2 results about "Pravastatin" patented technology

The invention belongs to the technical field of biological catalysis, and relates to a light-driven P450 catalytic system and application thereof in pravastatin synthesis. The system comprises a thylakoid membrane, Fdx, P450sca-2 and PC / Cyt C6, and is characterized in that the PC / Cyt C6 is connected with the Fdx; the thylakoid membrane takes H2O as an electron donor under an illumination condition, electrons are generated through a light system II, and the electrons are sequentially transferred to Fdx and are conveyed to P450sca-2 through interaction between proteins to catalyze an enzymatic reaction. According to the invention, light energy and / or water are / is used as an energy source and an electron source, expensive NAD (P) H is completely or partially replaced, and the production cost is greatly reduced. The system lays a certain foundation for constructing a P450 reaction system for photosynthesis and CO2 fixation in the future.

A method of treating a wound may include topically administering a statin composition including a statin selected from atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, simvastatin, or combination thereof. The statin composition may be administered in an ointment, powder, or liquid format. The method may also include topically administering one or more antimicrobial drugs and / or naltrexone.