The invention discloses an air jet loom weaving method for a polyester cotton core-spun yarn fabric with a polyester filament as a core and cotton fiber wrapped outside polyester, which orderly comprises working procedures such as doubling, twist stabilization after twisting, warping and rebeaming, reeding, loom beam on-hook, adjustment of process parameters and so on. In the working procedure of batch warping, the rebeaming is performed on a sizing machine, and the sizing is not performed; during the reeding after the rebeaming, 50 to 100 percent of harness frame numbers are increased than the prior species according to the warp density; the weft-insertion time is adjusted to ensure that the weft-insertion time of previous group of auxiliary nozzles is longer than that of next group of the auxiliary nozzles and the weft-insertion time is orderly shortened in a step shape, and the entire auxiliary nozzles are synchronously closed at the same angle position. The working procedures after the adjustment effectively solve the problem that the dyeing of the polyester cotton core-spun yarn fabric has color difference after the polyester cotton core-spun yarn fabric is woven on an air jet loom, and ensure that the polyester cotton core-spun yarn fabric can be fully and normally woven on the air jet loom. The weaving efficiency can reach 96 percent, the rate of first-grade products when getting off the loom can reach more than 93 percent, woven cloth has qualified various indicators and fully satisfies the normal production of the dyeing and finishing, and no quality problem exists after the dyeing.