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14878results about How to "Small particle size" patented technology

Matrix compositions for controlled delivery of drug substances

A novel matrix composition for pharmaceutical use. The matrix composition has been designed so that it is especially suitable in those situation where an improved bioavailability is desired and / or in those situation where a slightly or insoluble active substance is employed. Accordingly, a controlled release pharmaceutical composition for oral use is provided in the form of a coated matrix composition, the matrix composition comprising i) a mixture of a first and a second polymer that have plasticizing properties and which have melting points or melting intervals of a temperature of at the most 200° C., the first polymer being selected from the group consisting of polyethylene glycols and polyethylene oxides, and the second polymer being selected form block copolymer of ethylene oxide and propylene oxide including poly(ethylene-glycol-b-(DL-lactic acid-co-glycolic acid)-b-ethylene glycol (PEG-PLGA PEG), poly((DL-lactic acid-co-glycolic acid)-g-ethylene glycol) (PLGA-g-PEG), poloxamers and polyethylene oxide-polypropylene oxide (PEO-PPO), ii) a therapeutically, prophylactically and / or diagnostically active substance, the matrix composition being provided with a coating having at least one opening exposing at one surface of said matrix, wherein the active substance is released with a substantially zero order release.
Owner:EGALET LTD

Organic material based uniprill fertilizer

An organic-based uniprill fertilizer is provided. To produce the fertilizer, organic matter is sequentially pre-treated by first mixing it in a first grinder with a lime admixture, then adding a slurry of reagents and binders, followed by a mixture of acids. The acids can include sulfuric and phosphoric acids, in addition to nitric acid and various organic acids such as citric and fulvic acid, depending on the end requirements of the fertilizer product. Following the mixing of the pre-product with the mixture of acids and reagents, the resultant raw product is preferably processed through a second grinder. This grinding further dries, mixes and granulates the raw product. The particle size of the completed fertilizer is reduced into a flowable, user safe uniprill product that can be further ground to reduce its moisture. Further drying may be necessary for bag or bulk product, or it can be liquified by high speed blending or micro-fluidized for sprinkler or drip applications. The uniprill fertilizer comprises small, preferably microscopic particles that are homogenous in nature, in that any single particle is substantially identical in composition to all other particles of the fertilizer. Additionally, each uniprill particle contains substantially all sixteen nutriments and minerals required for the growth of healthy plants.
Owner:GREEN TRIANGLE
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