14826results about How to "Increase surface area" patented technology

A bioprosthetic device is provided for soft tissue attachment, reinforcement, and or reconstruction. The device comprises a naturally occurring extracellular matrix portion and a three-dimensional synthetic portion. In illustrated embodiments, the naturally occurring extracellular matrix portion comprises layers of small intestine submucosa, and the three-dimensional synthetic portion comprises a foam or a three-dimensional mesh, textile, or felt.

A method for manufacturing a porous ceramic scaffold having an organic / inorganic hybrid coating layer containing a bioactive factor includes (a) forming a porous ceramic scaffold; (b) mixing a silica xerogel and a physiologically active organic substance in a volumetric ratio ranging from 30:70 to 90:10 and treating by a sol gel method to prepare an organic / inorganic hybrid composite solution; (c) adding a bioactive factor to the organic / inorganic hybrid composite solution and agitating until gelation occurs; and (d) coating the porous ceramic scaffold with the organic / inorganic composite containing the bioactive factor added thereto. In accordance with the method, the porous ceramic scaffold may be uniformly coated with the organic / inorganic hybrid composite while maintaining an open pore structure, and stably discharge the bioactive factor over a long period of time.

A surgical instrument particularly suited to endoscopic and laparoscopic insertion through a cannula of a trocar into an insufflated body cavity or lumen includes a bending member in an elongate shaft that acts to rotate an end effector about an articulation pivot joint. A proximally directed camming surface (e.g., gear segment, cam recess) aft of a pivotal attachment of the end effector to a proximal frame ground of the elongate shaft interacts with a bending member whose proximal end is ground to the proximal frame ground. Differential fluidic actuators or mechanical cam bars deflect a distal end (e.g., rack, cam point) of the bending member to effect articulation. Thereby, the end effector may act upon tissue that would otherwise be obscured, such as behind an organ. The articulated end effector also advantageously allows an endoscope to be positioned behind the end effector without being blocked by the instrument shaft.

Apparatus and methods for ablating, severing, cutting, shrinking, coagulating, or otherwise modifying a target tissue to be treated. In a method for treating a target tissue, an active electrode of an electrosurgical probe is positioned in at least close proximity to the target tissue in the presence of an electrically conductive fluid. A high frequency voltage is then applied between the active electrode and a return electrode, wherein, the high frequency voltage is sufficient to volumetrically remove (ablate), sever, or modify at least a portion of the target tissue. The probe comprises a multi-lumen shaft having a plurality of internal lumens, and a return electrode coil oriented substantially parallel to the shaft distal end. The active electrode may be in the form of a metal disc, a hook, or an active electrode coil. In the latter embodiment, the active electrode coil is typically arranged substantially orthogonal to the return electrode coil. Methods of making an active electrode coil, a return electrode coil, and an electrosurgical probe are also disclosed.

A catheter includes a sealed multi-lumen heat transfer extension designed to internally circulate a coolant, and thereby cool tissue or fluid surrounding the catheter. The heat transfer extension includes a tube having a distally positioned region that coils about the tube's longitudinal axis. The tube houses multiple lumens running longitudinally along the tube. These lumens include one or more supply lumens and one or more return lumens. A distal fluid exchange reservoir resides at the tube's tip, for the purpose of redirecting fluid from the supply lumen(s) to the return lumen(s). The heat transfer extension may include a shape memory structure causing the heat transfer extension to vary its shape according to temperature. Namely, the extension assumes a coiled shape under predetermined shape-active temperatures, and it assumes a non-coiled shape under other predetermined shape-relaxed temperatures. The catheter also includes an interface having supply and return lines to provide coolant to the heat transfer extension, and remove coolant returning therefrom. To connect the supply / return lines with the supply / return lumens, the invention may include a fluid transfer housing. Optionally, one or more of the lumens may be configured as flow-through lumens to exchange fluids with the patient.

A linearly expanding spine cage has a minimized diameter in its unexpanded state that is equal to the diameter of an insertion groove cut into adjacent vertebral bodies. The cage conformably engages between the endplates of adjacent vertebrae to effectively distract the disc space, widen neuroforamina, stabilize the motion segments and eliminate pathologic spine motion. Angular deformities can be corrected, and natural curvatures maintained. The cage enhances spinal arthrodesis by creating a rigid spine segment. Expanding linearly (vertically, along the vertical axis of the adjacent spine) rather than uniformly, the cage height increases and holds the vertebrae with fixation forces greater than adjacent bone and soft tissue failure forces. Stability is thus achieved immediately, enabling patient function by eliminating painful motion. The cage width remains stable, so as to decrease impingement upon a second cage, or upon soft tissue structures in the immediate vicinity, including neural or vascular elements.

This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates, as well as methods and uses for such substrates.

A system to promote the healing of an exuding wound includes a wound dressing, a subatmospheric pressure mechanism, and a collection canister. The wound dressing is dimensioned for positioning relative to a wound bed of a subject. The subatmospheric pressure mechanism includes a control unit disposed within a housing. The control unit includes a vacuum source associated with a vacuum port. The collection canister has an interior wall which defines an internal chamber. The internal chamber is in fluid communication with the vacuum source of the subatmospheric pressure mechanism through the vacuum port and with the wound dressing for collecting exudates removed for the wound bed under influence of the vacuum source. The canister including a baffle mechanism disposed within the internal chamber for dampening the movement of the collected exudates.

An apparatus and method for electrospinning polymer fibers and membranes. The method includes electrospinning a polymer fiber from a conducting fluid in the presence of a first electric field established between a conducting fluid introduction device and a ground source and modifying the first electric field with a second electric field to form a jet stream of the conducting fluid. The method also includes electrically controlling the flow characteristics of the jet stream, forming a plurality of electrospinning jet streams and independently controlling the flow characteristics of at least one of the jet streams. The apparatus for electrospinning includes a conducting fluid introduction device containing a plurality of electrospinning spinnerets, a ground member positioned adjacent to the spinnerets, a support member disposed between the spinnerets and the ground member and movable to receive fibers formed from the conducting fluid, and a component for controlling the flow characteristics of conducting fluid from at least one spinneret independently from another spinneret.

A double sliding-type portable communication apparatus, in which one housing slidably moves relative to the other housing through double-sliding motions, which includes a main housing extending in a longitudinal axis and a sliding housing moving in said longitudinal and also lateral directions across the main housing whose upper surface faces away from the main housing to allow the sliding housing may become displaced away from the main housing and also slidably return to overlap the main housing, wherein said housings are aligned parallel to each other in the longitudinal axis or a lateral direction across the main housing to expose predetermined regions of an upper surface of the main housing with keys provided thereon.

The present invention includes an intervertebral prosthetic disc, a method for installing a plate into an intervertebral space, and a method for installing a prosthetic disc into an intervertebral space. The intervertebral prosthetic disc can include a superior endplate and an inferior endplate, wherein at least one of the superior endplate and the inferior endplate is adapted to receive a guidewire. In the methods for installing a plate into an intervertebral space and for installing a prosthetic disc into an intervertebral space, a guidewire is used to facilitate installing plates onto vertebral bone endplates.

An identification tag and related tag system are provided for securely mounting the identification tag onto a selected wearer or object, such as mounting onto a wearer's wrist or the like. The identification tag is adapted to receive wearer-related identification and other information in human readable and / or machine readable form, and for slide-fit assembly onto an elongated flexible strap such as a wristband or bracelet for mounting onto the selected wearer or object. In one preferred form, the identification tag includes a radio frequency identification (RFID) circuit adapted for communicating wearer-related information with a remote reader. The tag system, including the identification tag assembled with the flexible strap, is particularly useful with a small wearer or object, such as an infant, to provided a relatively extensive and relatively flat information-bearing surface area.

A bone fusion device provides stability to bones during a bone fusion period. The bones include, for example, the vertebrae of a spinal column. The bone fusion device comprises one or more extendable tabs attached to the bone fusion device by associated rotating means. The bone fusion device is preferably inserted by using an arthroscopic surgical procedure. During arthroscopic insertion of the device, the tabs are pre-configured for compactness. In this compact configuration, the tabs are preferably deposed along and / or within an exterior surface of the bone fusion device. After the bone fusion device has been positioned between the bones, one or more tab(s) are extended. In the preferred embodiment, the position of each tab is related to a positioning element and an extending block. Typically, the tabs advantageously position and brace the bone fusion device in the confined space between the bones until the bones have fused.

A touch screen in the form of a panel is capable of conducting signals and a tomograph including signal flow ports is positioned adjacent the panel with the signal flow ports arrayed around the border of the panel at discrete locations. Signals are introduced into the panel to pass from each discrete border location to a plurality of other discrete border locations for being detected and tomographically processed to determine if any change occurred to signals due to the panel being touched during signal passage through the panel, and therefrom determine any local area on the panel where a change occurred. The tomograph computes and outputs a signal indicative of a panel touch and location, which can be shown on a display.

A system and method for spinal fusion comprising a spinal fusion implant of non-bone construction releasably coupled to an insertion instrument dimensioned to introduce the spinal fusion implant into any of a variety of spinal target sites.

The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter is inserted through an incision into a large blood vessel of a patient. By selectively heating or cooling a portion of the catheter lying within the blood vessel, heat may be transferred to or from blood flowing within the vessel and the patient's body temperature may thereby be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia and hyperthermia, or for inducing a condition of artificial hypothermia when desired.

An auto-injector for dispensing a predetermined dose of medicament is disclosed. The auto-injector includes a needle cover that is configured to move from a retracted position to an extended locked position. The auto-injector includes a first locking assembly to hold the needle cover in a locked retracted position and a second locking assembly to hold the needle cover in a locked extended position.

The present invention concerns a method and an apparatus for removing substances from gases discharged from gas phase reactors. In particular, the invention provides a method for removing substances contained in gases discharged from an ALD reaction process, comprising contacting the gases with a “sacrificial” material having a high surface area kept at essentially the same conditions as those prevailing during the gas phase reaction process. The sacrificial material is thus subjected to surface reactions with the substances contained in the gases to form a reaction product on the surface of the sacrificial material and to remove the substances from the gases. The present invention diminishes the amount of waste produced in the gas phase process and reduces wear on the equipment.

The present invention includes intervertebral prosthetic devices and methods for installing intervertebral prosthetic devices into an intervertebral space. In one embodiment, an intervertebral prosthetic disc includes a superior endplate; an inferior endplate; and at least one protrusion element, wherein at least one of the superior endplate and the inferior endplate is adapted to receive the protrusion element. In another embodiment, the invention includes an intervertebral prosthetic disc having a superior endplate including a core retaining member; an inferior endplate including a core retaining member; and an asymmetric core positioned between the superior endplate and the inferior endplate, wherein the superior endplate and the inferior endplate are adapted to accommodate the core. The present invention also includes an intervertebral prosthetic disc system that includes an intervertebral prosthetic disc and at least one spring element.

A method for producing hydrogen gas is provided and comprises reducing a metal oxide in a reduction reaction between a carbon-based fuel and a metal oxide to provide a reduced metal or metal oxide having a lower oxidation state, and oxidizing the reduced metal or metal oxide to produce hydrogen and a metal oxide having a higher oxidation state. The metal or metal oxide is provided in the form of a porous composite of a ceramic material containing the metal or metal oxide. The porous composite may comprise either a monolith, pellets, or particles.

This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, a method of administering a composition to a patient is disclosed which comprises providing a composition-eluting device, said composition-eluting device comprising at least a first surface and a plurality of nanostructures attached to the first surface, and introducing the composition-eluting device into the body of the patient.

A high strength porous polymeric material manufactured by a compression process is disclosed. The material results in a network of interconnected collapsed pores, which forces thin overlapping walls and passages to be created. The network provides permeable access for fluid migration throughout the material. The strength and / or permeability are advantageous for medical devices and implants.

The invention relates to an apparatus and process for the vaporization of liquid precursors and deposition of a film on a suitable substrate. Particularly contemplated is an apparatus and process for the deposition of a metal-oxide film, such as a barium, strontium, titanium oxide (BST) film, on a silicon wafer to make integrated circuit capacitors useful in high capacity dynamic memory modules.

Systems and methods are provided for performing electrosurgical interventions, such as selectively contracting soft collagen tissue and other body structures, while limiting thermal damage or molecular dissociation of such tissue and limiting the thermal damage to tissue adjacent to and underlying the treatment site. The systems and methods of the present invention are particularly useful for surgical procedures in electrically conducting environments, such as arthroscopic procedures in the joints, e.g., shoulder, knee, hip, hand, foot, elbow or the like. The present invention is also useful in relatively dry environments, such as treating and shaping the cornea, and dermatological procedures involving surface tissue contraction of tissue underlying the surface of the skin for tissue rejuvenation, wrinkle removal and the like.

This invention relates to an apparatus and method of drug delivery on a human body surface. The formulation comprises a drug, a conversion agent capable of converting the formulation from a less solid phase to a coherent, soft, solid phase, and a vehicle medium or carrier for the drug and conversion agent. The drug formulation is applied to this human body surface in its less than solid phase and is subsequently converted to a soft solid phase while the drug is being delivered through the human body surface. After delivery of the drug is complete, the soft solid formulation can be removed or peeled from the body surface as a coherent solid formulation. The drug formulation provides control over drug delivery rates and allows the formulation to be removed without leaving a messy, residual formulation on the body surface.

A golf club includes a golf club shaft and a golf club head connected to the golf club shaft. The golf club head includes a body having a forward surface and a striking member connected to the forward surface of the body. The striking member includes predetermined properties to deflect inwardly during initial contact with a golf ball and recover outwardly as the golf ball moves away substantially synchronized with compression and expansion of the golf ball. In some embodiments, the golf club head may include a spacer or neck connecting opposing medial portions of the body and the striking member. In other embodiments, the striking member may include a first layer and a second underlying layer disposed over the body.