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31 results about "Mri techniques" patented technology

Magnetic resonance imaging (MRI) is an imaging technique used primarily in medical settings to produce high quality images of the inside of the human body. MRI is based on the principles of nuclear magnetic resonance (NMR), a spectroscopic technique used by scientists to obtain microscopic chemical and physical information about molecules.

Selective sampling for assessing structural spatial frequencies with specific contrast mechanisms

The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and / or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of signal at selected values in k-space, with multiple successive acquisitions at individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only signal values at select places in k-space, along selected directions, enables much higher in vivo resolution than is obtainable with current MRI techniques.
Owner:BIOPROTONICS

Controlling telemetry during magnetic resonance imaging

The invention is directed techniques for coordinating telemetry of medical devices with magnetic resonance imaging (MRI) techniques. By coordinating telemetry of a medical device with the performance of MRI techniques with, the use of telemetry during MRI may be facilitated. In one example, information indicative of electromagnetic radiation bursts in MRI techniques can be communicated to the medical device prior to execution. In another example, the medical device may identify the electromagnetic radiation bursts, e.g., by measuring for the presence of such bursts. In either case, the medical device can adjust its telemetry to improve communication during MRI.
Owner:MEDTRONIC INC

Controlling telemetry during magnetic resonance imaging

The invention is directed techniques for coordinating telemetry of medical devices with magnetic resonance imaging (MRI) techniques. By coordinating telemetry of a medical device with the performance of MRI techniques with, the use of telemetry during MRI may be facilitated. In one example, information indicative of electromagnetic radiation bursts in MRI techniques can be communicated to the medical device prior to execution. In another example, the medical device may identify the electromagnetic radiation bursts, e.g., by measuring for the presence of such bursts. In either case, the medical device can adjust its telemetry to improve communication during MRI.
Owner:MEDTRONIC INC

Methods and apparatus for measuring capillary pressure in a sample

A method and apparatus are provided for measuring a parameter such as capillary pressure in porous media such as rock samples. The method comprises mounting a sample in a centrifuge such that different portions of the sample are spaced at different distances from the centrifuge axis, rotating the sample about the axis, measuring a first parameter in the different portions of the sample, and determining the value of a second parameter related to the force to which each portion is subjected due to rotation of the sample. In one embodiment, the first parameter is relative saturation of the sample as measured by MRI techniques, and the second parameter is capillary pressure.
Owner:GREEN IMAGING TECH

Structure assessment using spatial-frequency analysis

The disclosed innovation is a method for acquiring spatial frequency spectra from specific locations in a 3D sample using modifications of the current MRI techniques for localized NMR spectroscopy. The innovation in its simplest abstraction is to add the use of a read out gradient to the current NMR spectroscopy pulse sequences and record the resultant echo. These techniques generate spectra from a selected region or generate an image of the results over a region of the sample. These methods can be applied to analyzing the structure of trabecular bone as well as for analyzing or diagnosing disease in cases where there is a difference in the spatial frequency power spectrum due to physiologic or disease processes. Various embodiments are disclosed.
Owner:OSTEOTRONIX MEDICAL PTE LTD

Magnetic field gradient structure characteristic assessment using one dimensional (1D) spatial-frequency distribution analysis

The disclosed innovation is a method for acquiring spatial frequency spectra from specific locations in a 3D sample using modifications of the current MRI techniques for localized NMR spectroscopy. The innovation in its simplest abstraction is to add the use of a read out gradient to the current NMR spectroscopy pulse sequences and record the resultant echo. These techniques generate spectra from a selected region or generate an image of the results over a region of the sample. These methods can be applied to analyzing the structure of trabecular bone as well as for analyzing or diagnosing disease in cases where there is a difference in the spatial frequency power spectrum due to physiologic or disease processes. Various embodiments are disclosed.
Owner:OSTEOTRONIX MEDICAL PTE LTD

Selective sampling for assessing structural spatial frequencies with specific contrast mechanisms

The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in-vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and / or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of selected values in k-space, with multiple successive acquisitions of individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only select values in k-space along selected directions, enables much higher in-vivo resolution than is obtainable with current MRI techniques.
Owner:BIOPROTONICS

Magnetic resonance imaging using hyperpolarization of liquids or solids by light with orbital angular momentum

In magnetic resonance imaging (MRI), selected magnetic dipoles in a subject are aligned with a main magnetic field for later manipulation, and signals received after such manipulations are used to create image representations of the subject. One drawback is that even powerful magnetic fields can only align a very small percentage of dipoles in the region of the field. Electromagnetic radiation endowed with orbital angular momentum (OAM) aligns dipoles along the direction of travel of the radiation, but at a much higher percentage; as high as 100% of the dipoles in the region can be aligned. Resultantly, resonance signals emanating from the region are several orders of magnitude stronger than signals emanated using traditional MRI techniques. All electromagnetic radiation, including visible light can be endowed with OAM and used to hyperpolarize a region of interest.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV

Selective sampling magnetic resonance-based method for assessing structural spatial frequencies

The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in-vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and / or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of selected values in k-space, with multiple successive acquisitions of individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only select values in k-space along selected directions, enables much higher in-vivo resolution than is obtainable with current MRI techniques.
Owner:BIOPROTONICS

Selective sampling magnetic resonance-based method for assessing structural spatial frequencies

The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in-vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and / or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of selected values in k-space, with multiple successive acquisitions of individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only select values in k-space along selected directions, enables much higher in-vivo resolution than is obtainable with current MRI techniques.
Owner:BIOPROTONICS

Color mapped magnetic resonance imaging

A method and system estimate the risk of malignancy of a given region of interest using noninvasive MRI techniques. The determination of risk is based on the morphology and kinetic enhancement of a region of interest. In addition, the method and system use the type of the enhancement curve to determine the level of risk associated with a given region of interest. The region of interest can be a lesion, tumor, or other unknown. The imaging can be done with the aid of a contrast agent. Regions meeting component concentration criteria, time-change dynamic criteria and the like are distinctly colored and displayed on a single image. Different colors can be shown locally to identify predetermined levels of risk, and / or associated with predetermined compositions such as contrast agents, or to show the presence of silicone.
Owner:AURORA IMAGING TECH

Signal inhomogeneity correction and performance evaluation apparatus

Methods for correcting inhomogeneities of magnetic resonance (MR) images and for evaluating the performance of the inhomogeneity correction. The contribution of both transmit field and receiver sensitivity to signal inhomogeneity have been separately considered and quantified. As a result, their negative contributions can be fully corrected. The correction method can greatly enhance the accuracy and precision of MRI techniques and improve the detection sensitivity of pathophysiological changes. The performance of signal inhomogeneity correction methods has been evaluated and confirmed using phantom and in vivo human brain experiments. The present methodologies are readily applicable to correct signal intensity inhomogeneity artifacts produced in different imaging modalities, such as computer tomography, X-ray, ultrasound, and transmission electron microscopy.
Owner:YALE UNIV +1

Selective sampling for assessing structural spatial frequencies with specific contrast mechanisms

The disclosed embodiments provide a method for acquiring MR data at resolutions down to tens of microns for application in in vivo diagnosis and monitoring of pathology for which changes in fine tissue textures can be used as markers of disease onset and progression. Bone diseases, tumors, neurologic diseases, and diseases involving fibrotic growth and / or destruction are all target pathologies. Further the technique can be used in any biologic or physical system for which very high-resolution characterization of fine scale morphology is needed. The method provides rapid acquisition of signal at selected values in k-space, with multiple successive acquisitions at individual k-values taken on a time scale on the order of microseconds, within a defined tissue volume, and subsequent combination of the multiple measurements in such a way as to maximize SNR. The reduced acquisition volume, and acquisition of only signal values at select places in k-space, along selected directions, enables much higher in vivo resolution than is obtainable with current MRI techniques.
Owner:BIOPROTONICS

Brush-arm star polymer imaging agents and uses thereof

Disclosed are methods, compositions, reagents, systems, and kits to prepare nitroxide-functionalized brush-arm star polymer organic radical contrast agent (BASP-ORCA) as well as compositions and uses thereof. Various embodiments show that BASP-ORCA display unprecedented per-nitroxide and per-molecule transverse relaxivities for organic radical contrast agents, exceptional stability, high water solubility, low in vitro and in vivo toxicity, and long blood compartment half-life. These materials have the potential to be adopted for tumor imaging using clinical high-field 1H MRI techniques.
Owner:MASSACHUSETTS INST OF TECH +1

Method and system for performing upright magnetic resonance imaging of various anatomical and physiological conditions

Vasculature or parenchyma is imaged using upright MRI techniques, on patients who may have conditions such as congestive heart failure, or otherwise be healthy. When an individual is horizontal, venous drainage is minimized, causing the vessels to remain engorged, also referred to herein as vascular congestion. Vascular congestion results in an enlarging of the vessels and surrounding tissue causing the vessels to be more visible on MRIs. The decrease in vascular visibility in upright subjects is in part, due to an increase in venous drainage. Patients suffering from coronary and / or pulmonary deficiencies (e.g. CHF) experience decreased rates and degrees of venous drainage. In one embodiment, the present invention uses upright imaging to visualize these enlarged vessels.
Owner:FONAR

Magnetic resonance imaging using hyperpolarization of liquids or solids by light with orbital angular momentum

In magnetic resonance imaging (MRI), selected magnetic dipoles in a subject are aligned with a main magnetic field for later manipulation, and signals received after such manipulations are used to create image representations of the subject. One drawback is that even powerful magnetic fields can only align a very small percentage of dipoles in the region of the field. Electromagnetic radiation endowed with orbital angular momentum (OAM) aligns dipoles along the direction of travel of the radiation, but at a much higher percentage; as high as 100% of the dipoles in the region can be aligned. Resultantly, resonance signals emanating from the region are several orders of magnitude stronger than signals emanated using traditional MRI techniques. All electromagnetic radiation, including visible light can be endowed with OAM and used to hyperpolarize a region of interest.
Owner:KONINKLIJKE PHILIPS ELECTRONICS NV

System And Method For Continuous Wave Constant Amplitude On-Resonance And Off-Resonance Spin-Lock For Magnetic Resonance Imaging

MRI techniques provide robust imaging in the presence of inhomogeneity in the B1 (RF) and / or B0 magnetic fields. The techniques include using a magnetization prep sequence that includes an adiabatic half passage (AHP) followed by a spin-lock pulse, followed by a reverse AHP, after which a data acquisition sequence can be applied. The AHP and reverse AHP can have amplitude and frequency modulated to sweep through a region of frequency space. The RF amplitude of the AHP and reverse AHP can be designed to be equal to the spin-lock amplitude. Quantification of a magnetization relaxation parameter(e.g., T1rho) can use a modified relaxation model that accounts for relaxation effects during the reverse AHP. A dual-acquisition technique in which the reverse AHP of the second magnetization prep sequence has opposite frequency modulation to the reverse AHP of the first magnetization prep sequence can also be used.
Owner:THE CHINESE UNIVERSITY OF HONG KONG

Method and system capable of accurately positioning and accurately reckoning encephalic region

The invention discloses an encephalic region accurate positioning and calculating method and a system based on nuclear magnetic resonance imaging (MRI). The method and the system are invented on the basis of MRI techniques; electrodes and / or imaging fluid markers are adopted to obtain an electrode imaging and / or encephalic region coordinate system. According to the method, accurate positioning canbe achieved, and accurate calculation can be conducted on encephalic region within a certain range. The establishment of the method can solve the problems of accurate positioning and calculation of encephalic region in animal experiments; under the condition that the positioning accuracy is guaranteed, the number of encephalic region positioning times can be reduced, and damage to animals and MRIscanning cost are reduced.
Owner:SHENZHEN INST OF ADVANCED TECH

Intravoxel incoherent motion MRI 3-dimensional quantitative detection of tissue abnormality with improved data processing

PendingCN110785123AImage enhancementMedical imagingIntravoxel incoherent motionThree-dimensional space
Liver fibrosis can be detected using intravoxel incoherent motion (IVIM) MRI techniques. For example, using a diffusion weighted MRI imaging sequence, scans of a patient's liver can be made. Signal intensity data acquired in MRI scans can be fitted to a bi-exponential model of signal attenuation representing a combination of a fast component associated with perfusion and a slow component associated with diffusion in the tissue. This allows the extraction of parameters representing the slow and fast diffusion rates, as well as the fractional contributions of the fast and slow components. Analysis of a combination of these parameters in a multi-dimensional space (e.g., in a three-dimensional space) yields a metric that can distinguish healthy liver from fibrotic liver.
Owner:THE CHINESE UNIVERSITY OF HONG KONG
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