The invention discloses mould-proof anti-bacterial multi-fiber blended woven fabric. The mould-proof anti-bacterial multi-fiber blended woven fabric is formed by weaving warp yarns and weft yarns through an air jet loom and is characterized in that the warp yarns and the weft yarns comprise, by weight, 30-36 parts of isotatic polypropylene, 3-5 parts of cinnamyl aldehyde, 1-2 parts of thiocarbamide, 0.4-0.8 part of stannous mono-sulphate, 3-6 parts of kaolin, 25-34 parts of modal fibers, 20-25 parts of milk grass fibers, 19-26 parts of elastic cotton fibers, 23-28 parts of coconut carbon fibers, 7-9 parts of fluoro-siloxane resin, 8-12 parts of toluene diisocynate, 10-14 parts of butyl alcohol, 2-4 parts of root bark of white mulberry, 3-4 parts of skullcap, 80-90 parts of 1-butyi-3-methylimidazole acetate, 100-110 parts of 1-alyl-3-imidazolium chloride, 4-7 parts of assistant, and a proper amount of water. According to the manufacturing method of the mould-proof anti-bacterial multi-fiber blended woven fabric, the processes are simple, the method is easy to implement, and the functions of the manufactured woven fabric are comprehensive through reasonable selection of raw materials and scientific proportion design. According to the mould-proof anti-bacterial multi-fiber blended woven fabric, various plant fibers are added and are soaked through Chinese herbal medicine, in this way, the spinnability of plant fibers and the spinning quality are improved, all technical indexes of the woven fabric are increased, and the mould-proof anti-bacterial multi-fiber blended woven fabric has the excellent advantage of being resistant to mould and bacteria, soft in handfeeling, hygroscopic, breathable, capable of lowering noise, removing dust and insulating heat and the like.