64 results about "Superparamagnetism" patented technology

The invention relates to the technical field of oil gas well tracing monitoring, in particular to a preparation method and application of an oil gas well tracing monitoring magnetic nano tracer agent. Comprising the following steps: dissolving FeCl3, FeSO4. 7H2O and doped metal salt in water, and introducing N2 to remove oxygen; the initial reaction temperature is 85 DEG C, rapidly adding ammonia water, reacting to generate Fe3O4 nanoparticles, doping elements, reducing the temperature to 60 DEG C, and firstly adding sodium citrate for primary carboxyl modification; adding a mixed solution of oleic acid and PEG twice; the pH value of the reaction system is controlled to be 9.5-10.5 in the whole process. The method has the beneficial effects that the doping amount is remarkably increased, the doping amount of doped elements is multiple times of that in the prior art, and the detection sensitivity is remarkably improved; in addition, oleic acid / PEG composite modification is adopted instead of single citric acid modification, so that the tracer is kept stably dispersed in high-salinity formation water; the superparamagnetism facilitates magnetic separation and recovery, and is suitable for harsh formation conditions.

The invention relates to a method for preparing superfine magnetic iron oxide nanoparticles by using liquid nitrogen as a reaction medium, which comprises the following steps: S1, dropping a mixed aqueous solution containing Fe < 3 + > and Fe < 2 + > as a precursor solution and ammonia water into the liquid nitrogen at the same time; s2, stirring while adding ammonia water, and when the mixed solution becomes black, adding oleic acid for particle coating to obtain nanoparticles; and S3, sequentially washing the nano-particles with deionized water and acetone, collecting, filling liquid nitrogen into the obtained nano-particles, and freeze-drying to obtain the superfine magnetic iron oxide nano-particles. The method is easy to operate, the agglomeration phenomenon is effectively prevented under the low-temperature condition of liquid nitrogen, and the prepared nanoparticles have better dispersity and magnetism; due to the use of liquid nitrogen in the reaction process and a subsequent freeze-drying method, the formation of superfine nano-particle powder with uniform size is effectively realized, and the obtained nano-particles have superparamagnetism; the method is environment-friendly and low in cost.

An object of the present application is to provide a magnetic particle including a secondary particle in which a plurality of primary particles are aggregated, each primary particle having a particle diameter deemed to exhibit superparamagnetism, and the secondary particle exhibiting a larger particle diameter. [Solution] This object is achieved by magnetic particles including secondary particles in which a plurality of primary particles are aggregated, in which the secondary particles have an average particle diameter of 500 nm or more and 5000 nm or less, and in which the plurality of primary particles have an average particle diameter of 2 nm or more and 20 nm or less.

The invention provides a magnetic nano material for enriching benzimidazole compounds and application of the magnetic nano material. The magnetic nano enrichment material comprises a core body, wherein the core body is composed of superparamagnetic ferroferric oxide; the shell covers at least part of the surface of the core body, and the shell is made of a covalent organic framework material formed by a repeating unit as shown in a formula I in the specification. The enrichment material has a porous and ordered crystal structure and a high specific surface area, and shows excellent adsorption performance, including high adsorption capacity, rapid adsorption kinetics, good selectivity and reusability. Therefore, the benzimidazole compound in a complex sample can be efficiently enriched and purified, and an effective means is provided for trace detection of the compound residues in a food matrix.

The present application relates to a kind of high-throughput staphylococcus aureus enterotoxin microfluidic chip detection method and application based on chain quantity amplification enhanced fluorescence.The microfluidic chip is provided with fluorescence sensor, and the fluorescence sensor includes identification probe and signal probe;The identification probe is composed of magnetic nanoparticle, nucleic acid aptamer H1 of target to be measured and target aptamer complementary chain H2, and the signal probe is composed of nanomaterial with signal amplification function and three oligonucleotides H3, H4, H5.The present application combines MNPs-ssDNA-AuNPs sandwich structure system and microfluidic chip, realizes detection signal amplification using the excellent superparamagnetic property of MNPs and the high loading capacity of AuNPs, constructs high-throughput, high-sensitivity fluorescence sensing technology for SEA, SEB and SEC1 detection, simplifies experimental process, and builds the rapid, efficient detection platform of multiple pollutants in food.

The invention discloses an acanthosphere-shaped multi-interface type metal oxide magnetic particle and a preparation method and application thereof.The magnetic particle comprises a core composed of magnetic nanoparticles and a shell layer composed of titanium oxide nanosheet spines arranged in a radial mode, and the magnetic particle has superparamagnetism, high specific surface area and rich active sites; and a large number of trap spaces matched with the exosome scale range, so that the method can be used for efficiently enriching and separating the exosome from the biological fluid. Meanwhile, the magnetic core has an out-phase junction composed of amorphous phase titanium oxide and anatase phase titanium oxide, a heterojunction interface composed of titanium oxide and the magnetic core and an ordered spine microstructure, the synergistic effect of the multi-interface effect and the point effect is fully exerted under laser irradiation, the excellent ultraviolet absorption capacity and electron-hole separation efficiency are shown, and the magnetic core has the good application prospect. The method is used for laser desorption ionization mass spectrometry, efficient in-situ pyrolysis of the exosome is achieved, desorption and ionization of metabolite in a lysis solution are promoted, and a high-resolution mass spectrum of the metabolite of the exosome is obtained.

[Problem] To provide a superparamagnetic tunnel junction element and a computing system using same, the tunnel junction element having excellent operation stability (robustness) against an external magnetic field and being suitable for the computing system based on probabilistic computing. [Solution] This superparamagnetic tunnel junction element 10 comprises a first ferromagnetic layer group 14 including a ferromagnetic material, a second ferromagnetic layer group 12 including a ferromagnetic material, and a barrier layer 13 disposed between the first ferromagnetic layer group 14 and the second ferromagnetic layer group 12, wherein: the first ferromagnetic layer group 14 includes a 1-1st ferromagnetic layer 14A_1, a 1-2nd ferromagnetic layer 14A_2, and a first non-magnetic bonding layer 14B_1; the 1-1st ferromagnetic layer 14A_1 is composed of a ferromagnetic material, and the magnetization direction thereof varies with a first time constant; the first time constant is one second or shorter; and the first non-magnetic bonding layer 14B_1 contains at least one among Ru, Ir, Rh, Cr, and Cu.

Disclosed herein are methods and kits for purifying therapeutic-grade plasmid DNA using magnetic particles. In particular, the technology of the present disclosure relates to methods and kits for purifying therapeutic-grade plasmid DNA at a high degree of purity using magnetic particles with a siliceous oxide surface layer and a superparamagnetic core.

To provide: a fine particle which has superparamagnetism and which does not deteriorate when brought into contact with water; and a production method thereof.SOLUTION: A fine particle (1) according to the present invention includes γ-Fe2O3(5) contained in a matrix phase (3) containing SiO2. In the fine particle, an atom ratio (Si / Fe) between a silicon atom derived from SiO2 and an iron atom derived from γ-Fe2O3 is preferably 0.050 to 0.500, a coercive force is preferably 480A / m or less, and a saturation magnetization is preferably 40A m2 / kg or more.SELECTED DRAWING: Figure 1

The invention relates to a preparation and application method of a controllable microbial carrier, and belongs to the field of perishable organic solid waste biological treatment. The preparation method comprises the following steps: (1) modifying ferroferric oxide with oleic acid; and (2) synthesizing porous magnetic microspheres on the surface of oleic acid modified ferroferric oxide by a suspension polymerization method, namely the controllable microbial carrier. The obtained carrier has the advantages of porosity, superparamagnetism, large surface roughness, large particle size and the like, functional microbial flora can be effectively enriched and fixed, and the bioconversion efficiency of organic solid waste is greatly improved. The carrier can be regulated, controlled and recycled through an exogenous magnetic field, and meanwhile, a solid substrate and functional microorganisms in an organic solid waste aerobic or anaerobic biological treatment system can be effectively separated.

The present invention provides an EMI shielding device including a flame retarding, thermal interface material composite with a through plane thermal conductivity of no less than 30 W / mK and a dielectric withstanding voltage of no less than 1 kV / mm, where the composite includes at least one dielectric layer of self-aligned, carbon-based materials associated with superparamagnetic particles and at least one layer of fillers including a blend of dielectric heat transfer materials with a thermal or UV curable polymer or phase change polymer. The anisotropic heat transfer carbon-based materials associated with superparamagnetic materials are aligned under a low magnetic field strength of less than 1 Tesla to an orientation that results in a high thermal conductivity direction which can conduct the maximum heat from the adjacent device of the present composite. The present invention also provides a method for preparing the composite.

The application provides a superparamagnetic conductive fluid material, a preparation method thereof and a magnetically connected laminated photovoltaic module; the preparation method comprises the following steps: a) dissolving FeCl2*4H2O and FeCl3*6H2O in water, then adding an NH3*H2O aqueous solution to carry out a coprecipitation reaction, separating and cleaning a solid product to obtain a Fe3O4 magnetic fluid; b) mixing the Fe3O4 magnetic fluid obtained in the step a) with a nano-silver conductive adhesive and a diluent, and carrying out ultrasonic dispersion to obtain the superparamagnetic conductive fluid material. Compared with the prior art, the application first synthesizes a superparamagnetic conductive fluid material, then coats the superparamagnetic conductive fluid material on a battery sheet overlapping connection setting area in a coating mode, the superparamagnetic conductive fluid material is rapidly magnetized under the action of a magnetic field, and loses magnetism rapidly after the external magnetic field disappears; when a single battery sheet has a defect, the damaged battery sheet can be easily disassembled and replaced, so that the waste of the battery sheet is reduced; meanwhile, the superparamagnetic conductive fluid material can also be used for the recycling and disassembly of the module after retirement.

The present invention relates to an apparatus for softening a crystalline lens nucleus (100) in a cataract phacoemulsification treatment comprising an electric current pulse generator (11) to supply a pulse current to a handpiece (12), wherein the pulse current generates a pulsatile magnetic field, and to hydrodissect the lens nucleus with iron oxide nanoparticle solution to loosen the lens nucleus as well as to infiltrate the lens nucleus (14) with the iron oxide nanoparticles (13), characterised in that the needle tip (24) of the handpiece (12) conducts the generated pulsatile magnetic field to the lens nucleus which causes vibration of iron oxide nanoparticles which emanates a mechanical force to break interdigitating bonds between lens fibers, leading to a controlled softening and fragmenting of the lens nucleus, wherein the electric current pulse generator (11) is configured to produce pulse currents with adjustable voltage and frequency parameters, and the iron oxide nanoparticle solution (13) further comprises a superparamagnetic property functionalised with a biocompatible coating.

The invention relates to the technical field of semiconductor photocatalytic materials, in particular to a preparation method of a spherical Fe3O4 (at) ZnO nanosheet photocatalyst. According to the method, in an ethylene glycol solvent, Fe < 3 + > is used as an iron source, sodium acetate is used as a precipitator, PEG-1000 is used as a morphology guiding agent, and monodisperse spherical Fe3O4 is prepared through a hydrothermal method; then dispersing the spherical Fe3O4 into an aqueous solution containing PEG-20000 and PVP (Polyvinyl Pyrrolidone), and growing a ZnO nanosheet precursor on the surface of the spherical Fe3O4 through hydrothermal reaction again by taking zinc acetate as a zinc source and urea as a homogeneous precipitator; and finally performing high-temperature calcination to obtain a final product. Through the synergistic effect of the two-step hydrothermal method and the surfactant, tight heterojunction compounding of Fe3O4 and ZnO is realized, and the prepared catalyst has high specific surface area, rich active sites and superparamagnetism. The catalyst disclosed by the invention shows excellent photocatalytic degradation activity and cycling stability to organic pollutants under visible light, can be quickly separated and recycled by utilizing an external magnetic field, and has a wide application prospect in the field of wastewater treatment.

The invention discloses boron-rich magnetic nanoparticles and a preparation method and application thereof.The boron element content of the boron-rich magnetic nanoparticles is as high as 9-15 wt%, the boron-rich magnetic nanoparticles are prepared through a one-step solvothermal method, an iron oleate precursor, boric acid, phenyl ether and polyethylene glycol dicarboxylic acid are mixed, and then the mixture is subjected to a three-stage temperature programming reaction at the temperature of 90-120 DEG C, 180-220 DEG C and 250-270 DEG C to obtain the boron-rich magnetic nanoparticles; the prepared boron-rich nanoparticles are uniform in particle size and good in dispersity, have both high boron loading and superparamagnetism, and can significantly improve the tumor killing efficiency of BNCT and reduce the drug toxicity; the superparamagnetism can realize active targeting delivery guided by an external magnetic field, and the magnetic resonance imaging contrast agent can be used for avoiding the risk of magnetic agglomeration at the same time; fluorescence labeling and cell membrane or specific cell membrane protein modification are easily performed on the surfaces of the particles, so that the treatment effect is enhanced, and diagnosis and treatment integration guided by multi-modal imaging is realized; the boron-rich nanoparticles are simple and convenient in preparation process and easily available in raw materials, and have wide application prospects in tumor boron neutron capture therapy drugs.

The invention relates to Calpeptin magnetic nano drug-loaded particles of a targeted enrichment membrane layer and application, and belongs to the technical field of biological medicines. The invention designs a Calpeptin magnetic nano drug-loaded particle for targeting a middle membrane layer, the Calpeptin magnetic nano drug-loaded particle adopts a core-shell structure, a magnetic core is composed of superparamagnetic ferroferric oxide nano particles, and the core endows the material with response ability to an external magnetic field, so that the material can be used for preparing the drug-loaded particle. The polymer shell layer is formed by wrapping the surface of the magnetic core with polydopamine (PDA), and Calpeptin is covalently connected to a polydopamine shell. The Calpeptin magnetic nano drug-loaded particle disclosed by the invention solves the technical problem that a composite material cannot efficiently penetrate through an aorta wall and is specifically enriched in a middle membrane layer, so that a reliable directional intervention scheme with in-vivo experimental evidence support is provided for accurate treatment of TAAD.

The present application relates to the technical field of targeting carrier, in particular to a kind of magnetic nanoparticle targeting carrier for liver cancer and its use method, comprising: the superparamagnetic magnetite magnetic inner core with, the inner core is surface modified, and modification group is carboxyl;Platelet membrane layer that is tightly wrapped the inner core, and the platelet membrane layer is derived from the platelet of healthy individual;Gal and anti-PD-L1 antibody modified on the surface of the platelet membrane layer;Chemotherapeutic drug is loaded in the inner core, and the platelet membrane layer is combined with inner core by ultrasound fusion;The magnetic nanoparticle targeting carrier of the present application has significant therapeutic effect in the treatment of liver cancer, and the superparamagnetic magnetite magnetic inner core in the technical scheme of the present application not only provides magnetism for carrier, so that it can be guided to move directionally under external magnetic field, and accurately gather in tumor site, improve the concentration of drug in tumor tissue.

The invention relates to the technical field of optical materials, in particular to magnetic photonic crystal pigment powder as well as a preparation method and application thereof. The magnetic photonic crystal pigment powder is prepared from the following raw materials in parts by weight: 1 to 15 parts of superparamagnetic ferroferric oxide, 50 to 70 parts of nano microspheres, 15 to 50 parts of acrylate reactants, 0.1 to 3 parts of a photoinitiator and 50 to 120 parts of a solvent, the superparamagnetic ferroferric oxide is magnetic ferroferric oxide of which the surface is modified by a nonionic surfactant. The preparation method comprises the following steps: synthesizing non-ionic surfactant modified ferroferric oxide nanoparticles by a coprecipitation method, dispersing the non-ionic surfactant modified ferroferric oxide nanoparticles in a photonic crystal coating liquid, and carrying out coating, normalizing, photocuring and crushing processes to prepare the colorful magnetic photonic crystal pigment powder, the preparation method of the pigment powder is simple, convenient, low in cost, green and environment-friendly, and the preparation method is suitable for industrial production. The anti-counterfeit label is expected to be widely applied to various application scenes such as decoration and anti-counterfeit labels.

The invention relates to a magnetic visible light driven photocatalyst composite particle as well as preparation and application thereof. The photocatalyst composite particles are of a core-shell structure, each photocatalyst composite particle comprises a superparamagnetic material nano-particle serving as a core, a non-magnetic middle protective layer wrapping the core and a shell layer loaded on the middle protective layer, the shell layer comprises a visible light driven photocatalyst material BiOBrxI1-x, and the visible light driven photocatalyst material BiOBrxI1-x is a visible light driven photocatalyst material BiOBrxI1-x. Wherein x is the weight ratio of bromine to the total amount of halogen bromine and iodine, and x ranges from 0 to 1. The photocatalyst composite particle can be used for treating water containing pollutants such as drugs and / or personal care products, and can be used for quickly and efficiently carrying out photocatalytic degradation on the pollutants under the driving of visible light; and moreover, the photocatalyst composite particles can be quickly and conveniently recycled from a water-containing medium through a magnetic separation technology so as to be recycled.

The invention discloses a fluorescent functionalized bionic magnetic bead and a preparation method thereof. The magnetic bead preparation method comprises the following steps: 1) dissolving a hydrophobic monomer, a hydrophobic polymer, an initiator and fluorescent dye molecules in an organic solvent to obtain a solution A; dispersing magnetic nanoparticles in an organic solvent to obtain dispersion liquid B; 2) uniformly mixing the solution A and the dispersion solution B, adding a surfactant aqueous solution, and emulsifying to obtain an oil-in-water emulsion C; 3) dissolving a hydrophilic monomer in the surfactant aqueous solution to obtain a solution D; and mixing the oil-in-water emulsion C with the solution D, introducing nitrogen, heating, carrying out polymerization reaction, washing the product, and carrying out freeze drying to obtain the product. The magnetic beads show superparamagnetism and luminescence, and are uniform in particle size.

The invention discloses a nucleic acid aptamer composite material for enriching aflatoxin in food as well as a preparation method and application of the nucleic acid aptamer composite material. According to the composite material, a two-dimensional graphene oxide nanosheet modified by ferroferric oxide nanoparticles is used as a magnetic substrate, and the surface of the magnetic substrate is connected with a nucleic acid aptamer capable of specifically recognizing and combining aflatoxin through a covalent bond. By combining the high specific surface area and superparamagnetism of the magnetic substrate with the high specific affinity of the nucleic acid aptamer to aflatoxin, the technical problem of poor selectivity of a traditional adsorption material is solved. The composite material has high adsorption capacity and excellent selectivity on aflatoxin, and can be used for rapidly and efficiently enriching and purifying trace aflatoxin in complex matrix (such as milk, astragalus membranaceus and angelica sinensis) samples, so that the sensitivity and accuracy of subsequent instrument analysis are remarkably improved.

An electromagnetic material for an inductance for operation at cryogenic temperatures including, in an electrically insulating matrix, metal nanoparticles with superparamagnetic behavior of size less than or equal to 30 nm and having a magnetic permeability greater than or equal to 1.5 for a frequency between 5 GHz and 50 GHz.

The invention discloses preparation and application of a protein composite imprinting material for targeted recognition of strigolactones. The method comprises the following steps: 1, fusing halogenated alkane dehalogenase into ShHTL7 for induced expression to obtain recombinant protein; 2, preparing nano magnetic ferroferric oxide hollow microspheres; 3, carrying out surface amination modification on the nano magnetic ferroferric oxide hollow microspheres; 4, functionalizing halogenated alkanoic acid on the surfaces of the nano magnetic ferroferric oxide hollow microspheres subjected to amination modification; and 5, preparing the strigolactones surface protein molecularly imprinted polymer. The protein composite imprinting material which is high in adsorption efficiency, high in adsorption selectivity and capable of being rapidly enriched is prepared, shows superparamagnetism, can be rapidly separated under the action of a magnet, shows ultrahigh targeted recognition capacity on strigolactones, can be used for targeted extraction of strigolactones in parasitic plant root exudates, and has a good application prospect. The materials are convenient and fast to recycle and can be repeatedly used.

The invention discloses a difunctional nanoparticle and a construction method thereof in the technical field of biosensors. The nanoparticle comprises a ferroferric oxide magnetic core, a mesoporous silicon dioxide shell layer coated on the surface of the magnetic core, palladium nanoparticles modified on the surface of the silicon dioxide shell layer, and luminol molecules coupled to the silicon dioxide shell layer through covalent bonds. The material has superparamagnetism, a high specific surface area, a mesoporous structure and efficient peroxide activity, can accelerate hydrogen peroxide to generate hydroxyl radicals (OH), and can promote luminol to generate strong electrochemiluminescence signals. The superparamagnetism can be used as a trapping agent for trapping exosomes in body fluid. The PD-L1-modified gold electrode is combined with the exosome-nanoparticle compound, so that the PD-L1 exosome can be sensitively and quickly detected, and the PD-L1-modified gold electrode has important significance in early discovery of non-small cell lung cancer and prediction of the treatment effect of an immune checkpoint inhibitor.

The application discloses a tree-shaped heavy oil demulsifier with magnetic response, a preparation method and application thereof. The demulsifier comprises composite magnetic nano-particles, the composite magnetic nano-particles have a magnetic particle core and a polymer coated on the outer surface of the magnetic particle core, the magnetic particle core is modified superparamagnetic ferroferric oxide nano-particles, and the polymer is alkyl phenol formaldehyde resin polyoxyethylene polyoxypropylene ether. The application successfully realizes quick demulsification of emulsion under the action of magnetic response at low temperature, the amount of the magnetic particles is small during demulsification, and the demulsification process is environment-friendly, efficient and low in cost.

The invention relates to a magnetic field sensor (15) for measuring a differential current, intended to withstand a magnetic field to be measured generated by the induction of a current flowing through at least two primary conductors, at least a portion of which extends according to an axis (Z), said current flowing through at least one primary conductor (4a) in a forward direction according to said axis (Z), and flows through at least one of the primary conductors (4b) in a reverse direction opposite to the forward direction. The sensor is characterized in that it comprises: an inner magnetic circuit (16) configured to form a closed profile around the primary conductor; an outer magnetic circuit (17) surrounding the inner magnetic circuit (16); at least one SPM superparamagnetic material coil (18) arranged between the inner magnetic circuit (16) and the outer magnetic circuit (17).

The invention discloses a multifunctional magnetic carbon quantum dot sensor, a preparation method and application, and aims to solve the technical problems of detection and synchronous separation and recovery of Al < 3 + > in a water body. The sensor is formed by carrying out electrostatic self-assembly loading on aminated ZnFe2O4 (at) SiO2 nanoparticles and carbon quantum dots with carboxyl and hydroxyl on the surfaces, and has a core-shell structure and superparamagnetism. The preparation process comprises three steps of carbon quantum dot hydrothermal synthesis, ZnFe2O4 coated SiO2 nanoparticle coating and amino modification, and electrostatic self-assembly compounding, and the process is simple and easy to control. The sensor has specific recognition capability on Al, is excellent in anti-interference performance, can realize rapid magnetic separation by virtue of self magnetism, does not need centrifugation or filtration assistance, can be recycled after elution, and can avoid secondary pollution. Detection and adsorption separation of Al < 3 + > are synchronously achieved, the green chemistry concept is met, and the method has important application value in the fields of wastewater treatment and aluminum resource recovery.

The application discloses a kind of selective removal of divalent mercury in smelting waste acid The preparation method of magnetic adsorbent belongs to the technical field of divalent mercury removal in smelting waste acid.The adsorbent described in the application is formed by loading copper sulfide (CuS) on Fe-Ti spinel by passing hydrogen sulfide gas into the mixed solution of Fe-Ti spinel (Fe-Ti spinel) and copper sulfate, and then calcining under nitrogen protection. The application significantly improves the ability of CuS / Fe-Ti spinel to remove divalent mercury by means of calcining under nitrogen protection. At the same time, the adsorbent has excellent selectivity for the removal of divalent mercury. In addition, the adsorbent has superparamagnetism and can be easily separated from smelting waste acid by an external magnetic field, making it easy to safely dispose of the mercury-containing adsorbent.