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High-compliance tissue engineering blood vessel preparation template and tissue engineering blood vessel

ActiveCN111714703AImprove complianceReduce the incidence of intimal hyperplasiaTissue regenerationBlood vesselsDecellularizationTunica intima
The invention belongs to the field of tissue engineering, and particularly relates to a high-compliance tissue engineering blood vessel preparation template. The high-compliance tissue engineering blood vessel preparation template comprises a framework main body (1) and an inner core (2), wherein the inner core (2) is arranged inside the framework main body (1); the outer diameter of the inner core (2) is matched with the inner diameter of the framework main body (1); the main body of the framework main body (1) comprises support layers (11) and degradation layers (12) in alternate arrangement; the inner surface and the outer surface of the framework main body are the support layers (11); and the degradation layers (12) are made of degradable materials. The high-compliance tissue engineering blood vessel preparation template is used for being implanted under the skin of an animal or being used for in-vitro tissue culture; then, the inner core (2) is pulled away; and after the decellularization treatment, the high-compliance tissue engineering blood vessel can be prepared. The high-compliance tissue engineering blood vessel preparation template has the beneficial effects that the tissue engineering blood vessel prepared by using the high-compliance tissue engineering blood vessel preparation template has good compliance; the intimal hyperplasia can be inhibited.
Owner:领博生物科技(杭州)有限公司
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