15results about "Measurements using NMR spectroscopy" patented technology

A method for relaxation time determination includes delivering a series of radio frequency (RF) pulses in a sequence to a specimen having a magnetic resonance spin system. The pulses are separated by equal time intervals and the sequence has a duration comparable or greater than a spin-lattice relaxation time for the spin system. The method includes receiving a response after each RF pulse in the series. The response includes a free induction decay and spin echoes. The method includes generating a series of single point imaging (SPI) images from each response. Each SPI image of the series corresponds to an RF pulse in the series. The method includes converting SPI images to a spin-spin relaxation map and a spin-lattice relaxation map.

The application discloses a kind of nuclear magnetic resonance spectrum peak position detection method, device and readable medium, by obtaining two-dimensional spectrum based on spin echo phase change spectrum, SEcho-Net neural network is constructed and trained, SEcho-Net neural network includes coding layer and decoding layer, coding layer includes indirect dimension down-sampling module and direct dimension down-sampling module, indirect dimension down-sampling module is used to compress two-dimensional spectrum based on spin echo phase change spectrum, and first feature vector is obtained, first feature vector is input in direct dimension down-sampling module and extracts key information related to spectrum peak position, and obtains key feature, and decoding layer includes direct dimension up-sampling module and step-by-step dimension reduction module, direct dimension up-sampling module is used to recover spectrum information from key feature, and second feature vector is obtained, and second feature vector is input in step-by-step dimension reduction module and carries out feature extraction, and obtains spectrum peak pure chemical shift position information.The method has low experimental requirements, and can accurately locate spectrum peak position.

An NMR-DNP probe head (1) comprises a probe holder (2) for receiving a probe vessel (4) containing a probe substance surrounded by an RF coil (3), a temperature control device for temperature control of the probe substance, a microwave guide (5) for supplying microwave radiation into the probe volume, and an illumination device having a light guide (6) for photoinduced electron excitation of probe substance in the probe volume.The probe head is characterized in that the temperature control unit includes a temperature control channel (7) through which temperature control fluid can be supplied to the sample vessel for temperature control of the sample substance during NMR measurement operation, that the sample-side end of the optical fiber is arranged in the temperature control channel, and that a deflecting mirror (8) is arranged in the temperature control channel between the sample-side end of the optical fiber and the sample vessel, which directs light exiting the optical fiber onto the sample substance in the sample volume of the sample vessel. This allows for additional light excitation with an adjustable beam distance to illuminate the NMR sample within the probe head without negatively affecting the magnetic field or the RF. Furthermore, optical excitation in the UV range is also possible. The optical fibers are integrated into the probe head with an extremely small bending radius.

Described herein is a method for transferring a two-spin order of a molecule (e.g. parahydrogen) into a hyperpolarization of at least one heteronucleus, the method comprising the steps of: providing a molecule (e.g. parahydrogen pH2) comprising two protons and at least one heteronucleus (S3, S4), the protons having nuclear spins being coupled to a nuclear spin of the at least one heteronucleus; exposing the protons and the at least one heteronucleus to an e.g. homogeneous magnetic field (B0) in a z-direction, the z-direction forming a right-handed orthogonal coordinate system with an x- and a y-direction; and applying a sequence of radio frequency pulses to the protons and the at least one heteronucleus in order to transfer said two-spin order into the hyperpolarization of the at least one heteronucleus, wherein said sequence of radio frequency pulses comprises a first, a second, and a third group (NA, NB, NC) of 180° radio frequency pulses, wherein the first group (NA) of 180° radio frequency pulses is consecutively applied nA times during a first time interval (τA) and wherein the second group (NB) of 180° radio frequency pulses is consecutively applied nB times during a second time interval (τB) after the last first group, and wherein the third group (NC) of 180° radio frequency pulses is consecutively applied nC times during a third time interval (τC) after the last second group, wherein nA, nB, nC are integer numbers, respectively.

There is provided a solid-state nuclear magnetic resonance, NMR, probe (10). The probe (10) comprises: a cylindrical stator (103), the cylindrical stator (103) configured to receive a cylindrical sample rotor (107); a single gas input (111), configured to provide gas to the cylindrical stator (103); wherein the single gas input (111) is configured to be orientated to direct the gas along an inner surface of the cylindrical stator (103) thereby to cause a double rotation of the cylindrical sample rotor (107).

A method of determining a content of an element by mass of a selected substance. The method comprises preparing a reference density calibration data-group and applying the reference density calibration data-group for determining the content of the element by mass of the selected substance. The preparation of the reference density calibration data-group comprises providing a number of primary reference samples from one or more primary reference substance(s) determining an NMR intensity of at least one reference isotope for each of the primary reference samples, and generating the reference density calibration data-group. The determination of the content of the element by mass of the selected substance comprises determining an NMR intensity of at least one sample isotope of the sample and a density of the sample, and based on the determined NMR intensity and density of the sample, determining a second parameter representing the content of the element by mass of the selected substance.

The syntheses of a series of verdazyl mono- and biradicals, as well as verdazyl-nitroxide biradicals, are described for high-field dynamic nuclear polarization nuclear magnetic resonance (DNP NMR) spectroscopy. These radicals were examined in high-field DNP NMR experiments (600 MHz / 395 GHz), by measuring 1H signal enhancements directly and through 13C{1H} cross- polarization experiments. X-band EPR, 1H DNP field profiles, and experiments to determine the nuclear build-up times were performed for verdazyl-nitroxide biradicals VerTEMPol and VerTEKol. These hybrid biradicals provide enhancements of up to 100-fold increased signal intensities, representing >104-fold time savings, and approximately 4 times as high as that of the nitroxide biradical TEKPol, a commonly used polarizing agent in the field.

A compound having (A) 40-99.99 weight percent of at least one thermoplastic or thermoset polymer material selected as a halogenated or perhalogenated polymer; (B) 0.01-60 weight percent of at least one inorganic particulate diamagnetic or paramagnetic material; and (C) 0-39.99 weight percent of at least one additive different from (B). The compound is proposed as a construction material in the detection-relevant spatial area of a nuclear magnetic resonance device with a static magnetic field of at least 1 Tesla, and furthermore corresponding constructional elements, in particular sample holders, are proposed as well as method of manufacturing such constructional elements and uses of such constructional elements.

The invention pertains to a method for controlling an MRI-system (1), comprising the steps: - providing a TONE-pulse scheme comprising multiple ramped RF-pulses, - applying TONE-pulses (T) according to the TONE-pulse scheme in form of pulse-trains (P) with a binomial application-scheme to the MRI-system (1). Furthermore, the invention describes a device, a control device and a MRI-system.

The invention relates to improved formation protocols for NIB hard carbon anodes in superconcentrated ionic liquid electrolytes. In contrast to established methods for carbonate-based solvents, a high current density 2 C formation protocol resulted in the highest specific capacity during subsequent cycling at 1 / 2 C current density, along with the lowest EIS resistance, compared with 1 C and 1 / 10 C formation protocols. Variable cycling conditions (e.g., 1 / 5 C for long term cycling) were not influenced by the high C-rate treatment, demonstrating the necessity of applying high rate formation protocols for conditioning in these electrolytes. XPS and NMR analysis revealed a thinner SEI layer was formed after high C-rate formation, which can facilitate the Na+ charge transfer and diffusion across the electrolyte / electrode boundary.

An NMR-DNP probe head comprises a probe holder for receiving a sample vessel containing a sample substance surrounded by an RF coil, a temperature control device for maintaining the temperature of the sample substance, a microwave guide for supplying microwave radiation into the sample volume, and an illumination device comprising an optical fiber for photoinduced electron excitation of the sample substance in the sample volume. The temperature control device comprises a VT channel through which temperature control fluid can be supplied to the sample vessel during NMR measurement to maintain the temperature of the sample substance, the sample-side end of the optical fiber is arranged in the VT channel, and a deflecting mirror is arranged in the VT channel between the sample-side end of the optical fiber and the sample vessel that directs light exiting the optical fiber onto the sample substance in the sample volume of the sample vessel.

Embodiments include a system for material detection and identification. The system may include an RF transmit device configured to transmit into an environment an RF signal at a resonance frequency. The system may also include an RF receiver device configured to receive a response signal from the environment. The system may further include a communication device connecting the RF transmit device and the RF receiver device. The communication device may include a control module. The system may include a geolocation device. The control module may be configured to receive geolocation data from the geolocation device, analyze the response signal for resonance characteristics that indicate a presence of a material, and identify the material to a user when the presence of the material is indicated by the resonance characteristics. Methods for material detection and identification are also described. Methods may involve obtaining geolocation data.

In some aspects, a resonator device includes a dielectric substrate, a ground plane on a first side of the substrate, and conductors on a second, opposite side of the substrate. The conductors include first and second resonators and two baluns. Each balun includes a feed, a first branch and a second branch. The feed is connected to the first and second branches, and the first and second branches are capacitively coupled to the respective first and second resonators. The first branch includes a delay line configured to produce a phase shift relative to the second branch. The resonator device includes a sample region configured to support a magnetic resonance sample between the first and second resonators.

A system and method include an analysis control unit configured to receive nuclear magnetic resonance (NMR) data of a sample. A reference database is in communication with the analysis control unit. The reference database stores standard data including information regarding a plurality of standards for chemical compounds, and may also store information regarding quantum mechanical spectral analysis (QMSA) model data and test method data. The analysis control unit is further configured to compare the NMR data with the standard data to determine if the NMR data is associated with one of the plurality of standards, and identify one or more differences between the NMR data and the one of the plurality of standards.

Systems and methods are described for investigating brain-wide CSF flow dynamics and understanding the role of neural activity, including an Echo-Planar Time-resolved Imaging (EPT)I CSF flowmetry technique that can simultaneously acquire i) phase-contrast 4D CSF flow, ii) T2*-BOLD fMRI, and iii) T2- and S0-contrast changes. EPTI eliminates the distortion and blurring artifacts in Echo-Planar Imaging (EPI), as well as resolving multi-echo images within the readout, allowing for the separation of various contrasts including T2*, T2, and flow-encoded S0. This separation is particularly useful for obtaining clean BOLD-fMRI signals.