92 results about "Chordae tendineae" patented technology

An embodiment includes an artificial chordae tendineae system comprising: a first needle; a flexible first chord coupled to a proximal end portion of the first needle; a first proximal pledget coupled to a proximal end portion of the first chord; a first distal conduit coupled to the first chord between the first proximal pledget and the first needle; wherein: the first distal conduit includes first and second faces; one of the first and second faces includes a first aperture; a sidewall of the first conduit, located between the first and second faces, includes a sidewall aperture that does not directly connect to the first aperture; the sidewall aperture is configured to include a portion of the first chord when the first distal conduit is permanently implanted adjacent tissue but not when the first distal conduit is traversing the tissue before being permanently implanted adjacent the tissue.

A system and method of repairing a native chordae of a patient using an artificial chordae. The artificial chordae is inserted into the patient in a non-deployed configuration using a delivery system and is delivered to a desired position within the patient. An operator causes the artificial chordae to transition from the non-deployed configuration to a deployed configuration. The artificial chordae is anchored to a myocardium of the patient. The artificial chordae is attached to a leaflet of the native chordae at an attachment location and tuned to a desired tension.

A system for implanting a replacement heart valve at a native valve location between an atrium and a ventricle of a patient includes a replacement valve having an expandable frame and a plurality of prosthetic valve leaflets positioned within the expandable frame. A delivery device is provided for delivering the replacement heart valve to the native valve location. The delivery device includes an elongate inner tube having an inner retention ring for coupling to and end of the replacement heart valve and an outer support tube slidable over the inner retention ring for securing the replacement heart valve to the inner retention ring. The inner retention ring preferably includes slots for receiving struts of the expandable frame. The expandable frame preferably includes a plurality of anchors extending from the downstream portion in an upstream direction for extending between chordae and for placement outside of the native leaflets.

An implantable device or implant is configured to be positioned within anatomy such as a native heart valve to repair the valve. The implantable device or implant is configured to be attached to one or more portions of the anatomy or native heart valve, such as one or more portions thereof can be moved closer together. For example, native valve leaflets, chordae tendinea, papillary muscles, a leaflet cleft, etc. can be moved to prevent or inhibit regurgitant flow through the native valve.

A device for connecting artificial chordae tendineae to the leaflets of an atrioventricular valve, the device comprising: a neochord delivery system comprising a manipulable and pushable catheter that houses a neochord attached to a neochord puncture needle, the catheter being operable to push the puncture needle to puncture and pass the neochord through the papillary muscle of the ventricle; a retriever system comprising a catheter that houses a grasper that is operable to capture the neochord puncture needle after it passes through the papillary muscle and remove the neochord puncture needle and the neochord from the ventricle; and a tissue clamping system comprising a catheter that houses a distal tissue clamp and a proximal tissue clamp that can be deployed to clamp and hold the area of ​​the atrioventricular valve located therebetween so that the area can be punctured by the puncture needle to deliver the neochord through the leaflets and to the papillary muscle.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

The present invention relates to an artificial heart valve, which comprises a valve stent, a first sealing membrane, a second sealing membrane, valve leaflets and valve leaflet anchoring members. The valve stent includes an inflow section and an outflow section; the first sealing membrane is attached to the outer side of the valve stent and comprises a hydrophilic swelling material, which can absorb liquid and swell after contacting with blood, for reducing paravalvular leakage; the second sealing membrane is arranged on the outer side of the first sealing membrane and at least covers all regions corresponding to the outer surface of the inflow section, for increasing the friction with the native valve leaflets; the valve leaflets are arranged inside the valve stent for controlling the unidirectional flow of blood; the valve leaflet anchoring members are spiral and can be coiled outside the mitral / tricuspid chordae tendineae plexus and interact with the valve stent. By providing the first sealing membrane and the second sealing membrane, the artificial heart valve of the present invention can better fit with the native tissue after being implanted into the mitral / tricuspid valve, so as to effectively prevent the occurrence of paravalvular leakage.

The invention relates to a simulator comprising a flexible simulation chamber simulating a living body chamber, the flexible simulation chamber having at least one opening; a valve comprising a valve leaflet; a papillary muscle entity model; and chordae tendineae connecting the papillary muscle entity model and the valve leaflets; at least one valve arm extends through the flexible simulation cavity, so that the far end of the valve arm is arranged in the flexible simulation cavity, the near end of the valve arm is arranged outside the flexible simulation cavity, the far end of the valve arm is fixed relative to the papillary muscle entity model, and the position of the far end of the valve arm can be controlled from the near end; and a control device for controlling the simulation process. Such a simulator allows for precise simulation of motion of a living body chamber, such as the left ventricle or the right ventricle of a human heart, in which case precise rotation and / or other motion of the chamber during a pulsation can be simulated.

The present invention discloses a self-expanding atrioventricular valve prosthesis device, comprising: a main body portion, which is a frame structure, and the main body portion is implanted at the native valve annulus of the heart. The main body portion includes an inflow section, an outflow section and a transition section. The inflow section is located at the atrial end, the outflow section is located at the ventricular end, and the transition section is located between the inflow section and the outflow section; it further includes at least one artificial valve leaf, which is fixed to the transition section of the main body portion, and the artificial valve leaf is provided with a connecting portion; it further includes a chordae tendineae portion, one end of which is fixed, and the other end is connected to the artificial valve leaf through the connecting portion. The present invention restricts the movement range of the artificial valve leaf through the chordae tendineae portion, and the connecting portion prevents the chordae tendineae portion from tearing and stress concentration on the valve leaf, thereby increasing the durability of the artificial valve leaf.

This application provides a transcatheter artificial chordae tendineae implantation device and system with easy clamping capability. The transcatheter artificial chordae tendineae implantation device includes a clamp assembly, a drive assembly, a puncture assembly, and a delivery assembly. The clamp assembly includes a first clamp and a second clamp, which are arranged side-by-side along the axial direction of the clamp assembly, with the proximal end of the first clamp movably connected to the proximal end of the second clamp. The drive assembly is connected to the first clamp and / or the second clamp and drives the distal end of the first clamp towards or away from the distal end of the second clamp to clamp the leaflet located between the first and second clamps. The puncture assembly extends from the clamp assembly to puncture the leaflet and implant the artificial chordae tendineae. The delivery assembly delivers the clamp assembly and the puncture assembly. In this application, the first and second clamps achieve relative opening and closing through axial rotation, and the clamping surface of the clamp assembly extends along the axial direction of the clamp assembly, giving the clamp assembly a large clamping area for easy clamping of the leaflet.

The present invention discloses a device for repairing tricuspid regurgitation by accordion chordae tendineae, comprising: a chord-gathering member for wrapping around and accordion-gathering the chordae tendineae; a fixing member connected to the chord-gathering member for positioning the device for repairing tricuspid regurgitation by accordion chordae tendineae; and a counterweight block at the connection between the chord-gathering member and the fixing member for stabilizing the chord-gathering member. The present invention effectively prevents the device for repairing tricuspid regurgitation by accordion chordae tendineae from moving upward by adding a counterweight block between the accordion-gathering hollow rod of the chord-gathering member and the fixing member. The position of the counterweight block can be adjusted to adjust the center of gravity of the device for repairing tricuspid regurgitation by accordion chordae tendineae, further stabilizing the device and improving its fit with the heart, such as the atrial wall. Furthermore, the counterweight block is connected to the accordion-gathering hollow rod and the fixing hollow rod via threads, allowing the position of the counterweight block to be adjusted in advance according to the patient's heart shape.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient An anchor for engaging a papillary muscle or heart wall is described, wherein the anchor is movable between a delivery configuration and a deployed configuration. When the anchor is in the delivery configuration the anchor has a first outer dimension and when the anchor is in the deployed configuration the anchor has a second outer dimension. The first outer dimension is smaller than the second outer dimension. The anchor is engageable with a papillary muscle or a heart wall when the anchor is in the deployed configuration. The anchor comprises a plurality of arms coupled at a proximal end thereof to a body portion, at least one arm of the plurality of arms movable between a first position and a second position when the anchor moves from the delivery configuration to the deployed configuration. The plurality of arms each have a distal tip for engaging the papillary muscle or heart wall, wherein as the anchor is moved from the delivery configuration to the deployed configuration, the plurality of arms are movable from an elongated shape to a curved shape.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

The present invention provides an artificial chordae tendineae length adjustment system, comprising an implant and a wire embedding device. The wire embedding device includes: a hollow bending adjustment device, a wire feeder and a wire gripper that are arranged in parallel and movably penetrate through the bending adjustment device; the distal end of the wire feeder extends out of the distal end of the bending adjustment device and surrounds the artificial chordae tendineae, and the wire gripper extends out of the distal end of the bending adjustment device and picks up the distal end of the wire feeder to surround the artificial chordae tendineae; the wire gripper is received into the inner cavity of the bending adjustment device and drives the distal end of the wire feeder to fold, and the folded wire feeder pulls the artificial chordae tendineae, and the implant is conveyed along the folded wire feeder and houses the part of the artificial chordae tendineae pulled by the wire feeder. The artificial chordae tendineae length adjustment system provided by the present invention can adjust the length of the artificial chordae tendineae implanted in a patient, weaken or eliminate the long-term problems caused by the relaxation of the artificial chordae tendineae. At the same time, the adjustment method of the artificial chordae tendineae length adjustment system causes little damage to the artificial chordae tendineae, improves the service life of the artificial chordae tendineae, and reduces the surgical risk.

The utility model provides an auxiliary clamping simulation device for treating mitral valve regurgitation. The auxiliary clamping simulation device comprises a water bath, a rotating device arranged on the outer side of the water bath and a cam mechanism connected with the rotating device. The bottom support is fixed in the water bath, the valve ring structure is arranged on the bottom support, and the valve leaflet is connected with the valve ring structure and is connected with the cam mechanism through chordae tendineae. The valve leaflet is of a trumpet-like shell structure, one end of the valve leaflet is flat and provided with a first long-strip-shaped opening, the other end of the valve leaflet is cylindrical and provided with a second round opening, and the first opening and the second opening are communicated with each other. According to the auxiliary clamping simulation device for treating mitral valve regurgitation, training simulation operation can be carried out on the mitral valve repairing process, and experiment / clinical operation risks can be reduced.

This invention provides a cardiac anchor and a corresponding cardiac anchoring system. The cardiac anchor includes a locking assembly and an anchoring member extending distally from the locking assembly. The anchoring member has a connecting end for engagement with cardiac tissue. The locking assembly includes a base and a suture clamping member, the suture clamping member being movably connected to the proximal end of the base. The distal end of the base has a bearing portion, and the suture clamping member has a suture clamping portion. A suture is disposed between the bearing portion and the suture clamping portion. The suture clamping member moves relative to the base to drive the suture clamping portion to move the suture toward the bearing portion and clamp the suture to the bearing portion. This cardiac anchor and cardiac anchoring system not only ensure endothelial overgrafting after the cardiac anchor is anchored to cardiac tissue, but also further avoids damage to the native chordae tendineae, ultimately greatly ensuring and maintaining the therapeutic effect of the surgery.

The present invention discloses an artificial chordae tendineae regulation device and an artificial chordae tendineae regulation system. The artificial chordae tendineae regulation device includes a regulation main body member and a hook-shaped member. The regulation main body member is an elastic self-expanding member with a hollow interior, an open distal end, and a radial dimension at the distal end greater than that at the proximal end. The hook-shaped member includes at least one hook-shaped structure for hooking the artificial chordae tendineae. When the hook-shaped member hooks the artificial chordae tendineae, the hook-shaped structure of the hook-shaped member extends out of the distal end of the regulation main body member. After the hook-shaped member hooks the artificial chordae tendineae, the hook-shaped member is received in the regulation main body member and fixedly connected to the regulation main body member, and the hook-shaped member pulls a part of the artificial chordae tendineae into the regulation main body member, and the distal end of the regulation main body member abuts against the parts of the artificial chordae tendineae on both sides of the hook-shaped member. The artificial chordae tendineae regulation device and the artificial chordae tendineae regulation system of the present invention can perform real-time adaptive adjustment on the effective length of the artificial chordae tendineae.

Implantable devices formed of materials which are not readily imageable, and which may shift from a delivery configuration to a deployment configuration upon deployment, are delivered and deployed with a deployment / delivery device having sensors generating a signal indicating contact of the delivery / deployment device with tissue to guarantee purchase of the implantable device with tissue upon deployment. The implantable device may be a tissue anchor with talons which shift from a delivery configuration to a deployed configuration. The sensors may be positioned along a distal end of the delivery / deployment device to indicate purchase of the device with tissue, to ensure purchase of the talons with tissue upon deployment. The sensors may include at least three sensors, which may be spaced apart from one another, to indicate full contact of the distal end of the delivery / deployment device with tissue. The sensors may optionally be aligned with the talons.

Apparatus for use with an annuloplasty ring (20), and an atrioventricular valve of a heart of a mammalian subject. A plurality of chord-manipulation arms (26) each include a flexible material and a stiffening element (70), the stiffening elements being configured to provide desired shapes to the chord-manipulation arms (26), when the chord-manipulation arms are disposed in non-radially constrained configurations. The chord-manipulation arms (26) are configured to be deployed among chords of the atrioventricular valve, and subsequently, to cause a size of the valve annulus to decrease, by the chord-manipulation arms (26) being rotated such as to twist the native atrioventricular valve and pull the native atrioventricular valve radially inwards. The stiffening elements (70) are configured to be removed from the flexible material of the chord-manipulation arms and / or de-stiffened, such as to facilitate removal of the chord-manipulation arms (26) from among the chords. Other applications are also described.

A catheter for changing or manipulating a shape of a surrounding anatomical structure or position the catheter in relation to said surrounding anatomical structure has distal and proximal ends. Further the catheter includes at least a first body extending along the catheter in the distal end portion of the catheter, wherein said body has an activated state and inactivated state. In said activated state a second diameter or a second volume of the body is bigger than a first diameter or a first volume of the body in said inactivated state. In addition, in said activated state said body is configured to support the catheter to an anatomical structure surrounded the catheter, such as e.g. chordae, blood vessel or urethra, and thereby change a relative position of the catheter and the surrounding anatomical structure and again to change or manipulate the shape of the surrounding anatomical structure or position the catheter in relation to said surrounding anatomical structure.

Systems and methods of atrioventricular valve replacement are provided. In various embodiments, an arch-like support structure is provided that is insertable and implantable into a heart and is positioned in the mitral annulus to replace a native mitral valve. The support structure is operable to support, and various systems comprise leaflet and chord structures operable to control and regular blood flow between chambers of the heart.

Disclosed are systems and methods of removing heart valve therapy. The systems and methods may include chordae cutting devices having unique shape memory curvature, capture basket catheters with mesh baskets, and leaflet cutting tools with unique shapes that may be pulled through leaflet tissue.

Devices, systems, and method for adjusting and setting tension of an artificial chordae tendineae. The artificial chordae tendineae is coupleable between a leaflet clip and a tissue anchor. A locking assembly, through which the artificial chordae tendineae extends, is shiftable between a tension-adjusting configuration, in which the artificial chordae tendineae is movable to adjust tension on the leaflet, and a tension-setting or locked configuration, in which the artificial chordae tendineae is inhibited or prevented or locked against moving with respect to the locking assembly to set or fix tension on the leaflet.

The invention relates to a laterally deliverable transcatheter prosthetic valve and a method for delivering and anchoring the same. A laterally deliverable prosthetic valve includes an outer frame, a flow control component mounted within the outer frame, and an anchoring element coupled to a distal side of the outer frame. The prosthetic valve is collapsible along the longitudinal axis and compressible along the central axis into a compressed configuration for lateral delivery through the delivery catheter, and is expandable to an expanded configuration when released from the delivery catheter. An end of the anchoring element is configured to engage a guidewire. The anchoring element extends during deployment to allow the anchoring element to capture at least one of the autologous leaflets or chordae and, in response to detachment of the guidewire from the end, transitions to a folded configuration to secure the at least one of the autologous leaflets or chordae between the anchoring element and the distal side of the outer frame.

A surgical instrument 1 for a valve repair surgery in an animal enables determination of the length of an artificial suture even when the tendinous cord length of a normal tendinous cord is not used as a reference. The surgical instrument 1 for a valve repair surgery in an animal comprises: a support part 20 which is rod-shaped and in which one-side end thereof in the longitudinal direction can abut a ventricle 56 of a heart 50 in an animal; and a suture holding part 30 which is provided at the other-side end of the support part 20, has three projections 32A, 32B, 32C on an end surface, and can abut a valve cusp 52 of the heart 50.

The utility model discloses a mitral valve measuring device which comprises a chordae tendineae length measuring rod, a chordae tendineae length identification frame, a valve leaflet height measuring rod, a valve leaflet height identification handle, an elastic clamping strip and a fixing nail column. A leaflet height measuring rod is hinged to one end, away from the chordae tendineae length measuring rod, of the chordae tendineae length marking frame, the swing angle of the leaflet height measuring rod is 90 degrees, and the chordae tendineae length measuring rod, the first handle, the first scale marks and the chordae tendineae length marking frame are arranged, so that the first handle is held to measure the chordae tendineae length. The chordae tendineae length measuring rod can extend into the left ventricle through the mitral valve opening, the width of the chordae tendineae length identification frame is gradually reduced from one end close to the valve leaflet height measuring rod to the other end, the chordae tendineae length identification frame can better fit the mitral valve leaflet, and it is guaranteed that the valve leaflet is measured in a natural state when extending. Through the chordae tendineae length identification frame, naked eyes can be assisted in observing readings on the first scale marks, and errors are reduced.

Guide wire apparatuses and methods. Guide wires may be utilized for guiding a delivery apparatus, for example a transcatheter mitral valve delivery apparatus to replace a native mitral valve. A guide wire may include a distal portion. The distal portion may define a central axis and comprise a distal tip. The distal portion may have an undeployed configuration in which the distal tip is contracted medially and centered on the central axis. The distal portion may have a deployed configuration in which the distal tip is expanded radially from the central axis such that, in multiple radial dimensions, the tip is thicker than a size of an opening between adjacent chordae tendineae of the mitral valve. The delivery apparatus may be configured to be passed along the wire to the mitral valve while the distal tip, in the deployed configuration, contacts the adjacent chordae tendineae without passing through the opening.

The present disclosure relates generally to the field of medical devices for delivering artificial chordae tendineae in a patient. A system for adjusting tension in an artificial chordae tendineae comprises a clip engageable with a leaflet of a heart valve. The system further comprises an anchor engageable with a papillary muscle or heart wall and an artificial chordae tendineae movable in a first direction and a second direction and coupleable between the clip and the anchor. The anchor includes a body portion and a locking portion comprising a housing portion configured to receive therein a portion of the artificial chordae tendineae. The locking portion is engageable with the artificial chordae tendineae and moveable between an unlocked configuration and a locked configuration, wherein in the unlocked configuration the locking portion is configured to allow movement of the artificial chordae tendineae and wherein in the locked configuration the locking portion is configured to prevent movement of the artificial chordae tendineae, An actuator is coupleable to the locking portion, where the actuator is configured to move the locking portion between the unlocked and locked configuration.

The application provides a heart valve positioning device which is detachably connected with a delivery system, the heart valve comprises a native valve ring and a native valve leaflet, and the heart valve positioning device comprises: a cylindrical support provided with at least one connecting piece; a plurality of first clamping pieces which are distributed along the outer periphery of the support and are connected with the support; a second clamping piece which is configured to be sleeved on the outer periphery of the first clamping piece; in a delivery state, the heart valve positioning device is contracted in the delivery system, and the connecting piece is connected with the delivery system; in a release state, the connecting piece is separated from the delivery system, the native valve leaflet is clamped between the first clamping piece and the support, and the second clamping piece is folded from the outer periphery of the first clamping piece and clamps the native valve leaflet, so that the native valve leaflet forms a folded structure. The heart valve positioning device of the application can easily pass through chordae tendineae to hook and support the native valve leaflet, and is simple, easy and fast to operate.

This invention provides a valve repair device, a valve repair system, and its operating method. The lifting components are all rigid structures, with the proximal end of each lifting component rotatably connected to the distal end of a stop structure. The distal end of each lifting component is rotatably connected to the distal end of a drive rod, allowing the shape of the lifting components to change through axial movement of the drive rod. This enables the lifting components to lift, clamp, and release chordae tendineae within a 0°–360° range, reducing the number of product specifications and significantly increasing the flexibility and convenience of the surgeon's operation. Furthermore, during surgery, if the valve repair device gets caught on the chordae tendineae, the flexible structure allows for a larger angle and smaller diameter in the open state, making release easier.