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103 results about "Vascular Stenosis" patented technology

Narrowing of the lumen of an artery or vein.

Cardiovascular disease layered early warning system

The invention relates to the technical field of health status assessment, in particular to a cardiovascular disease layered early warning system, which is characterized in that blood vessel compliance and pulse wave velocity are extracted, arterial dilation capacity is measured, blood vessel elasticity is calculated, blood perfusion distribution is detected, and abnormal vasoconstriction is classified on the basis of a hemodynamic state and a heart electrical activity state; in combination with the thickness of the blood vessel wall and the blood vessel stenosis rate, the plaque deposition condition is analyzed, the arteriosclerosis score is calculated, the thrombosis tendency is detected, the local blood flow blocking degree is quantified, the isolation forest algorithm is adopted, the blood flow dynamic change is calculated, the heart rhythm abnormality is analyzed, the acute vascular occlusion probability is measured, and the sudden heart rhythm abnormality risk is evaluated. And based on a gradient boosting tree algorithm, screening high-risk cases, matching medical intervention measures, setting a risk buffer mechanism, adjusting an individual health management strategy, and optimizing a cardiovascular risk hierarchical early warning system.
Owner:THE THIRD AFFILIATED HOSPITAL OF PLA NAVAL MEDICAL UNIVERSITY

Composite woven balloon not prone to layering and preparation method thereof

The invention relates to the technical field of medical interventions, and discloses a difficult-to-layer composite woven balloon and a preparation method thereof, the difficult-to-layer composite woven balloon comprises an inner balloon and a fiber line structure woven on the outer surface of the inner balloon; the fiber thread structure is divided into warp threads and weft threads, the fiber threads extending in the diameter direction of the balloon are the warp threads, and the fiber threads extending in the axial direction of the balloon are the weft threads; the inner balloon is sequentially subjected to surface treatment, primer treatment, fiber weaving, surface treatment, surface sizing and surface curing treatment. The preparation process does not need complex special equipment, the material requirement is reasonable, the repeatability is high, the production difficulty and cost are reduced, convenience is provided for large-scale application of the material, and the material has extremely high practical value and popularization potential in medical scenes such as vascular stenosis dilation and calculus dilation pathway establishment.
Owner:SUZHOU BEYO MEDICAL TECH CO LTD

Blood vessel stenosis degree grading system based on coronary angiography image

The invention relates to the technical field of blood vessel stenosis grading, in particular to a blood vessel stenosis degree grading system based on coronary angiography images. The method comprises the following steps: dividing a vascular skeleton line of an angiography image into vascular segments based on a bifurcation point, and determining a stenosis point on the vascular segment according to the blood flow velocity difference of the vascular segment at the front edge position of a contrast agent in each frame of angiography image and a neighborhood angiography image; according to the blood vessel diameter difference between each bifurcation point and the other bifurcation points and the distance between the other bifurcation points and the main blood vessel section, a reference adaptation degree is obtained, a reference point of each bifurcation point is selected, and according to the blood flow speed difference between each bifurcation point and the branch blood vessel section of the reference point and the reference adaptation degree, narrow points in the bifurcation points are screened; and grading the blood vessel stenosis degree based on the blood vessel diameter of the stenosis point. The blood vessel skeleton line is divided into two conditions of the blood vessel segment and the bifurcation point to analyze the blood vessel physiological stenosis position, and the accuracy of positioning the pathological stenosis position in the coronary artery is improved.
Owner:ORDNANCE IND HYGIENIC INST

Medical image curative effect evaluation system based on artificial intelligence

PendingCN120412926AImage enhancementImage analysisVascular diseaseVascular Medicine
The invention discloses a medical image curative effect evaluation system based on artificial intelligence, and the system is characterized in that an acquisition module obtains a clinical vascular medical image, builds an image database according to the clinical vascular medical image, and builds a high-resolution vascular three-dimensional image according to the image data in the image database; a positioning recognition module receives the blood vessel three-dimensional image and inputs the blood vessel three-dimensional image into a trained blood vessel positioning model, and the blood vessel positioning model automatically recognizes the blood vessel position and level in the blood vessel three-dimensional image; the evaluation module is used for cutting and calculating the blood vessel three-dimensional image according to the recognized blood vessel position and level and a preset size, and evaluating whether the lesion position and lesion type of the blood vessel with blood vessel stenosis, blood vessel dilatation and blood vessel thickening occur or not according to a calculation result; the technical problem that the prior art is difficult to accurately evaluate the curative effect of vascular diseases is solved.
Owner:HAINAN GIANT-STAR TECH CO LTD

Method and device for calculating blood flow at any position of blood vessel tree

The present invention relates to the technical field of medical image processing, and disclosed are a method and device for calculating blood flow at any position of a blood vessel tree. The method comprises: acquiring angiography image sequences, and performing structure extraction on images in the angiography image sequences to obtain two-dimensional blood vessel skeleton lines; performing three-dimensional reconstruction on the basis of the two-dimensional blood vessel skeleton lines to obtain a three-dimensional blood vessel model; determining a corresponding target blood vessel area on the basis of the three-dimensional blood vessel model, and calculating corresponding average blood flow in the target blood vessel area on the basis of transfer frame quantities corresponding to the angiography image sequences; reconstructing a reference blood vessel diameter on the basis of a corresponding blood vessel diameter in the target blood vessel area, and determining a blood vessel stenosis area on the basis of the blood vessel diameter and the reference blood vessel diameter; and calculating corresponding target blood flow at a target position in the target blood vessel area on the basis of the blood vessel stenosis area and the average blood flow. According to the present invention, blood flow at any position of blood vessels can be accurately calculated.
Owner:BEIJING INST OF TECH

Mobile balloon support catheter

ActiveUS12472333B2Balloon catheterGuide wiresEndovascular surgeryVascular Stenosis
The invention refers to endovascular catheters and methods useful to endovascular surgery. In particular, it refers to support catheters with balloons that are used for the placement or the forwarding of the guidewire through demanding tortuosity and important vascular stenoses in cases where the guidewire needs the best possible backup support of the catheter. This is achieved with the development of an endovascular support catheter (1) with a mobile balloon (22), which has the ability to move along the body of the catheter (2), at its distal part. The movement of the balloon (22) is achieved with the use of two mobile external rings (13) and (18), one inner wire circuit (23), (24), and one control handle (13) (17) which is found at the proximal end of the device (1). The mobile balloon allows the catheter to move inside the vessel even when it is inflated and basically anchored within the vessel.
Owner:SHUTTLE CATHETERS PC

Intracranial controllable drug balloon dilatation catheter and drug delivery method for narrow area of blood vessel

The invention relates to the technical field of manufacturing of medical instruments, in particular to an intracranial controllable drug balloon dilatation catheter and a drug delivery method for a narrow area of a blood vessel. According to the intracranial controllable medicine balloon dilatation catheter, the inner-layer catheter body is arranged in the outer-layer catheter body in a sleeved mode and fixedly connected with the far end of the outer-layer catheter body; the balloon is assembled on the outer-layer tube body and is provided with a plurality of dosing holes along the circumferential direction; a medicine adhesion layer is compounded on the surface of the balloon section of the outer-layer tube body; the stress releasing pipe is connected to the end, close to the operation end, of the outer-layer pipe body. The Y-shaped tube base is connected to the end, away from the outer-layer tube body, of the stress releasing tube, one connector is connected with an injection device to inject medicine carriers into the balloon, and the other connector is used for a guide wire to penetrate through. When intracranial vascular stenosis is treated, directional drug release can be achieved by means of the drug delivery holes and the drug adhesion layer. The medicine is sprayed to the focus through the administration hole, the medicine is promoted to permeate into the middle layer of the blood vessel wall through the attaching force generated by the balloon expansion, the problems of non-uniform liquid medicine distribution, insufficient permeation and the like are effectively solved, and the local medicine concentration and the treatment effect are improved.
Owner:NINGBO PEAK RUI MEDICAL TECHNOLOGY CO LTD

An iron agent enhanced whole body vascular multi-modal magnetic resonance imaging method and system

ActiveCN117958790BBlack bloodImaging study
The application discloses a kind of iron agent enhanced whole body blood vessel multi-modal magnetic resonance imaging method, system, the method comprises: after target is divided into multiple scanning stations from head to foot, iron agent enhanced whole body blood vessel bright blood imaging is carried out;Automatic positioning whole body blood vessel stenosis and quantifying its stenosis degree, and output the scanning station and position range information of blood vessel stenosis region;Judge whether there is blood vessel stenosis region meeting condition;According to its spatial position information, guide MRI system examination bed to move for blood vessel stenosis region meeting condition, and carry out local black blood imaging with not less than the spatial range of blood vessel stenosis region;Blood vessel stenosis region exists in interval period and carries out local bright blood imaging to the scanning station, obtains blood vessel cavity structure image;Local bright blood imaging is registered with whole body blood vessel bright blood imaging, and the information transmission of blood vessel stenosis region is completed, and local inflammation imaging is carried out.The application realizes the multi-modal imaging evaluation of whole body blood vessel in clinically acceptable scanning time.
Owner:SOUTHEAST UNIV

Balloon dilatation catheter capable of being filled in segmented mode

The invention provides a balloon dilatation catheter capable of being filled in a segmented mode, and belongs to the technical field of balloon dilatation catheters. The balloon dilatation catheter comprises a catheter body, an operating handle and a balloon body, the catheter body is used for being guided into a target blood vessel, and a filling channel extending in the axial direction is formed in the catheter body; the operating handle is arranged at the near end of the catheter body and is used for filling and discharging the filling medium into the filling channel; the balloon body is arranged at the position, close to the far end by a set distance, of the catheter body, a plurality of filling cavities are formed in the balloon body in the axial direction, a filling channel is communicated with the filling cavity at the farthest end, and a partition assembly is arranged between any two adjacent filling cavities and used for ensuring that the filling cavities are communicated with the filling cavity at the farthest end in the balloon body filling process. The plurality of filling chambers are sequentially filled from the far end to the near end; the balloon dilatation catheter is mainly used for solving the technical problems that in the prior art, a balloon dilatation catheter is integrally and synchronously filled and easily slips at a narrow blood vessel part, and a narrow area is difficult to accurately dilate.
Owner:THE FIRST PEOPLES HOSPITAL OF CHANGZHOU

Guiding catheter as well as preparation method and application thereof

The invention provides a guide catheter as well as a preparation method and application thereof, and the guide catheter comprises the following components in parts by weight: 100 parts of a matrix material; 5 to 10 parts of tripropyl citrate; 1 to 5 parts of polycaprolactone glycol; 5 to 10 parts of 1, 4-butanediol sulfate; 0.5 to 3 parts of a coupling agent; and 0.1-0.5% of an antioxidant. According to the guide catheter, the flexibility and lubricity of the base body are cooperatively regulated and controlled through all the materials, the rebound recovery rate of the catheter is increased, the deformation recovery capacity of the catheter when the catheter passes through a narrow or bent part of a blood vessel is greatly improved, creases or permanent bending is effectively avoided, and the controllability and safety in the pushing process are improved.
Owner:SHENZHEN MICROAPPROACH MEDICAL TECHNOLOGY CO LTD

An arteriovenous fistula vascular lining stent and methods of use thereof

The application discloses an arteriovenous fistula blood vessel lining support and a use method thereof, and the arteriovenous fistula blood vessel lining support has a three-way pipe structure; the axes of two passages in the three-way pipe structure are on a straight line to form a straight pipe, and the axis of the other passage has a variable included angle with the straight line formed by the axes of the first two passages to form a bifurcated pipe; the straight pipe and the bifurcated pipe jointly form a three-way shape of the support with an inner cavity and have optional additional structures near each port; the straight pipe is used for being implanted into an arterial blood vessel; and the bifurcated pipe is used for sleeving a venous blood vessel which needs to be connected. After the arteriovenous fistula blood vessel lining support is embedded, the occurrence of turbulent flow is effectively reduced, blood composition deposition is reduced, the probability of vascular hyperplasia and vascular stenosis is reduced, the arteriovenous fistula maturation time is shortened, and the use time of the fistula is prolonged.
Owner:NANJING UNIV

Intelligent grading system for coronary artery angiography image blood vessel stenosis degree

The invention relates to the technical field of image processing, in particular to a coronary artery angiography image blood vessel stenosis degree intelligent grading system which is used for obtaining angiography images of a coronary artery at multiple visual angles and the image quality score of each angiography image. Identifying a narrow point in each contrast image, and determining the single-view-angle narrow degree of the narrow point in each contrast image; matching the narrow points in the contrast images of different visual angles to obtain a matched narrow point of each narrow point in the contrast image of each visual angle in the contrast images of other visual angles; determining the final stenosis of each actual stenosis point in the coronary artery based on the single-view stenosis of each stenosis point, the single-view stenosis of the matched stenosis point of each stenosis point and the image quality score of each contrast image; and evaluating the stenosis level of each actual stenosis point based on the final stenosis degree of each actual stenosis point. The system can improve the accuracy, objectivity and reliability of narrowness measurement.
Owner:SHUNTONG INFORMATION TECH (DALIAN) CO LTD

Nattokinase product for preventing and / or treating atherosclerosis and application thereof

The invention discloses a nattokinase product for preventing and / or treating atherosclerosis and application of the nattokinase product. Cardiovascular diseases become the primary reason of human death, and the vascular plaque problem caused by atherosclerosis is always a difficult problem to be solved urgently. Blood vessel stenosis caused by plaques is a main cause of cerebral arterial thrombosis, and traditional medicines and operations face the problems of low compliance, side effect risk, indication limitation and the like. The invention provides nattokinase or a product thereof for high-risk groups with cardiovascular diseases, and the nattokinase or the product thereof is preferably in a non-drug form. As a precise nutrition intervention means, nattokinase is effective in plaque progress inhibition, unique in effect, safe to eat, convenient, easy to implement and wide in applicable crowd. The invention provides a new thought and method for management of vascular plaques and prevention and treatment of cardiovascular diseases.
Owner:RISHENGYAN LIFE SCIENCES (ZHEJIANG) CO LTD

Coronary angiogram-based stenosis severity grading system

The present application relates to the technical field of blood vessel stenosis grading, and particularly relates to a blood vessel stenosis degree grading system based on coronary angiography images. The present application divides the blood vessel skeleton line of the angiography images into blood vessel segments based on bifurcation points, determines the stenosis points on the blood vessel segments according to the blood flow velocity difference of the contrast agent front position of the blood vessel segments in each frame of the angiography images and its neighboring angiography images, obtains the reference adaptation degree according to the blood vessel diameter difference of each bifurcation point and the rest bifurcation points, and the distance between the rest bifurcation points and the main blood vessel segment, selects the reference point of each bifurcation point, screens the stenosis points in the bifurcation points according to the blood flow velocity difference of the branch blood vessel segments of each bifurcation point and its reference point and the reference adaptation degree, and grades the blood vessel stenosis degree based on the blood vessel diameter of the stenosis points. The present application divides the blood vessel skeleton line into blood vessel segments and bifurcation points to analyze the physiological stenosis position of the blood vessel, and improves the accuracy of positioning the pathological stenosis position in the coronary artery.
Owner:ORDNANCE IND HYGIENIC INST

Functional evaluation method and system for intracranial posterior circulation vascular stenosis, electronic equipment and computer readable storage medium

ActiveCN121416106AMedical simulationImage analysisLeft vertebral arteryIntracranial Artery
The invention discloses an intracranial posterior circulation vascular stenosis functional evaluation method and system, electronic equipment and a computer readable storage medium, and provides a vascular stenosis functional evaluation method based on bilateral blood flow conditions by fully considering the combined action of intracranial bilateral vertebral arteries on blood flow supply. The problem that in the prior art, only one side vertebral artery is considered to conduct vascular stenosis function evaluation, and the accuracy is low is solved, if only one side of the vertebral artery on the two sides of a patient has lesion, the compensation function of the opposite side healthy vertebral artery is neglected in the prior art, the influence of lesion on vascular function can be overestimated, and the vascular stenosis function evaluation accuracy is improved. According to the method, the bilateral vertebral arteries are coupled through the pressure drop constraint condition, and the intracranial posterior circulation vascular stenosis functional evaluation is comprehensively performed in combination with the condition of the basilar artery, so that the method is more accurate, and the output evaluation dimension is wider.
Owner:HANGZHOU ARTERYFLOW TECH CO LTD

Method and device for analyzing angiographic images

Embodiments of the present invention relate to a method and apparatus for analyzing angiographic images. The method comprises: acquiring an angiographic image; detecting vascular stenosis sites and using a sub-image of the detected stenosis sites as a first image; performing binarization and image noise reduction to generate a first binary image; performing vessel identification to generate a vascular image; extracting a centerline from the vascular image in the first binary image without changing the topological properties of the vascular image to generate a first centerline; sorting pixels on the first centerline to generate a first pixel sequence; measuring the vascular diameter at each first pixel to generate a first diameter; identifying the vascular stenosis rate at each first pixel to generate a corresponding first stenosis rate; and returning the first pixel sequence, first diameter sequence, and first stenosis rate sequence as vascular stenosis analysis data for the angiographic image. The present invention can improve analysis accuracy.
Owner:LEPU MEDICAL TECH (BEIJING) CO LTD

Cardiac blood flow imaging system based on augmented reality navigation and navigation image generation method

PendingCN122398463AEcg signalCardiac surface
The application provides a kind of based on augmented reality navigation heart blood flow imaging system and navigation image generation method, it is related to biomedical optical imaging technical field, the system includes: laser speckle image acquisition unit according to electrocardiogram ECG signal determines acquisition window, and after the imaging focus is actively compensated based on real-time ranging result in the acquisition window, laser speckle image sequence of heart surface is collected;Navigation image generation unit quantifies the degree of stenosis of blood vessel according to blood flow index, and generates blood flow navigation image in combination with laser speckle image sequence;Navigation image projection unit projects blood flow navigation image to the corresponding blood vessel area of heart surface.The application provides based on augmented reality navigation heart blood flow imaging system and navigation image generation method, not only realizes high-fidelity, quantitative blood flow imaging and intuitive, in situ surgical navigation integration, also significantly improves the precision and safety of coronary artery bypass grafting and other heart surgery.
Owner:TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI

Anastomosis instrument for connecting multiple lymphatic vessels and blood vessels

The invention discloses an anastomosis instrument for connecting multiple lymphatic vessels and blood vessels. The anastomosis instrument comprises a blood vessel connecting piece and a plurality of lymphatic connecting tubes. According to the integrated anastomosis instrument, the multiple lymphatic vessels can be connected to the lymphatic connecting tubes respectively through the arrangement of the integrated anastomosis instrument with the multiple lymphatic connecting tubes, and the lymphatic vessels are finally guided into the same vein blood vessel through the through holes; therefore, an efficient connection mode of multiple lymphatic vessels and a single blood vessel is realized, the surgical operation is greatly simplified, the surgical time is shortened, the surgical difficulty is greatly reduced, and the risks of postoperative bleeding, inflammation and vascular stenosis are reduced; in addition, due to the establishment of a plurality of drainage channels, the total drainage efficiency of lymph is effectively improved, and the device is more suitable for clinical conditions with large lymphatic load.
Owner:SHINEYARD MEDICAL DEVICE CO LTD

Stent System

A stent assembly for implantation into a blood vessel includes an inlet zone having at least one inlet stent structure, the inlet stent structure having an inlet radial force configured to self-expand and at least substantially conform to a non-circular cross-sectional shape of the blood vessel. The stent assembly also includes a patent zone having at least one patent stent structure positioned distal to the inlet stent structure, the patent stent structure being self-expanding and having a patent radial force greater than the inlet radial force, the patent stent structure being configured to be positioned upstream from a stenosis along the blood vessel and coupled to the inlet stent structure such that the patent stent structure is configured to be positioned at the stenosis in the blood vessel.
Owner:RGT UNIV OF CALIFORNIA +1

Cerebral stroke management method and device, equipment and storage medium

The embodiment of the invention relates to a cerebral apoplexy management method and device, equipment and a storage medium, and the method comprises the steps: segmenting a fundus blood vessel region from a fundus photo, and carrying out the recognition based on the fundus photo to obtain a first eye recognition result; calculating feature parameters of the fundus blood vessels based on the fundus blood vessel region; a retinal nerve layered image is obtained based on fundus OCT, a fundus lesion area is segmented from fundus OCTA, and a second eye recognition result is obtained based on fundus OCTA recognition; calculating feature parameters of retina nerve layering based on the retina nerve layering image, and calculating feature parameters of fundus lesion based on the fundus lesion area; and performing chronic disease information identification and / or cerebral vascular stenosis degree identification based on the feature parameters of the fundus blood vessels and the first eye identification result, and identifying the cerebral vascular stenosis degree based on the feature parameters of the retinal nerve layering, the feature parameters of the fundus lesions and the second eye identification result. Management of intelligent screening, risk prediction, progress monitoring and / or prognosis evaluation of the stroke population is carried out.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Traditional Chinese medicine preparation for preventing postoperative vascular stenosis and occlusion and preparation method thereof

The invention discloses a traditional Chinese medicine preparation for preventing postoperative vascular stenosis and occlusion and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine preparation for preventing postoperative vascular stenosis and occlusion is prepared from a multi-layer assembled amphiphilic polymer, a traditional Chinese medicine compound extract and curcumin, the multi-layer assembled amphiphilic polymer is used as a carrier, curcumin and a traditional Chinese medicine compound extract are effectively loaded in an encapsulation and adsorption mode, the drug loading capacity is improved, the drug concentration of a drug at a vascular focus part can be remarkably improved in a long-circulation, targeting and pH response release precise delivery mode, the bioavailability of the drug is improved, and the bioavailability of the drug is improved. Meanwhile, the precise delivery mode can also reduce the distribution of the medicine in normal tissues, so that the toxic and side effects are reduced, and the treatment safety is improved.
Owner:DONGFANG HOSPITAL AFFILIATED TO TONGJI UNIV JIAOZHOU HOSPITAL +1

A guide catheter and its preparation method and application

The present invention provides a guide catheter, a preparation method, and applications thereof. The guide catheter comprises the following components, measured by weight: 100 parts of a base material; 5-10 parts of tripropyl citrate; 1-5 parts of polycaprolactone diol; 5-10 parts of 1,4-butanediol sulfate; 0.5-3 parts of a coupling agent; and 0.1-0.5 parts of an antioxidant. The guide catheter of the present invention utilizes the synergistic effects of various materials to regulate the flexibility and lubricity of the base material, thereby improving the catheter's rebound recovery rate and significantly enhancing its ability to recover from deformation when navigating narrow or curved blood vessels. This effectively prevents creases or permanent bends, and enhances maneuverability and safety during delivery.
Owner:SHENZHEN MICROAPPROACH MEDICAL TECHNOLOGY CO LTD

An image synthesis method based on transformer-GAN model and its application

The present invention relates to an image synthesis method and application based on a transformer-GAN model, and relates to the field of artificial intelligence image generation. The method comprises: S1, image acquisition: acquiring multiple imaging sequences; S2, data processing: using the medical image registration module in the 3D Slicer software to perform image registration on the imaging sequences, completing image cropping and brightness unification operations, and obtaining an image pair data set; S3, model training: constructing a multi-head self-attention generative adversarial network model, and deploying it on a server, training the image pair data set to obtain an optimal training model; S4, image synthesis: using the optimally trained multi-head self-attention generative adversarial network model to perform image synthesis. The application is the application in the identification of vascular stenosis and plaques in intracranial atherosclerotic diseases. The present invention provides a more convenient, low-cost, and high-recognition image synthesis method for the treatment of intracranial atherosclerotic diseases based on an image transformation model.
Owner:WUHAN UNIV

A vascular stenosis treatment device

The present application provides a kind of vascular stenosis treatment device, it includes treatment component, the treatment component includes: balloon, the wall of the balloon has a plurality of first holes for liquid to pass, the balloon has unexpanded state and expanded state;Cover, the cover is covered outside the balloon and expands along with the balloon expansion, the cover has a plurality of second holes, when the balloon is in the expanded state, the aperture of the first hole is less than the aperture of the second hole.The vascular stenosis treatment device of the present application can realize accurate positioning, and the cover has a limiting effect on the liquid, so that the drug can be more uniformly and effectively act on the required position of the blood vessel wall, thereby improving the utilization rate of the drug, reducing the incidence of vascular restenosis, and improving the treatment effect.
Owner:SUZHOU TIANHONGSHENGJIE MEDICAL INSTR CO LTD

Ultrasonic controlled-release drug balloon catheter and application thereof

The invention discloses an ultrasonic controlled-release drug balloon catheter which comprises a balloon with the outer surface coated with a drug coating and a catheter penetrating through the balloon, and the drug coating comprises a drug carrying layer, a hydrophilic layer located between the outer surface of the balloon and the drug carrying layer and an ultrasonic response layer located on the outer surface of the drug carrying layer; the ultrasonic response layer comprises the following components: at least one of PDMS (Polydimethylsiloxane), P (AAA) and P (NIPAM-co-AM); and an ultrasonic transducer is arranged on the catheter in the balloon. According to the ultrasonic controlled-release medicine balloon catheter, a'sandwich 'design of'hydrophilic bottom layer-medicine carrying layer-ultrasonic response layer' is adopted for the medicine coating on the surface of the balloon, and ultrasonic transducers with two or more frequencies are further arranged on the catheter in the balloon, so that the loss of the medicine coating in the conveying process can be avoided; transfer of the medicine from the balloon to the blood vessel at the treatment position is increased, the medicine can deeply permeate into the vascular tissue, vascular stenosis can be effectively inhibited for a long time, and the medicine utilization rate is effectively increased.
Owner:BROSMED MEDICAL CO LTD

A method, device, equipment and medium for detecting a vascular stenosis segment

This application provides a method, device, equipment, and medium for detecting vascular stenosis. The method includes: acquiring a binary image of a blood vessel diameter curve; determining a convex hull and multiple initial straight lines forming the convex hull in the binary image; determining multiple target straight lines from the initial straight lines, and performing line fitting on each target straight line to obtain multiple fitted straight lines and a fitted line equation corresponding to each fitted line; determining reference diameter information for each target center point in the binary image based on the fitted line equation corresponding to each fitted line; and determining at least one stenotic segment in the blood vessel and the stenosis rate corresponding to each stenotic segment using the equivalent diameter information of each target center point and the reference diameter information of each target center point. The detection method and device improve the accuracy and robustness of detecting vascular stenosis segments and stenosis rates.
Owner:SHENZHEN RAYSIGHT INTELLIGENT MEDICAL TECH CO LTD

A whole-body vascular interventional simulation model and blood circulation control system

This invention relates to the field of simulation training equipment technology, and discloses a whole-body vascular interventional simulation model and a blood circulation control system, including an integrated base in which a simulated blood vessel is disposed; and a blood circulation component, which includes a reservoir and a drive pump. The reservoir is connected to the inlet end of the simulated blood vessel through the drive pump. This invention solves the technical problems of existing vascular interventional simulation models being unable to simulate vascular compression scenarios and having insufficient linkage between blood circulation and compression states by coordinating the simulated blood vessel with blood circulation, compression, and air circuit components, combined with the overall coordinated control of the control unit. It can also realize multi-position vascular compression simulation, accurately reproduce clinical scenarios such as vascular stenosis and compression hemostasis. The overall structure is simple and highly realistic, effectively improving the completeness and pertinence of interventional training, and providing physicians with a training environment close to clinical reality.
Owner:MEI HOSPITAL UNIV OF CHINESE ACAD OF SCI

Visual analysis method for body surface detection of vascular stenosis

The invention discloses a visual analysis method for detecting vascular stenosis on a body surface. The method specifically comprises the following steps: S1, synchronously collecting a high-frequency turbulence vibration signal and a blood flow volume waveform signal caused by the vascular stenosis in a target vascular area on the body surface through a piezoelectric sensor array and a PPG sensor array; s2, sequentially performing charge amplification and 0.5-100Hz low-pass filtering on the vibration signal, and extracting gt through fast Fourier transform; the turbulence energy intensity at the frequency band of 50 Hz is detected, transimpedance amplification is conducted on the blood flow volume waveform signals in sequence, and blood flow waveform parameters are calculated; s3, position information of all sensors in the piezoelectric sensor array and the PPG sensor array is obtained, and turbulence energy intensity information and blood flow waveform parameter information are fused to construct a multi-dimensional feature vector; and S4, inputting the multi-dimensional feature vectors into a pre-trained AI analysis model, and respectively outputting boundary coordinates, stenosis severity level and local blood flow velocity estimation values of the stenosis high-risk region.
Owner:ZHONGSHAN HOSPITAL AFFILIATED TO FUDAN UNIV XIAMEN HOSPITAL

Multifunctional catheter for treating vascular stenosis

The invention relates to the technical field of multifunctional catheters, in particular to a multifunctional catheter for treating vascular stenosis. The tubular body defines a cavity, the cavity comprises a first cavity and a second cavity, the cross sectional areas of the first cavity and the second cavity are small and large, and the first cavity and the second cavity extend from the near end of the tubular body to the far end of the tubular body and then are communicated with the outside; the first connecting tube and the second connecting tube are located at the near end of the tubular body, one end of the first connecting tube is connected with the input end of the first cavity, the other end of the first connecting tube is used for being connected with a contrast agent injection device, and the second connecting tube is connected with the input end of the second cavity and serves as a guide opening for conveying interventional instruments; the first cavity and the second cavity are formed in the tubular body, so that seamless switching between a radiography step and an interventional therapy step can be realized; keeping the catheter in situ in the whole diagnosis and treatment period; the multifunctional cavity is compositely utilized, so that the operation time is greatly saved, and the problem that blood vessels are easily damaged due to repeated replacement of catheters is solved.
Owner:HANGZHOU XIAOSHAN DISTRICT SECOND PEOPLES HOSPITAL

Ultrasonic balloon catheter

An ultrasonic balloon catheter (1), which is introduced into the cardiovascular system and treats stenosis or occlusion of the heart or peripheral blood vessels, is provided with: a flexible catheter tube (11); the balloon (12) is made of an elastic material and provided with an expansion part (121) for expanding and contracting and neck parts (122) arranged at the two ends of the expansion part (121) respectively, the balloon (12) is fixedly arranged on the outer side of the catheter hose (11) through the neck parts (122), and the expansion part (121) and the neck parts (122) form an expansion space on the outer tube wall of the catheter hose (11) so that the fluid composition can be injected into the expansion space from the opening in the outer tube wall; and the ultrasonic probe (13) is arranged in the expansion part (121) of the balloon (12), is sleeved outside the inner pipe fitting (111) and at the opening in the outer pipe wall, and is used for emitting ultrasonic waves and inducing microbubbles in the fluid composition in the expansion space to generate a cavitation erosion effect.
Owner:叶秩光