11 results about "Vascular access" patented technology

The invention belongs to the field of functional medical catheter preparation, and particularly relates to an antibacterial and anticoagulant dialysis catheter with a sodium alginate-graphene oxide coating and a preparation method of the antibacterial and anticoagulant dialysis catheter. The preparation method comprises the following steps: (1) mixing a graphene oxide dispersion liquid with a sodium alginate solution, then adding a water / alcohol mixed solvent, and then carrying out ultrasonic dispersion treatment to obtain a mixed solution; (2) performing plasma pretreatment on the polyurethane dialysis catheter to obtain a pretreated catheter; (3) immersing the pretreated conduit into the mixed solution, and after dip-coating is completed, sequentially standing and drying to obtain a primary gel layer conduit; and (4) immersing the primary gel layer catheter into a cross-linking solution, and then sequentially cleaning, gradient heating and curing. Efficient antibiosis and anticoagulation are achieved through the synergistic effect of materials, the coating is firm in combination and excellent in biocompatibility, the problems of thrombus formation, infection and the like of an existing dialysis catheter can be solved, and the coating is suitable for hemodialysis vascular access.

The present invention covers the use of chymase inhibitors in general and more in particular substituted bicyclically substituted uracils of general formula (I) as described and defined herein, and 3-methylbenzo-[b]thiophene)-2-sulfonamido derivatives of general formula (II) for manufacturing pharmaceutical compositions for the treatment or prophylaxis of stroke, pulmonary embolism, deep or superficial vein thrombosis, thrombotic microangiopathy, thrombotic microangiopathy in hypercoagulable states after infection, inflammation, transplantation, disseminated intravascular coagulation, vaccine-induced immune thrombotic thrombocytopenia, vascular access site thrombosis or occlusion.

The application provides an outpatient hemodialysis infection event monitoring system and a monitoring method, and is applied to the technical field of data processing. The application processes blood vessel access information of a target patient and outpatient hemodialysis cannulation records of the target patient, generates a hemodialysis event influence factor, processes dialysis physiological parameter information of the target patient within a preset time, generates hemodialysis monitoring parameter information of the target patient, processes historical infection data of the target hemodialysis patient, generates a hemodialysis prediction monitoring characteristic vector, processes the hemodialysis event influence factor, the hemodialysis monitoring parameter information of the target patient, the hemodialysis prediction monitoring characteristic vector and infection examination result information of the target patient based on a target hemodialysis event early warning model, and generates hemodialysis infection event early warning information.

The utility model relates to the technical field of internal fistula puncture, especially to a simple internal fistula puncture positioning card, which pulls out the positioning mechanism from the storage mechanism and sticks the positioning mechanism on the arm of a patient to realize positioning of the blood vessel access in the arm of the patient, and then stores the positioning mechanism in the storage mechanism after use, thereby improving the practicability of the simple internal fistula puncture positioning card, comprising a positioning mechanism, further comprising a storage mechanism, the positioning mechanism is installed on the storage mechanism, the positioning mechanism positions the puncture position, and the storage mechanism stores the positioning mechanism.

This application discloses an AI-based intelligent intravenous infusion access selection and complication prediction system. The system includes: a multimodal data acquisition module for collecting multi-source heterogeneous data of the target object; a digital twin modeling module for creating a vascular geometric model based on the multi-source heterogeneous data and a 3D reconstruction algorithm, and constructing a digital twin by combining dynamic physiological parameters; an AI engine for access decision-making and risk prediction, used to simulate and predict risk indicators of candidate access routes using the digital twin, the physicochemical properties of the drug to be infused, the characteristic parameters of candidate catheters, and three risk models; a dynamic risk simulation and decision data generation module for generating corresponding prediction curves based on the risk indicators of candidate access routes; and a data visualization module for visually displaying the quantitative risk comparison report and prediction curves. This system enables personalized vascular access risk simulation and precise, predictive access route decision-making.

The application aims to provide an intervention delivery system of a foldable blood pump capable of measuring arterial blood pressure and guiding precision and small trauma, comprising an extracorporeal sheath tube, an intracorporeal sheath tube and a dilator. A pressure sensor is arranged on the extracorporeal part of the intracorporeal sheath tube, and arterial blood is measured by measuring the pressure of the flushing liquid between the intracorporeal sheath tube and the catheter, thus solving a big problem of arranging the pressure sensor on the foldable blood pump; the pressure sensor located outside avoids forming a flow dead angle on the foldable blood pump, reduces thrombosis, and has low requirements for the selection of the sensor and low cost. The intracorporeal sheath tube extends into the left ventricle, the foldable blood pump is directly delivered into the left ventricle for release, and the cooperation of the intracorporeal sheath tube and the dilator ensures that the intracorporeal sheath tube does not enter other blood vessel passages during the intervention into the left ventricle from the blood vessel, thereby reducing the damage to the blood vessel and the valve; and the guide cone surface of the intracorporeal sheath tube improves the guiding precision and simplifies the operation steps.

Systems and method are configured for vascular and / or neurointerventional procedures. The systems and methods enable safe and rapid access, including percutaneous access, to the carotid artery and further to the cerebral or intracranial arteries for the introduction of interventional devices such as to treat disease conditions. The methods and devices can include a vascular access and retrograde flow system.

The application discloses a slow-release antibacterial medical dressing, and relates to the technical field of medical dressings, which comprises a liquid-permeation absorption buffer layer, the top of the liquid-permeation absorption buffer layer is fixedly connected with a slow-release antibacterial drug storage layer, and the top of the slow-release antibacterial drug storage layer is fixedly connected with a medical carrier area; the periphery of the medical carrier area is fixedly connected with low-sensitivity pressure adhesive fixed frames; the slow-release antibacterial medical dressing is provided with a composite structure of a porous carrier and antibacterial microcapsules through the slow-release antibacterial drug storage layer, and after the liquid-permeation absorption buffer layer absorbs wound exudates, the microcapsules are triggered to release at a uniform speed when wet, long-acting slow-release antibacterial effect of not less than 72 hours is realized, a postoperative and catheter high-risk infection window period is covered, one or more easy-to-tear catheter openings are preset on the medical carrier area, and the overall multilayer composite structure is used, so that general covering and fixing of blood dialysis catheters, central venous catheters and various vascular access and surgical incisions can be directly worn out without on-site cutting.

Biologic matrices designed to facilitate wound healing and related methods are disclosed. A matrix comprises a three-dimensional, resorbable collagen scaffold derived from a vascularized portion of a perfusion-decellularized mammalian organ or tissue. The scaffold features a porous structure with a plurality of interconnected pores originating from one or more outer surfaces, which are defined by intact vascular pathways of the perfusion decellularized mammalian organ or tissue. The porous configuration substantially enhances the scaffold's effective surface area, making it at least 5 times greater than that of a non-porous scaffold having equivalent outer dimensions. In certain embodiments, the surface area considering the interconnected pores can be 10 times larger, 15 times larger, or more than the non-porous scaffold of equivalent outer dimensions. The density of the scaffold can range from 2 milligrams per cubic centimeter to 20 milligrams per cubic centimeter, inclusive, further optimizing the matrix's performance for wound healing applications.