11 results about "Gastric emptying" patented technology

This invention discloses a method and apparatus for modeling the gastric emptying characteristics of compressed dry food. The method includes: obtaining a set of gastrointestinal digestive enzyme concentration ranges; the set of gastrointestinal digestive enzyme concentration ranges includes salivary amylase concentration range, pepsin concentration range, and pancreatic enzyme concentration range; based on the set of gastrointestinal digestive enzyme concentration ranges, performing measurement processing on the compressed dry food to obtain a set of gastric retention rate values; and performing gastric emptying characteristic modeling on the set of gastric retention rate values ​​to obtain a set of gastric emptying models.

The application relates to a composition for treating reflux esophagitis and application thereof. The composition comprises the following components in parts by weight: 2-8 parts of scutellaria baicalensis, 3-7 parts of licorice, 5-10 parts of beeswax and 80-120 parts of vegetable oil. The composition for treating reflux esophagitis contains scutellaria baicalensis, licorice, beeswax and vegetable oil, and through mutual cooperation among the components, the drug prepared from the composition can significantly increase the plasma motilin level of a patient, further increase the pressure of the lower esophageal sphincter, promote gastric emptying and prevent acid reflux, promote the recovery of reflux esophagitis, the esophagus of the patient is obviously improved, and no adverse reaction is found; meanwhile, the content of lipid peroxide can be obviously reduced, the activities of superoxide dismutase and glutathione peroxidase are increased, the esophageal mucosa is protected and treated, the pathological changes of the esophagus are obviously improved, and the treatment effect is excellent.

The present invention relates to Lacticaseibacillus paracasei HP7 with preventive or alleviative efficacy for functional dyspepsia and uses thereof. The composition comprising the Lacticaseibacillus paracasei HP7 strain (accession number: KCTC 13143 BP) of the present invention as an active ingredient was confirmed to increase expression of intestinal tight junction genes, improve gastrointestinal peristalsis and gastric emptying effects, enhances gastric weight and gastric emptying levels associated with gastric emptying, and significantly increase blood hormone levels related to digestive activity, thereby improving dyspepsia.

The application discloses a kind of for skin source fermentation food flavour substance dynamic evaluation method and bionic digestion device.The bionic digestion device includes bionic stomach module and flow path system, bionic stomach module is connected with flow path system;Bionic stomach module is connected with gastric emptying regulation module by flow path system;Gastric emptying regulation module is connected with bionic small intestine module, and the digestion product in bionic stomach module is transported to bionic small intestine module to simulate gastric emptying process;Digestion liquid supplement module is connected with bionic stomach module and bionic small intestine module;Detection module is installed in bionic stomach module, gastric emptying regulation module, bionic small intestine module and flow path system;Sampling module is connected with flow path system, and the side deviating from flow path system is connected with flavour response detection unit.By establishing continuous bionic digestion system, the simulation degree of bionic digestion system to human real digestion process is improved, and the continuous evaluation of flavour change of skin source fermentation food in digestion process is realized.

This invention discloses a linear maltodextrose energy gel and its preparation method, belonging to the field of functional food technology. Using linear maltodextrose with a purity greater than 95% as the basic raw material, the prepared linear maltodextrose energy gel significantly prolongs the exhaustive swimming time of mice by 85.61%, reduces serum lactate by 38.43% and urea nitrogen by 42.67% after exhaustive exercise, and increases liver glycogen by 98.30% and muscle glycogen reserves by 115.63%, effectively alleviating exercise fatigue and reducing bodily damage. The energy gel has a uniform texture, suitable sweetness and viscosity, good palatability when swallowed, and a refreshing aftertaste without any off-flavor. In preparing high-energy-density energy gels, good viscosity and taste can be maintained without adding hydrocolloids. This reduces production costs and simplifies the production process while avoiding the adverse effects of hydrocolloids on gastric emptying speed and sticky texture, resulting in a higher quality energy gel.

The application discloses a kind of rich in wheat oligopeptide compressed dry food digestion performance evaluation method and device, the method comprises: using in vitro dynamic human gastrointestinal digestion system, not containing wheat oligopeptide compressed dry food and rich in wheat oligopeptide compressed dry food are respectively simulated digestion processing, respectively measured to obtain first measurement index set and second measurement index set;Each type of measurement index set, including gastric emptying curve, protein digestion rate sequence, amino acid composition value sequence, fat bioavailability sequence;The gastric emptying curve includes several discrete points;The first measurement index set and second measurement index set are preprocessed, and obtain preprocessed index information set;The preprocessed index information set is evaluated and processed, and obtains the digestion performance evaluation value of rich in wheat oligopeptide compressed dry food.

Described herein are methods and compositions for treatment of diabetes and / or obesity. Bitter oligopeptide molecules formulated for enteric delivery modulate signals involving receptors facing the lumen of the gastrointestinal tract, said signaling related hormones such as glucagon-like peptide-1 (GLP-1) and peptide tyrosine-tyrosine (PYY) that involve inhibition of gastric emptying and appetite. As a novel way to treat diabetes with limited adverse effects the described invention uses body's own endocrine system to treat diabetes, which is an advantage over current therapies that may simply provide disease management without cure or require more radical approaches such as surgical intervention.

This invention discloses the application of Amomum villosum extract in the preparation of drugs for the prevention and treatment of functional dyspepsia, belonging to the field of biotechnology. The extract, when applied to the prevention and / or treatment of functional dyspepsia, can increase plasma levels of motilin (MTL) and gastrin (GAS), promote gastrointestinal motility, significantly improve gastric emptying rate in functional dyspepsia model mice, improve pathological damage to gastric tissue, restore mitochondrial function in gastric tissue, and regulate the expression of related factors in gastric tissue. Even at low doses, it can effectively increase plasma MTL and GAS levels in loperamide hydrochloride-induced functional dyspepsia model mice, improve gastric emptying rate, effectively improve pathological damage to gastric tissue in these mice, and regulate the expression of related factors in the gastric tissue. The raw materials of this invention are derived from natural products, are easy to collect, and have high safety.

This invention discloses a traditional Chinese medicine composition for the prevention and / or treatment of gastric ulcers and / or their complications. By weight, the composition comprises: 2-6 parts of Atractylodes lancea, 2-6 parts of Poria cocos, 1-4 parts of Magnolia officinalis, 2-6 parts of Aucklandia lappa, 1-4 parts of Lindera strychnifolia, 1-4 parts of Cyperus rotundus, 1-4 parts of Alpinia officinarum, 1-4 parts of Amomum villosum, 1-4 parts of Coix lacryma-jobi, 1-4 parts of Citrus reticulata peel, 1-4 parts of Citrus medica, 1-4 parts of Crataegus pinnatifida, 1-4 parts of Massa fermentata, 1-4 parts of Hordeum vulgare, 1-4 parts of Gallus gallus domesticus gizzard lining, 1-4 parts of Bletilla striata, 2-6 parts of Paeonia lactiflora, 2-6 parts of Corydalis yanhusuo, 1-4 parts of Cinnamomum cassia, and 1-4 parts of Piper longum. The complications are selected from one or more of the following: pain, inflammation, and delayed gastric emptying. This traditional Chinese medicine composition is safe, effective, and has a simple and efficient preparation method with controllable quality. It exhibits significant anti-inflammatory, analgesic, and gastric motility-promoting effects, and can reduce the colonization of Helicobacter pylori in the stomach. It also has significant therapeutic effects on gastric ulcers induced by different factors (Helicobacter pylori infection, pyloric ligation, and nonsteroidal anti-inflammatory drugs).

The application relates to the technical field of intelligent health management, and discloses a children obesity individualized meal recommendation system fused with a knowledge graph, which comprises the following modules: a graph construction module used for establishing food nodes with initial half-lives and volumes and directed edges with time sequence shielding coefficients; a constraint solving module used for extracting a candidate subgraph meeting a heat standard and arranging to generate multiple eating topological directed paths; a state machine deduction module used for stepping along the paths and calculating actual half-lives based on the time sequence shielding coefficients; a time sequence integral module used for obtaining satiety decay integrals by discretely accumulating residual volumes based on the actual half-lives; and a recommendation output module used for converting the path with the largest integral into a food material list and outputting a recommended eating instruction. The application quantifies the intervention of an eating order on gastric emptying, outputs a scheme with the longest satiety through optimization, and improves the scientificity and compliance of the children obesity individualized meal recommendation fused with the knowledge graph.