183results about How to "Emulsion stabilization" patented technology

The present invention provides an in vitro system for compartmentalization of molecular or cellular libraries and provides methods for selection and isolation of desired molecules or cells from the libraries. The library includes a plurality of distinct molecules or cells encapsulated within a water-in-oil-in-water emulsion. The emulsion includes a continuous external aqueous phase and a discontinuous dispersion of water-in-oil droplets. The internal aqueous phase of a plurality of such droplets comprises a specific molecule or cell that is within the plurality of distinct molecules or cells of the library.

This invention generally relates to cationic oil-in-water emulsions that contain high concentrations of cationic lipids and have a defined oil:lipid ratio. The cationic lipid can interact with the negatively charged molecule thereby anchoring the molecule to the emulsion particles. The cationic emulsions described herein are useful for delivering negatively charged molecules, such as nucleic acid molecules to cells, and for formulating nucleic acid-based vaccines.

A composition comprising purified water using ozonation, ionization, or distillation or any combination thereof wherein alcohol may be substituted for, or combined with water at least one emollient including but not limited to chitosan, and aloe vera gel, individually or in any combination; an oil component with spf boosting agents including but not limited to; ethyl macadamiate, non-toxic silicone oil and essential oils, butter milk, waxes impregnated with inorganic sun-block or sunscreen agent and organic / inorganic micronized particles, wood powder and bentonite clay, keratin, either individually or in any combination; at least one inorganic sun-block or sunscreen agent including any metal oxide, glass microsphere, silica and silica compound, and optionally metal oxide pigments with particles that are micronized, submicronized, nanoparticle sized, or otherwise individually or in any combination that can be homogenized in either a water phase, a water-aloe phase, an oil phase or any phase of said composition; at least one emulsifier wherein said emulsifier includes but is not limited to a phospholipid and / or liposome or an aloe vera gel or an ester of coconut oil individually or in any combination, for emulsifying the water, water-aloe, or oil phase in combination with an homogenizer; where any of components are preferably mixed with an homogenizer and where an appropriate thickening agent including but not limited to xanthan gum, carageenan, either individually or in any combination is added as required.

The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.

An invert emulsion drilling fluid, and a method for the use thereof in drilling wellbores, with good rheological properties at high temperatures and pressures. One embodiment of the drilling fluids are free of organophilic clays and lignites, free of calcium chloride, and comprise an alcohol in the internal phase, a quaternary ammonium emulsifier, and argillaceous solids. In one embodiment, the alcohol is a glycerol, a polyglycerol, or a mixture thereof. In one embodiment, the base oil for the emulsion is a paraffin and / or mineral oil. The drilling fluids provide good lubricity and high rates of penetration.

An emulsion of α-tocopherol, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans via various routes is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated α-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of α-tocopherol.

The present invention relates to polyglycerol partial esers of polyhydroxystearic acid and polyfunctional carboxylic acids which are obtainable by esterification of a polyglycerol mixture with polyhydroxystearic acid where N=1 to 10, preferably 2 to 8, in particular 3 to 5 units and dimer fatty acids which have been obtained by catalytic dimerization of unsaturated fatty acids having 12 to 22 C atoms and have an average functionality of 2 to 3, and / or with aliphatic, linear or branched dicarboxylic acids having a chain length of 2 to 16 C atoms and additionally saturated or unsaturated, linear or branched fatty acids having 6 to 22 C atoms, preferably 12 to 18 C atoms, the degree of esterification of the polyglycerol mixture being between 20 and 75%, preferably 40 to 70%.

The present invention relates to a water-in-oil-in-water multiple emulsion system and a method for preparation thereof, characterized by hydrodynamically stabilizing the multiple emulsion system by using hydrodynamic dual stabilization (HDS) technology. The HDS technology hydrophobizes water molecules in the internal aqueous phase by using a hydrogen bonding inhibitor and by improving the aggregating force between water molecules in the internal aqueous phase by using a water molecule aggregating agent.

A method of making an emulsion of tocopherol incorporating a co-solvent and, stabilized by biocompatible surfactants, as a vehicle or carrier for therapeutic drugs, which is substantially ethanol free and which can be administered to animals or humans by various routes, is disclosed. Also included in the emulsion is PEGylated vitamin E. PEGylated α-tocopherol includes polyethylene glycol subunits attached by a succinic acid diester at the ring hydroxyl of vitamin E and serves as a primary surfactant, stabilizer and a secondary solvent in emulsions of α-tocopherol.

A gravel packing fluid and method for gravel packing a wellbore using a gravel packing fluid comprising an invert emulsion comprising oil as an external phase, clear brine as an internal phase, and a quantity of emulsifier effective to produce a stable invert emulsion, the external phase of the gravel packing fluid further comprising gravel wetting agent.

The present technology relates to liquid compositions for use in a personal vaporizer. More particularly, the present technology relates to liquid compositions for forming stable emulsions of oil-soluble compounds and resins, and to methods of administering vaporized oil-soluble compounds and resins to a subject by inhalation.

The invention provides protein adhesives and methods of making and using such adhesives. The protein adhesives contain ground plant meal or an isolated polypeptide composition obtained from plant biomass.

This invention provides emulsions and adhesives comprising proteins that can be isolated from a variety of sources including renewable plant biomass, and methods of making and using such emulsions and adhesives.

A novel organopolysiloxane having a hydrophilic group, which can be produced easily and is not susceptible to two-phase separation, sedimentation of unreacted materials or the like after production, while being chemically stable and excellently practical, is disclosed. A method for producing the organopolysiloxane; and uses of the organopolysiloxane are also disclosed. The organopolysiloxane is a co-modified organopolysiloxane which has a group having a siloxane dendron structure and a hydrophilic group.

The invention relates to a composition for topical application in the form of an O / W emulsion containing at least one wax and at least one particular amphiphilic polymer, and to the use of the composition, in particular for caring for, protecting and / or making up body or facial skin, the eyelashes and / or the lips, and / or for haircare.

The present invention discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; (2) initiating polymerization of said monomer within the aqueous polymerization medium to produce a latex of an unsaturated polymer; (3) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer. The present invention further discloses a process for synthesizing a hydrogenated polymer that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than about 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than about 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier; (4) initiating free radical polymerization to produce a latex of an unsaturated polymer; and (5) treating the latex of the unsaturated polymer with (a) an oxidant selected from the group consisting of oxygen, air and hydroperoxides; (b) a reducing agent selected from the group consisting of hydrazine and hydrates of hydrazine; and (c) a metal ion activator to produce the hydrogenated polymer.

The present invention relates to a composition in the form of an emulsion of the oil-in-water type formed of oily globules which are each provided with a lamellar liquid crystal coating and which are dispersed in an aqueous phase, wherein it has a pH ranging from 3 to 5.5 and in that it contains at least one lipophilic surface-active agent with an HLB ranging from 2 to 5, at least one hydrophilic surface-active agent with an HLB ranging from 8 to 12 and at least one amphiphilic compound of ionic nature at a pH ranging from 3 to 5.5.

A novel organopolysiloxane having a hydrophilic group, which can be produced easily and is not susceptible to two-phase separation, sedimentation of unreacted materials or the like after production, while being chemically stable and excellently practical, is disclosed. A method for producing the organopolysiloxane; and uses of the organopolysiloxane are also disclosed. The organopolysiloxane is a co-modified organopolysiloxane which has a group having a siloxane dendron structure and a hydrophilic group.

An apparatus, system and method for emulsifying oil and water, such as for emulsifying a sizing agent for use in treating paper or paperboard, introduces a continuous phase under pressure through a continuous phase nozzle of a venturi apparatus and into a mixing section. A dispersed phase is introduced optionally under pressure into the mixing section of the venturi apparatus. The emulsion formed in the mixing section is directed through a mixed phase nozzle and out of the venturi apparatus. The mixed phase nozzle diameter of the venturi apparatus is larger than the continuous phase nozzle diameter at a ratio of greater than 1:1 and less than 4:1.

Described herein are fungicidal compositions in the form of emulsifiable concentrates that comprise a first fungicidal compound, optionally, at least one additional fungicidal compound, two or more surfactants and a water immiscible organic solvent comprised of a mixture of organic compounds including an acetate ester, an N,N-dialkylcarboxamide and at least one of a ketone and an alcohol. The compositions are homogeneous, stable upon storage, and upon dilution in water form stable emulsions that can be sprayed onto plants to control important fungal diseases.

The present invention discloses an emulsion polymerization process that comprises: (1) preparing an aqueous polymerization medium which is comprised of (a) at least one monomer, (b) a polymerization control agent, and an emulsifier, wherein the emulsifier is prepared in-situ within the aqueous polymerization medium; and (2) initiating polymerization of said monomer within the aqueous polymerization medium. The subject invention more specifically reveals an emulsion polymerization process that comprises: (1) preparing a monomer solution which is comprised of (a) at least one monomer, (b) a conjugate acid of a surfactant with a pKa of less than 14, and (c) a controlled free radical polymerization agent; (2) preparing an aqueous medium which is comprised of (a) water, and (b) a conjugate base of a weak acid wherein the pKb of the base is less than 14; and (3) mixing the monomer solution with the aqueous medium under conditions that result in the in-situ formation of an emulsifier, and (4) initiating free radical polymerization.

The present invention provides edible aqueous oil-in-water emulsions comprising 15-70% wt oil having a saturated fatty acid content of at least 20% wt and at least 10% wt of said oil being solid at 37° C., 0.1-5% wt emulsifier which is a protein and 25-84.9% wt water. The oil preferably comprises palm oil and the emulsifier preferably comprises partially denatured egg white. The emulsions provide good satiety benefits and do not adversely affect the taste of products into which they are incorporated. Furthermore the emulsions are very stable which has benefits also for the food products and beverages into which they are incorporated. Also provided are food and beverage products comprising the emulsion of the invention.

Described herein are fungicidal compositions in the form of an emulsifiable concentrates that include a first fungicidal compound, optionally, at least one additional fungicidal compound, two or more surfactants and a water immiscible organic solvent comprised of a mixture of organic compounds including at least one acetate ester and at least one N,N-dialkylcarboxamide. The compositions are homogeneous, stable upon storage, and upon dilution in water form stable emulsions that can be sprayed onto plants to control important fungal diseases.

A stable FC emulsion is described. The FC emulsion of the present invention comprises a continuous FC immiscible hydrophilic liquid phase and a dispersed phase comprising FC suspended as droplets within the continuous phase. The emulsion further comprises an emulsifying agent and a stabilizing agent. The stabilizing agent of the present invention reduces the ability of the FC droplets to move within the continuous phase. The present invention also provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent. The method comprises mixing an FC immiscible hydrophilic liquid and an emulsifying agent to form a first mixture; mixing a stabilizing agent with the first mixture to form a second mixture; and mixing FC with the second mixture to form a third mixture to disperse droplets of FC in the FC immiscible hydrophilic liquid and to form the FC emulsion, wherein the stabilizing agent reduces ability of the droplets to move within a continuous phase of the FC emulsion.

A polymerization process to copolymerize hydrophobic ethylenically unsaturated C4-C30. J olefins with polar monomers such as acrylates is described. The process utilizes an acid source to modify / catalyze the reactivity of the polar monomer and / or radically activated repeat unit from the polar monomer to promote incorporation of the ethylenically unsaturated olefin. The copolymer shows excellent adhesion to a variety of polymeric and / or polar substrates such as polyolefins, acrylatc coatings, wood, etc.

Described herein are fungicidal compositions in the form of an emulsifiable concentrates that include a first fungicidal compound, optionally, at least one additional fungicidal compound, two or more surfactants and a water immiscible organic solvent comprised of a mixture of organic compounds including at least one acetate ester, at least one N,N-dialkylcarboxamide and at least one of a ketone and an alcohol, and methods of use of such compositions to control important fungal diseases of plants.

The present invention relates to a composition for treating acne comprising an anti-microbial peptide made from the amino acids phenylalanine, alanine, leucine and lysine with said peptide admixed with salicylic acid and / or salicylate salts in a cosmetic delivery vehicle containing a rehydrating polymer. The invention further relates to a method for treating acne by topically administering one of the compositions in an amount therapeutically effective to reduce the redness and blemishes associated with acne.

The invention provides an emulsification technique which permits the formation of functional oil / water or functional granules / water emulsion systems excellent in thermal stability and long-term stability and which can attain the emulsification independent of required HLB of the functional oils, and the dispersion independent of surface properties of the functional granules. In the technique is used an emulsifying dispersant comprising, as the main component, vesicles formed from an amphiphilic substance capable of self-assembly or an emulsifying dispersant comprising single particles of a biopolymer as the main component. The particles made from amphiphilic substances capable of self-assembly are used. The amphiphilic substances are selected from among polyoxyethylene-hydrogenated castor oil derivatives represented by the general formula (1) wherein the average number of added ethylene oxide molecule is 5 to 15, dialkyldimethyl-ammonium halides wherein the chain length of the alkyl or alkenyl is 8 to 22, and phospholipids or phospholipid derivatives. According to the invention a three-phase structure composed of an aqueous phase, an emulsifying dispersant phase and an oil phase is formed on the surface of an emulsion to give an emulsion (such as emulsion fuel) excellent in thermal stability and long-term stability.

The invention provides protein adhesives and methods of making and using such adhesives. The protein adhesives contain ground plant meal or an isolated polypeptide composition obtained from plant biomass.