10results about How to "Accelerate the accumulation process" patented technology

The invention relates to the field of nanometer friction power generation sensing technology and film material manufacturing, in particular to a high-friction-voltage hydroxyethyl cellulose sensing material and a preparation method thereof.The sensing material comprises three layers of structures which are an upper layer hydroxyethyl cellulose film, a polyvinylidene fluoride film and a lower layer hydroxyethyl cellulose film from top to bottom, the HEC film with aramid nanofiber introduced into the outer layer serves as a friction layer and a mechanical supporting layer, the PVDF film in the middle serves as an electrostatic retention phase, and organic combination of electrostatic coupling and charge storage is achieved. According to the invention, a new thought is provided for the development of a friction nanometer power generation technology, and a more efficient and environment-friendly solution is provided for the application in the fields of wearable equipment, self-powered sensors and the like.

The invention provides a porous Fe / Cu nanoreactor with double insurance design and a preparation method and application thereof, and belongs to the technical field of biology. The porous Fe / Cu nano-carrier is firstly prepared and used for reducing toxic and side effects of chemotherapeutic drugs, pyridazinone micromolecule chemotherapeutic drugs IMB are loaded on the carrier, toxicity of IMB is further reduced through wrapping and targeting effects of 3F8 antibodies, targeted controllable slow release of the chemotherapeutic drugs is achieved through acid response of the porous Fe / Cu nano-carrier, and the effect of reducing toxic and side effects of the chemotherapeutic drugs is achieved. The double-insurance effect and the precise chemical kinetics treatment of melanoma are achieved. In the tumor acidic microenvironment, the porous Fe / Cu nano reactor with the double insurance design can specifically respond to the tumor acidic microenvironment, and controllable slow release of small molecule chemotherapeutic drugs is achieved. Meanwhile, through the targeting effect of the 3F8 antibody, targeted delivery and accumulation of small molecule chemotherapeutic drugs at the tumor site are enhanced, and the chemotherapeutic effect is enhanced.

The invention relates to the technical field of rice high-yield cultivation, and discloses a northern rice high-yield population construction and cultivation method based on light and temperature close planting regulation, comprising the following steps: S1, light, temperature and regional environment monitoring: collecting illumination and temperature data and soil and irrigation and drainage conditions of a northern rice planting region, and establishing a regional light and temperature change model; s2, variety matching and sowing period determination: combining the light and temperature sensitive characteristics of the rice variety with the monitoring data in the step S1. According to the method, on the basis of real-time light and temperature monitoring and a over-the-year big data model, the key growth period and the high light and temperature period of rice are accurately aligned, the advantages of sufficient illumination and large day and night temperature difference of northern rice areas are utilized to the maximum extent, and water, fertilizer and field management are adjusted by dynamically adapting to light and temperature changes; and for example, nutrient supply is optimized when illumination is insufficient, and cooling measures are taken at high temperature, so that the accumulation and transfer efficiency of photosynthetic products is remarkably improved, the problem of insufficient utilization of light and temperature resources in traditional cultivation is solved, and a material foundation is laid for high yield.

The present invention provides a safe and effective DDS technique that realizes higher accumulation in lesions and reduced accumulation in normal organs including the liver, and thus can afford sufficient therapeutic effects with smaller amounts of drugs. Specifically, a composition containing carbonate apatite particles loaded with a drug, wherein the particles have an average particle size of larger than 500 nm and not more than 1000 nm, primary particles are formed in the presence of a polyethylene glycol (PEG) derivative having one or more carboxylic acids or derivatives thereof or salts thereof at the ends thereof, and the PEG derivative is taken up in the primary particles, is provided.

The invention belongs to the technical field of vegetable fertilizers, and particularly relates to a method for promoting humification of kitchen waste compost. The method comprises the following steps: uniformly mixing kitchen waste serving as a composting raw material with a composting auxiliary material, and putting the mixture into a reactor for composting reaction; adjusting the initial carbon-nitrogen ratio of the mixed material to be 20-40 and the water content to be 50%-70%; the mass ratio of the compost raw material to the compost auxiliary material is 1: (2-4); in the mixing process of the compost raw material and the compost auxiliary material, adding charcoal into a reactor; adding mineral substances into the reactor when the reaction temperature is 50-60 DEG C; the addition amount of the mineral substances is 5%-15% of the total dry weight of the compost raw materials, the compost auxiliary materials and the biochar. The method for promoting humification of the kitchen waste compost provided by the invention can effectively solve the problems that the organic matters of the traditional kitchen waste compost are not stable enough and the humification efficiency is low.

The invention discloses a self-assembled polypeptide, a self-assembled polypeptide nano-material as well as a preparation method and application of the self-assembled polypeptide nano-material. The sequence of the self-assembled polypeptide is SRNLIDK [C14] ATGPAK [C14] DILNRS. The preparation method of the self-assembled polypeptide nano material comprises the following steps: dissolving self-assembled polypeptide in deionized water or a PBS (Phosphate Buffer Solution), and incubating; adding a hydrophobic anti-fibrosis drug solution into the incubated solution, and carrying out ultrasonic treatment; and then incubating to form a nano spherical skin-core structure of the self-assembled polypeptide coated hydrophobic anti-fibrosis drug. The self-assembled polypeptide nano material can be applied to preparation of medicines for resisting organ or tissue fibrosis. A plurality of PDGFR beta binding sites exist in the self-assembled polypeptide and can be specifically bound with PDGFR beta protein, so that it is guaranteed that the entrapped anti-fibrosis medicine is bound to activated hepatic stellate cells with high expression of PDGFR beta in a targeted mode, meanwhile, the polypeptide modifies an FAP-alpha response sequence, and the anti-fibrosis medicine can be responsively and specifically released in an FAP-alpha high expression area.

The invention relates to the technical field of application of radix astragali seu hedysari oral liquid, and particularly discloses application of a compound radix astragali seu hedysari oral liquid in the anti-fatigue effect of mice, which comprises the following steps: S1, preparing an intragastric solution, S2, carrying out grouped administration on the mice, S3, carrying out a weight-bearing exhaustive swimming test on the mice, S4, determining related indexes, and S5, carrying out statistical analysis. The compound radix astragali seu hedysari oral liquid can reduce glycogen consumption and BUN accumulation of exercise mice and prolong the exercise time of the mice, so that the compound radix astragali seu hedysari oral liquid has a certain anti-fatigue effect, and the compound radix astragali seu hedysari oral liquid consisting of the three traditional Chinese medicinal materials can be used as an antioxidant and a supplement for improving exercise tolerance, so that the anti-fatigue function is achieved; different doses of compound radix astragali seu hedysari oral liquid can reduce the accumulation of malonaldehyde, reduce the release of lactic dehydrogenase and creatine kinase into blood, increase the accumulation of superoxide dismutase and glutathione peroxidase, and relieve the muscle injury of mice with excessive movement.

The invention provides an application of an StMYB113b gene in regulating and controlling the epidermal color of a potato tuber. According to the invention, the key gene StMYB113b for regulating and controlling the formation of the red skin pigment of the potato tuber is found and cloned for the first time, and the gene can influence the skin color of the potato tuber by regulating and controlling the synthesis of an anthocyanin-related compound. Through overexpression or knockout of the gene, regulation and control of the potato tuber epidermis color can be achieved, a new way and gene resources are provided for potato variety improvement, and the gene has important theoretical value and application prospects.

The present invention provides "a conjugate of a chelating agent chelated with a radionuclide and a deglycosylated antibody, wherein the chelating agent site-specifically modifies the Fc region of the aforementioned antibody via a linker". The conjugate is improved in the risk of a decrease in the effect and the risk of side effects.

The application provides a preparation method of an aggregation-induced emission nanoparticle, which comprises the following steps: adopting triphenylamine as an electron donor (D), pyridine bromide as an electron acceptor (A), constructing a D-π-A structure, and synthesizing a nanoscale AIE photosensitizer nanoparticle by acting with an albumin stock solution; the nanoparticle synthesis method is easy to operate, has high yield and low cost, can simultaneously generate type I and type II reactive oxygen species (ROS), including ·OH (type I) and O2 (type II), and has good mitochondrial targeting function, and a Pearson correlation coefficient is as high as 0.97. 1 In addition, due to the modification of the terminal carboxyl group of TTPA, the nanoparticle has a pH response effect, can increase the accumulation or endocytosis of the nanoparticle in tumors, and can enhance the in-vivo imaging and treatment effect, and has potential clinical application value of intelligent response cancer diagnosis and treatment function.