66 results about "Heart apex" patented technology

The invention provides a left heart data analysis method and system based on image segmentation, and relates to the technical field of medical image processing. Comprising the following steps: acquiring cardiac ultrasound image data and preprocessing; performing image segmentation on the preprocessed image data to obtain a segmentation result including a left ventricle, a left ventricular wall and a left atrium; searching a boundary line of the left ventricle and the left atrium, selecting two boundary points corresponding to the minimum and maximum abscissas in the boundary line as left and right mitral valve ring points respectively, and establishing a long axis based on the mitral valve ring midpoint and the cardiac apex point; modeling the ventricle into a structure formed by superposing a plurality of discs along the long axis direction, and obtaining the diameter of the corresponding disc; based on the obtained diameters of the corresponding discs, the left ventricular volumes in the diastolic period and the systolic period are calculated respectively, and the left ventricular ejection fraction is calculated. According to the method, image segmentation and geometric modeling are fused to achieve accurate calculation of the cardiac ejection fraction, meanwhile, the accuracy of cardiac structure image segmentation is improved, and an interpretable ejection fraction estimation process is achieved.

Methods and systems are provided for identifying cardiac cycles for evaluating left ventricle function using only image data. In one example, a method includes obtaining a sequence of medical image frames of a heart of a patient over a plurality of cardiac cycles, wherein each medical image frame depicts the same apical view of the heart, using a timing model to generate an output that is useable to label each frame of the sequence by cardiac cycle subphase and using the output to determine the suitability of each cardiac cycle for performing an automated measurement. The method may further include using the suitability of each cycle to determine if an automated measurement should be performed on each cycle, where automated measurements are performed on medical image frames corresponding to suitable cycles and automated measurements are not performed on medical image frames corresponding to unsuitable cycles.

Various embodiments include methods for generating patient-specific heart and thorax models using anatomical landmarks and segmentation data, optimized through the application of trained neural network models. Three-dimensional medical imaging data may be processed by a trained neural network to automatically segment and isolate the heart, blood cavities, and thorax to extract feature maps from the segmented images. Anatomical landmarks, such as the heart apex and valve centers, are identified and the alignment of heart axes is verified. Reference heart and thorax models are selected and adapted to fit the patient-specific landmarks through scaling, translating, and rotating. Best adapted heart and thorax models may then be used for conducting one or more medical procedures. Neural network models, trained on historical patient data sets, may be refined through machine learning from new patient data, thereby improving accuracy.

The invention discloses application of a JMJD6-targeted reagent in preparation of a medicine for promoting myocardial cell proliferation. The medicine can promote myocardial cell proliferation after myocardial infarction and reduce the myocardial fibrosis scar area caused by myocardial infarction. AAV9 myocardial specific overexpression virus and JMJD6 myocardial specific knockout mice are utilized, and the positive effect of JMJD6 in promotion of P1 cardiac apex resection of newborn mice and regeneration and repair of injured hearts after myocardial infarction of adult mice is disclosed for the first time; the specific mechanism is that JMJD6 depends on the activity of histone demethylase, enrichment of active modification H4R3me2a and H3R2me2s in a PDK4 promoter region is removed, transcriptional expression of the H4R3me2a and the H3R2me2s is inhibited, an impaired heart energy substrate utilization mode is stimulated to be increased and converted from fatty acid oxidation energy supply to glycolysis oxidation energy supply, and then adult myocardial cell proliferation is effectively promoted. The regeneration and repair capability of the heart after myocardial infarction is greatly improved, and a new effective target spot is provided for clinical treatment of myocardial injury.

The utility model discloses a fixing strap for a temporary pacemaker, which comprises a shoulder strap and a binding strap, an extension bag is sewed below the shoulder strap, a zipper is sewed on the surface of the extension bag, a weight is stored in the extension bag, and a binding surface is arranged at the bottom end of the extension bag; a traction piece is arranged on the surface of the extension bag and used for changing the position of the extension bag, and the fixing band is used in cooperation with the fixing band at the position, close to the apex of the right ventricle, of the extension bag after being worn, so that the fixing band can keep a good attaching effect whether daily activities or mild exercises are carried out; and the risk of complications caused by displacement of the pacemaker or poor contact of the electrodes is reduced. The bonding head is bonded to the bonding female end area by pulling the traction belt, it can be ensured that the position of the extension bag after adjustment is kept stable, that is, the position of the extension bag is changed through traction of the traction belt, and the position of the extension bag is accurately adjusted.

The application relates to the field of medical devices, in particular to an implant capable of avoiding interlayer reflux, which comprises an anchoring device, a closing aid, and an adjusting mechanism, the closing aid is fixed on atrial tissue through the anchoring device, one end of the adjusting mechanism is connected with the closing aid, and the other end of the adjusting mechanism is fixed on ventricular tissue or apical tissue, the closing aid comprises a first patch and a second patch, one side of the first patch close to the anchoring device is a root, and the other side of the first patch away from the anchoring device is a head, wherein the first patch is arranged above the second patch, and the first patch and the second patch cooperate to form a pocket structure with an opening direction towards the head direction; the application can effectively avoid the existence of a gap between the closing aid and the autologous valve leaflet, so that blood flowing into the gap can be prevented from being accumulated into thrombus, calcified and other adverse conditions, and the application has good clinical significance.

A volume management apparatus includes a cardiac evaluation unit configured to evaluate whether the patient suffers from an organic heart disease based on an image of apical four chamber view; a parameter determination unit configured to determine a maximum inner diameter of inferior vena cava and a collapse rate of inferior vena cava based on an image of subxiphoid inferior vena cava view; a score calculation unit configured to determine scores that correspond to the LVEF value, the maximum diameter of the inferior vena cava, and the collapse rate of the inferior vena cava, respectively; and a fluid management plan determination unit configured to search for a fluid management plan corresponding to a score determined, and to perform volume management for the patient according to the fluid management plan searched.

The invention provides a coronary heart disease echocardiogram pathological feature extraction method and system. Static structure features and myocardial function features of the heart of a target coronary heart disease patient are determined through an ultrasonic video stream of the heart of the target coronary heart disease patient; determining a region mapping matrix of a relationship between a coronary artery blood supply region of the target coronary heart disease patient and a myocardial injury state according to the static structural characteristics and the myocardial functional characteristics, and determining boundary sharpening development of a pathological region in the heart of the target coronary heart disease patient according to the region mapping matrix; acquiring a myocardial movement track of the target coronary heart disease patient, and determining a longitudinal strain gradient of a basal segment and a cardiac apex segment of the heart of the target coronary heart disease patient according to the myocardial movement track; and based on the boundary sharpening development and the longitudinal strain gradient of the pathological area and in combination with the clinical pathological data of the target coronary heart disease patient, generating the cardiac physical characteristics of the target coronary heart disease patient. According to the scheme, the static structure and the dynamic function of the heart can be effectively associated and fused to extract the coronary heart disease echocardiogram features.

This invention discloses an adjustable ventricular connection device for mounting a blood pump at the apex of the heart. It includes an apical suture assembly for suturing to the apex of the heart and a blood pump connection assembly. The apical suture assembly includes a suture ring and an elastic outer suture ring. The outer suture ring is fixedly connected to the suture ring and both are fitted onto the inlet tube of the blood pump, with the inner ring of the outer suture ring sealingly fitting against the outer wall of the inlet tube. The blood pump connection assembly includes an adjusting and fixing ring and a fastener. The adjusting and fixing ring is fitted onto the inlet tube and fixedly connected to the suture ring. The fastener secures the adjusting and fixing ring to the inlet tube, and its position on the inlet tube can be adjusted by loosening the fastener. This invention allows adjustment of the position of the apical suture assembly and the blood pump connection assembly on the inlet tube, enabling adjustment of the optimal insertion depth of the inlet tube into the ventricle according to the myocardial thickness of different patients, achieving individualized treatment to meet the needs of patients with different myocardial thicknesses.

A transapical removal device that can be deployed in a catheter procedure to capture for removal or alteration a mitral valve clip or heart tissue, such as the anterior leaflet of the mitral valve, and methods of use are disclosed. The removal device includes a delivery catheter configured to be deployed near a mitral valve using a guide catheter. The delivery catheter has a snare head at the distal end, which assumes a collapsed state during movement of the delivery catheter through the guide catheter and deployed state for capturing a mitral valve clip or anterior leaflet. The snare head has one or more ablation delivery catheters configured to ablate tissue surrounding the pre-positioned mitral valve clip or anterior leaflet. In some arrangements within the scope of the present disclosure, the removal device includes a deployment mechanism for deploying a new transcatheter valve into the mitral valve.

Systems and methods are provided for repairing a heart valve, such as a mitral, tricuspid or aortic valve, using an adjustable and removable implant that can be delivered to the heart through the apex in a simplified and non-invasive manner. The implant can include a prosthetic valve portion coupled to a proximal end of a shaft, and an anchor portion coupled to a distal end of the shaft. The prosthetic valve can be suspended within an opening of the heart valve while the anchor portion is affixed to the apex of the heart. When the implant is deployed, a distance between the prosthetic valve portion and the anchor portion can be adjusted, and / or the implant or a portion thereof can be rotated to thereby change the position of the prosthetic valve within the heart valve. This can allow correcting for post-implantation movements of the implant to mitigate potential complications.

The utility model discloses a catheter sealing device for transcardiac apex first aid. The catheter sealing device comprises a telescopic disc made of a shape memory alloy material and a spiral push rod used for achieving state change of the telescopic disc. The telescopic disc is provided with anchoring claws and developing rings distributed in the circumferential direction. The telescopic disc has an unfolded state and a closed state, and the telescopic disc is pre-shaped into a shape in the closed state; in the unfolded state, the telescopic disc is in a hexagonal plum blossom shape, in the closed state, the telescopic disc is provided with an inwards-concave triangle and an outwards-protruding triangle, each corner is in threaded connection with a spiral push rod, and the inwards-concave triangles can be unfolded under the pulling action of the spiral push rods, so that the telescopic disc is converted into the unfolded state from the closed state. The device is simple in structure, easy and convenient to operate and capable of rapidly opening and closing a cardiac apex channel, sealing a catheter and reducing bleeding when being used for transapical cardiac apex first aid.

An implantable medical device delivery system includes a delivery catheter including an elongated body having a first portion defining a first lumen and a second portion defining a second lumen. An angle is defined between first and second axes defined by the first and second portions, respectively. The second axis is directed toward a left ventricular (LV) apex of a heart of a patient when the first axis is directed toward a CS. The first portion or elongated element can extend into the CS to anchor the delivery catheter relative to an orientation of the CS.

The invention discloses an echocardiography value measuring method based on multi-modal large model workflow, and belongs to the technical field of medical image processing. According to the method, the problems of low value measurement accuracy and low report generation efficiency in the traditional cardiac ultrasonic examination are solved. According to the technical scheme, the method comprises the steps of reading an echocardiogram video stream to obtain a to-be-recognized sequence; preprocessing the data; obtaining section type information through a section classification and quality control model, wherein the section type information comprises a cardiac apex four-cavity section, a cardiac apex two-cavity section and a sternum-side long-axis section; inputting the section type information and the past medical history of the patient into a large language model to generate a calling instruction; calling a corresponding visual parameter measurement model according to the instruction to complete heart structure parameter measurement; and summarizing measured value information, inputting the measured value information into the large language model, and automatically generating a structured cardiac ultrasound examination report in combination with measured value parameters and clinical information. According to the method, multi-model cooperative processing is realized through multi-modal information fusion and intelligent scheduling, and the cardiac ultrasound measurement value accuracy and the diagnostic report normalization are improved.

A catheter apparatus includes a first catheter, a housing configured to contain a laceration device in the retracted configuration, and a distal attachment device. In aspects, the first catheter can be within the outer catheter, and the housing can be movably attached to the outer catheter and surround a portion of the first catheter. In aspects, the housing can be within the first catheter, and the laceration device can extend beyond the first catheter in a deployed configuration. Methods of ameliorating septal hypertrophy of a heart include positioning a distal end of a first catheter at a first location proximate an aortic valve and extending the first catheter towards an apex of a left ventricle. Methods include anchoring the distal end to a second location proximate the apex. Methods include activating a laceration device to lacerate a portion of the septal wall between the apex and the aortic valve.

The invention discloses an interventional valve ring device and an interventional valve device. The interventional valve ring device and the interventional valve device can be used for mitral valve and tricuspid valve lesions. The interventional valve ring device is mainly composed of a valve ring, a valve ring conveying system, a fixing nail and a fixing nail conveying system. The interventional valve is mainly composed of a fixing support, a supporting support, a supporting support covering film and valve leaflets. The interventional valve ring and the interventional valve enter the heart through the interventional delivery system and can pass through the apex of the heart, the femoral vein, the jugular vein or the subclavian vein, the right atrium or the left atrium. The interventional valve is fixed in the interventional valve ring, and a minimally invasive, safe and effective treatment method can be provided for a patient.

The invention provides a method for measuring the left ventricular ejection fraction of a dynamic echocardiography. The method comprises the following steps: inputting a to-be-identified echocardiogram sequence into a neural network segmentation model based on multi-frame feature aggregation, then performing spatial feature coding on each frame of image of the to-be-identified echocardiogram sequence through a spatial feature encoder structure to obtain a spatial feature map corresponding to each frame of image, and finally, identifying the to-be-identified echocardiogram sequence according to the spatial feature map. Performing cross-frame and cross-section spatio-temporal feature aggregation on the spatial feature pattern through a spatio-temporal feature aggregation structure to obtain global spatio-temporal features including time sequence information of a heart apex two-cavity section and a heart apex four-cavity section; the left ventricular ejection fraction determining method comprises the steps of generating a left ventricular membrane segmentation mask of a terminal diastole frame and a terminal systole frame on the basis of global spatial-temporal characteristics and spatial shallow layer characteristics corresponding to the terminal diastole frame and the terminal systole frame, and finally determining the left ventricular ejection fraction on the basis of the left ventricular membrane segmentation mask of the terminal diastole frame and the terminal systole frame.

The application relates to the field of medical devices, in particular to a heart implant, which comprises an anti-reflux prosthesis, a fixing member and a limiting member, the anti-reflux prosthesis is anchored on atrial tissue through the fixing member, one end of the limiting member is connected with the anti-reflux prosthesis, and the other end of the limiting member is fixed on apical tissue, the anti-reflux prosthesis comprises a closing aid and a barrier, the distal end of the barrier is fixed on the middle region of the closing aid, the proximal end of the barrier is connected with the limiting member, and the proximal end part of the closing aid is free; the application not only can increase the coaptation area with adjacent native leaflets to achieve ideal repair effect, but also can avoid the closing aid from floating into the atrium, and has good clinical significance.

The present disclosure relates an apical connector and a method for implanting and removing a ventricular assist device. The apical connector includes a first connection assembly and a second connection assembly. The first connection assembly includes a first base, a first positioning portion, and an annular cuff. The second connection assembly includes a second base and a first stopping portion. When the second base is mounted to the first through hole, the first stopping portion is located at a second position, and the first positioning portion is blocked on an end surface of the first stopping portion facing a first direction.

The application discloses a heart apex integrated ECG body temperature and respiration mechanical sensing and alarming device, which comprises a flexible and fitted base suitable for the physiological arc of the fifth rib heart apex and the middle line of the left clavicle, a heart apex mechanical heart rate pulsation sensing component integrated in the center of the base, a thoracic mechanical respiration fluctuation sensing component in the peripheral area and a body temperature detection module in the inner side, and a built-in data processing and wireless transmission module and a local sound and light alarm; the device is pasted on the heart apex, pure mechanical top pressure elastic sheets and telescopic sensing strips are adopted to synchronously collect the body surface heart rate, the respiration frequency and the body temperature, the data is directly transmitted to the nurse mobile nursing PDA in real time, the local sound and light alarm and the PDA end pop-up window vibration alarm are simultaneously triggered when the heart rate is zero or the respiration stops, 24-hour continuous monitoring and on-the-spot immediate response of the critical signal are realized.

The application discloses a method and device for detecting cardiac output, electronic equipment and storage medium. The method comprises the following steps: acquiring cardiac ultrasound data of a target scanning object, and determining the section type corresponding to each section image in the cardiac ultrasound data; acquiring a first section image with a section type of an apical three-chamber section or an apical five-chamber section from the cardiac ultrasound data, optimizing the frequency spectrum data corresponding to the first section image, and obtaining optimized frequency spectrum data; acquiring a second section image with a section type of a parasternal left ventricular long-axis section from the cardiac ultrasound data, and acquiring a left ventricular outflow tract diameter from the second section image; and calculating a target parameter according to the left ventricular outflow tract diameter and the optimized frequency spectrum data. The application can collect frequency spectrum data from a region of interest according to a sampling gate set by a region parameter of the region of interest, and automatically calculate the cardiac output according to the frequency spectrum data, so that the Doppler data collected by an ultrasonic probe is no longer needed, and the data analysis process is simplified.

The invention discloses a heart-shaped channel positive and negative wave coupling sound production and pickup device. A sound box relates to the technical field of acoustics, and is characterized in that a plurality of sound outlet holes are formed in the front surface of a box body shell along the edge of the box body shell; the loudspeaker unit is embedded in the box body shell and faces the front face of the box body shell, and the other face of the loudspeaker unit is located in the box body shell; the heart-shaped main cavity and the crescent-shaped auxiliary cavity are arranged in the box body shell, the heart-shaped main cavity is arranged on the peripheral side of the loudspeaker unit in a surrounding mode, and the crescent-shaped auxiliary cavity is located below the heart-shaped main cavity. According to the heart-shaped channel positive and negative wave coupling sound production and pickup device, a heart-shaped main cavity is firstly filled with backward waves generated by vibration of a vibrating diaphragm of a loudspeaker unit, and the backward waves enter a crescent-shaped auxiliary cavity through an opening in the apex part of the heart-shaped main cavity according to the physical function characteristics of the heart shape; and the air enters the air through a plurality of small holes distributed in the edge part of the crescent-shaped auxiliary cavity and is coupled with the forward wave of the loudspeaker unit.

The present invention relates to a cardiac defibrillation lead comprising a lead body, an anode and a distal end which can be implanted in the upper septum of the heart, characterised in that said cardiac lead is configured to form a loop in the apical region of the heart.

This invention provides a tether adjuster and its method of use. The tether adjuster includes a housing, a clamping mechanism, and a tension adjusting mechanism. The clamping mechanism is connected to the distal end of the housing and is capable of clamping an apical pad. The apical pad is used to connect to the proximal end of the tether, and the distal end of the tether is connected to a heart valve prosthesis. The clamping mechanism includes a first driving part and a jaw. The jaw includes two clamping arms symmetrically arranged circumferentially on the housing. The first driving part is connected to the two clamping arms respectively and is used to drive the distal ends of the two clamping arms to move in a direction of mutual approach to open the jaw, or to drive the distal ends of the two clamping arms to move in a direction of mutual approach to close the jaw. The tension adjusting mechanism is connected to the housing and to the proximal end of the tether, and is used to drive the proximal end of the tether to move relative to the heart valve prosthesis to adjust the tension of the tether. When adjusting the tension of the tether using the tether adjuster, two symmetrically arranged clamping arms are used to clamp the apical pad, so that the apical pad is subjected to symmetrical and balanced clamping force, maintaining the stability of the apical pad. This allows the operator to manipulate the tension adjustment mechanism to move the proximal end of the tether and thus adjust the tension of the tether.

The present disclosure relates to α1A-AR agonist compounds, pharmaceutical compositions, and methods of using the compounds and composition for treating conditions associated with right ventricular failure. In addition the disclosed compounds and compositions can be used for treating cardiomyopathies, such as hypertrophic cardiomyopathy, dilated cardiomyopathy, arrhythmogenic cardiomyopathy, restrictive cardiomyopathy, left ventricular noncompaction, right ventricular failure (RVF), and takotsubo cardiomyopathy. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

The present application belongs to the field of medical devices, and particularly relates to a valve clamping device and a valve clamping system. The valve clamping device comprises a fixed base, at least one pair of clamping arms, the same number of clamping pieces as the clamping arms, and a driving assembly. The proximal end of the at least one pair of clamping arms is connected to the fixed base, and the at least one pair of clamping arms can be opened and closed relative to the fixed base. Each clamping piece is located between the fixed base and each clamping arm. The driving assembly comprises a driving shaft connected to the fixed base. The driving shaft moves along its own axial direction to drive the clamping arms to open and close relative to the fixed base. The proximal end of the driving shaft is used to detachably connect a delivery device. The valve clamping device can be used to deliver from the left ventricle to the vicinity of the mitral valve through the cardiac apex. The surgical entry is very close to the valve, the delivery path is short and straight, the delivery device does not need to be bent, is easy to adjust and control, takes less time, and is easier to operate, and has low requirements for the operation skills of the doctor.

Methods and systems are provided for identifying cardiac cycles for assessing left ventricular function using only image data. In one example, a method includes obtaining (402) a sequence of medical image frames of a heart of a patient over a plurality of cardiac cycles, where each medical image frame depicts a same cardiac apex view of the heart; using a timing model to generate (406) an output that can be used to mark each frame in the sequence by a cardiac cycle sub-phase; and using the output to determine (408, 504) the suitability of each cardiac cycle for performing the automatic measurement. The method may also include using the suitability for each cycle to determine whether an automatic measurement should be performed on each cycle, where the automatic measurement is performed (412) on a medical image frame corresponding to a suitable cycle and the automatic measurement is not performed on a medical image frame corresponding to an unsuitable cycle.

The invention relates to a mapping catheter. Comprising a first tube section, a plurality of electrode sets are arranged at the far end of the first tube section and comprise the first electrode set, the second electrode set and the third electrode set, the first electrode set is configured to map electric signals of the right ventricle apex part, the second electrode set is configured to map His beams, and the third electrode set is configured to map His beams; the third electrode group is used for detecting electric signals in the inferior vena cava of the heart; the first pipe section is an elastic pipe section, and one of a reamed hole or a boss is arranged at the near end of the first pipe section in the axial direction of the first pipe section; the far end of the second pipe section is provided with the other one of a reamed hole or a boss in the axial direction of the second pipe section, the boss is inserted into the reamed hole, and the first pipe section and the second pipe section are connected through welding; the second pipe section and the first pipe section are made of the same material, a supporting layer is arranged in the second pipe section, and the rigidity of the supporting layer is larger than that of the first pipe section. The mapping requirements of the mapping catheter on the His bundle and the right ventricle can be met, and the application range of the mapping catheter can be widened.

The present disclosure includes devices and techniques for threading one or more catheters to the apex or base of the right ventricle by transfemoral vein access to the right ventricle. The catheter can be passed through to turn upward, directed towards the mitral valve, by puncturing the ventricular septum into the left ventricle through the ventricular side or right side of the heart. From this entry point in the left ventricle, flail mitral valve leaflets can be sutured and tethered, pulled back into place, and re-attached with grounding anchors in the right ventricle, or embedded in the septal wall. The ventricular septal crossing technique may include passing a coaxial conduit through a first access conduit, where the first access conduit may act as a guide to direct an inner or second coaxial conduit toward a flail mitral valve leaflet.

This application discloses a cardiac image segmentation method and a cardiac image analysis method. The cardiac image segmentation method includes: acquiring the long-axis and short-axis data corresponding to the original cardiac magnetic resonance imaging (MRI) images; segmenting the long-axis and short-axis data respectively to obtain long-axis segmentation results and short-axis segmentation results; analyzing the long-axis and short-axis segmentation results based on a spatial registration method using covariance spectral decomposition to determine the short-axis apex and base positions, and removing redundant scan layers from the short-axis segmentation results to obtain short-axis data segmentation information containing only the heart. This method models the long-axis left ventricle segmentation results, achieves precise automatic localization of the apex and base of the heart through covariance spectral decomposition combined with spatial registration of projection extrema and short-axis slices, and then removes redundant scan layers from the short-axis segmentation results based on the short-axis apex and base positions to obtain accurate short-axis data segmentation information containing only the heart.