65 results about "POLYHYDROXYSTEARIC ACID" patented technology

The invention provides a compound nystatin ointment and a preparation method thereof, and relates to the technical field of medicine preparation, the compound nystatin ointment comprises active ingredients of nystatin, neomycin sulfate, triamcinolone acetonide and permethrin, and the formula comprises liquid paraffin, white vaseline, wool fat, hexadecanol, PEG-30 dipolyhydroxystearate and glyceryl monoisostearate. According to the compound nystatin ointment preparation prescription process disclosed by the invention, the phenomenon of ointment matrix layering in the use process of commercially available products is mainly solved. According to a pharmaceutical research test, the stability of the compound nystatin ointment is superior to that of a commercially available original development agent, the ointment body character and the stability of active ingredients can be kept under the conditions of high temperature, high humidity, low temperature, freeze thawing and illumination, the maximum single impurity content and the total impurity content in the product are not obviously increased, and the quality is controllable. And meanwhile, an in-vitro transdermal test (IVPT) accidentally finds that the retention amount of related active ingredients is higher than that of the original development agent, and the drug effect is obviously improved. Through clinical test research, the compound nystatin ointment disclosed by the invention can be used for effectively treating external otitis caused by bacteria sensitive to neomycin, fungi sensitive to nystatin and ear mites sensitive to permethrin of dogs and cats.

The invention discloses an oil-in-water type sunscreen product and a preparation method thereof, and belongs to the technical field of cosmetics. The oil-in-water type sunscreen product is prepared from the following components in parts by weight: 0.01 to 1 part of thickening agent and 0.01 to 5 parts of dispersion stabilizer, wherein the thickening agent comprises carbomer, an acrylic acid (ester) / C10-30 alkanol acrylate cross-linked polymer and a hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer; the dispersion stabilizer is prepared from disteardimonium hectorite and polyhydroxystearic acid. The oil-in-water type sunscreen product has the advantages of good sunscreen effect, good stability, small skin irritation, fresh and cool skin feeling and good conformity. The preparation method comprises the step of mixing the preparation raw materials of the oil-in-water type sunscreen product according to a preset ratio, and the method is simple, easy to operate and suitable for industrial production.

The invention belongs to the technical field of dispersing agents, and particularly relates to a dispersing agent based on caprolactone and polyethyleneimine and a preparation method of the dispersing agent. The preparation method comprises the following steps: (1) adding xylene into a dry reaction kettle, adding a caprolactone monomer and polyhydroxystearic acid, and uniformly stirring; (2) slowly adding an organic tin catalyst into the reaction kettle, adding an antioxidant BHT (butylated hydroxytoluene), heating the reaction system to 120-140 DEG C, and starting stirring to obtain a modified polycaprolactone system; and (3) adding polyethyleneimine into the modified polycaprolactone system, heating to 160-180 DEG C, and continuously reacting for 1-2 hours to obtain the dispersant based on caprolactone and polyethyleneimine. The dispersing agent disclosed by the invention can show a good dispersing effect in a water-based system and an oil-based system, has good system compatibility, and is suitable for various complex application environments, so that the application range of the dispersing agent is widened.

The invention discloses a cosmetic composition and a preparation method and application thereof, the cosmetic composition comprises functional powder, polyol, water, an emollient, a thickening agent, a surfactant and an emulsifier, the thickening agent comprises xanthan gum, sodium polyacrylate and a sodium acrylate / sodium acryloyldimethyl taurate copolymer, and the emulsifier comprises sodium polyacrylate and sodium acryloyldimethyl taurate. The surfactant is prepared from sodium stearoyl glutamate and potassium cetyl phosphate, and the emulsifier is prepared from polyglycerol-2 dipolyhydroxystearate; the cosmetic composition disclosed by the invention can realize phase inversion in a use process (the cosmetic composition is initially in an oil-in-water type and can be converted into a water-in-oil type in a smearing process), has relatively good stability and a relatively good water-resistant effect, and can simultaneously meet a refreshing skin feeling and a makeup-holding and sweat-preventing function.

The invention provides a composition with full-wave-band invisible light-blocking and sun-screening effects and application thereof. The composition comprises zinc oxide, lactobacillus / soybean milk fermentation product filtrate, a sun-screening auxiliary agent and a dispersing agent, the sun-screening auxiliary agent comprises silica, sodium calcium aluminum silicate, a vinyl polydimethylsiloxane / polymethylsiloxane silsesquioxane cross-linked polymer, polymethyl methacrylate, a silane coupling agent, a silane coupling agent and a solvent. The silicone rubber is any one or a combination of at least two of diphenyl polydimethylsiloxane / vinyl diphenyl polydimethylsiloxane / silsesquioxane cross-linked polymer or polymethyl silsesquioxane; the dispersing agent is prepared from any one or a combination of at least two of polyhydroxystearic acid, cholesteryl hydroxystearate, dimeric pentaerythritol pentaisostearate, ethylhexyl hydroxystearate or dimeric pentaerythritol tri-polyhydroxystearate. The composition can increase the full-wave-band sunscreen performance, avoid skin sunburn, sunburn and sunburn red, and enhance the skin barrier.

Disclosed is a W / O / W type emulsified composition exhibiting excellent stability. This W / O / W type emulsified composition comprises: an inner water phase; an oil phase in which the inner water phase is dispersed; and an outer water phase in which the oil phase is dispersed. The inner water phase contains an osmotic pressure regulator. The osmotic pressure regulator generates the osmotic pressure between the inner water phase and the outer water phase. Contained as a surfactant for emulsifying the inner aqueous phase in the oil phase is at least one selected from the group consisting of polyethylene glycol dipolyhydroxystearate and polyglycerol fatty acid esters having an average degree of polymerization of glycerol of 2-9. The osmotic pressure regulator contains at least one selected from the group consisting of citric acid, citrates, and sulfates.

The present invention relates to a cosmetic preparation comprising at least one mineral sunscreen filter, polyglyceryl-4 diisostearate / polyhydroxystearate / sebacate, polyhydroxystearic acid, isostearic acid, polyglyceryl-2 oleate and polyglyceryl-2 stearate; and the use of the preparation for protection against sunlight.

A metal oxide dispersion composition with excellent stability over time, excellent non-stickiness, and good usability is provided. This metal oxide dispersion composition contains the following components (A) to (C): (A) polyhydroxystearic acid, (B) silicone-treated metal oxide, and (C) glyceryl oleate, wherein the metal oxide of component (B) is a metal oxide other than titanium dioxide.

The present application relates to a kind of cacao seed fat and sea buckthorn fruit oil compounded sunscreen synergistic composition and its preparation method, belong to cosmetic technical field.The sunscreen synergistic composition disclosed in the present application includes the following raw materials: cacao seed fat, sea buckthorn fruit oil, propolis extract, phytosteryl oleate, raspberry seed oil, farnesol, gynura extract, polyhydroxy stearic acid, wherein the mass ratio of sea buckthorn fruit oil in the sunscreen synergistic composition is 10-13.5%;The extraction of sea buckthorn fruit oil adopts the process of pulse electric field treatment-subsection high pressure pretreatment-supercritical extraction, improves the yield of sea buckthorn fruit oil without destroying active ingredients, and does not introduce new substances to retain its purity;Through the interaction of the above components, the sunscreen and soothing effect of the composition is enhanced from the triple action of defense, strengthening and repair.

The invention relates to the technical field of cosmetics, and discloses an oil wax composition of a high-water-holding complex stably-loaded water active matter and a preparation method, the oil wax composition of the high-water-holding complex stably-loaded water active matter comprises a high-water-holding complex, an oil wax phase and a water-based active matter phase, the high water holding complex comprises polyglycerol-2 dipolyhydroxystearate, polyglycerol-10 eicosanoic acid ester / tetradecanedioic acid ester, polyglycerol-3 rice bran acid ester, 1%-6% of polyglycerol-6 polyricinoleate, bis-behenyl alcohol / isostearyl alcohol / phytosterol dimer linoleate, dipentaerythritol hexahydroxy stearate / hexastearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate, polyglyceryl tristearate and polyglyceryl tristearate. According to the lip care composition, a water-based active matter phase can be stably borne in a high-load mode, water-based activity is effectively conveyed to the lip surface in the using process, and therefore the moisturizing, repairing and functional care effects of the lip are remarkably improved.

To provide a water-in-oil cosmetic that offers both excellent usability as a cosmetic product and high stability. [Solution] A water-in-oil cosmetic composition containing 50% by mass or more of water, comprising the following components (A) to (C): (A) dipolyhydroxy fatty acid polyalkylene glycol, (B) sesquiisostearate sorbitan, and (C) oil thickener. Preferably, component (A) is polyethylene glycol dipolyhydroxystearate, component (B) is sorbitan sesquiisostearate, and component (C) is dextrin palmitate.

To provide a water-in-oil type emulsion cosmetic composition which has high dispersibility of metal oxide particles in a liquid oil, is less likely to cause caking, and has strong high-temperature stability even when no silicone oil is used or only a small amount of a silicone oil is used.A water-in-oil type emulsion cosmetic composition includes the following components: surface-treated zinc oxide particles, surface-treated titanium oxide particles, polyhydroxystearic acid, polyricinoleic acid polyglycerol ester, an organically modified clay mineral, an aqueous component, and a liquid oil, wherein a content of the polyhydroxystearic acid is less than 1.0 mass %, and a content of the aqueous component is less than 15 mass %.

The present invention discloses a coating for a drug-eluting stent, which comprises a phase A and a phase B; the raw materials of the phase A include: carboxymethyl chitosan, ginkgo flavonoids, resveratrol, vascular endothelial growth factor, rapamycin, PEG-30 dimeric hydroxystearate, glycerol, silicone oil, and an aqueous acetic acid solution with a mass fraction of 0.1-0.5%; the raw materials of the phase B include: polylactic acid, polyethylene glycol, and dichloromethane. The coating for a drug-eluting stent proposed by the present invention not only has a good coating effect on drugs, but also can realize the continuous and slow release of the coated drugs from the surface of the stent, which not only restricts the proliferation of local vascular intimal cells, but also reduces the proliferation-promoting factors such as inflammatory reactions, thereby further enhancing the restriction effect on restenosis and improving the clinical practicability.

This application relates to a fluid water-in-oil emulsion comprising: A) at least one polyester, which is a reaction product of the following components (i), (ii) and (iii): (i) at least one polyglycerol-3; (ii) at least one dimer acid; and (iii) at least one fatty monocarboxylic acid having 8 to 30 carbon atoms, wherein the reacting components (i), (ii) and (iii) are in a molar ratio of 1 mole of polyglycerol-3, 0.5 to 1 mole of dimer acid, and 0.1 to less than 2.0 moles of fatty monocarboxylic acid; B) at least one continuous oil phase comprising: 1) at least one volatile hydrocarbon oil; and 2) optionally at least one non-volatile oil; and C) at least one aqueous phase dispersed in the oil phase, wherein the liquid component of the aqueous phase accounts for at least 50% by weight of the total weight of the composition; and D) At least one nonionic surfactant with an HLB of less than 8.0, the chemical structure of which is generated by the reaction of at least one polyhydroxystearic acid and / or at least one polyricinoleic acid with a polyol containing at least two alcohol functional groups; the weight ratio of nonionic surfactant D) to polyester A) is greater than or equal to 0.9 and preferably greater than or equal to 1.0.

The invention provides a coated paper for packaging and a preparation method thereof. The coated paper comprises the following raw material components: 20-25 parts of modified corn starch citrate, 75-80 parts of alginic acid, 20-25 parts of polypropylene carbonate, 20-25 parts of polylactic acid, 1-3 parts of glycerol, 1-3 parts of polyhydroxystearic acid and 2-2.5 parts of carboxymethyl cellulose. The preparation method of the modified corn starch citrate comprises the following steps: in a reaction kettle, preparing a citric acid solution with a mass percentage of 0.8-1.2% by using distilled water, and heating the solution to 35-38 DEG C; starting stirring; adding corn starch to the citric acid solution while stirring, and reacting for 2.5-3 hours; then, adjusting the pH value of the solution in the reaction kettle to be alkaline with sodium hydroxide, cooling the solution to 26-28 DEG C, adding octenyl succinic anhydride and sodium alginate, and continuing stirring and reacting for 30-50 minutes; after the reaction, standing and filtering; drying and grinding the filtered solid to 80-100 meshes. The coated paper prepared by the invention is environmentally friendly, safe and easily degradable.

The present invention provides an oil-in-water emulsion cosmetic having excellent stability against temperature changes. An oil-in-water emulsion cosmetic solving the problem of the present invention is characterized by containing the following components (A) to (E): (A) one or two or more selected from the group consisting of a copolymer of (meth)acrylic acid or an alkyl (meth)acrylate and a polyoxyethylene monoalkyl ether (meth)acrylate, and a copolymer or salt thereof containing acryloyldimethyltaurine as a structural unit, (B) a branched polysaccharide, (C) one or two or more selected from the group consisting of ester oil, hydrocarbon oil, and higher alcohol, which is liquid at 25°C, (D) a hydrophobic-treated metal oxide of 7 mass% or more and 25 mass% or less, and (E) one or two or more selected from the group consisting of an acrylic acid-silicone graft copolymer, polyhydroxystearic acid, and a polyglycerin alkyl co-modified silicone.

Provided is an oil-in-water emulsified cosmetic composition having a characteristic fresh feel during use while exhibiting excellent emulsified stability and high covering power. The oil-in-water emulsified cosmetic composition comprises the following components (a) to (d): (a) pigment particles with a mean particle size of 200 to 500 nm and hydrophobically treated on the surface, (b) a water-soluble alkyl-substituted polysaccharide derivative, (c) polyhydroxystearic acid, and (d) an oil containing a polar oil, wherein the pigment particles are dispersed in the oil, the content of the pigment particles is 8.0 mass% to 15 mass%, and the content of nonionic surfactants with an HLB value of 10 or greater is 1.0 mass% or lower.

The present invention provides a novel emulsified cosmetic that maintains the properties of W / O / W type emulsified cosmetics, improves their stability over time, and allows for the incorporation of polar oily components without impairing the system's stability. [Solution] An O / W / O / W type emulsified cosmetic is provided, in which an O / W / O type emulsion is dispersed in an aqueous phase, comprising an O / W type emulsion in which an inner oil phase containing a polar component (A) is dispersed in an aqueous phase, and an oil phase containing dipentaerythrityl tripolyhydroxystearate (B) and not containing the polar component (A) is dispersed in an aqueous phase, wherein the O / W / O type emulsion is dispersed in an aqueous phase containing a water-soluble polymer. Specific examples of the polar component (A) include oil-soluble vitamins, carotenoids, essential oils, and oil-soluble ultraviolet absorbers, and specific examples of the water-soluble polymer include carbomers, alkyl-modified carboxyvinyl polymers, 2-acrylamido-2-methylpropanesulfonic acid-based water-soluble polymers, hydrophobic-modified polyether urethanes, and hydrophobic-modified alkylcelluloses.

The application discloses a long-acting makeup holding foundation liquid, which comprises water, titanium dioxide, hydrogenated polydecene, isododecane, isohexadecane, dimethicone, caprylic acid / capric acid triglyceride, dipropylene glycol, silica, polyglyceryl-2 dipolyhydroxystearate, synthetic fluorphlogopite, polymethylsilsesquioxane, a film forming agent, magnesium sulfate, cetyl PEG / PPG-10 / 1 dimethicone, lithium montmorillonite, triethoxysilane, ethanol, dimethicone / vinyl dimethicone crosspolymer, alumina, dimethiconol, collagen, natural extract, a colorant, a moisturizing agent and trace additives. The long-acting makeup holding foundation liquid has reliable water supplementing and moisturizing and oil control effects, can selectively absorb and control oil, has reliable skin friendliness, can reliably protect makeup of oily skin, and avoids the problem of makeup removal caused by facial oil secretion.

The invention relates to the field of daily chemicals, and provides a silicon-free hair care composition added with a water-in-oil emulsifier, which comprises a cationic conditioner, the water-in-oil emulsifier, an oil-in-water emulsifying thickener, a grease conditioner, a humectant and pure water, the water-in-oil emulsifier is prepared from PEG-30 (Polyethylene Glycol) dipolyhydroxy stearate; the oil-in-water emulsifying thickener comprises one or more of hexadecanol, octadecanol and cetostearyl alcohol. According to the silicon-free hair care composition disclosed by the invention, the water-in-oil emulsifier is added into an oil-in-water system to form a similar water-in-oil-in-water composite system, and compared with an oil-in-water system of a common single emulsifier, the silicon-free hair care composition disclosed by the invention can emulsify grease into fine and uniform micro-droplets, and can better permeate hair and nourish and repair damaged hair without greasy and heavy hair.

The invention relates to the field of cosmetics, and particularly discloses a polyglycerol fatty acid ester O / W / O type multiple emulsion as well as a preparation method and application thereof. The polyglycerol fatty acid ester O / W / O multiple emulsion provided by the invention is prepared from the following components: propylene glycol serving as a stabilizer, pullulan serving as a thickener, polyglycerol-10 laurate serving as a water-soluble emulsifier, polyglycerol-2 dipolyhydroxystearate serving as an oil-soluble emulsifier and polyglycerol-3 diisostearate serving as an oil-soluble emulsifier. According to the multi-emulsion disclosed by the invention, the polyglycerol fatty acid ester emulsifier with a natural source is adopted, so that the multi-emulsion has environmental degradability and safety to a human body. The product prepared by the method disclosed by the invention has the characteristics of safety, environmental friendliness, skin friendliness, simplified production process and the like.

This O / W / O / W emulsion cosmetic preparation is obtained by dispersing, in an external aqueous phase containing a water-soluble polymer, an O / W / O emulsion that includes: as a dispersion phase, an O / W emulsion obtained by dispersing an internal oil phase containing a polar component (A) in an aqueous phase; and, as a continuous phase, an oil phase containing dipentaerythrityl tri-polyhydroxystearate (B) but not containing the polar component (A). Specific examples of the polar component (A) include oil-soluble vitamins, carotenoids, essential oils, and oil-soluble ultraviolet absorbers. Specific examples of the water-soluble polymer include carbomers, alkyl-modified carboxyvinyl polymers, 2-acrylamido-2-methylpropane sulfonic acid-based water-soluble polymers, hydrophobically modified polyether urethanes, and hydrophobically modified alkyl celluloses.

[Problem] An objective of the present invention is to provide an oil-in-water emulsion cosmetic having a watery and well-spreading texture in use and having excellent covering performance.[Solution] The oil-in-water emulsion cosmetic of the present invention contains (A) an aqueous component selected from monohydric alcohols and dihydric alcohols; (B) a polyoxyalkylene-modified silicone; (C) an oil; (D) a powder having a hydrophobized surface; and (E) a dispersant that is one or more compounds selected from (E-1) a polyglycerin fatty acid ester having three or more glycerin molecules, and (E-2) polyhydroxystearic acid, wherein the (A) aqueous component, in the case of being a monohydric alcohol alone, constitutes 1% to 15% by mass relative to the overall amount of the cosmetic, in the case of being a dihydric alcohol alone, constitutes 1% to 20% by mass relative to the overall amount of the cosmetic, and in the case of being a combination of a monohydric alcohol and a dihydric alcohol, a total amount thereof constitutes 1% to 45% by mass relative to the overall amount of the cosmetic.

Provided is a single-phase UV-protective cosmetic containing a non-aqueous volatile component, which has an excellent UV-protective effect after water splashing and perspiration in addition to an excellent UV-protective effect upon application, and also has excellent usability. The single-phase UV protective cosmetic according to the present disclosure contains a dispersant, an ultraviolet absorber, hydrophobic particles, and a non-aqueous volatile component, wherein the dispersant is at least one selected from the group consisting of polyhydroxystearic acid, polyglycerol fatty acid esters, and polyglycerol-modified silicones.

The present application relates to a silicone-free, water-in-oil emulsion comprising: A) a continuous oily phase comprising: i) at least one C12-C22 dialkyl carbonate; and ii) at least one mixture of esters of C8-C10 carboxylic acid(s) and of fatty alcohols derived from coconut oil; and iii) at least one volatile hydrocarbon-based oil; and B) an aqueous phase dispersed in said oily phase; C) at least one emulsifying non-ionic surfactant which is a polyethylene glycol dipolyhydroxystearate containing 30 mol of ethylene oxide, with the INCI name: PEG-30 Polyhydroxystearate; and D) at least one pulverulent colorant chosen from: —mineral pigments chosen from titanium dioxides and iron oxides, which are coated or uncoated, and mixtures thereof, —organic pigments, —pearlescent agents, and mixtures thereof. The invention also relates to a process for coating keratin materials, more particularly for making up and / or caring for keratin materials, such as the skin, characterized in that it comprises the application, to the keratin materials, of a composition as defined above.

A W / O / W type emulsion cosmetic obtained by dispersing a W / O type emulsion containing dipentaerythritol tripolyhydroxystearate in an external water phase containing a water-soluble polymer. The cosmetic has excellent stability over time. Preferably, the water-soluble polymer is a carbomer, an alkyl-modified carboxyvinyl polymer, a water-soluble polymer containing 2-acrylamide-2-methylpropanesulfonic acid or a salt thereof as a constituent unit, a hydrophobically-modified polyether carbamate, and a hydrophobically-modified alkyl cellulose. Preferably, the W / O-type emulsion contains, in the form of droplets, an aqueous solution of a component that is poorly soluble in water when the pH is in the neutral region, and the W / O-type emulsion may be configured from only one type or may be configured from two or more different types of W / O-type emulsions.

The invention discloses a silicone-oil-free water-in-oil emulsified moisturizing rod and a preparation method thereof, and belongs to the field of daily chemical products. The formula consists of a phase A, a phase B, a phase C and a phase D and does not contain silicone oil components, the phase A is an oil phase, the phase B is wax, the phase C is a water phase, the phase D is an anti-corrosion system, a composite polyglycerol emulsifier and PEG-30 dipolyhydroxystearate are cooperatively emulsified, raw materials such as an emollient, a thickening agent and a humectant are matched, and specific temperature control and homogeneous emulsification processes are performed to prepare the silicone oil-free emulsion. The moisturizing rod solves the problems that a silicone oil-free system is unstable in emulsification, the paste is easy to break, the skin feeling is sticky and greasy, and the like, realizes long-acting water locking and refreshing ventilation, is mild and non-irritant, conforms to the green skin care trend, and is suitable for fast-paced life and outdoor nursing scenes.

The invention provides a stable face cleaning composition as well as a preparation method and application thereof, and relates to the technical field of cosmetics. The face cleaning composition disclosed by the invention is prepared from the following components: 27 to 43 parts of polyhydroxystearic acid, 20 to 30 parts of jojoba ester, 8 to 18 parts of sunflower seed wax, 10 to 20 parts of tribehenin, 0.6 to 1.5 parts of PEG-8 beewax, 2.5 to 3.4 parts of beewax and 7 to 15 parts of polyglycerol. All the components are synergistically compounded, the obtained face cleaning composition is applied to preparation of cosmetics and has stable interlayer spacing of an alpha-liquid crystal layered structure, and the stability of the cosmetics is remarkably improved; the face cleaning composition can obviously improve the high-temperature stability of cosmetics.

The present invention provides an anti-scaling agent for reverse osmosis membranes used in sewage treatment and its application. The anti-scaling agent for reverse osmosis membranes comprises the following components in parts by mass: 15-25 parts by mass of a scale inhibitor, 15-20 parts by mass of sodium hydroxide, 0.5-5 parts of polyhydroxystearic acid, and 50-65 parts by mass of water. Compared with the prior art anti-scaling agents, the anti-scaling agent provided by the present invention can increase the limit of preventing the deposition of inorganic salts such as calcium carbonate during the reverse osmosis treatment of sewage. When treating sewage, it can significantly improve the anti-scaling ability of the anti-scaling agent against inorganic salts such as calcium carbonate, thereby improving the treatment effect of the reverse osmosis membrane on sewage.

To provide a metal oxide dispersion composition which has excellent stability over time, excellent non-stickiness, and good usability. The following components (A) to (C): (A) Polyhydroxystearic acid (B) Silicone-treated metal oxide (C) Glyceryl oleate wherein the metal oxide of component (B) is a metal oxide other than titanium oxide.