46 results about "Vascular body" patented technology

A method and system for analyzing tubular structures, such as vascular bodies, with respect to their geometrical properties and mechanical loading conditions is disclosed. To this end, geometrical and structural models of vascular bodies are generated from standard sets of image data. The method or system works automatically and the tubular structure is analyzed within clinical relevant times by users without engineering background. Most critical in that sense is the integration of novel volume meshing and 3D segmentation techniques. The derived geometrical and structural models distinguish between structural relevant types of tissue, e.g., for abdominal aortic aneurysms the vessel wall and the intra-luminal thrombus are considered separately. The structural investigation of the vascular body is based on a detailed nonlinear Finite Element analysis. Here, the derived geometrical model, in-vivo boundary/loading conditions and finite deformation constitutive descriptions of the vascular tissues render the structural biomechanical problem. Different visualization concepts are provided and allow an efficient and detailed investigation of the derived geometrical and mechanical data. In addition, this information is pooled and statistical properties, derived from it, can be used to analyze vascular bodies of interest.

The present invention provides compositions and methods for treating or preventing diseases associated with vascular and non-vascular body passageways, the method comprising the step of delivering to a body passageway a therapeutic agent delivered locally through a polymer matrix from an implanted stent or other structure.

A system for the treatment of lower extremity arterial chronic total occlusion (CTO) incorporates remote access of the guide-wire, at least one specifically shaped catheter, and a wire-capture dilation balloon catheter. A capture balloon catheter serves to capture the wire used to traverse the CTO. The capture balloon has a lumen with two axial openings and a radial opening. The capture balloon enters the vascular body from a first opening along a first guide-wire until the balloon is adjacent the CTO. A second guide-wire is advanced from a second opening in the vascular body that is located on an opposite side of the CTO. After the first guide-wire is removed, the second guide-wire is advanced through the funnel-shaped opening in the balloon, then through the radial opening of the lumen and through the lumen so as to advance out of the first opening of the vascular body. A conventional treatment balloon can then be advanced on the second guide-wire to the CTO for treatment.

The invention discloses a blood collection tube uncovering and covering all-in-one machine and a blood collection tube rack of the blood collection tube uncovering and covering all-in-one machine. In operation, blood collection tube bodies and blood collection tube caps of vacuum blood collection tubes are respectively clamped through a blood collection tube body clamping device and a blood collection tube cap clamping device, wherein the blood collection tube body clamping device controls the separation of a plurality of abreast gripper components through a first motor, and therefore the vacuum blood collection tubes can be placed in the gripper components, and the closing of the gripper components is controlled to guarantee that the blood collection tube bodies of the vacuum blood collection tubes are stably clamped; and meanwhile, the blood collection tube cap clamping device controls a third worm gear and third worm component to work through a third motor so as to achieve the opening and closing of the blood collection tube caps of the vacuum blood collection tubes. Through the structural design, the blood collection tube uncovering and covering all-in-one machine and the blood collection tube rack of the blood collection tube uncovering and covering all-in-one machine can reduce biohazards, improve safety production capability, reduce manpower cost, improve labor efficiency, promote the automation, the informatization and the intelligentization levels of medical laboratories, reduce resource cost, and improve work efficiency.

The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve exposing a portion of a tissue of the subject in vivo to a magnetic field and RF pulse from the device to excite hydrogen nuclei of water within the tissue portion, and measuring a relaxation parameter of the hydrogen nuclei in the tissue portion, the relaxation parameter being a quantitative measure of the hydration state or vascular volume of the subject as a whole. The invention also features devices and computer-readable storage media for per forming the methods of the invention.

The invention provides a composite aortic arch reconstruction system and a using method thereof. The system comprises a quadrifurcation vascular prosthesis and a cross arch covered stent; the vascularprosthesis comprises a vascular body, an arch upper branch communicated with the vascular body and a perfusion branch, the arch upper branch is sequentially divided into an anonyma branch, a left common carotid branch and a left collarbone lower branch, and blood vessel lumina are communicated with each other. The cross arch covered stent comprises an inner layer metal stent and an outer layer vascular cover, and conical and preflex designs which more conform to the physiological structure of an aorta of a human body are adopted. When an aortic arch surgery is carried out, deep hypothermic circulatory arrest can be avoided by means of the system to reduce the difficulties of vascular anatomy and vascular anastomosis, shorten the surgical operating time and improve the success rate of thesurgery.

Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

The present invention provides compositions and methods for treating or preventing diseases associated with vascular and non-vascular body passageways, the method comprising the step of delivering to a body passageway a therapeutic agent delivered locally through a polymer matrix from an implanted stent or other structure.

The invention discloses a method for quickly establishing an intracranial blood vessel simulation three-dimensional model based on transfer learning. The method comprises the following steps: collecting a bright blood image group and an enhanced black blood image group of an intracranial blood vessel part; preprocessing each bright blood image and the corresponding enhanced black blood image to obtain a first bright blood image and a first black blood image; performing image registration on the first bright blood image by using mutual information based on Gaussian distribution sampling and a registration method of an image pyramid; utilizing a maximum intensity projection method to obtain MIP images in all directions from the registered bright blood image groups; taking the MIP image as atarget domain, taking the fundus blood vessel image as a source domain, and obtaining a two-dimensional blood vessel segmentation image by using a transfer learning method; performing back projectionsynthesis on the two-dimensional blood vessel segmentation images in the three directions to obtain first three-dimensional blood vessel body data; and obtaining an intracranial blood vessel simulation three-dimensional model by utilizing the second three-dimensional blood vessel body data corresponding to the registered bright blood image group. According to the method, the whole state of the intracranial blood vessel can be simply, conveniently, quickly and visually obtained clinically.

The invention discloses an in-vitro stress culture device for a blood vessel, a culture system and a culture method. The device is characterized in that two sides of a culture tank are coaxially provided with connecting pieces in which first fixed parts are coaxially arranged, fasteners are coaxially fixed outside the connecting pieces and are internally and coaxially provided with second fixed parts, and the first fixed parts and the second fixed parts are internally, respectively and coaxially provided with a third through hole and a fourth through hole; sealing rings are arranged between the first fixed parts and the second fixed parts; blood vessel connecting pipes extend into the culture tank after passing through the fourth through holes, the sealing rings and the third through holes. The device is capable of improving the coaxiality of the blood vessel and the blood vessel connecting pipes and good in sealing performance. A surge flask in the system is formed into a loop together with the in-vitro stress culture device for the blood vessel through an input pipeline and an output pipeline; the input pipeline is provided with a constant flow pump and a flow sensor, and the output pipeline is provided with a pressure sensor; a gas regulating valve, the constant flow pump, the flow sensor and the pressure sensor are respectively connected with a PC (personal computer). The system and the culture method can be used for precisely controlling the pressure and flow in a culture process and improving the reliability of a culture result.

The invention discloses a method for establishing an intracranial vessel simulation three-dimensional stenosis model based on transfer learning. The method comprises the following steps: acquiring a bright blood image group and an enhanced black blood image group of an intracranial vessel; performing image registration by using a registration method based on mutual information and an image pyramidto obtain a registered bright blood image group; utilizing the registered bright blood image group to obtain an MIP image in each direction; obtaining a two-dimensional blood vessel segmentation image based on the MIP image as a target domain and a fundus blood vessel image; synthesizing the two-dimensional blood vessel segmentation images in the three directions by using a back projection methodto obtain first three-dimensional blood vessel body data; obtaining an intracranial blood vessel simulation three-dimensional model by utilizing the second three-dimensional blood vessel body data corresponding to the registered bright blood image group; and for each section of blood vessel in the model, obtaining a numerical value of a target parameter representing the stenosis degree of the section of blood vessel, and marking the intracranial blood vessel simulation three-dimensional model by utilizing the numerical value of the target parameter to obtain a simulated three-dimensional intracranial vessel stenosis analysis model.

The present disclosure relates to a device configured to move within a body cavity, such as the gastrointestinal tract, in particular, the small intestine, and methods of using the device. The presently disclosed device may be self-driving, and the articulation of a tip of the device may be controlled and fine tuned. The presently disclosed device may be used in a variety of body cavities such as a vascular body lumen, a digestive body lumen, a respiratory body lumen, or a urinary body lumen, for example, for endoscopic purposes, for delivering a substance into the body cavity, for removing a substance or tissue from the body cavity, for capturing an image of the body cavity, and/or for performing an operation of a tissue or organ using the device.

The invention belongs to the field of biomedical engineering, provides a blood vessel culture experiment cavity device capable of being repeatedly sterilized at high temperature, uses a blood vessel connecting tube with adjustable length and a convenient blood vessel mounting device, and provides an experiment cavity device capable of realizing blood vessel in-vitro simulation culture and being used for simulating blood flow stimulation on blood vessels. The blood vessel is assembled through an external fixing device, so that the blood vessel is convenient to assemble and easy to implement, and the pollution risk during operation is reduced; meanwhile, the blood vessel is placed into the blood vessel culture cavity in a pressing-in mode.

The invention discloses a quality testing method dynamic test phantom simulating cardiovascular motion for quality evaluation of CT imaging, and its control principle and quality testing method. The dynamic test phantom includes: a control system, an electric cylinder unit, a piston pump unit, a fluid circuit unit and a cardiovascular phantom; the control system includes a control box and a control PC, wherein the control box includes a PLC control system and an electrocardiogram generator, and the PLC control system is connected with the control PC and the electrocardiogram generator respectively; the electric cylinder unit includes an electric cylinder drive unit and an electric cylinder transmission unit, wherein the electric cylinder drive unit is connected with the PLC control system, and the electric cylinder transmission unit is connected with the electric cylinder drive unit; the piston pump unit is connected with the electric cylinder transmission unit; the fluid circuit unit includes a fluid confluence module and fluid pipelines, which are connected with the piston pump unit and the cardiovascular phantom respectively; and the cardiovascular phantom includes a ventricular phantom, coronary artery phantoms and a water tank. The dynamic test phantom according to the invention can simulate ventricular strokes and multiple motion phases, and has standard models of normal heart rate, arrhythmis, coronary artery stenosis, etc.

Many medical procedures involve the implantation of an element in a vascular body. Current imaging techniques allow the positioning of such expandable elements to be checked, before and after implantation, using contrast bursts into the blood from a pigtail catheter. When the implantation of the medical device needs to be performed quickly, the pigtail catheter is pulled back briskly. This process is prone to error, because at the point of implantation, a medical professional has many other factors to consider, as well as the withdrawal of the catheter. If an implantable device traps the pigtail catheter during or after expansion, undesirable results can occur, such as having to pull sharply on the catheter to remove it, and in the process, disrupting the newly implanted device. This application discusses a technique for automatically generating a region of implantation around a medical device prior to and during implantation. If a second medical device, such as a pigtail catheter, strays into the area, an alarm can be generated to warn a medical professional to withdraw the catheter, before deployment continues.

The invention discloses an experiment simulation device for cardiovascular diseases. The device comprises a combined box body, bases, a tray, a PC controller, a transparent cover cylinder, a cardiovascular phantom and a liquid storage box, the left base and the right base are installed at the bottom end of the interior of the combined box body, and fences are symmetrically arranged on the two sides of the top end of the tray; the PC controller and the transparent cover cylinder are arranged on the left side and the right side of the interior of the combined box body correspondingly, the cardiovascular phantom is arranged in the transparent cover cylinder, the liquid storage box is fixed to the center of the interior of the combined box body, and the output end of a water pump communicateswith a plurality of liquid supply pipes; and the bottom of the cardiovascular phantom is correspondingly communicated with a plurality of return pipes. An experiment simulation instrument is providedwith a packaging protection structure convenient to open and close, rotating adjustment and fixing are convenient, the display effect of the experiment simulation device is improved, the functions ofautomatic control and visual display are achieved, and therefore the cardiovascular disease experiment simulation effect is improved.

The invention discloses a cerebral angiography simulation training assembly, which comprises a simulation blood vessel body, a mounting flat plate and a blood vessel tortuosity position adjusting part, the simulation blood vessel body is cooperatively installed and fixed on the mounting flat plate, a plurality of screw mounting seats are uniformly distributed on the mounting flat plate, and the adjusting part comprises a plurality of screw bodies. The screw body is detachably and movably mounted on the screw mounting seat, and the screw body can adjust the position of the simulated blood vessel body and change the tortuosity of the simulated blood vessel body; and the liquid inlet end of the simulated blood vessel body is hermetically connected with an external water source for continuous perfusion, and the liquid outlet end of the simulated blood vessel body is connected with a liquid collecting device. The invention further discloses a using method of the simulation training assembly. The whole actual interventional surgery operation can be simulated, different blood vessel tortuosity can be adjusted according to training difficulty, a learner can adjust different training difficulty to carry out practical operation training, the learning effect is improved, the training cost is reduced, and finally the operation skill of the learner is improved.