388 results about "Duodenum" patented technology

Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.

Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the duodenum and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for attaching the device to the duodenum and an unsupported flexible sleeve to limit absorption of nutrients in the duodenum. The anchor can include a stent and/or a wave anchor and is collapsible for catheter-based delivery and removal.

A fixation device for holding stimulating electrodes in electrical contact with the wall of a portion of the gastrointestinal tract is provided. In one embodiment, the fixation device includes an expandable member that fixes the electrodes in electrical contact with the gastrointestinal tract wall. Also provided is an implantable device and method for controlling the opening and/or closing of the pylorus. In particular a device and method is provided for stimulating the duodenum to control the closing/and or opening of the pylorus. Finally, a method is provided for treating obesity by controlling the pylorus to retain food in the stomach for a desired period of time, among other things to provide a feeling of satiety and/or to reduce hunger. One aspect includes controlling the pylorus's contraction by electrical stimulation of the duodenum.

A system and method for treating nausea and vomiting are provided, including one or more electrodes (10, 12) applied on or under the skin, the electrodes being connected to an external current source (34). The electrodes can be implanted under the skin and connect to internal stimulator electronics (22), which can form a magnetic inductive link to the external current source (34). Alternatively, the electrodes can be placed on the skin and directly linked by wires to the external current source. As a further alternative, the vagus nerve can be directly stimulated in the neck, or the esophagus, stomach, duodenum, or intestines can be directly stimulated by magnetic stimulation. The electrodes can stimulate the vagus nerve in the neck to reduce nausea and vomiting, or can be arranged near the chest or abdomen, so as to stimulate the esophagus, stomach, duodenum or intestines. Because the current source is provided outside the body, it is not necessary to implant batteries or another power supply in the body.

An apparatus and a method for treating a weight disorder in a subject are provided. The apparatus comprising an implantable device such as an inflatable balloon and electrodes capable of sensing a physiological change associated with food ingestion or hunger and a mechanism adapted for directly stimulating a region such as the duodenum which is responsive to a gastrointestinal satiety agent, such a mechanism can be a drug reservoir containing a drug such as CCK or analogs thereof which is contained within an inflatable balloon being implantable in a stomach of the subject. The apparatus and method provided here combine synergistic approaches to limiting meal size, i.e., chemo and mechano receptor activation of vagal satiety stimuli, electric stimulation of specific vagal pathways and limitations of gastric space.

Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the stomach and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device to the stomach and a flexible sleeve to limit absorption of nutrients in the duodenum. The anchor is collapsible for endoscopic delivery and removal.

Pyloric valve corking devices and methods are described herein. The devices generally include an occluding member which expands from a first configuration to a larger second configuration and a bridging member extending from the occluding member. The bridging member has a length which passes at least partially through the gastric opening such that the occluding member obstructs the gastric opening, and wherein the length permits the occluding member to intermittently move relative to the gastric opening. A second occluding member may be attached to the distal end of the bridging member. The reduction in flow of gastric contents into the duodenum can be tightly regulated using a pump or valve. Otherwise, the flow can be passively regulated with the occluding device.

A gastrointestinal implant device is positioned in a patient's small intestine or rectum and produces an outward force that itself produces a distension signal which is a therapeutically useful neural or humoral signal that evokes satiogenic or weight loss effects by itself. The device may advantageously be placed in the duodenum adjacent the pylorus or in the jejunum, ileum or rectum. The distension signals may amplify chemosensory or mechanosensory signals such as enteroendocrine secretions within the patient. The device may be a mesh and include a low material density that allows for unrestricted chyme absorption within the small intestine and unrestricted chyme flow through the gastrointestinal system. A method includes inserting the device into the patient then either retrieving the device after treatment is complete or allowing a device formed of a biodegradable material to degrade in time after treatment is complete.

A semi-stationary balloon in the gastric antrum provided with an anchoring rod for inducing weight reduction in human beings is disclosed, a device for inducing a lesser appetite and early prandial satiety, said balloon being made of inflatable per-os medical grade silicone having a volume of up to 240 ml, with an average space of 120 ml to be filled with non-elastic fluid provided with radio-opaque contrast and dye, preferably methylene blue, so that the maximum diameter of 8 cm is reached after it is filled up with a volume of up to 240 ml and the average diameter of 6 cm with a volume of 120 ml, to be endoscopically placed inside the stomach (E); said intra-gastric balloon (1) being positioned in a semi-stationary way in the gastric antrum (GAC) and provided with an anchoring or duodenal rod (2) having a distal counter-weight (5) installed in the duodenum (D); particularly, the inner face of the pear-shaped medium portion of lesser diameter is coated with a malleable ribbon (f) that provides said balloon (1) with resistance and flexibility.

GERD is treated through a method and apparatus of stimulating the body organ to accelerate a discharge of contents from the duodenum of the patient to thereby encourage discharge of contents from the stomach of the patient across the pyloric valve and into the duodenum.

A method for treating a patient includes creating at least one incision to gain access to an petitoneal cavity, performing a gastric volume reduction procedure and introducing a device to prevent gastric contents from interacting with at least a portion of the duodenum.

A feeding tube apparatus, a kit containing the feed tube apparatus and method for intubating a patient to deliver the feeding tube apparatus to the desired location for delivering nutrients and/or medication are described herein. The feeding tube apparatus (10) contains at least a catheter (20) and a removable stylet (30), where the removable stylet contains one or more magnetic materials (32a-j). In one embodiment, the stylet contains more than one magnetic material in the form of a magnet stack (33). The feeding tube apparatus is used in combination with a suitable external magnet (40) which a medical practitioner can use to guide the feeding tube apparatus (10) through the intestinal tract. Optionally, the feeding tube apparatus contains additional components, such as a spring wire guide. The feeding tube apparatus is inserted into the patient's body and the external magnet (40) is applied to the patient's body within the minimum distance required to create a magnetic field between the external magnet (40) and the magnetic material(s) (32) located at the distal end (34) of the stylet (30) that is sufficiently strong to allow the external magnet to guide the catheter and stylet through the intestinal tract, and into the distal duodenum (470) of the small intestine. Once the catheter is placed in the desired location, the stylet is removed, thereby removing the magnetic material(s) from the feeding tube apparatus. This allows for the catheter to remain in place while the patient undergoes diagnostic testing, such as magnetic resonance imaging.

A gastrointestinal implant device comprises a sleeve for extending into the duodenum and an artificial valve for placement at the pylorus to control flow from the stomach into the duodenal sleeve. The implant device also comprises a support structure for the valve.

The present invention provides methods of treating overweight or obese patients with an inflatable weight control device that is implanted in the patient's digestive tract. A first method comprises the steps of providing the weight control device which includes an inflatable body having a first bulb, a second bulb, an intermediate portion, and an internal passageway extending from the first bulb through the intermediate portion and to the second bulb. The inflatable body includes a valve assembly that is grasped by the endoscope during insertion of the weight control device in the patient's pylorus. Next, the endoscope is used to position the weight control device within the pylorus such that the intermediate portion resides within the pyloric valve and the first bulb resides within the pyloric antrum. The weight control device is then inflated with the endoscope such that the first bulb engages an inner surface of the pyloric antrum to form an outlet obstruction within the pyloric antrum. This obstruction causes chyme to accumulate proximate the first bulb prior to entering the internal passageway where it is then transported through the body and discharged from the second bulb into the patient's duodenum. The accumulation of chyme in pyloric antrum and the stomach causes the patient to feel full and stop eating. Thus, the treatment method provides a gastric outlet obstruction that slows the passage of chyme into the duodenum and as a result, the patient feels full and stops eating after consuming relatively small portions.