood vessel and coupled to the inlet stent structure such that the patent stent structure is configured to be positioned at the stenosis in the blood vessel.

The invention discloses a traditional Chinese medicine preparation for preventing postoperative vascular stenosis and occlusion and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine preparation for preventing postoperative vascular stenosis and occlusion is prepared from a multi-layer assembled amphiphilic polymer, a traditional Chinese medicine compound extract and curcumin, the multi-layer assembled amphiphilic polymer is used as a carrier, curcumin and a traditional Chinese medicine compound extract are effectively loaded in an encapsulation and adsorption mode, the drug loading capacity is improved, the drug concentration of a drug at a vascular focus part can be remarkably improved in a long-circulation, targeting and pH response release precise delivery mode, the bioavailability of the drug is improved, and the bioavailability of the drug is improved. Meanwhile, the precise delivery mode can also reduce the distribution of the medicine in normal tissues, so that the toxic and side effects are reduced, and the treatment safety is improved.

The present application provides a kind of vascular stenosis treatment device, it includes treatment component, the treatment component includes: balloon, the wall of the balloon has a plurality of first holes for liquid to pass, the balloon has unexpanded state and expanded state;Cover, the cover is covered outside the balloon and expands along with the balloon expansion, the cover has a plurality of second holes, when the balloon is in the expanded state, the aperture of the first hole is less than the aperture of the second hole.The vascular stenosis treatment device of the present application can realize accurate positioning, and the cover has a limiting effect on the liquid, so that the drug can be more uniformly and effectively act on the required position of the blood vessel wall, thereby improving the utilization rate of the drug, reducing the incidence of vascular restenosis, and improving the treatment effect.

This application provides a method, device, equipment, and medium for detecting vascular stenosis. The method includes: acquiring a binary image of a blood vessel diameter curve; determining a convex hull and multiple initial straight lines forming the convex hull in the binary image; determining multiple target straight lines from the initial straight lines, and performing line fitting on each target straight line to obtain multiple fitted straight lines and a fitted line equation corresponding to each fitted line; determining reference diameter information for each target center point in the binary image based on the fitted line equation corresponding to each fitted line; and determining at least one stenotic segment in the blood vessel and the stenosis rate corresponding to each stenotic segment using the equivalent diameter information of each target center point and the reference diameter information of each target center point. The detection method and device improve the accuracy and robustness of detecting vascular stenosis segments and stenosis rates.

This invention relates to the field of simulation training equipment technology, and discloses a whole-body vascular interventional simulation model and a blood circulation control system, including an integrated base in which a simulated blood vessel is disposed; and a blood circulation component, which includes a reservoir and a drive pump. The reservoir is connected to the inlet end of the simulated blood vessel through the drive pump. This invention solves the technical problems of existing vascular interventional simulation models being unable to simulate vascular compression scenarios and having insufficient linkage between blood circulation and compression states by coordinating the simulated blood vessel with blood circulation, compression, and air circuit components, combined with the overall coordinated control of the control unit. It can also realize multi-position vascular compression simulation, accurately reproduce clinical scenarios such as vascular stenosis and compression hemostasis. The overall structure is simple and highly realistic, effectively improving the completeness and pertinence of interventional training, and providing physicians with a training environment close to clinical reality.

An ultrasonic balloon catheter (1), which is introduced into the cardiovascular system and treats stenosis or occlusion of the heart or peripheral blood vessels, is provided with: a flexible catheter tube (11); the balloon (12) is made of an elastic material and provided with an expansion part (121) for expanding and contracting and neck parts (122) arranged at the two ends of the expansion part (121) respectively, the balloon (12) is fixedly arranged on the outer side of the catheter hose (11) through the neck parts (122), and the expansion part (121) and the neck parts (122) form an expansion space on the outer tube wall of the catheter hose (11) so that the fluid composition can be injected into the expansion space from the opening in the outer tube wall; and the ultrasonic probe (13) is arranged in the expansion part (121) of the balloon (12), is sleeved outside the inner pipe fitting (111) and at the opening in the outer pipe wall, and is used for emitting ultrasonic waves and inducing microbubbles in the fluid composition in the expansion space to generate a cavitation erosion effect.

A blood-clearing and lipid-lowering pill is composed of the following ingredients in the indicated weight ratios: Astragalus membranaceus 54-74, Salvia miltiorrhiza 54-74, Paeonia lactiflora 54-74, Carthamus tinctorius 33-53, Pheretima aspergillum 54-74, Hirudo medicinalis 33-53, Crataegus pinnatifida 54-74, Polygonum multiflorum 54-74, Cassia tora 54-74, Gastrodia elata 33-53, Uncaria rhynchophylla 54-74, Eucommia ulmoides 33-53, Achyranthes bidentata 54-74, Os draconis 54-74, Ostrea gigas 54-74, Prunella vulgaris 54-74, and Alisma plantago-aquatica 54-74. This invention can reduce blood viscosity to normal levels in a short period, allowing some patients with vascular stenosis exceeding 75% who require stents to avoid stent grafting, and enabling stroke patients to gradually recover their function.

The application provides a traditional Chinese medicine external application method for reducing the risk of fistula fibrosis in dialysis patients, relates to the technical field of clinical application of traditional Chinese medicine, is suitable for the prevention of autologous arteriovenous fistula fibrosis of maintenance hemodialysis patients, can effectively reduce the incidence of complications such as fistula peripheral tissue fibrosis and vascular stenosis, and prolongs the service life of the fistula. The drug stability and skin permeability are improved through optimization of adjuvants, and based on the grouping intervention of maintenance hemodialysis patients, the fistula blood flow and fibrosis improvement are evaluated in combination with color Doppler ultrasound. The application takes the principles of promoting blood circulation to remove blood stasis, dredging collaterals and resolving knots, and detoxification and swelling reduction as the therapeutic principles, prepares a fistula protection ointment by screening and optimizing a traditional Chinese medicine formula, realizes the effects of improving local microcirculation of the fistula, inhibiting fibrous tissue proliferation and reducing inflammatory reactions through external application intervention, thereby reducing the incidence of fistula fibrosis and related complications, prolonging the fistula patency time, simultaneously reducing the treatment cost, and improving the patient tolerance and life quality.

Objective tinnitus detection uses cycle-locked signal segmentation and coherent averaging. A tinnitus-related signal is acquired from a subject, and cycle markers corresponding to a repeating physiological cycle (e.g., cardiac cycle) are obtained. The acquired signal is segmented based on the cycle markers, aligned to a reference phase, and coherently averaged to enhance the signal-to-noise ratio of tinnitus-related components. In self-gating embodiments, cycle markers are derived from the acquired signal itself by detecting periodicity through autocorrelation or spectral analysis, allowing single-sensor operation. Spectral analysis of the enhanced waveform enables characterization of tinnitus etiology, including indicators of vascular stenosis. Comparison of pre-treatment and post-treatment measurements provides objective treatment efficacy monitoring. Systems implementing these methods range from clinical multi-modal configurations to simplified mobile single-sensor devices.

The invention discloses an application of a piperlongumine / ligustrazine derivative in vascular restenosis diseases, the derivative is PL-Lig-11, and the structural formula of the derivative is shown as a formula I. The invention further discloses a preparation method of the piperlongumine / ligustrazine derivative. The derivative effectively blocks the transformation of VSMC from a contraction phenotype to a proliferation phenotype through targeted inhibition of a key signal protein RhoGDI3, and significantly inhibits the abnormal proliferation and migration ability of VSMC, thereby fundamentally inhibiting the pathological process of NIH. Compared with parent compounds of piperlongumine and ligustrazine, the PL-Lig-11 shows higher anti-proliferative activity and higher selectivity, and the expected cytotoxicity is lower than that of clinically common chemotherapy drugs such as rapamycin and paclitaxel. The medicine can be used for preventing and treating vascular stenosis diseases caused by restenosis after PCI (percutaneous coronary intervention), hypertensive vascular remodeling, atherosclerotic plaque progress and other operations or injuries, and a candidate medicine with a novel action mechanism and good safety is provided for clinic.

The invention discloses a manufacturing method of a blood vessel puncture guiding and positioning card, and relates to the field of medical auxiliary instruments. According to the manufacturing method of the embodiment, the positioning card suitable for the patient can be manufactured based on the ultrasonic image data of the blood vessel of the patient, the subcutaneous invisible blood vessel three-dimensional path is converted into the entity continuous hollow guide groove in the card through the data processing and digital cutting technology, and the blood vessel positioning effect is improved. The card prepared by the method allows medical personnel to directly draw a continuous and accurate blood vessel trend guide line on the skin, so that the position of a puncture point is clear, and the needle inserting direction and the tangential angle of the blood vessel are more intuitively indicated; meanwhile, the blood vessel path is divided into a puncturable section and a penetration forbidding section according to the risk area data, it is ensured that the generated guide groove automatically avoids high-risk areas such as vascular stenosis and valves, the technical threshold of puncture operation is effectively lowered, and the puncture success rate and the blood vessel protection effect are improved.

The present invention relates to a device capable of wrapping the outer wall of a blood vessel, and a method for manufacturing the device. If the device for wrapping the outer wall of a blood vessel of the present invention is used, the outer wall of a blood vessel is wrapped, and, thereby, vortex generation can be significantly decreased by controlling abnormal expansion of the blood vessel which can occur due to the difference in the characteristics of blood vessels in a vein-artery graft model. The present invention saves a blood vessel from a low-oxygen state by promoting generation of new blood vessels on the outer wall of the blood vessel via a regenerative inflammatory response caused by the material of the device, and provides synergy effects such as prevention of vascular stenosis and reinforcement of an outer muscular layer by guiding venous muscular cells to the outside.

The invention provides a myocardial bridge detection method and device, equipment and a storage medium. The method comprises the following steps: acquiring continuous multi-frame cardiac blood vessel images covering at least one cardiac cycle; for each frame of cardiac blood vessel image, identifying a blood vessel stenosis position and a stenosis rate corresponding to each blood vessel stenosis position; extracting preset feature points of blood vessels in each frame of cardiac blood vessel image, performing position alignment on each frame of cardiac blood vessel image based on the feature points, and determining a cardiac phase direction corresponding to each frame of cardiac blood vessel image; for each blood vessel stenosis position, based on the stenosis rate of the blood vessel stenosis position in each frame of cardiac blood vessel image and the corresponding cardiac phase direction of each frame of cardiac blood vessel image, generating a dynamic curve of the stenosis rate of each blood vessel stenosis position changing along with the cardiac phase direction; and detecting whether each vascular stenosis position is a myocardial bridge based on each dynamic curve. According to the application, accurate detection of the myocardial bridge is realized by tracking the stenosis rate change of the blood vessel stenosis position in different heart periods.

The invention relates to the technical field of personal health risk assessment, in particular to a complication risk early warning and nursing method for an internal arteriovenous fistula patient, and the method comprises the steps: obtaining target tremor data and target noise data of a target internal arteriovenous fistula patient at each moment in a current time period; determining a current tremor distribution index, a current noise distribution index and a physiological performance abnormity degree; if the abnormal degree of the physiological performance is greater than a preset abnormal threshold value, acquiring an internal fistula ultrasonic image; according to the gray level distribution condition in the internal fistula area, the wall thickness change condition of the internal fistula wall and the diameter change condition of the internal fistula cavity, the overall structure characteristic value is determined; and determining the risk assessment auxiliary value of the vascular stenosis complication. According to the method, various data related to the risk of the vascular stenosis complication, such as tremor data, noise data and ultrasonic images, are comprehensively analyzed, so that the rationality of setting the auxiliary value for risk assessment of the vascular stenosis complication is improved, and the auxiliary effect is improved.

The invention relates to the technical field of image recognition and analysis, in particular to a DSA image-based blood vessel stenosis mode recognition and automatic quantitative analysis method, which comprises the following steps: S1, acquiring a DSA image sequence, positioning a blood vessel region, generating a blood vessel mask, dynamically adjusting an image enhancement parameter, performing time consistency calibration, and performing cross calibration on a calibrated image; generating a standardized DSA image sequence; s2, constructing a blood vessel topological structure chart, identifying blood vessel bifurcation nodes, analyzing a change curve of the blood vessel diameter along a center line, and identifying narrow candidate points at the bifurcation; performing mode classification, and outputting classified narrow position information; s3, calculating contrast agent passing time, and estimating blood flow velocity; measuring the diameter of the blood vessel and calculating fractional flow reserve; and calculating a comprehensive score of stenosis severity, and generating a quantitative analysis report of vascular stenosis. According to the method, a stenosis severity scoring system reflecting two dimensions of functions and anatomy is constructed and can be directly used for generating a structured analysis report.

The invention discloses a traditional Chinese medicine formula for preventing and treating body artery and blood vessel diseases, and relates to the technical field of pharmacy, in particular to a traditional Chinese medicine formula for preventing and treating body artery and blood vessel diseases, the traditional Chinese medicine composition is prepared from the following raw material medicines: 100g of radix puerariae, 100g of herba epimedii, 100g of herba leonuri, 50g of dioscorea panthaica, 50g of raw endothelium corneum gigeriae galli, 50g of fructus aurantii immaturus, 50g of rhizoma dioscoreae nipponicae, 50g of lumbricus and 50g of kapok leaves. Pharmacodynamic tests prove that compared with related traditional Chinese medicine prescriptions in the prior art, the traditional Chinese medicine composition can significantly reduce the intima-media thickness of blood vessels, reduce the area proportion of plaques, improve the blood vessel stenosis rate, and improve the curative effect. 0.05 in terms of prolonging thrombosis time, increasing microcirculation blood flow velocity, regulating blood lipid level (reducing total cholesterol, triglyceride and low-density lipoprotein cholesterol and increasing high-density lipoprotein cholesterol), protecting vascular endothelial function (increasing the content of vascular endothelial relaxation factor NO and reducing endothelin ET level) and the like, and the pharmaceutical composition is superior to the prior art group (Plt: 0.05) in terms of prolonging thrombosis time, increasing microcirculation blood flow velocity, regulating blood lipid level (reducing total cholesterol, triglyceride, low-density lipoprotein cholesterol and increasing high-density lipoprotein cholesterol).

The present application relates to the technical field of image data processing, in particular to a kind of blood vessel stenosis evaluation method based on cardiac angiography image, comprising: obtaining the suspected blood vessel contour region in the cardiac angiography image of patient, segmentation into several suspected blood vessel branch region, to filter out heart blood vessel branch region, according to the change of blood vessel width in heart blood vessel branch region, first type heart blood vessel stenosis region is segmented out, according to the similarity between the end points of the broken skeleton line between heart blood vessel branch region, determine the second type heart blood vessel stenosis region of broken place, linear transformation is carried out to the heart blood vessel stenosis region in cardiac angiography image, obtain cardiac angiography enhancement image, quantitative analysis is carried out to cardiac angiography enhancement image, obtain the stenosis degree of heart blood vessel.The present application improves the accuracy of blood vessel stenosis evaluation by contrast enhancement to unclear heart blood vessel stenosis region.

The utility model provides a blood flow controllable perfusion type balloon catheter. The blood flow controllable perfusion type balloon catheter comprises a catheter base, a balloon and a perfusion catheter connected between the catheter base and the balloon. The perfusion catheter is of a double-cavity structure and is composed of a guide wire cavity and a filling cavity which are independent of each other, and a blood perfusion hole is formed in the guide wire cavity. The perfusion catheter of a double-cavity structure is adopted, the perfusion catheter is composed of a guide wire cavity and a filling cavity which are independent of each other, the guide wire cavity is provided with a blood perfusion hole and a developing mark, the blood flow is controlled in cooperation with withdrawing of a guide wire, and blood flow can be kept to pass to a certain extent while it is guaranteed that the narrow part of the blood vessel is expanded in the sacculus filling state; complications caused by blood interruption in the operation of using the balloon are effectively avoided, and the operability and safety of the operation are improved.

The invention discloses a medical magnesium alloy intravascular stent and a preparation method thereof, and belongs to the technical field of medical biological materials and medical instruments. The stent comprises a magnesium alloy matrix, a hollow tubular structure and a surface modification layer, wherein the magnesium alloy matrix consists of the following components in percentage by mass: 90-98% of Mg, 1-5% of Zn, 0.1-1% of Ca, 0.5-3% of Y and unavoidable impurities; the pipe diameter of the hollow tubular structure is 2-5mm, the pipe wall thickness is 0.1-0.3 mm, the length is 8-30mm, and the hollow tubular structure is a rhombic grid (the side length is 0.5-1.5 mm); and the surface modification layer is a hydroxyapatite-chitosan composite coating with the thickness of 5-20 microns. The preparation method comprises the steps of magnesium alloy cast ingot preparation, pipe preparation, stent forming, surface modification and sterilization. The degradation period of the stent is 3-6 months (matched with the vascular repair period), the radial supporting force is larger than or equal to 8 N, the bending radius is smaller than or equal to 5 mm, the hydrogen generation amount is reduced by 40-60% compared with that of a pure magnesium stent, biocompatibility is good, adhesion and proliferation of vascular endothelial cells can be promoted, the preparation process is simple, cost is low, and the stent is suitable for treating vascular stenosis or clogging diseases.

The application provides an angiography image segmentation method and device, electronic equipment and readable storage medium. The method comprises the following steps: acquiring an angiography image, and inputting the angiography image into a pre-trained neural network model; after each layer of the neural network model performs convolution operation and activation operation on the input of the layer, the output of the layer is obtained through a blood vessel edge information enhancement operation of an edge and connected domain enhancement module; and the neural network model outputs a blood vessel contour segmentation result of the angiography image. By using the proposed edge and connected domain enhancement module and adding it to the neural network model layer by layer, the blood vessel edge information of different feature scales is fused, the segmentation result can better retain the edge information of the blood vessel contour and the connectivity between the contour regions, which is conducive to realizing an accurate and complete blood vessel contour segmentation result and helps to improve the accuracy and time efficiency of evaluating the blood vessel stenosis degree.