88 results about "Heart apex" patented technology

The invention relates to the technical field of medical image analysis, in particular to a left ventricular compliance assessment method and system based on medical image.The method comprises the following steps that a planar three-dimensional coordinate from a left ventricular apex to a mitral annulus is obtained through a CT image, a thin-plate spline interpolation algorithm is called to establish a left ventricular long-axis model, the ultrasonic end-stage internal diameter is obtained synchronously, and a left ventricular compliance assessment result is obtained. And inputting the left greenhouse long axis model and the ultrasonic diastole end-stage inner diameter into an Euclidean distance calculation function to generate a left greenhouse length-diameter ratio. According to the method, a left greenhouse long axis model is constructed by integrating CT three-dimensional coordinates and ultrasonic inner diameter, the length-diameter ratio is calculated by combining Euclidean distance, point cloud registration is carried out, a myocardial wall area is segmented, local deformation is quantized by utilizing Gaussian curvature gradient, a correction factor is generated by inputting a radial basis function network, and a parameter coupling mechanism is established by fusing an aorta root angle. And optimizing the weight of the pressure-volume equation, establishing a dynamic model, and realizing a quantitative evaluation system of spatial heterogeneity and time continuity.

The invention provides a left heart data analysis method and system based on image segmentation, and relates to the technical field of medical image processing. Comprising the following steps: acquiring cardiac ultrasound image data and preprocessing; performing image segmentation on the preprocessed image data to obtain a segmentation result including a left ventricle, a left ventricular wall and a left atrium; searching a boundary line of the left ventricle and the left atrium, selecting two boundary points corresponding to the minimum and maximum abscissas in the boundary line as left and right mitral valve ring points respectively, and establishing a long axis based on the mitral valve ring midpoint and the cardiac apex point; modeling the ventricle into a structure formed by superposing a plurality of discs along the long axis direction, and obtaining the diameter of the corresponding disc; based on the obtained diameters of the corresponding discs, the left ventricular volumes in the diastolic period and the systolic period are calculated respectively, and the left ventricular ejection fraction is calculated. According to the method, image segmentation and geometric modeling are fused to achieve accurate calculation of the cardiac ejection fraction, meanwhile, the accuracy of cardiac structure image segmentation is improved, and an interpretable ejection fraction estimation process is achieved.

Methods and systems are provided for identifying cardiac cycles for evaluating left ventricle function using only image data. In one example, a method includes obtaining a sequence of medical image frames of a heart of a patient over a plurality of cardiac cycles, wherein each medical image frame depicts the same apical view of the heart, using a timing model to generate an output that is useable to label each frame of the sequence by cardiac cycle subphase and using the output to determine the suitability of each cardiac cycle for performing an automated measurement. The method may further include using the suitability of each cycle to determine if an automated measurement should be performed on each cycle, where automated measurements are performed on medical image frames corresponding to suitable cycles and automated measurements are not performed on medical image frames corresponding to unsuitable cycles.

Various embodiments include methods for generating patient-specific heart and thorax models using anatomical landmarks and segmentation data, optimized through the application of trained neural network models. Three-dimensional medical imaging data may be processed by a trained neural network to automatically segment and isolate the heart, blood cavities, and thorax to extract feature maps from the segmented images. Anatomical landmarks, such as the heart apex and valve centers, are identified and the alignment of heart axes is verified. Reference heart and thorax models are selected and adapted to fit the patient-specific landmarks through scaling, translating, and rotating. Best adapted heart and thorax models may then be used for conducting one or more medical procedures. Neural network models, trained on historical patient data sets, may be refined through machine learning from new patient data, thereby improving accuracy.

The invention discloses application of a JMJD6-targeted reagent in preparation of a medicine for promoting myocardial cell proliferation. The medicine can promote myocardial cell proliferation after myocardial infarction and reduce the myocardial fibrosis scar area caused by myocardial infarction. AAV9 myocardial specific overexpression virus and JMJD6 myocardial specific knockout mice are utilized, and the positive effect of JMJD6 in promotion of P1 cardiac apex resection of newborn mice and regeneration and repair of injured hearts after myocardial infarction of adult mice is disclosed for the first time; the specific mechanism is that JMJD6 depends on the activity of histone demethylase, enrichment of active modification H4R3me2a and H3R2me2s in a PDK4 promoter region is removed, transcriptional expression of the H4R3me2a and the H3R2me2s is inhibited, an impaired heart energy substrate utilization mode is stimulated to be increased and converted from fatty acid oxidation energy supply to glycolysis oxidation energy supply, and then adult myocardial cell proliferation is effectively promoted. The regeneration and repair capability of the heart after myocardial infarction is greatly improved, and a new effective target spot is provided for clinical treatment of myocardial injury.

The utility model relates to the technical field of medical instruments, in particular to a pacemaker electrode wire, which comprises a wire conduit, the wire conduit comprises a head part and a tail part which are connected with each other, the head part is provided with an electrode assembly, and the electrode assembly comprises a first electrode and a second electrode which are electrically connected with each other. The first electrode and the second electrode are arranged in a spaced mode in the direction from the head to the tail, and a fixing piece located between the first electrode and the second electrode is arranged on the outer side of the wire conduit. The head of the wire conduit can be sent to the right ventricular apex of the heart of a patient through vein puncture, and the fixing piece is in contact with and fixed to the surface of the endocardium, so that the first electrode is firmly fixed to the right ventricular apex, the electrode wire is kept stable in the heart of the patient, and the electrode wire is prevented from shifting or falling off; and the normal cardiac function of the patient is ensured.

A biostimulator and a biostimulator system for septal pacing, is described. The biostimulator includes an articulation to allow an electrode axis of a pacing electrode to be directed differently than a housing axis of a housing. The housing contains electrical circuitry that is electrically connected to the pacing electrode. The differently directed axes allow the pacing electrode to affix to target tissue of an interventricular septal wall of a heart when the housing of the biostimulator is located near an apex of the heart. The articulation can include a flexible portion of an extension, a hinge, or a tether. Other embodiments are also described and claimed.

The utility model discloses a fixing strap for a temporary pacemaker, which comprises a shoulder strap and a binding strap, an extension bag is sewed below the shoulder strap, a zipper is sewed on the surface of the extension bag, a weight is stored in the extension bag, and a binding surface is arranged at the bottom end of the extension bag; a traction piece is arranged on the surface of the extension bag and used for changing the position of the extension bag, and the fixing band is used in cooperation with the fixing band at the position, close to the apex of the right ventricle, of the extension bag after being worn, so that the fixing band can keep a good attaching effect whether daily activities or mild exercises are carried out; and the risk of complications caused by displacement of the pacemaker or poor contact of the electrodes is reduced. The bonding head is bonded to the bonding female end area by pulling the traction belt, it can be ensured that the position of the extension bag after adjustment is kept stable, that is, the position of the extension bag is changed through traction of the traction belt, and the position of the extension bag is accurately adjusted.

The application relates to the field of medical devices, in particular to an implant capable of avoiding interlayer reflux, which comprises an anchoring device, a closing aid, and an adjusting mechanism, the closing aid is fixed on atrial tissue through the anchoring device, one end of the adjusting mechanism is connected with the closing aid, and the other end of the adjusting mechanism is fixed on ventricular tissue or apical tissue, the closing aid comprises a first patch and a second patch, one side of the first patch close to the anchoring device is a root, and the other side of the first patch away from the anchoring device is a head, wherein the first patch is arranged above the second patch, and the first patch and the second patch cooperate to form a pocket structure with an opening direction towards the head direction; the application can effectively avoid the existence of a gap between the closing aid and the autologous valve leaflet, so that blood flowing into the gap can be prevented from being accumulated into thrombus, calcified and other adverse conditions, and the application has good clinical significance.

A volume management apparatus includes a cardiac evaluation unit configured to evaluate whether the patient suffers from an organic heart disease based on an image of apical four chamber view; a parameter determination unit configured to determine a maximum inner diameter of inferior vena cava and a collapse rate of inferior vena cava based on an image of subxiphoid inferior vena cava view; a score calculation unit configured to determine scores that correspond to the LVEF value, the maximum diameter of the inferior vena cava, and the collapse rate of the inferior vena cava, respectively; and a fluid management plan determination unit configured to search for a fluid management plan corresponding to a score determined, and to perform volume management for the patient according to the fluid management plan searched.

The invention provides a coronary heart disease echocardiogram pathological feature extraction method and system. Static structure features and myocardial function features of the heart of a target coronary heart disease patient are determined through an ultrasonic video stream of the heart of the target coronary heart disease patient; determining a region mapping matrix of a relationship between a coronary artery blood supply region of the target coronary heart disease patient and a myocardial injury state according to the static structural characteristics and the myocardial functional characteristics, and determining boundary sharpening development of a pathological region in the heart of the target coronary heart disease patient according to the region mapping matrix; acquiring a myocardial movement track of the target coronary heart disease patient, and determining a longitudinal strain gradient of a basal segment and a cardiac apex segment of the heart of the target coronary heart disease patient according to the myocardial movement track; and based on the boundary sharpening development and the longitudinal strain gradient of the pathological area and in combination with the clinical pathological data of the target coronary heart disease patient, generating the cardiac physical characteristics of the target coronary heart disease patient. According to the scheme, the static structure and the dynamic function of the heart can be effectively associated and fused to extract the coronary heart disease echocardiogram features.

This invention relates to the field of image segmentation technology, and in particular to a method, apparatus, device, and storage medium for segmenting three-dimensional heart images. The method includes: extracting the intermediate layer region of interest (ROI) of the three-dimensional heart image to be segmented using a preset intermediate layer segmentation model; spreading the intermediate layer ROI to the basal and apical layers of the three-dimensional heart image to be segmented to obtain an overall ROI image; and segmenting the overall ROI image using a preset overall segmentation model to obtain a segmentation result for the three-dimensional heart image to be segmented. Because this invention first segments the intermediate layer image of the three-dimensional heart image to be segmented, then spreads the segmentation result to the entire three-dimensional heart image to be segmented, and finally segments the entire three-dimensional heart image to obtain a segmentation result, compared with existing methods, this invention can reduce the image data involved in segmentation and improve the accuracy of the segmentation result.

This invention discloses an adjustable ventricular connection device for mounting a blood pump at the apex of the heart. It includes an apical suture assembly for suturing to the apex of the heart and a blood pump connection assembly. The apical suture assembly includes a suture ring and an elastic outer suture ring. The outer suture ring is fixedly connected to the suture ring and both are fitted onto the inlet tube of the blood pump, with the inner ring of the outer suture ring sealingly fitting against the outer wall of the inlet tube. The blood pump connection assembly includes an adjusting and fixing ring and a fastener. The adjusting and fixing ring is fitted onto the inlet tube and fixedly connected to the suture ring. The fastener secures the adjusting and fixing ring to the inlet tube, and its position on the inlet tube can be adjusted by loosening the fastener. This invention allows adjustment of the position of the apical suture assembly and the blood pump connection assembly on the inlet tube, enabling adjustment of the optimal insertion depth of the inlet tube into the ventricle according to the myocardial thickness of different patients, achieving individualized treatment to meet the needs of patients with different myocardial thicknesses.

Provided is a health monitoring device that extracts, in particular, an apical beat component from a trunk acoustic pulse wave and thus is also usable in the medical field. The health monitoring device (1000) of the present invention analyzes a trunk acoustic pulse wave to estimate the health condition of a person using a correlation of an indicator relating to a left ventricular pressure waveform which indicates the behavior of the heart, with a vibration frequency of a frequency component stemming from an apical beat, a diastolic time interval in a cardiac cycle, or blood pressure. The former is input information and the latter is output information of the heart through which blood circulates, and thus comparing these two pieces of information makes it possible to know a health condition relating to the function of the heart more accurately than conventionally.

A transapical removal device that can be deployed in a catheter procedure to capture for removal or alteration a mitral valve clip or heart tissue, such as the anterior leaflet of the mitral valve, and methods of use are disclosed. The removal device includes a delivery catheter configured to be deployed near a mitral valve using a guide catheter. The delivery catheter has a snare head at the distal end, which assumes a collapsed state during movement of the delivery catheter through the guide catheter and deployed state for capturing a mitral valve clip or anterior leaflet. The snare head has one or more ablation delivery catheters configured to ablate tissue surrounding the pre-positioned mitral valve clip or anterior leaflet. In some arrangements within the scope of the present disclosure, the removal device includes a deployment mechanism for deploying a new transcatheter valve into the mitral valve.

Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and / or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.

The utility model discloses a catheter sealing device for transcardiac apex first aid. The catheter sealing device comprises a telescopic disc made of a shape memory alloy material and a spiral push rod used for achieving state change of the telescopic disc. The telescopic disc is provided with anchoring claws and developing rings distributed in the circumferential direction. The telescopic disc has an unfolded state and a closed state, and the telescopic disc is pre-shaped into a shape in the closed state; in the unfolded state, the telescopic disc is in a hexagonal plum blossom shape, in the closed state, the telescopic disc is provided with an inwards-concave triangle and an outwards-protruding triangle, each corner is in threaded connection with a spiral push rod, and the inwards-concave triangles can be unfolded under the pulling action of the spiral push rods, so that the telescopic disc is converted into the unfolded state from the closed state. The device is simple in structure, easy and convenient to operate and capable of rapidly opening and closing a cardiac apex channel, sealing a catheter and reducing bleeding when being used for transapical cardiac apex first aid.

An implantable medical device delivery system includes a delivery catheter including an elongated body having a first portion defining a first lumen and a second portion defining a second lumen. An angle is defined between first and second axes defined by the first and second portions, respectively. The second axis is directed toward a left ventricular (LV) apex of a heart of a patient when the first axis is directed toward a CS. The first portion or elongated element can extend into the CS to anchor the delivery catheter relative to an orientation of the CS.

The invention discloses an echocardiography value measuring method based on multi-modal large model workflow, and belongs to the technical field of medical image processing. According to the method, the problems of low value measurement accuracy and low report generation efficiency in the traditional cardiac ultrasonic examination are solved. According to the technical scheme, the method comprises the steps of reading an echocardiogram video stream to obtain a to-be-recognized sequence; preprocessing the data; obtaining section type information through a section classification and quality control model, wherein the section type information comprises a cardiac apex four-cavity section, a cardiac apex two-cavity section and a sternum-side long-axis section; inputting the section type information and the past medical history of the patient into a large language model to generate a calling instruction; calling a corresponding visual parameter measurement model according to the instruction to complete heart structure parameter measurement; and summarizing measured value information, inputting the measured value information into the large language model, and automatically generating a structured cardiac ultrasound examination report in combination with measured value parameters and clinical information. According to the method, multi-model cooperative processing is realized through multi-modal information fusion and intelligent scheduling, and the cardiac ultrasound measurement value accuracy and the diagnostic report normalization are improved.

The application discloses a kind of blood pump fixed position adjustable ventricle connecting device, comprising: apex suture assembly and adjustable connecting assembly, apex suture assembly includes suture washer and snap ring, snap ring is equipped with first connecting ring, second connecting ring with opening and is integrally connected on the side of first connecting ring and connecting block;Adjustable connecting assembly includes clamp and fastener, clamp is equipped with hoop body with opening and two connecting lugs connected in hoop body both ends, hoop body is arranged in second connecting ring, and positioning pin is arranged on hoop body, and positioning pin is movably inserted in the positioning hole of second connecting ring;Two connecting lugs stretch out from the opening of second connecting ring, fastener is connected on connecting block with two connecting lugs, and when fastener rotates, the inner diameter of hoop body can be contracted or expanded.The application can adjust the fixed position of ventricle connecting device on inlet pipe according to patient needs, and control the best depth of inlet pipe inserted into ventricle.

A catheter apparatus includes a first catheter, a housing configured to contain a laceration device in the retracted configuration, and a distal attachment device. In aspects, the first catheter can be within the outer catheter, and the housing can be movably attached to the outer catheter and surround a portion of the first catheter. In aspects, the housing can be within the first catheter, and the laceration device can extend beyond the first catheter in a deployed configuration. Methods of ameliorating septal hypertrophy of a heart include positioning a distal end of a first catheter at a first location proximate an aortic valve and extending the first catheter towards an apex of a left ventricle. Methods include anchoring the distal end to a second location proximate the apex. Methods include activating a laceration device to lacerate a portion of the septal wall between the apex and the aortic valve.

The invention discloses an interventional valve ring device and an interventional valve device. The interventional valve ring device and the interventional valve device can be used for mitral valve and tricuspid valve lesions. The interventional valve ring device is mainly composed of a valve ring, a valve ring conveying system, a fixing nail and a fixing nail conveying system. The interventional valve is mainly composed of a fixing support, a supporting support, a supporting support covering film and valve leaflets. The interventional valve ring and the interventional valve enter the heart through the interventional delivery system and can pass through the apex of the heart, the femoral vein, the jugular vein or the subclavian vein, the right atrium or the left atrium. The interventional valve is fixed in the interventional valve ring, and a minimally invasive, safe and effective treatment method can be provided for a patient.

The invention provides a method for measuring the left ventricular ejection fraction of a dynamic echocardiography. The method comprises the following steps: inputting a to-be-identified echocardiogram sequence into a neural network segmentation model based on multi-frame feature aggregation, then performing spatial feature coding on each frame of image of the to-be-identified echocardiogram sequence through a spatial feature encoder structure to obtain a spatial feature map corresponding to each frame of image, and finally, identifying the to-be-identified echocardiogram sequence according to the spatial feature map. Performing cross-frame and cross-section spatio-temporal feature aggregation on the spatial feature pattern through a spatio-temporal feature aggregation structure to obtain global spatio-temporal features including time sequence information of a heart apex two-cavity section and a heart apex four-cavity section; the left ventricular ejection fraction determining method comprises the steps of generating a left ventricular membrane segmentation mask of a terminal diastole frame and a terminal systole frame on the basis of global spatial-temporal characteristics and spatial shallow layer characteristics corresponding to the terminal diastole frame and the terminal systole frame, and finally determining the left ventricular ejection fraction on the basis of the left ventricular membrane segmentation mask of the terminal diastole frame and the terminal systole frame.

The application relates to the field of medical devices, in particular to a heart implant, which comprises an anti-reflux prosthesis, a fixing member and a limiting member, the anti-reflux prosthesis is anchored on atrial tissue through the fixing member, one end of the limiting member is connected with the anti-reflux prosthesis, and the other end of the limiting member is fixed on apical tissue, the anti-reflux prosthesis comprises a closing aid and a barrier, the distal end of the barrier is fixed on the middle region of the closing aid, the proximal end of the barrier is connected with the limiting member, and the proximal end part of the closing aid is free; the application not only can increase the coaptation area with adjacent native leaflets to achieve ideal repair effect, but also can avoid the closing aid from floating into the atrium, and has good clinical significance.

An ultrasound diagnostic apparatus includes processing circuitry and a display. The processing circuitry is configured to concurrently obtain a plurality of cardiac function indexes for at least two or more cardiac chambers including a left ventricle and a right ventricle among cardiac chambers appearing on an apical 4-chamber moving image of a subject during one or more heartbeats, based on boundary positions of the cardiac chambers appearing on the apical 4-chamber moving image. The display displays at least one or more of the plurality of cardiac function indexes.

The present disclosure relates an apical connector and a method for implanting and removing a ventricular assist device. The apical connector includes a first connection assembly and a second connection assembly. The first connection assembly includes a first base, a first positioning portion, and an annular cuff. The second connection assembly includes a second base and a first stopping portion. When the second base is mounted to the first through hole, the first stopping portion is located at a second position, and the first positioning portion is blocked on an end surface of the first stopping portion facing a first direction.

Disclosed herein are embodiments relating to methods for performing a minimally invasive procedure comprising delivering a linear annuloplasty ring using a delivery system. In some embodiments, the annuloplasty ring can be delivered using a transseptal or transapical approach. In some embodiments, the delivery system can position the annuloplasty ring using a flexible stabilizing mechanism and / or activate one or more anchors to extend outwardly from the annuloplasty ring.

The application discloses a heart apex integrated ECG body temperature and respiration mechanical sensing and alarming device, which comprises a flexible and fitted base suitable for the physiological arc of the fifth rib heart apex and the middle line of the left clavicle, a heart apex mechanical heart rate pulsation sensing component integrated in the center of the base, a thoracic mechanical respiration fluctuation sensing component in the peripheral area and a body temperature detection module in the inner side, and a built-in data processing and wireless transmission module and a local sound and light alarm; the device is pasted on the heart apex, pure mechanical top pressure elastic sheets and telescopic sensing strips are adopted to synchronously collect the body surface heart rate, the respiration frequency and the body temperature, the data is directly transmitted to the nurse mobile nursing PDA in real time, the local sound and light alarm and the PDA end pop-up window vibration alarm are simultaneously triggered when the heart rate is zero or the respiration stops, 24-hour continuous monitoring and on-the-spot immediate response of the critical signal are realized.

The application discloses a method and device for detecting cardiac output, electronic equipment and storage medium. The method comprises the following steps: acquiring cardiac ultrasound data of a target scanning object, and determining the section type corresponding to each section image in the cardiac ultrasound data; acquiring a first section image with a section type of an apical three-chamber section or an apical five-chamber section from the cardiac ultrasound data, optimizing the frequency spectrum data corresponding to the first section image, and obtaining optimized frequency spectrum data; acquiring a second section image with a section type of a parasternal left ventricular long-axis section from the cardiac ultrasound data, and acquiring a left ventricular outflow tract diameter from the second section image; and calculating a target parameter according to the left ventricular outflow tract diameter and the optimized frequency spectrum data. The application can collect frequency spectrum data from a region of interest according to a sampling gate set by a region parameter of the region of interest, and automatically calculate the cardiac output according to the frequency spectrum data, so that the Doppler data collected by an ultrasonic probe is no longer needed, and the data analysis process is simplified.

The invention discloses a heart-shaped channel positive and negative wave coupling sound production and pickup device. A sound box relates to the technical field of acoustics, and is characterized in that a plurality of sound outlet holes are formed in the front surface of a box body shell along the edge of the box body shell; the loudspeaker unit is embedded in the box body shell and faces the front face of the box body shell, and the other face of the loudspeaker unit is located in the box body shell; the heart-shaped main cavity and the crescent-shaped auxiliary cavity are arranged in the box body shell, the heart-shaped main cavity is arranged on the peripheral side of the loudspeaker unit in a surrounding mode, and the crescent-shaped auxiliary cavity is located below the heart-shaped main cavity. According to the heart-shaped channel positive and negative wave coupling sound production and pickup device, a heart-shaped main cavity is firstly filled with backward waves generated by vibration of a vibrating diaphragm of a loudspeaker unit, and the backward waves enter a crescent-shaped auxiliary cavity through an opening in the apex part of the heart-shaped main cavity according to the physical function characteristics of the heart shape; and the air enters the air through a plurality of small holes distributed in the edge part of the crescent-shaped auxiliary cavity and is coupled with the forward wave of the loudspeaker unit.