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130 results about "Human stomach" patented technology

Shell-broken ganoderma spore powder and particle combination and preparation method thereof

The invention discloses shell-broken ganoderma spore powder and particle combination and a preparation method thereof. Shell-broken ganoderma spore powder is extracted, centrifuged, concentrated, dried and crushed to obtain the shell-broken ganoderma spore powder and particle combination, the content of crude polysaccharide in the shell-broken ganoderma spore powder and particle combination is 10-20g / 100g, and the content of total triterpene in the shell-broken ganoderma spore powder and particle combination is 4-10g / 100g. The shell-broken ganoderma spore powder and particle combination has the advantages that immunities are enhanced, radiation hazards are reduced in an auxiliary manner, the shell-broken ganoderma spore powder is treated by the aid of a special process, the content of effective components are increased, nutrient components in the effective components can be effectively absorbed by human bodies, functions of the shell-broken ganoderma spore powder are effectively played, the shell-broken ganoderma spore powder is conveniently carried and taken, the shell-broken ganoderma spore powder and particle combination has an inhibiting effect on zebra fish human stomach cancer transplantation tumors, human lung cancer transplantation tumors and human lymphocyte cancer transplantation tumors, and the shell-broken ganoderma spore powder and particle combination has a strong inhibiting effect on the zebra fish human stomach cancer transplantation tumors and the human lymphocyte cancer transplantation tumors.
Owner:ZHEJIANG SHOUXIANGU PHARMA CO LTD +1

Ingestible capsule for the phototherapeutic treatment of infections

An ingestible capsule arranged, in use, to cross a human stomach for carrying out a phototherapic treatment arranged to combat an infection due to the presence of the bacterium Helicobacter pylori, said ingestible capsule comprising at least one primary light source arranged to emit an electromagnetic phototherapic wave having a wavelength λ1, at least one auxiliary light source arranged to emit an electromagnetic phototherapic wave having a wavelength λ2, a wrapper arranged to contain said or each primary light source and said or each auxiliary light source, said wrapper being at least partially transparent to said wavelengths λ1 and λ2, a control unit arranged to selectively activate said or each primary light source and/or said or each auxiliary light source, and at least one energy source arranged to provide energy for feeding said control unit and/or said light sources. In particular, 400 nm<λ1<525 nm and 525 nm<λ2<650 nm. Furthermore, said control unit is configured to receive an information of position reporting in real time an area of said stomach crossed by said ingestible capsule; to determine, known said information of position, a wavelength, a dosage and a duration of administration of said electromagnetic phototherapic waves for an optimal phototherapic treatment of said area of said stomach; to selectively activate said or each primary light source and/or said or each auxiliary light source to provide said optimal phototherapic treatment of said area of said stomach.
Owner:PROBIOMEDICA SRL

Ginkgo flavone and lactone -cyclodextrin derivate inclusion complex and preparation method thereof

The invention discloses an extract of Ginkgo Biloba leaves-cyclodextrin derivative inclusion compound and a preparation method thereof, which is prepared from 10 to 24 percent of total flavonol glycoside, 2 to 6 percent of terpene lactone and 70 to 88 percent of cyclodextrin derivative and auxiliary materials, according to the weight percentage; the preparing method comprises the following steps: dissolving cyclodextrin derivative in water, adding extract of Ginkgo Biloba leaves; stirring for 6 to 8 hours; reducing the pressure and vacuum drying at the temperature of 55 to 65 DEG C; and obtaining the extract of Ginkgo Biloba leaves-cyclodextrin derivative inclusion compound in a solid grinding way. The invention adopts an inclusion technology to greatly enhance the dissolubility and the dissolution of the ginkgo leaves in the water, to enhance the absorption in human stomach and intestine, and to simultaneously greatly increase the stability of the principal components in the extract of Ginkgo Biloba leaves, the extract of Ginkgo Biloba leaves and terpene lactones after being processed by adopting the inclusion technology. The extract of Ginkgo Biloba leaves, after being processed by adopting the inclusion technology, is 1 to 2 times higher than the ordinary preparation in bioavailability, and can be used for preparing the drugs for improving the disease of cardio-cerebrovascular systems, and preventing and remedying coronary heart diseases.
Owner:陈建海

Visualized bionic digestion reactor for stomach body

The invention provides a visualized bionic digestion reactor for a stomach body and belongs to the field of bionic reactors. The visualized bionic digestion reactor comprises a first adaptor, a secondadaptor, reaction bottles, a latex bionic stomach, a sampling bottle and a constant-temperature circulating water groove, wherein the reaction bottles comprise a vertical straight-type reaction bottle, a spherical reaction bottle and a horizontal straight-type reaction bottle; the latex bionic stomach comprises a latex bionic stomach body, a latex bionic stomach antrum and a latex bionic pylorus,which are placed in the vertical straight-type reaction bottle, the spherical reaction bottle and the horizontal straight-type reaction bottle respectively; the constant-temperature circulating watergroove is connected with input pipes and output pipes on the reaction bottles through silica gel pipes; valves are connected with the middles of the silica gel pipes and are used for controlling thecirculating water flow. The visualized bionic digestion reactor for the stomach body, provided by the invention, is simple in structure, convenient to detach, good in sealing performance and strong invisibility, can be used for vividly simulating peristalsis of a human stomach and has good digestion simulation repeatability.
Owner:无锡南源生物科技有限公司

Heavy metal bioavailability testing device and method for simulating human gastric digestion characteristics

The invention discloses a heavy metal bioavailability testing device and method for simulating human gastric digestion characteristics. The testing device comprises a container for simulating gastricdigestion reaction; a gastric digestion reaction feed module connected with the container for simulating the gastric digestion reaction and used for supplementing liquid and gas required for simulating the human gastric digestion in the container, thereby simulating the human gastric juice secretion and anaerobic digestion environment; a stirring module located at the bottom of the container for simulating the gastric digestion reaction and used for stirring the liquid in the container, thereby simulating the peristole of the human stomach; a temperature control module connected with the container for simulating the gastric digestion reaction and used for controlling the temperature of the liquid in the container, thereby simulating the temperature environment of the human stomach; a monitoring module located in the container for simulating the gastric digestion reaction and used for monitoring the temperature and pH value of the liquid in the container; and a digestion reaction collection module communicating with the container for simulating the gastric digestion reaction, and used for simulating the gastric emptying and collecting the digested liquid in the container.
Owner:JIANGSU PROVINCIAL ACAD OF ENVIRONMENTAL SCI

Traditional Chinese medicine extract method featuring combined utilization of all biomimetic digestion technology and cell membrane biomimetic solid phase extraction technology

ActiveCN101961355AMaintain conformationMild reaction conditionsPlant ingredientsIntestinal structureDuodenal juice
The invention provides a traditional Chinese medicine extract method featuring combined utilization of the all biomimetic digestion technology and the cell membrane biomimetic solid phase extraction technology. The traditional Chinese medicine extract method mainly comprises the following steps: adding corresponding biomimetic digestive juice (simulated saliva, simulated gastric fluid, simulated duodenal juice and simulated bile) according to components and quantities of the digestive juice secreted by different digestive organs in a certain period of time in different digestive phases; then reasonably arranging digestion time of different digestive phases according to evacuation time of different dosage forms of the traditional Chinese medicine in human digestive organs to obtain all biomimetic digestive juice; and then obtaining a monolayer liposome loaded with a traditional Chinese medicine active constituent bundle according to distribution and absorption states of monolayer liposome-water distribution system simulated all biomimetic digestive juice in human stomach and intestines. In the invention, the all biomimetic digestion technology and the cell membrane biomimetic solid phase extraction technology are jointly adopted, the reaction conditions are mild and the method has the beneficial effects of maintaining conformation of the natural products and previous potency of the active constituents.
Owner:MINNAN NORMAL UNIV

External drug for slimming and preparation method thereof

The invention relates to an external drug for slimming and a preparation method thereof. The external drug is prepared from, by weight, 30-70 parts of rheum officinale, 20-30 parts of purple perilla, 15-35 parts of safflowers, 20-40 parts of hawthorn fruits, 10-20 parts of semen cassia, 30-50 parts of apocynum venetum, 20-35 parts of rhizoma anemarrhenae, 10-30 parts of mint leaves, 15-35 parts of coix seeds, 15-25 parts of honeysuckle, 5-10 parts of pericarpium citri reticulatae and 25-40 parts of lemon grass. The preparation method comprises the steps that the pericarpium citri reticulatae, the safflowers, the apocynum venetum and the mint leaves are extracted through supercritical fluid for use; the raw materials except the pericarpium citri reticulatae, the safflowers, the apocynum venetum and the mint leaves are chopped, vacuum drying is performed, and then a product and extraction essential oil are mixed on the basis of the weight ratio being 8:2. According to the external drug for slimming, the efficacy of the drug enters the human body from the Shenque point through hot compress and acts on the waist and abdomen where damp toxin and fat are accumulated, and the external drug can achieve detoxification, remove stasis and achieve natural weight loss, and is convenient to use and rapid in action, the weight will not bounce back, no toxic or side effect is generated, and meanwhile harm caused by oral drugs to human stomach functions is avoided.
Owner:广州康其美业生物科技有限公司

Application of wogonin in the preparing of medicine for treating gastric cancer

The invention discloses an application of wogonin to prepare stomach cancer medicine in pharmacy domain, which is characterized by the following: possessing distinctive growth inhibitory action of the wogonin for human stomach cancer MGC803 bare mouse transplanting tumor. This invention provides better choice for stomach cancer patient.
Owner:CHINA PHARM UNIV +1

A kind of camel velvet transfer protein and its preparation method and application

The invention discloses a peganum harmala lipid transfer protein (PHP) and relates to the preparation and use of new protein with antifungal, anticancer and antivirus activities. The method uses seeds of a peganum harmala plant as raw materials and comprises the following steps: preparing a coarse product, performing cationic exchange chromatographic separation and purifying by using a molecular sieve; and gradually separating and collecting a purified component having antibacterial activity, dialyzing, desalting, freeze-drying and thus, obtaining purified PHP. In the invention, a filter paper disc agar diffusion method is adopted, and researches prove the protein has growth inhibiting effect on five plant pathogenic fungi, namely alternaria alternate, penicillium degitatum, rhizopus stuolonifer, magnaporthe grisea and penicillium italicum. An 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method proves that the protein has inhibiting effect on proliferation of human esophageal carcinoma cell Eca109, human cervical cancer cells HeLa, human stomach cancer cells MGC-7, mouse melanoma cells B16 and the like. The protein can inhibit the activity of human immunodeficiency virus 1 (HIV-1) reverse transcriptase. The protein can be used for developing medicines for resisting agricultural pathogenic fungi, tumors and viruses.
Owner:XINJIANG UNIVERSITY

Compound loquat buccal tablets and preparation method thereof

The invention relates to compound loquat buccal tablets and a preparation method thereof. Based on loquat, olive, almond, tangerine peel, platycodon grandiflorum, mulberry, chrysanthemum, licorice and the like are added; and the buccal tablets have main effects of clearing heat from throat, drying damp, eliminating phlegm, relieving cough and asthma, dispelling wind and dissipating heat, and relieve the symptoms such as cough with lung heat, mouth parching and tongue scorch, swelling and pain in throat, phlegm obstruction and asthma caused by wind heat. The buccal tablets are prepared from medicinal and edible materials, and are exquisite in formula, safe and effective by extraction and concentration of active ingredients and convenient to carry and use; and because the active medicinal ingredients can be directly absorbed through oral mucosa in the oral taking process, loss of nutrition and medicinal ingredients absorbed by organs such as human stomach, intestines and liver is avoided, and the absorption and utilization rate of the medicinal ingredients is improved. The compound loquat buccal tablets have important value and make great contribution to clinical health care and the like, and have comprehensive effects which are superior to those of similar products in the market; and a new optional formulation is provided for clinical patients.
Owner:FUJIAN AGRI & FORESTRY UNIV

Lactobacillus salivarius and pharmaceutical application thereof

The invention discloses lactobacillus salivarius which is separated from human gastric mucosa and can be used for preventing and treating stomach diseases caused by helicobacter pylori. The preservation number of lactobacillus salivarius is CGMCC NO.8379. The invention further provides a product for preventing and / or treating stomach diseases caused by helicobacter pylori. The product comprises active components comprising the lactobacillus salivarius. In addition, the invention further provides a product for inhibiting helicobacter pylori. The product comprises active component comprising the lactobacillus salivarius. The application shows that the selected lactobacillus salivarius can not only be well applicable to the human stomach environment and has very high functions of preventing helicobacter pylori growth, adhesion and planting, but also can remarkably reduce inflammation caused by helicobacter pylori in stomach tissue of mice.
Owner:ARMY MEDICAL UNIV
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