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Anchored non-piercing duodenal sleeve and delivery systems

a duodenal sleeve and anchored technology, applied in the field of duodenal sleeves, can solve the problems of not being able to keep weight, surgery might not be an option for every obese individual, etc., and achieve the effect of convenient removal

Inactive Publication Date: 2012-04-19
APOLLO ENDOSURGERY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a transorally inserted, intragastric device for the treatment of obesity. The device includes a sleeve for placement in the duodenum and a stomach anchoring member with a collapsed, delivery size, and an expanded, deployed size larger than a pyloric sphincter. The sleeve is axially collapsible / expandable and has exterior ribs to resist movement within the duodenum in one direction. The device also includes a duodenal anchoring member with a collapsed, delivery size, and an expanded, deployed size larger than a pyloric sphincter. The device is formed of a material that will resist structural degradation over a period of at least six months within the gastrointestinal tract. The device can be used to treat obesity by reducing the amount of food consumed and promoting weight loss.

Problems solved by technology

Millions of obese and overweight individuals first turn to diet, fitness and medication to lose weight; however, these efforts alone are often not enough to keep weight at a level that is optimal for good health.
However, surgery might not be an option for every obese individual; for certain patients, non-surgical therapies or minimal-surgery options are more effective or appropriate.

Method used

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  • Anchored non-piercing duodenal sleeve and delivery systems
  • Anchored non-piercing duodenal sleeve and delivery systems
  • Anchored non-piercing duodenal sleeve and delivery systems

Examples

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Embodiment Construction

[0032]The present invention is directed to intragastric devices for passively treating obesity by limiting nutrient absorption / caloric assimilation. Furthermore, the exemplary device described herein may affect the rate of stomach emptying. The term “passive” refers primarily to a lack of any moving parts within the devices, but in general to the inert nature of the various devices.

[0033]FIG. 1 illustrates an exemplary intragastric obesity treatment implant 20, but also illustrates the anatomy of the human stomach, which will be described first. The major function of the stomach S is to temporarily store food and release it slowly into the duodenum D. The esophagus E extending downward from the mouth connects to the stomach via esophageal sphincter ES, which regulates flow food into the stomach cavity. The cardia C surrounds the superior opening of the stomach. The rounded portion superior to the body B and adjacent the cardia is the fundus F. Inferior to the fundus is the large cen...

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PUM

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Abstract

An intragastric implant for obesity treatment is disclosed. The device delays digestion by providing a duodenal sleeve, and may also slows gastric emptying by limiting flow through the pyloric sphincter. The implant includes an elongated axially-compressible duodenal sleeve having a non-tissue-piercing anchor on a proximal end sized to lodge within the duodenal bulb. The anchor may have oppositely-directed anchoring flanges to resists migration in both directions. The sleeve may also have barbed ribs to resist proximal movement back up into the stomach. A method of implant includes collapsing / compressing the device and transorally advancing it through the esophagus to be deployed within the duodenum. A dissolvable jacket may constrain the implant for delivery and naturally dissolve upon implant. Removal of the implant may occur in the reverse.

Description

RELATED APPLICATIONS[0001]The present application claims priority under 35 U.S.C. §119 to U.S. Provisional Application No. 61 / 479,714, filed Apr. 27, 2011, to U.S. Provisional Application No. 61 / 485,009, filed May 11, 2011, and to 61 / 394,592, filed Oct. 19, 2010, the disclosures of which are incorporated by reference herein.FIELD OF THE INVENTION[0002]The present invention is directed to intragastric devices used for the treatment of obesity, and in particular to duodenal sleeves having a non-piercing anchor and delivery systems therefor.BACKGROUND OF THE INVENTION[0003]Over the last 50 years, obesity has been increasing at an alarming rate and is now recognized by leading government health authorities, such as the Centers for Disease Control (CDC) and National Institutes of Health (NIH), as a disease. In the United States alone, obesity affects more than 60 million individuals and is considered the second leading cause of preventable death. Worldwide, approximately 1.6 billion adul...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B17/11
CPCA61F5/0079A61F5/0076
Inventor BABKES, MITCHELL H.DOMINGUEZ, ZACHARYMUDD, CHRISTOPHER S.
Owner APOLLO ENDOSURGERY INC
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