1781results about How to "Change shape" patented technology

A device, a system and a method for treating heart valve regurgitation. The annulus reshaping device comprises a base and a plurality of legs radially arranged there upon. The device can transform from a delivery configuration wherein it is deliverable by catheter to a treatment site, into a deployment configuration, and then a treatment configuration for treating valvular regurgitation. The device is implanted into the annulus of a heart valve, and the legs of the device can be telescopically withdrawn to apply an inward force to the annulus. The system comprises a device slidably received within a catheter. The method of treatment comprises delivering a device to a treatment area, via catheter, releasing the device from the catheter, positioning the legs of the device on a valve annulus, and applying an inward force to the annulus to reduce the regurgitation.

Floorboards with a mechanical locking system that allows movement between the floorboards when they are joined to form a floating floor.

The invention features devices and methods for the enrichment of cells and other desired analytes by employing a magnetic field, alone or in conjunction with size-based separation. The devices and methods may be advantageously employed to enrich for rare cells, e.g., fetal cells or epithelial cells, present in a sample, e.g., maternal blood.

Apparatus (20) is provided for treating mitral valve regurgitation, including a band (30) having distal and proximal ends, the band (30) adapted to be placed: around between 90 and 270 degrees of a mitral valve (58), including around at least a portion of a posterior cusp (56) of the valve (58), in a space defined by (a) a ventricular wall (70), (b) a ventricular surface of the posterior cusp (56) in a vicinity of an annulus (60) of the mitral valve (58), and (c) a plurality of third-order chordae tendineae (74). The apparatus (20) further includes distal and proximal coupling elements (32, 34), coupled to the band (30) at the distal and proximal ends thereof, respectively, and adapted to be coupled to a first chorda tendinea and a second chorda tendinea, respectively, each of the first and second chordae tendineae selected from the group consisting of: one of the plurality of third-order chordae tendineae (74), and a first-order chorda tendinea that inserts on a commissural cusp (78) of the mitral valve (58). Additional embodiments are also described.

A surgical ligation clip capable of remote deployment through a catheter.

The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.

The invention is directed to an optical system (1). The optical system (1) has a housing (2) with an opening (3) extending through the housing (2) encompassing an in general constant volume (V). A membrane (6) with two or more membrane sections is arranged across the opening separating the volume (V) in a first and a second chamber (7, 8) filled with at least one fluid. The membrane is attached to an annular holding frame (9). An actuator is interconnected to the membrane (6) directly or indirectly to change the optical behaviour of the membrane.

Apparatus (20) is provided for treating mitral valve regurgitation, including a band (30) having distal and proximal ends, the band (30) adapted to be placed: around between 90 and 270 degrees of a mitral valve (58), including around at least a portion of a posterior cusp (56) of the valve (58), in a space defined by (a) a ventricular wall (70), (b) a ventricular surface of the posterior cusp (56) in a vicinity of an annulus (60) of the mitral valve (58), and (c) a plurality of third-order chordae tendineae (74). The apparatus (20) further includes distal and proximal coupling elements (32, 34), coupled to the band (30) at the distal and proximal ends thereof, respectively, and adapted to be coupled to a first chorda tendinea and a second chorda tendinea, respectively, each of the first and second chordae tendineae selected from the group consisting of: one of the plurality of third-order chordae tendineae (74), and a first-order chorda tendinea that inserts on a commissural cusp (78) of the mitral valve (58). Additional embodiments are also described.

The invention features a device for the deterministic separation of analytes coupled to a reservoir containing a reagent that alters a magnetic propert of the analyte. Exemplary methods include the enrichment of a sample in a desired analyte (e.g., using deterministic separation) or the alteration of a desired analyte in the device. The devices and methods may be advantageously employed to enrich for rare cells, e.g., fetal cells or epithelial cells, present in a sample, e.g., maternal blood.

An accommodating intraocular lens includes an optic portion, a haptic portion. The optic portion of the lens includes an actuator that deflects a lens element to alter the optical power of the lens responsive to forces applied to the haptic portion of the lens by contraction of the ciliary muscles and a secondary deflection mechanism. Movement of the lens element by the actuator causes the lens element to deform and the secondary deflection mechanism causes the lens to further deform.

A method and system are disclosed for the mapping of energy delivery devices to energy sources. Energy capable of affecting a measurable property of the system is delivered through the energy delivery devices from the energy sources. A change in a property when the energy is delivered is measured using measuring devices that are associated in a known way with the energy delivery devices. A profile of the change is compared to a profile of the energy output in order to determine which energy sources produce an output capable of affecting the property measurable by each measuring device and, because of the association between measuring devices and energy delivery devices, each energy delivery device.

A device, a system and a method for treating heart valve regurgitation. The annulus reshaping device comprises a base and a plurality of legs radially arranged there upon. The device can transform from a delivery configuration wherein it is deliverable by catheter to a treatment site, into a deployment configuration, and then a treatment configuration for treating valvular regurgitation. The device is implanted into the annulus of a heart valve, and the legs of the device can be telescopically withdrawn to apply an inward force to the annulus. The system comprises a device slidably received within a catheter. The method of treatment comprises delivering a device to a treatment area, via catheter, releasing the device from the catheter, positioning the legs of the device on a valve annulus, and applying an inward force to the annulus to reduce the regurgitation.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

Abstract of the DisclosureFloorboards with a mechanical locking system that allows movement between the floorboards when they are joined to form a floating floor.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

A system and method for performing spinal fusion using vertebral connecting rods constructed of a shape memory material, such as shape memory alloy. The connecting rod is cooled below its phase transition temperature, which is chosen to be just below body temperature, and is inserted through a curved guide tube previously inserted into the back of the patient. The guide tube is located so as to deliver the connecting rod at its desired location between the preinserted pedicle screw heads. The rod, being in its flexible state below the transition temperature, negotiates the curve and exits the guide tube in a straight form and parallel to the patient's spine. As it heats up to body temperature, it regains its original straight shape and its original rigidity, and is ready for connecting its associated vertebrae to each other.

Floorboards with a mechanical locking system that allows movement between the floorboards when they are joined to form a floating floor.

The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition, e.g., cancer, in a subject by analyzing a cellular sample from the subject.

A systems and methods for controlling temperature in a cryogenic device includes providing a device having a probe and a heater element. A distal region of the probe is engaged with the target region. Measuring and recording current temperature of a proximal region of the probe and time of the measurement is used to determine slope of a temperature curve defined by two points. The first point is defined by the current temperature and time of measurement and a second point is defined by a previous measurement of proximal region temperature and time of measurement. When the slope is less than a slope threshold value a treatment flag is activated, treatment start time is recorded and the proximal region is heated with the heater element. Heating is discontinued and the treatment flag is deactivated after elapsed treatment time exceeds a duration threshold value.

An object is to effectively cool down an electronic equipment which is face with height limitations and tends to readily increase in heat generation amount to thereby provide the reliability required. The interior of a chassis of a control unit is partitioned by a back board into a front side space and a rear side space. In the rear side space, two control modules are attached so that these are stacked up and down, while two fan modules and a single duct member are attached in the front side space. Each fan module has two fans as built therein. A cooling air stream or “wind” from each fan flows into the lower-side control module through the duct member and others, whereas a cooling wind from the other fan flows into the upper-side control module. Even when either one of the fan modules goes down during operation, it is still possible by using the remaining fan module to cool down the both control modules.

Floorboards with a mechanical locking system that allows movement between the floorboards when they are joined to form a floating floor.

The vision of an eye having an impaired lens is stored with an artificial lens implant. The method involves replacing the lens by a polymerizable material injected into the emptied lens capsule and thereby providing a new lens implant with a predetermined refractive value, while admitting the possibility of controlling and adjusting the refractive value of the eye during the surgical process.

An image projector comprises a plurality of flexible reflective analog modulators (FRAMs), an illumination optics for focusing at least one light source thereon, a conversion optics for converting the variations in divergence of the beams reflected therefrom into variations in intensity, and a scanning mechanism coupled to a projection optics for displaying an image, constructed of intensity modulated light dots or pixels, on a screen. FRAM curvatures, responsible for determining the divergence of the reflected beams, and ultimately the intensity of each pixel, are varied by an actuation voltage that can be modulated using waveforms that minimize the FRAM response times. For multicolor images, three laser light sources operating at different wavelengths are used in conjunction with three linear FRAM arrays.

Floorboards with a mechanical locking system that allows movement between the floorboards when they are joined to form a floating floor.

Polysiloxanes suitable for the preparation of intraocular lenses by a crosslinking reaction, having a specific gravity of greater than about 1.0, a refractive index suitable for restoring the refractive power of the natural crystalline lens and a viscosity suitable for injection through a standard cannula are provided. Moreover, injectable intraocular lens material based on these polysiloxanes and methods of preparing intraocular lenses by direct injection into the capsular bag of the eye are also disclosed.

A capacitive sensor having a first and a second polymeric conductor are embedded within a non conducting body, wherein the body maintains a fixed separation distance between the first and the second polymeric conductor. The body can include a non conducting web, wherein the web substantially precludes variation in the spacing of the polymeric conductors during use in the intended operating environment.

A method to improve light extraction efficiency of a light emitting element such as an electroluminescent element is disclosed. Over a substrate, a first electrode, a light emitting layer, and a second electrode are sequentially stacked. The first electrode is a reflective electrode. The second electrode is an electrode which transmits visible light, and light emitted from the light emitting layer is extracted from the second electrode. In contact with a surface of the second electrode, many fine particles are provided. The fine particles have a refractive index which is equal to or higher than that of the second electrode. Light which passes through the second electrode is scattered and refracted by the fine particles. Accordingly, the amount of light which is totally reflected at an interface between the second electrode and a gas is reduced, and light extraction efficiency is improved.