30 results about "Gastric bypass" patented technology

Methods and devices for simulating a gastric bypass and reducing the volume of the stomach involve placing a tubular liner along the lesser curve of the stomach cavity. Also, methods and devices for slowing gastric emptying involve placing valves within the stomach cavity near the gastrointestinal junction and/or the pylorus. These methods and devices may prevent a patient from drinking and eating large volumes at one time and from eating slowly all day.

Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.

A device (10) for treatment of obesity of a patient comprises an annular element (12) having a relatively large outer boundary and a relatively small inner boundary, and an elongated flexible tube (14) extending from the relatively small inner boundary of the annular element to a distal end. The relatively large outer boundary is adapted to be attached to an inner wall of a stomach (100) of a patient, such that the annular element divides the stomach (100) into two chambers, an esophagus-end chamber close to an esophagus of the patient, and a pylorus-end chamber close to a pylorus of the patient. The invention also provides a method for treatment of obesity of a patient which includes inserting an annular element having a relatively large outer boundary and a relatively small inner boundary into a stomach of the patient, and attaching the relatively large outer boundary of the annular element to an inner circumference of the stomach of the patient.

Devices and methods for tissue acquisition and fixation, or gastroplasty, are described. Generally, the devices of the system may be advanced in a minimally invasive manner within a patient's body, e.g., transorally, endoscopically, percutaneously, etc., to create one or several divisions or plications within the hollow body organ. Such divisions or plications can form restrictive barriers within a organ, or can be placed to form a pouch, or gastric lumen, smaller than the remaining stomach volume to essentially act as the active stomach such as the pouch resulting from a surgical Roux-En-Y gastric bypass procedure. Moreover, the system is configured such that once acquisition of the tissue by the gastroplasty device is accomplished, any manipulation of the acquired tissue is unnecessary as the device is able to automatically configure the acquired tissue into a desired configuration.

An endoscopic device separates ingested food from gastric fluids or gastric fluids and digestive enzymes, to treat obesity. In a particular embodiment a gastric bypass stent comprises a tubular member and two or more stent members defining a lumen. The tubular member has a substantially liquid impervious coating or covering and one or more lateral openings to permit one-way liquid flow.

An anastomotic ring device for forming a hollow rivet (ring) attachment between tissue lumens facilitates laparoscopic or endoscopic implantation by including features that facilitate actuation from a stressed, generally cylindrical shape. Economical manufacturer is achieved by weaving open ended strands into a generally cylindrical stent shape that is imparted with a Shape Memory Effect (SME) to actuate to a hollow rivet (ring) shape. Alternatively or in addition to SME inherent in the woven strands, an actuating force may be received from a helical spring element incorporated into the ring. Self-actuating ring devices are enhanced by forming woven strands into petals that diverge from opposing petals such that the strands encounter less friction when actuating. Each of these features alone or in combination enhance clinical use of anastomotic ring devices, such as a bariatric gastric bypass procedure.

Devices and methods for deploying an anastomotic stent between portions of the gastro-intestinal (GI) tract are disclosed. The anastomotic stents are configured to atraumatically engage the tissue walls and to permit the flow of fluid, partially digested food, and food. The stents can be deployed using endoscopic catheter devices, laparoscopic tools, and combinations of both endoscopic tools and laparoscopic tools. Examples of anastomoses include anastomoses between the stomach and a portion of the intestines such as the jejunum. Anastomoses can also be formed between two closed ends of the intestines, such as two closed ends of the colon formed during a colon resection procedure. Anastomoses can also be formed between a fundal pouch formed during a gastric bypass procedure and the jejunum. Laparoscopic tools are disclosed to deploy a stent by selectively removing a radial restraint on a self expanding stent with the restraint removed through the laparoscopic access points.

The invention relates to the production of a vertical gastric reservoir for the surgical treatment of morbid obesity. The reservoir consists of a clamp having two plates articulated at the lower end thereof and an automatic closing system in the upper part thereof, reinforced with a sealing system. Both plates are provided with two extensions (one at each end of the instrument) on the right-hand edge thereof. Both extensions are provided with two openings that are used to fix the instrument to the stomach wall. Application of the instrument and the technical solution provided are as follows: the substitution of metal staples which are subsequently eliminated in between 15% and 20% of patients and which result in failure of the vertical band gastroplasty operation. The instrument could also be used for producing small gastric reservoirs used for gastric bypass with minor curvature instead of metal staples.

Devices and methods for achieving weight loss in obese and morbidly obese patients are disclosed. The invention combines a gastric and/or small bowel bypass (in which ingested food bypasses the stomach and, optionally, at least a portion of the small bowel) and a satiety device in the form of one or more expandable chambers, that tend to induce a feeling of satiety after the patient has consumed a relatively small amount of food. This combination of gastric and/or small bowel bypass and satiety structure may be delivered and removed using minimally invasive procedures such as an endoscope. In some instances, the gastric and/or small bowel bypass device itself can form the satiety structure. In other devices, the gastric bypass may be independent of the satiety structure (which may be provided as one or more expandable chambers).

An improved gastric bypass prosthetic (GBP) device and an improved GBP fixation device, as well as a GBP kit for the surgical treatment of obesity. In one form, a gastric bypass prosthetic (GBP) device of the invention includes a optional flexible tube extending along a central axis from a proximal end to a distal end, and having a tubular tissue fixation portion at or near said proximal end. The tissue fixation portion extends along the central axis between a proximal end and a distal end of the tissue fixation portion, and has an annular outer surface between the proximal end and the distal end of the tissue fixation portion.

A system and method for endoscopically forming an anastomosis between two naturally adjacent points in the digestive tract. The system and method utilizes elongate magnetic devices that, when connected across a tissue boundary, necrose tissue until an anastomosis forms and the devices are passed naturally. Despite the elongate shape of the devices, the resulting anastomosis is substantially round. As such, round anastomoses can be formed having increased diameters merely by increasing the lengths of the devices, obviating the need for wider endoscopes.

Disclosed herein is a novel surgical instrument particularly adapted for use in surgeries involving a circular anastomosis stapler, and methods of using same. The subject instrument allows for the easy manipulation of an anvil of a circular stapler during surgery, to allow for improved placement of the anvil. The subject instrument and methods provide an improved gastric bypass technique which alleviates the need to pass the anvil down the esophagus, or through an incision in the upper stomach portion.

The invention provides pharmaceutical compositions, methods for the treatment of, and related diagnostics and computer-implementable systems that relate to, the treatment of a variety of metabolic syndromes, including hyperlipidemia, weight gain, obesity, insulin resistance, hypertension, atherosclerosis, fatty liver diseases and certain chronic inflammatory states. In an additional aspect of the invention, compositions and methods of treatment are calibrated to the ileal brake response to surgical intervention e.g. Roux-en-Y gastric bypass (RYGB)) as both activate the ileal brake, which acts in the gastrointestinal tract and the liver of a mammal to control metabolic syndrome manifestations and thereby reverse or ameliorate the cardiovascular damage (atherosclerosis, hypertension, lipid accumulation, and the like) resulting from progression of metabolic syndrome. The net benefit is the potential to treat all of the common manifestations of metabolic syndrome, including Type 2 diabetes and obesity, with one medicament, which contains glucose as an activation agent for the ileal brake. The ileal brake is the controller for progression of metabolic syndrome, and both RYGB surgery and the oral formulation act beneficially on the metabolic syndrome manifestations via this pathway. Disclosed as well are combination medicaments that act synergistically on the ileal brake and the manifestations of metabolic syndrome.

In other aspects, the invention provides ileal brake hormone releasing compositions, methods of treatment, diagnostics, and related systems useful in selective control of appetite, stabilizing blood glucose and insulin levels, and treating gastrointestinal disorders in a similar manner to RYGB surgery, but having at least 20% of the potency to stimulate the hormonal response of the ileal brake of humans.

The invention discloses a multi-layer coating type essential oil organic acid compound feed additive and a preparation method and application thereof. The additive comprises core particles including plant essential oil and organic acid, a middle coating layer including casings and organic acid and a gastric bypass coating layer from interior to exterior. By means of the multi-layer coating technology, plant essential oil and organic acid are combined, the novel coating type feed additive is obtained through the reasonable ratio, the additive can effectively pass through gastric acid and is slowly released in an animal intestinal tract, and therefore effective ingredients of the product can reach the animal intestinal tracts, the physiological and immunity effects are achieved, meanwhile, aserum biochemistry index can be improved, the body immune organ index is increased, the pH value of the content of the gastrointestinal tract is lowered, growth of harmful microbes is controlled, thebalance of the intestinal tract microorganism flora is kept, the small intestinal tract form is improved, the piglet intestinal tract mucous membrane permeability is improved, the intestinal mucosa barrier is protected, and the utilization rate of nutrient substances is increased, so that the animal body growth is promoted, and the production performance is improved.

The present invention relates to a device for implementing an explorable stomach gastric bypass apt to be implanted in a patient who needs it. In particular, such device comprises a main body having at least one elastic portion made of silicone material and a covering element of the main body itself that in turn comprises an extensible portion. The extensible portion is positioned at the elastic portion and characterizes in that it comprises an excess of material compared to the size of the elastic portion itself.

A gastric bypass device may include a first portion with an opening sized for receiving GI contents within an esophagus of the gastrointestinal tract, where a proximal end of the first portion includes first diameter, and where the first portion includes a first stent for anchoring the proximal end of the first portion. The gastric bypass device may also include a second portion located distally of the first portion, where the second portion is in fluid communication with the first portion, and where the second portion has an enlarged section with a second diameter that is at least about 150% as large as the first diameter.

The invention provides compositions, methods, and diagnostics for the treatment of metabolic syndromes. In an additional aspect of the invention, compositions and methods of treatment are calibrated to mimic the ileal brake response resulting from surgical intervention, e.g. RYGB, to control metabolic syndrome manifestations and thereby reverse or ameliorate the cardiovascular damage (atherosclerosis, hypertension, lipid accumulation, and the like) resulting from progression of metabolic syndrome. Combination medicaments that act synergistically on the ileal brake and the manifestations of metabolic syndrome are also disclosed.