3results about How to "Reduced bioavailability" patented technology

The application provides a kind of eye drop composition and its preparation method and application, belong to ophthalmic preparation technical field.The eye drop composition used in the application includes the following components: brimonidine tartrate, hyaluronic acid, collagen, trehalose, injection water;By compounding each component, a kind of eye drop capable of realizing brimonidine tartrate sustained release, prolonging the time of antihypertensive effect, and having the characteristics of reducing blinking discomfort, long-acting moisturizing, anti-inflammatory soothing, mild antiseptic, etc. is prepared;The eye drop of the application is helpful to glaucoma, high eye pressure, dry eye, postoperative inflammation or allergy, preservative-sensitive or preservative-allergic population, improves the quality of life, relieves the disease.

This invention provides a method and application for preparing bio-organic fertilizer through synergistic composting of biochar-containing biogas residue, belonging to the field of organic fertilizer preparation technology. The method includes: preparing biogas residue through anaerobic fermentation of livestock and poultry manure and crop straw; adding biochar and a compound microbial agent; conducting high-temperature aerobic composting; and obtaining bio-organic fertilizer through maturation and aging. The amount of biochar added is 5%-10% of the dry basis weight of the composting raw materials; the aerobic composting time is 35-45 days; and the high-temperature composting temperature is 55-65℃. The compound microbial agent includes *Bacillus steatophilus*, *Bacillus amyloliquefaciens*, and *Bacillus mucilaginosus*. The bio-organic fertilizer obtained by this invention can be used for crop soil improvement. This invention, through the synergistic effect of biogas residue, biochar, and compound microbial agent, effectively shortens the composting cycle, improves compost maturity, reduces nitrogen loss, passivates heavy metals, and significantly improves the quality of organic fertilizer.

This invention discloses the application and method of green manure return to the field in the remediation of cadmium pollution in red soil, belonging to the field of agricultural heavy metal pollution remediation technology. This method addresses the problems of high cost, potential secondary pollution, and difficulty in coordinating with agricultural production associated with chemical passivating agents in the remediation of cadmium-contaminated farmland in red soil. It utilizes a crop rotation system combining continuous planting and incorporation of milkvetch with rice planting and fertilization to simultaneously regulate and significantly increase soil microbial biomass carbon and amorphous iron oxide content, synergistically driving the transformation of soil cadmium from a highly active, weakly acidic extractable state to a more stable iron-manganese oxide-bound and organically bound state. This method achieves long-term, stable reduction of soil cadmium bioavailability without the need for additional chemical passivating agents, realizing a green, low-cost, and in-situ synergistic approach to cadmium pollution remediation and agricultural production, and has significant application value.