The invention relates to a weight-losing and
stomach-occupying device and a manufacturing method thereof.The weight-losing and
stomach-occupying device is arranged in an inhalable mode and comprises a jelly substrate and
hydrogel microspheres at least partially wrapped in the jelly substrate, and each hydrogel
microsphere comprises a hydrogel
microsphere body and a waterproof degradable film wrapping the hydrogel
microsphere body; the material of the waterproof degradable film comprises
chitosan and
sodium alginate, the particle size of the hydrogel microsphere is 300-500 [mu] m, the waterproof degradable film can prevent the
volume expansion of the hydrogel microsphere body in the jelly matrix, and the waterproof degradable film can be decomposed in a
gastric acid environment to
expose the hydrogel microsphere body wrapped in the waterproof degradable film, so that the size of the hydrogel microsphere body is reduced, and the hydrogel microsphere body is protected. The hydrogel microsphere body absorbs water to swell,
stomach occupying is achieved,
gastric emptying is prolonged,
food intake is reduced through stomach occupying, the weight losing effect is achieved, and the weight losing and stomach occupying device is free of a rigid mechanical structure, has the amorphous characteristic, is smaller in compression and stimulation on the stomach, has
flavor and can achieve the weight losing function when being taken, and the weight losing and stomach occupying device is suitable for being used for people. And a user can use the device more comfortably, so that the acceptability is higher, and the compliance of the user is improved.