1837results about How to "Reduce concentration" patented technology

The present invention provides an in vitro system for compartmentalization of molecular or cellular libraries and provides methods for selection and isolation of desired molecules or cells from the libraries. The library includes a plurality of distinct molecules or cells encapsulated within a water-in-oil-in-water emulsion. The emulsion includes a continuous external aqueous phase and a discontinuous dispersion of water-in-oil droplets. The internal aqueous phase of a plurality of such droplets comprises a specific molecule or cell that is within the plurality of distinct molecules or cells of the library.

Embodiments of the present disclosure includes a portable pulse oximeter, such as a handheld pulse oximeter, that provides a user with intuitive key navigation for device operation, which reduces an amount of visual concentration needed to handle and operate the oximeter. In various embodiments, the portable pulse oximeter includes one or more of user input keys disposed along curve, an alignment edge providing guidance by feel of a user's digits to the input keys, raised convex keys also providing navigation by feel, a protective boot disposed around various portions of the oximeter housing to protect against impacts, a table-top stand, combinations of the same, or the like.

The present disclosure discloses a MOSFET and a method for manufacturing the same, wherein the MOSFET comprises: an SOI wafer which comprises a semiconductor substrate, a buried insulating layer, and a semiconductor layer, the buried insulating layer being on the semiconductor substrate, and the semiconductor layer being on the buried insulating layer; a gate stack on the semiconductor layer; a source region and a drain region, which are in the semiconductor layer and on opposite sides of the gate stack; and a channel region, which is in the semiconductor layer and sandwiched by the source region and the drain region, wherein the MOSFET further comprises a back gate, the back gate being located in the semiconductor substrate and having a first doped region in a lower portion of the back gate and a second doped region in an upper portion of the back gate. The MOSFET can adjust the threshold voltage by changing the doping type and doping concentration of the anti-doped region.

In accordance with the present invention, a dielectric barrier layer is presented. A barrier layer according to the present invention includes a densified amorphous dielectric layer deposited on a substrate by pulsed-DC, substrate biased physical vapor deposition, wherein the densified amorphous dielectric layer is a barrier layer. A method of forming a barrier layer according to the present inventions includes providing a substrate and depositing a highly densified, amorphous, dielectric material over the substrate in a pulsed-dc, biased, wide target physical vapor deposition process. Further, the process can include performing a soft-metal breath treatment on the substrate. Such barrier layers can be utilized as electrical layers, optical layers, immunological layers, or tribological layers.

Opaque flakes, such as pigment or bright flake used in paints and inks, have a selected shape and/or other indicia to provide a covert security feature to an object. In some embodiments the composition includes base pigment, and the opaque covert flakes match the visual characteristics of the base pigment. In another embodiment, opaque covert flakes are mixed in the carrier with base pigment at a concentration sufficient to avoid changing the appearance of the composition. In another embodiment, opaque covert flakes are mixed in a clear or tinted varnish base that can be applied over an existing security feature. Shaped opaque covert flakes are not readily detectable by causal observation, but in some embodiments are easily seen at 50× magnification. In manufacturing the flakes a sheet of embossed frames are provided having symbols or indicia within; upon removing a coating from the sheet the coating material tends to break along frame lines and the resulting flakes are substantially uniform in size.

The present invention relates to the use of carbon monoxide (CO) as a biomarker and therapeutic agent of heart, lung, liver, spleen, brain, skin and kidney diseases and other conditions and disease states including, for example, asthma, emphysema, bronchitis, adult respiratory distress syndrome, sepsis, cystic fibrosis, pneumonia, interstitial lung diseases, idiopathic pulmonary diseases, other lung diseases including primary pulmonary hypertension, secondary pulmonary hypertension, cancers, including lung, larynx and throat cancer, arthritis, wound healing, Parkinson's disease, Alzheimer's disease, peripheral vascular disease and pulmonary vascular thrombotic diseases such as pulmonary embolism. CO may be used to provide anti-inflammatory relief in patients suffering from oxidative stress and other conditions especially including sepsis and septic shock. In addition, carbon monoxide may be used as a biomarker or therapeutic agent for reducing respiratory distress in lung transplant patients and to reduce or inhibit oxidative stress and inflammation in transplant patients.

A process is disclosed for enhancing the production of light olefins using a catalyst with small pores. The catalyst comprises a molecular sieve having 10 membered rings with channels of limited length. The molecular sieve has a high silica to alumina ratio and has pores sized to limit production of aromatics in the cracking process.

A method for controlling an internal combustion engine to maintain a predetermined combustion efficiency, comprises: measuring the concentration of CO in an engine-out emission; determining whether the measured concentration of CO is above or below a target CO concentration for the engine under the operating conditions in use; and if the concentration of CO is above the target CO concentration, adjusting one or more engine and/or combustion parameters so as to reduce the concentration of CO in the engine-out emission, and if the concentration of CO is below the target CO concentration, adjusting one or more engine and/or combustion parameters so as to increase the concentration of CO in the engine-out emission; wherein the target CO concentration is determined on the basis of a correlation with indicators of combustion efficiency under known engine operating conditions. Exhaust gas recirculation (EGR) is one such engine and/or combustion parameter. A method for controlling an internal combustion engine to obtain an engine-out emission level of NOx within a predetermined concentration range is also described. The methods may be implemented by an engine control unit.

Carbon nanotube structures are disclosed in which nanotubes are disposed over a porous support such as a foam, felt, mesh, or membrane. Techniques of making these structures are also disclosed. In some of these techniques, a support is pretreated with a templated surfactant composition to assist with the formation of a nanotube layer.

A process and equipment for treating natural gas produced by a well that has recently been stimulated, and that contains an undesirably high concentration of the fracturing gas used to stimulate the well. The process involves treating the gas by membrane separation, and provides for control of treatment parameters to compensate for the changing concentration of fracturing gas in the produced gas, as well as changes in gas flow rate.

A light-emitting device (1) includes a substrate (10), a light-emitting element (12) that is mounted on the substrate (10) and includes a luminous region (12b) and a nonluminous region (12a), and a phosphor layer (13) that is formed to cover the light-emitting element (12). The thickness of the phosphor layer (13a) located on the nonluminous region (12a) is smaller than that of the phosphor layer (13b) located on the luminous region (12b). The light-emitting device (1) can suppress nonuniform luminescent color.

Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.

The invention belongs to the technical fields of environmental engineering and bioengineering and particularly relates to a sphingomonas strain and applications thereof in the aspects of shortcut nitrification-denitrification of nitrogen-containing industrial waste water and domestic sewage and treatment of a polluted water source. The sphingomonas strain is separated from a Taihu water in China,is a local strain and has high safety; and the strain can be grown in a basic medium, wherein in the basic medium, CO2 is used as a carbon source and energy or CO2 and an organism are used as a mixedcarbon source and energy, and ammonia nitrogen or nitrate nitrogen is used as a nitrogen source. The bacterium liquid, the dormancy cell and the immobilized strain of the sphingomonas can decompose ammonia nitrogen into nitrite nitrogen and simultaneously can decompose the ammonia nitrogen into nitrogen, can be used as denitrification microorganism for converting the ammonia nitrogen into the nitrite nitrogen and the nitrogen, thereby achieving the shortcut nitrification-denitrification. The strain can rapidly decompose the ammonia nitrogen and is suitable for treating the nitrogen-containingindustrial waste water and domestic sewage as well as polluted water source.

A medical composition for reducing the rate of new-onset diabetes caused by administration of a statin or for inhibiting an increase in blood glucose level by administration of a statin, the composition containing at least one ingredient selected from the group consisting of icosapentaenoic acid and pharmaceutically acceptable salts or esters thereof as an inactive ingredient.

A high performance liquid chromatography system employs a nebulizer with a flow restriction at the exit of its mixing chamber to produce finer droplets, and an adjustable impactor for increased control over droplet sizes. Downstream of the mixing chamber, the nebulizer can incorporate tubing that is permeable to the sample liquid, to promote aerosol drying through perevaporation. A condensation particle counter downstream of the nebulizer uses water as the working medium, and is adjustable to control threshold nucleation sizes and droplet growth rates. A particle size selector employing diffusion, electrostatic attraction or selection based on electrical mobility, is advantageously positioned between the nebulizer and the CPC.

Materials and Methods for immobilizing bioactive molecules, stem and other precursor cells, and other agents of therapeutic value in surgical sutures and other tissue scaffold devices are described herein. Broadly drawn to the integration and incorporation of bioactive materials into suture constructs, tissue scaffolds and medical devices, the present invention has particular utility in the development of novel systems that enable medical personnel performing surgical and other medical procedures to utilize and subsequently reintroduce bioactive materials extracted from a patient (or their allogenic equivalents) to a wound or target surgical site.

The present invention relates, at least in part, to the use of substituted tetracycline compounds for regulation of expression of nucleic acids operably linked to a tetracycline operator system. The invention pertains to compounds used in a regulatory system which utilizes components of the Tet repressor/operator/inducer system of prokaryotes to regulate gene expression in cells. Use of certain substituted tetracycline compounds, as featured in the methods of the invention, result in improved dose-response results when compared to those for e.g., tetracycline and doxycycline. Certain methods of the invention thus allow for enhanced control of the Tet repressor/operator/inducer system in regulating gene expression in cells.

An objective of the present invention is to provide methods for facilitating antigen-binding molecule-mediated antigen uptake into cells, methods for facilitating the reduction of antigen concentration in plasma, methods for increasing the number of antigens to which a single antigen-binding molecule can bind, methods for improving pharmacokinetics of antigen-binding molecules, antigen-binding molecules improved for facilitated antigen uptake into cells, antigen-binding molecules capable of facilitating the reduction of antigen concentration in plasma, antigen-binding molecules capable of repeatedly binding to antigens, antigen-binding molecules with improved pharmacokinetics, pharmaceutical compositions comprising such an antigen-binding molecule, and methods for producing those described above. The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human FcRn-binding activity at the plasma pH and a lower antigen-binding activity at the early endosomal pH than at the plasma pH; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies.

The invention discloses a plant extract deodorizer for removing harmful gases. The plant extract deodorizer comprises the following components in percentage by mass: 35-50% of plant extract, 1-2.5% of a stabilizer, and the balance of deionized water. The plant extract deodorizer for removing harmful gases can be used after being diluted by water, the amount of which is 1000 times than that of the plant extract deodorizer, can rapidly reduce the concentrations of harmful gases during the removal process of hydrogen sulfide, ammonia, methyl mercaptan and volatile organic gases, can eliminate the odor and peculiar smell brought by the harmful gases, and meanwhile, further has the effects of sterilization and bacteriostasis.

Solutions are prepared by dissolving N-(n-butyl)-thiophosphoric triamide (NBPT) in one or more N-substituted morpholines and mixtures thereof. The solutions may be used in urea fertilizers to reduce nitrogen volatilization, or to reduce the odor of animal waste or urine. Methods of preparing urea fertilizers and the resultant products are also described.

A method and chip for fusing droplets in a chip comprising (i) providing a first set of droplets which are partially or not stabilized by surfactant, (ii) providing a second set of droplets which are stabilized by surfactant, (iii) contacting each droplet of the first set with single or multiple droplets of the second set in a pairing module and (iv) fusing droplets of the first set with droplets of the second set through a droplet fusion module in which the droplets experience at least one acceleration and/or deceleration and/or reorientation and/or rearrangement in space and time.

This invention describes materials system and processing conditions for manufacturing magnetic circuit components such as induction coils and transformers that are non wire-wound, miniature in size and, have a low manufacturing cost. The materials system of this invention is comprised of: (1) Low Temperature Cofire Ceramic (LTCC) tapes or thick film pastes of ferromagnetic ceramics with a 20 to 750 range of magnetic permeability to form the magnetic core of the components, (2) Thick film buried silver conductor paste to form the planar induction coils on individual magnetic layers, (3) Thick film via-fill silver conductor paste to interconnect two or more of the planar induction coils through the thickness of the magnetic layers, (4) Thick film silver solderable top layer conductor paste compatible with the ferrite and, (5) Thick film dielectric paste with low magnetic permeability to redirect the magnetic flux for enhancing the magnetic coupling coefficient and to insulate the silver conductors for enhancing the dielectric breakdown voltage. The key characteristics of the materials system of this invention that facilitate manufacture of low cost non wire-wound, miniature magnetic circuit components are: (1) Mutual compatibility essential for either of the techniques, the cofire technique or the sequential technique, used for manufacturing multilayer hybrid microelectronic components, (2) Complementary thermo-physical properties such as shrinkage and thermal expansion coefficient essential for manufacturing flat multilayer magnetic components, (3) Magnetic components with magnetic coupling coefficients greater than 0.95 under optimal processing conditions and, (4) Magnetic components with dielectric breakdown voltage greater than 500V/mil under optimal processing conditions.

An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction.

A perpendicular magnetic recording medium for enabling high density recording is disclosed. The perpendicular magnetic recording medium includes a substrate on which a soft magnetic underlayer, a seed layer made of a non-crystalline material, an underlayer made of Ru or an Ru alloy including Ru as a main component, and a recording layer including a first magnetic layer and a second magnetic layer. The first and second magnetic layers include a plurality of magnetic grains having easy magnetization axes in a substantially perpendicular direction with respect to the substrate surface, and first and second nonmagnetic non-soluble phases segregating the magnetic grains of the first and second magnetic layers, respectively. The first magnetic layer includes the first non-soluble phase at a first atomic concentration that is higher than a second atomic concentration of the second non-soluble phase in the second magnetic layer.

Strains of lactic acid bacteria selected for their capability of increasing the BSH-activity and consequently lowering serum LDL-cholesterol, and simultaneously decreasing the pro-inflammatory cytokine TNF-α levels, for prophylaxis and/or treatment of atherosclerosis and other cardiovascular diseases, a method of selecting such strains, and products containing such strains.

The present invention discloses a process for producing nickel nanoparticles. The process involves heating a nickel precursor generated in situ in the presence of a carrier gas under conditions effective to decompose the nickel precursor and produce nickel nanoparticles.

A hydrodynamic device for removing sediment and other materials from storm water runoff is provided. An exemplary embodiment of this device includes: a first substantially cylindrical chamber a second substantially cylindrical chamber concentrically disposed within the upper portion of the first chamber, a first baffle concentrically disposed within the second chamber, and a second baffle disposed within the lower portion of the first chamber. A water inlet is attached to or formed integrally with the second chamber; a water outlet is attached to or formed integrally with the first chamber; and an optional bypass outlet is attached to or formed integrally with the first chamber.

The invention relates to saline-alkali soil paddy rice special-purpose carbon-based organic fertilizer. The saline-alkali soil paddy rice special-purpose carbon-based organic fertilizer has a low cost and high fertilizer efficiency, is economic and environmentally friendly, improves a soil water binding capacity and permeability, and has functions of keeping fertility, slowly releasing fertilizer and reducing paddy rice salinization. The saline-alkali soil paddy rice special-purpose carbon-based organic fertilizer comprises biomass charcoal, chicken manure, pyroligneous liquor, fermented soybean meal and potassium humate. The biomass charcoal is prepared by thermal cracking charring of biomass raw materials under anoxic conditions. The saline-alkali soil paddy rice special-purpose carbon-based organic fertilizer can be used for paddy rice plantation, can improve a saline-alkali soil environment and can improve an organic paddy rice yield.

In one embodiment, a solid solution material comprises, based upon 100 mole %: about 30 mol% about 95 mol % zirconium, about 0.5 mol % to about 50 mole % cerium, up to about 20 mole % of a stabilizer selected from the group consisting of yttrium, rare earths, and combinations comprising at least one of the stabilizers, and about 0.01 to about 25 mole % of a metal selected from the group consisting of indium, tin, and mixtures comprising at least one of the foregoing metals.

The invention provides novel compositions of water-insoluble corticosteroid drug in combination with antimicrobial agents and very low concentrations of polymers and surfactants for topical, otic and ophthalmic treatment. The invention provides stable aqueous suspension where the ingredients remain in such a state so as to allow for immediate re-suspension, when desired, even after extended periods of settling. The invention provides also a method for treating inflammation with low systemic absorption and side-effects of the corticosteroid.