107results about How to "High magnetic responsiveness" patented technology

The invention belongs to the technical field of functional materials and particularly relates to covalent organic frame magnetic composite microspheres of core-shell structure and a preparation method of microspheres. Cores of the core-shell type composite microspheres are ferroferric oxide magnetic particles, and shells are covalent organic frames of ordered porous structures. The preparation method includes the steps that the ferroferric oxide magnetic particles are prepared through the solvothermal method; core-shell type magnetic composite microspheres are obtained through aldimine condensation reaction; under the solvothermal condition, the core-shell type magnetic composite microspheres in a formless and disordered channel state are induced to be converted into highly crystallized covalent organic frames with ordered channels, and the covalent organic frame magnetic composite microspheres with the excellent porous property are obtained. The composite microspheres have the advantages of being uniform in size, high in dispersity, high in mangnetic responsiveness, high and ordered in porosity and the like. The preparation method is simple, the process is controllable, and the size and the appearance of the composite microspheres are kept unchanged. The composite microspheres and the preparation method have wide application prospects in the fields of catalysis, drug loading, molecular sensing, energy storage and the like.

The invention belongs to the technical field of functional material and particularly relates to a magnetic mesoporous titanium dioxide core-shell type compound microsphere as well as a preparation method and applications thereof. The core-shell type compound microsphere takes a ferroferric oxide nano particle cluster as the core and takes mesoporous titanium dioxide with high crystallinity as the shell. The preparation method comprises the following steps: firstly, preparing the ferroferric oxide nano particle cluster with stable citric acid, secondly, wrapping the surface of the cluster with an amorphous titanium dioxide shell through a sol-gel method, and finally, obtaining the magnetic mesoporous titanium dioxide core-shell type compound microsphere through hydro-thermal treatment. By being provided with the mesoporous titanium dioxide shell with high crystallinity, the compound microsphere has the characteristics of high selectivity, high enrichment capacity, high sensitivity and high recovery rate to phosphoeptide; and since a magnetic core exists, the microsphere enriched in phosphoeptide can be separated by magnetism quickly and very conveniently. The method provided by the invention has the advantages that the operation is simple, the process is controllable, and the prepared compound microsphere can be used for analyzing and identifying phosphoeptide with ultra low concentration in a biological sample.

The invention discloses a reduction-oxidation graphene-Fe3O4 nano composite, a preparation method thereof, and an application of the reduction-oxidation graphene-Fe3O4 nano composite in absorbing bisphenol A. The reduction-oxidation graphene-Fe3O4 nano composite comprises Fe3O4 nano particles and reduction-oxidation graphene. The reduction-oxidation graphene-Fe3O4 nano composite and a solution containing the bisphenol A are in full contact in an ambient temperature, the bisphenol A is absorbed and removed. Compared with the prior art, the advantages of small material dose, simplicity in operation, mild processing condition, fast processing speed, and no harm for the environment, and recycling nano-composite materials, and the like are achieved.

The invention discloses a magnetic covalent organic frame material and a preparation method and an application thereof. The magnetic covalent organic frame material takes piperazine and cyanuric chloride as the construction units to form a covalent organic frame, and then the covalent organic frame is loaded on the organic frame material formed on the surface of magnetic ferriferrous oxide. The organic frame material better solves the problems of small particle size, poor stability and difficult separating from a water body of the current covalent organic frame materials. The method employs a solvothermal method, and akes the magnetic ferriferrous oxide nano particles as a carrier, the material is immersed into a piperazine-containing ligand solution, a cyanuric chloride ligand solution is dropped, and a hydro-thermal reaction is carried out under constant temperature condition to obtain the magnetic covalent organic frame material. The material has the characteristics of strong separating capability in water, large adsorption quantity on pollutants in the water body, high mechanical strength and environmental friendliness.

The invention provides a preparation method and an application of a core-shell magnetic composite microsphere capable of separating glycoprotein. The preparation method is characterized in that a core of the core-shell magnetic composite microsphere is a magnetic iron oxide black nanoparticle cluster and a shell is a crosslinked polymer network rich in carboxyl, then carboxyl and aminobenzene boron ester carry out amidation to carry out surface modification, and glycoprotein can be quickly separated and enriched under the physiological conditions via plenty of surface immobilized boron esters. The preparation method comprises the following steps of: firstly preparing a magnetic nanoparticle cluster with stable sodium citrate, secondly adopting a sol-gel method to modify the surface of the magnetic cluster with active vinyl functional groups, thirdly preparing high-magnetic-responsiveness monodispersed core-shell magnetic polymer composite microsphere rich in carboxyl on the surface via reflux precipitation polymerization, fourthly carrying out amidation on aminobenzene boron ester and carboxyl to modify the surface of the core-shell magnetic composite microsphere with plenty of boron ester groups and finally carrying out separation and enrichment on glycoprotein. The method provided by the invention is simple, is controllable in process, has higher glycoprotein separation and purification efficiency and can carry out separation and enrichment under the physiological conditions.

The invention provides a magnetic copper and bismuth catalyst and a preparation method of the magnetic copper and bismuth catalyst. The catalyst uses Fe3O4-MgO-SiO2 as a carrier, wherein the content of CuO is 20-40 wt%, the content of Bi2O3 is 1-5 wt%, the content of Fe3O4 is 8-30 wt%, the content of SiO2 is 20-46 wt%, and the content of MgO is 2-25 wt%. The preparation method comprises the following steps: placing a mixed solution consisting of a trivalent iron salt, glycol and sodium acetate in a hydrothermal kettle, reacting to obtain Fe3O4; preparing a mixed water solution containing a copper salt, a bismuth salt and a magnesium salt; ultrasonically dispersing the prepared Fe3O4 in an ethanol solution of an organic silicon source to form a turbid liquid; dropwise adding the prepared mixed solution in the turbid liquid; adjusting the pH value by using an alkali liquor to obtain a mixed precipitate, centrifuging, washing, further ageing, washing, drying and roasting in an inert atmosphere to obtain the catalyst. The catalyst is applied to the reaction of synthesizing 1,4-butynediol through ethinylation of formaldehyde, has high catalytic activity and selectivity, and can be effectively separated under the action of an applied magnetic field.

The invention discloses a method and a device for purifying water by means of strong magnetic separation-magnetic biomass charcoal absorption. The method combines a strong magnetic separation technology and a magnetic seed absorption technology, and adopts micron-scale superparamagnetic biomass charcoal as a magnetic seed; due to a reticular structure of chitosan magnetic particles loaded on the surface of the magnetic biomass charcoal, the specific surface area of the magnetic biomass charcoal is enlarged, and pollutants are facilitated to be absorbed; furthermore, the magnetic particles in the magnetic biomass charcoal exist in a form of a stable Fe3O4 crystalline state and have superparamagnetism, so that the magnetic biomass charcoal has a better absorption effect. The invention further optimizes a traditional strong magnetic separation system and simplifies recovery equipment, thus greatly reducing the adding amount of a coagulant and the energy consumption of treatment, and lowering the recycling cost of the magnetic seed.

The invention provides a method for compositing a Fe3O4 nanorod structure through a gas-liquid interface under the magnetic induction. The method comprises the following steps of: introducing ammonia into a solution dissolved with iron ions and ferrous ions under the regulation of an external magnetic field, and standing for 70-90 minutes at the temperature of 55-75 DEG C until a black brown sediment appears in the solution; and cooling to room temperature, washing with distilled water and alcohol respectively, vacuum-drying, and obtaining a Fe3O4 nanorod with the length of the namorod structure being 30-120 nm. The magnetism of the Fe3O4 nanorod structure can be analyzed and discovered by using a vibrating sample magnetometer, the residual magnetism and a coercive force of the Fe3O4 nanorod structure both can be omitted under the condition without the external magnetic field, the saturation magnetization is 75-80 emu/g, and the superparamagnetism is expressed at the room temperature; and simultaneously, the Fe3O4 nanorod structure also has a higher magnetic responsibility and has a potential application prospect in fields of targeted therapy and shielding.

The invention provides a method for preparing Fe3O4 nanorods in a gradient magnetic field, which comprises the following steps: under the action of a gradient magnetic field, dropwisely adding a solution containing iron ions and ferrous ions into a reactor charged with ammonia gas, and reacting at 80-90 DEG C for 40-50 minutes; separating a black precipitate from the solution; and cooling to room temperature, respectively washing with distilled water and ethanol, and carrying out vacuum drying to obtain the Fe3O4 nanorods. The scanning electron microscope, transmission electron microscope, X-ray diffraction and other analyses indicate that the prepared Fe3O4 nanorods have the advantages of regular and orderly structure, complete crystals and uniform morphology, the diameters are 35-45nm, and the lengths are 300-400nm; the analysis on the magnetic properties of the product at room temperature detects that the magnetic remanence and coercive force of the product can be neglected, the saturation magnetization is 54-86 emu/g, and thus, the product appears superparamagnetism; and the magnetic response analysis illustrates that the Fe3O4 nanorods also have high magnetic response, and such characteristic has great potential application prospects in the fields of drug delivery systems and catalysis.

The invention discloses a preparation method of core-shell magnetic conductive polymer microspheres. Ferrite (Fe3O4, gamma-Fe2O3, MFe2O4; M = Fe, Co, Ni, Mn and the like) nano or micro spherical or near-spherical particles are used as cores; firstly, surface hydroxyl protonation is performed on the magnetic cores to fully combine the magnetic cores before compositing with monomer molecules by the electrostatic interaction and hydrogen-bond action between the protonated hydroxy and monomer aniline, pyrrole or derivatives thereof; and in the oxidation polymerization process, the monomer molecules are controlled to form cores and grow on the surfaces of the magnetic cores, thereby preparing the core-shell magnetic conductive polymer microspheres with high magnetic responsibility and good dispersity. By the characteristics that the amido-containing magnetic polymer microspheres are positively charged in a high-pH solution while the DNA molecules in a tissue or cell lysis solution are negatively charged, the prepared magnetic composite microspheres are applied to DNA separation and purification assisted by an external magnetic field.

The invention provides a method for preparing a catalyst for catalyzing oxidation of cyclohexane. The method comprises steps as follows: (A), preparing 5 (p-propionate) phenyl-10,15,20-tri(pyridyl) porphyrin; (B), preparing 5(p-hydroxy) phenyl-10,15,20-tri(pyridyl) porphyrin from 5 (p-propionate) phenyl-10,15,20-tri(pyridyl) porphyrin; (C), preparing metallic coordinated 5-(p-hydroxy) phenyl-10,15,20-tri(pyridyl) porphyrin from 5 (p-hydroxy) phenyl-10,15,20-tri(pyridyl) porphyrin; (D), attaching the metallic coordinated 5-(p-hydroxy) phenyl-10,15,20-tri(pyridyl) porphyrin to at least one magnetic microsphere, and methylating 5-(p-hydroxy) phenyl-10,15,20-tri(pyridyl) porphyrin by the aid of methyl iodide.

The invention discloses a preparation method of a core-shell type boryl magnetic microsphere capable of greatly enriching glycoprotein. The preparation method comprises the following steps: taking ferric trichloride hexahydrate and acetate as raw materials, adopting a solvothermal method to prepare nano ferroferric oxide magnetic particles; adopting a sol-gel method to surface a layer of SiO2 on the surfaces of the nano ferroferric oxide magnetic particles; modifying the magnetic microsphere coated with SiO2, and enabling the surface of the magnetic microsphere to obtain an active vinyl functional group; preparing the core-shell type boryl magnetic microsphere with amino rich in surface through polymerization reaction; modifying a great number of borate groups by the amino in the surface and carboxybenzene borate through amidation reaction, thereby obtaining the core-shell type boryl magnetic microsphere. The core-shell type boryl magnetic microsphere prepared by the preparation methodis uniform in particle diameter distribution, is regular in structure, is controllable in magnetic content, has the characteristics of high magnetic response and surface modification, can separate and purify glycoprotein under a physiological condition, is good in separating ability, and is a biological magnetic separating material with application prospect.

The invention discloses a hollow magnetic polymer composite microsphere. The hollow magnetic polymer composite microsphere sequentially comprises an inner cavity, a polymer inner shell and a superparamagnetic nano-particle outer shell from inside to outside, and a large number of superparamagnetic nano-particles are tightly packed to form the superparamagnetic nano-particle outer shell. The composite microsphere is normalized in shape and narrow in size distribution, has high saturation magnetization, and is long in storage time and beneficial to popularization and application in the biomedicine field. The composite microsphere is synthesized by improved O/W emulsified solvents through a volatilization method, the superparamagnetic nano-particles serve as reactants to participate in the reaction and also serve as particle emulgators to stabilize the emulsification system, use of a large number of surface active agents is avoided, and the hollow magnetic polymer composite microsphere is easy to operate and convenient to popularize.

The invention discloses a preparation method of a silicon hydroxyl magnetic bead. The preparation method comprises the following steps that ferric trichloride, trisodium citrate, sodium acetate and polyhydric alcohol are mixed evenly to obtain a mixed solution, and Fe3O4 nanoparticles are prepared by a solvothermal method; and the surface of the Fe3O4 nanoparticles is coated with SiO2 films by atomic layer deposition to obtain the silicon hydroxyl magnetic bead. The Fe3O4 nanoparticles prepared by the solvothermal method are coated with the SiO2 films by atomic layer deposition (ALD), the SiO2films are plated on the surface of the Fe3O4 nanoparticles in the form of a monatomic film, the SiO2 films laminated by the method can grow at a constant speed on the surface and at defects of the Fe3O4 nanoparticles, the SiO2 films on the surface are a whole after coating, and the coating compactness of the SiO2 films on Fe3O4 is good and the SiO2 films are not prone to falling off, therefore, coating defects on the surface of the magnetic bead can be prevented from being generated. In addition, by adjusting the deposition conditions and the number of cycles, the thickness of the SiO2 filmscan be precisely controlled, the process is simple, operation can be standardized, no complicated operation is required, errors are small, and later screening of the magnetic bead is avoided, so thatthe purpose of improving the product quality and the stability of magnetic bead batches is achieved.

The invention belongs to the field of material technology and micro-nano manufacturing, and relates to a functionalized biological hybrid micro-nano motor and a preparation method thereof. The functionalized biological hybrid micro-nano motor comprises a biological entity inner core, a magnetic nanoparticle coating and a probe layer. According to the invention, fungal spores, pollen and micro/nano-scale plant seeds are selected as the inner core, so that the inner core is easy to obtain or massively culture, and the material is uniform in size and easy to control; and the inner core and the nano-particles are hybridized through a step-by-step coating method, and a probe is loaded on the surface of the nano-coating. The functionalized biological hybrid micro-nano motor can actively move under accurate control, is very easy to observe, and overcomes the defects in the prior art.

Belonging to the field of wet metallurgy, the invention provides a selective separation method of gold ions. The method includes: adding Fe3O4/SiO2/cPPyTh magnetic nano compound into an aqueous solution containing gold ions, fully stirring the substances at room temperature, and conducting magnetic separation to obtain a gold ion adsorbing magnetic nano compound; and then adding the obtained gold ion adsorbing magnetic nano compound into a mixed solution of thiourea and hydrochloric acid, performing stirring at room temperature, and eluting the gold ions adsorbed on the surface of the magnetic nano compound. The unit equilibrium adsorption capacity is high to 816.3mg/g; the separation efficiency is high, the adsorption capacity within 5min is up to 496.7mg/g; adsorption of gold ions can be carried out spontaneously at room temperature; under the condition of coexistence of a variety of interfering ions (Mg<2+>, Cu<2+>, Zn<2+>, As<5+>, Cd<2+> and Pb<2+>), relative to each interfering ion, the average adsorption selectivity of Fe3O4/SiO2/cPPyTh to gold ions is higher than 4; the reusability is good, and after continuous use for 5 times, the adsorption/recovery rate of gold ions reaches 93.3%/92.3%.

The invention belongs to the technical field of enzyme purification and immobilization, and more specifically relates to a curdlan-based protein purifying/immobilizing difunctional ion chelated magnetic carrier, and applications thereof. The difunctional ion chelated magnetic carrier is obtained via activation and chelating of magnetic curdlan microspheres, and possesses immobilizing and purifyingfunctions; according to magnetic curdlan microspheres, Fe3O4 nanoparticles are taken as a core, a shell is obtained via curdlan reverse embedding, and the difunctional ion chelated magnetic carrier is obtained via synthesis. The difunctional ion chelated magnetic carrier possesses magnetic responsibility; in applications, column separation is not needed, separation of the difunctional ion chelated magnetic carrier from a reaction system can be realized easily under the action of an applied magnetic field, and one-step elution and recycling can be realized rapidly and conveniently. The difunctional ion chelated magnetic carrier is capable of playing an important role in the fields such as enzyme immobilization and enzyme purification because applications are convenient and high in efficiency; the stability and catalytic efficiency of xylanase obtained via immobilization using the difunctional ion chelated magnetic carrier are increased obviously, production cost is reduced, and large scale industrialized production is promising to realize.