Method and system capable of accurately positioning and accurately reckoning encephalic region

Abstract

The invention discloses an encephalic region accurate positioning and calculating method and a system based on nuclear magnetic resonance imaging (MRI). The method and the system are invented on the basis of MRI techniques; electrodes and / or imaging fluid markers are adopted to obtain an electrode imaging and / or encephalic region coordinate system. According to the method, accurate positioning canbe achieved, and accurate calculation can be conducted on encephalic region within a certain range. The establishment of the method can solve the problems of accurate positioning and calculation of encephalic region in animal experiments; under the condition that the positioning accuracy is guaranteed, the number of encephalic region positioning times can be reduced, and damage to animals and MRIscanning cost are reduced.

Description

technical field [0001] The invention relates to a method and system capable of accurately locating and estimating brain regions, which is not only suitable for vertical recording, but also for oblique and angled experimental recording. Background technique [0002] In the prior art, in the field of neuroscience, in order to understand the neural mechanism of the brain, the relationship between neural networks in the brain and brain regions, and understand the pathogenesis of brain diseases, it is necessary to record the neural activity of the target brain area, and then The recorded neural activity is analyzed with respect to macroscopic behavior or disease. Therefore, precise positioning of the brain region is very important. Only accurate positioning can ensure the accuracy of the recorded data, thereby ensuring a correct understanding of the function of the brain region. [0003] The terms involved in the present invention are explained as follows: [0004] Magnetic res...

AI Technical Summary

Problems solved by technology

[0021] In the first two methods mentioned above, the markers are placed horizontally, so they have a common disadvantage, that is, they are only suitable for recordings with vertical directions, and are not suitable for records with oblique angles.

If the angle is tilted, the positioning will not be accurate

In addition, the first method has disadvantages: the target brain area has no reference mark in the direction of the ML axis. The second method also has the following disadvantages: (1) The imaging fluid capsule is large in size and cannot accurately locate smaller brain regions; (2) ) The skin itself will move and shrink to a certain extent, which will cause inaccurate positioning

[0023] To sum up, the current method can locate brain regions to a certain extent, but cannot accurately locate brain regions with oblique angle records; position) cannot be accurately estimated

[0024] Therefore, in order to solve the problems in the current method, that is, the inability to complete the recording that requires an inclination angle, the problem that the brain area of ​​the experimental target cannot be accurately located or estimated, the present invention provides a method and system that can accurately locate and estimate the brain area

Images