71 results about "Pulse electric field" patented technology

Devices, systems and methods are provided for treating target tissue with pulsed electric field energy in a manner that does not induce cardiac arrhythmias such as fibrillation of the heart and therefore negates any need for cardiac synchronization of energy delivery. Cardiac synchronization is typically employed to avoid delivering energy during portions of the cardiac cycle that are vulnerable to inducing fibrillation. Thus, herein parameters are manipulated to reduce the probability of inducing an arrhythmia. Typically, high voltage energy can trigger a premature action potential within the cardiac muscle as the delivered energy increases the cardiac muscle cell membrane permeability allowing ion transport, which can induce cardiac arrhythmias, especially ventricular fibrillation. However, both shorter pulse durations (i.e. higher frequencies such as 100-600 kHz) and biphasic waveform shapes theoretically and practically reduce the probability of inducing an arrhythmia.

This invention belongs to the field of grain deep processing technology and discloses a method for reducing the glycemic index (GI) of brown rice flour through a combination of thermal and non-thermal physical processing. The method involves: pulverizing high-quality brown rice and allowing it to stand in equilibrium with water; subjecting the material to low-temperature wet heat treatment at a moisture content of 30%–50%; baking the wet-heat treated material; mixing the baked material with pure water and performing a first freeze-thaw cycle; subjecting the mixture to intermittent pulsed electric field treatment in a multi-cycle intermittent manner; subjecting the pulsed electric field treated material to a second freeze-thaw cycle; and finally centrifuging, drying, sieving, and packaging the material. This method regulates the starch structure to obtain a low glycemic index product through the synergistic effect of a specific sequence of thermal and non-thermal treatments. This invention innovatively designs a two-stage freeze-thaw cycle process before and after the pulsed electric field treatment, employing physical modification methods throughout the process to ensure product safety. It has low equipment requirements and broad industrial application prospects.

The application relates to the technical field of food processing, and particularly discloses a preparation method of high-dietary-fiber konjac beverage, which comprises the following steps: dispersing konjac powder in deoxygenated deionized water, and performing gradient temperature rising and segmented shearing swelling treatment under the protection of inert gas; adding calcium ions into the swelling slurry to perform a micro-crosslinking reaction; performing high-pressure micro-jet nanometer homogenization; performing high-pressure pulsed electric field sterilization treatment on the nanometer micellar dispersion liquid; allowing the slurry after sterilization to stand; and mixing the beverage base liquid with sterile auxiliary materials, and then performing sterile filling. The application adopts gradient temperature rising and segmented shearing swelling treatment to regulate the disentangled state of konjac glucomannan molecular chains, cooperates with calcium ion micro-crosslinking to form controllable intramolecular crosslinking structures, and then converts the nanometer-scale dietary fiber micelles through high-pressure micro-jet nanometer homogenization, so that long-term physical stability and microbial safety of a low-viscosity system are realized while the integrity of the dietary fiber structure is maintained.

The application discloses a kind of dehydration and recycling method of electrolytic manganese dioxide leaching residue, it is related to the field of hydrometallurgy and chemical solid-liquid separation technology.The method is aimed at the technical problems of low dehydration efficiency, insufficient manganese element recovery and high comprehensive energy consumption in the prior art, after neutralization and composite flocculant flocculation of leaching solution, multi-stage electric field treatment is carried out in turn, including applying alternating electric field in the sedimentation tank for pre-aggregation, applying direct current electric field in plate and frame filter press for pressure filtration dehydration and applying pulse electric field before unloading for deep dehydration, finally unload filter cake and collect filtrate.The method is mainly used for efficient dehydration of leaching residue in the production process of electrolytic manganese dioxide and maximization of manganese resource recovery, to realize energy saving and emission reduction and resource recycling.

The application belongs to the technical field of medical devices, and particularly relates to a negative pressure wound dressing system based on an alternating pulse electric field. The system comprises a dressing system main controller, a directional electric field dressing and a heart rate monitoring sensor. The main controller comprises an alternating pulse generator and two pulse current circuits, which are connected to a first electrode and a second electrode on the dressing respectively. The core technology is that the system controls the alternating pulse generator to periodically switch the current direction between the two pulse current circuits according to the heart rate value measured by the heart rate monitoring sensor, so as to dynamically change the application direction of the alternating pulse electric field applied to the wound. The system can realize adaptive switching of the electric field direction according to the physiological state (such as rest / activity) of the patient, and can optionally integrate a negative pressure drainage function. The dressing system provided by the application can provide dynamic electric stimulation more in line with the individual physiological rhythm, and aims to realize intelligent and personalized wound treatment to promote tissue repair.

The application discloses an oil agent equipment cleaning waste liquid treatment device and method, and relates to the field of oil agent waste liquid treatment. The device comprises an electric field demulsification mechanism in communication with a waste liquid pipe, wherein a pulse electrode is arranged in the electric field demulsification mechanism, a composite reactor is arranged on the downstream side of the electric field demulsification mechanism, an anaerobic bacteria area, a lower grid, a transverse partition plate, an upper grid and an aerobic bacteria area are arranged from bottom to top in the electric field demulsification mechanism, and the electric field demulsification mechanism is further provided with an aeration assembly, a monitoring and shunting system and a gas collecting mechanism. The treatment method comprises the following steps: electric field demulsification pretreatment, aeration, aerobic / anaerobic microbial degradation, multi-parameter monitoring and shunting treatment. According to the application, secondary pollution is avoided through pulse electric field demulsification, pollutants are degraded in stages by using an anaerobic-aerobic linkage circulation structure, real-time monitoring and intelligent shunting are combined, and the treatment efficiency is improved and the operation cost is reduced.

The application discloses a surimi purification system and method based on electric field assisted membrane separation, which comprises a raw material pretreatment module, a controllable pressure pulse electric field module and a membrane separation coupling module.

The application discloses a preparation method of carbon-reinforced high-performance magnesium alloy and relates to the technical field of new material preparation of magnesium alloy. The magnesium alloy powder is used as raw material, phenolic resin is uniformly coated on the surface of magnesium alloy powder particles, then the coated magnesium alloy powder is heated to 700 DEG C under the induction of a pulse electric field, the phenolic resin is decomposed and carbonized, and a carbon network structure is formed in the magnesium alloy matrix, the magnesium alloy melt is pressure-formed in a preheated forming mold after heat preservation for 30 minutes, and the carbon-reinforced high-performance magnesium alloy material is obtained.

This invention provides a method and apparatus for preparing sodium ferrochlorophyllin using green organic acid-assisted membrane separation, relating to the fields of chemical separation and pharmaceutical raw material refining. The method first utilizes a green organic acid to construct a supramolecular micelle system, inducing high monomer-level dispersion of chlorophyllin molecules through a hydrogen bond network, thus solving the problem of hydrophobic aggregation in an aqueous environment. Then, an electrocoupled ceramic membrane reactor is employed, utilizing the physical confinement effect of nanopores to force microscopic deformation of the porphyrin ring, combined with a transmembrane alternating pulsed electric field to achieve targeted complexation of iron ions, overcoming the high energy barrier of steric hindrance in central ion replacement. Finally, based on a constant-volume cross-current dialysis and reverse osmosis coupling mechanism, macromolecular products are distinguished from small-molecule impurities, achieving closed-loop circulation of the organic acid solvent and precise product purification. This invention effectively solves the bottlenecks of active site masking and membrane fouling, significantly improving preparation efficiency, product purity, and the greening level of the production process.

The present application relates to a method for improving the thawing quality of quick-frozen fresh-cut potatoes, and belongs to the technical field of fruit and vegetable freezing processing. The main steps of the present application include: raw material selection; pretreatment; preparation of a composite osmotic dehydration color protection agent; variable-temperature negative pressure ultrasonic assisted enzyme inactivation; gradient magnetic field assisted quick freezing; packaging; frozen storage; pulse electric field assisted high-humidity low-temperature anaerobic thawing. The present application realizes effective preservation of the quality of quick-frozen fresh-cut potatoes after thawing by innovatively adopting vacuum ultrasonic assisted low-temperature enzyme inactivation, gradient magnetic field assisted quick freezing and pulse electric field assisted high-humidity low-temperature anaerobic thawing, so that the hardness of the thawed frozen fresh-cut potatoes is increased by more than 10%, the browning is reduced by more than 10%, and the juice loss rate is controlled within 11%.

The application discloses a kind of based on graphene coating infrared synergistic efficient composite drying method of fruit freeze-drying, the method includes the following steps: S1.fruit is in the pulsed electric field of pulse voltage 35 kV / cm below and is pretreated, and the fruit after pulsed electric field pretreatment is obtained;S2.pretreated fruit is in the electrostatic field of field intensity 30 kV / cm below and is pre-frozen, and the fruit after pre-freezing is obtained;S3.pre-frozen fruit is placed on graphene coating hot plate, and is dried under vacuum condition, and the freeze-dried fruit is obtained;The heating rate of graphene coating hot plate is 2~5℃ / min, heating temperature is 30~50℃, and drying time is 8~12 h.The fresh fruit is sequentially treated by pulsed electric field, electrostatic field assisted directional freezing treatment and graphene coating infrared heating drying process synergy, so that freeze-dried fruit nutrient retention rate is high, rehydration is good, and freeze-drying cycle is shortened by 25~45%, energy consumption is reduced by 25~40%, suitable for efficient high-quality energy-saving drying processing of fresh fruit.

The present invention relates to a balloon electrode catheter, and specifically to a flexible circuit of a balloon electrode assembly in the balloon electrode catheter. The flexible circuit comprises an insulating substrate, electrode plates and a trace, wherein the insulating substrate is configured to be attached to a balloon of the balloon electrode assembly, and has a bending degree that changes along with the inflation and deflation of the balloon; the electrode plates are fixed to the insulating substrate for generating a pulsed electric field; the trace is located inside the insulating substrate for connecting the electrode plates to corresponding circuits; and the trace comprises at least one branch trace, the branch trace being arranged side by side with at least one electrode plate along an extended surface of the insulating substrate, and being connected to another electrode plate, such that electrical connection of corresponding electrode plates is achieved by means of the branch trace. Said solution is conducive to reducing the hardness of the flexible circuit, such that the flexible circuit can deform more easily when subjected to resistance in the process of entering or exiting a sheath, so as to avoid serious interference with the sheath, thus making it convenient for the balloon electrode assembly to enter or exit the sheath.

The application provides a preparation method and application of konjac fine powder. The preparation method of the konjac fine powder comprises the following steps: A1. konjac powder obtained by crushing konjac dry is mixed with water at 60-75 DEG C to perform infiltration swelling, a pulse electric field treatment is applied at 15-30 kV / cm, and then solid-liquid separation is performed to obtain wet konjac slurry; A2. the wet konjac slurry is subjected to dynamic countercurrent extraction by using supercritical CO2 containing ethanol under the conditions of 45-60 DEG C and 25-35 MPa, and then sulfides and pigments are removed to obtain extracted wet konjac slurry; and A3. the extracted wet konjac slurry is subjected to low-temperature vacuum drying and airflow crushing to obtain konjac fine powder. Through the dissolution capacity of supercritical CO2 and the cell wall breaking and bleaching effects of the pulse electric field, the konjac fly powder, sulfides and colored substances are efficiently physically stripped and removed without using any harmful chemical reagent, and the natural molecular structure and viscosity of konjac glucosaccharide are retained.

This invention discloses a pulsed electric field ablation electrode with an integrated triggerable embedded drug ring, relating to the field of medical device technology. The electrode includes a 3D-printed embedded drug ring, an electrode substrate, an electrode tip, and an annular groove. The electrode tip is located at the end of the electrode substrate and has an annular groove. The 3D-printed embedded drug ring carries an antitumor drug, is fixed to the annular groove, and its outer surface forms a smooth and continuous working surface with the electrode substrate. This invention can simultaneously achieve targeted drug release when a high-voltage pulsed electric field is applied for ablation, integrating pulsed electric field ablation with local drug delivery functions. This solves the problem of the single function of traditional electrodes. In scenarios such as percutaneous or open ablation of liver cancer and endoscopic ultrasound ablation of pancreatic cancer, it can achieve precise synergy between physical ablation and chemotherapy / immunotherapy, effectively improving the tumor treatment effect.

The application provides a steep pulse electric field ablation circuit and a control method thereof. The FPGA processor in the circuit is connected with a high-voltage direct-current power supply, a pulse controller and a high-voltage isolation measurement circuit respectively. The first output end and the second output end of the high-voltage direct-current power supply are connected with the first input end and the second input end of a steep pulse generation module respectively. The first output end of the pulse controller is connected with the third input end of the steep pulse generation module, and the second output end of the pulse controller is connected with the fourth input end of the steep pulse generation module. The first output end and the second output end of the steep pulse generation module are connected with two ends of a load respectively, and the two intersection points are connected with the first input end and the second input end of the high-voltage isolation measurement circuit respectively. The circuit realizes accurate measurement and stable control of the high-voltage output amplitude.

This invention provides a high-antioxidant perfluorosulfonic acid composite cation exchange membrane, its preparation method, and its applications, belonging to the field of membrane separation materials technology. This invention impregnates an asymmetric bilayer porous support, resulting in a high ion flux in the low-density region and a high ion conduction efficiency in the high-density region, thus enabling the perfluorosulfonic acid composite cation exchange membrane to possess both excellent antioxidant properties and ion flux. This invention utilizes a pulsed electric field to directionally regulate the distribution of sulfonic acid groups, creating a low-density sulfonic acid group exposure region on the oxidizing side of the electrode membrane and a high-density sulfonic acid group enrichment region on the non-oxidizing side, forming a protective zone and improving the antioxidant tolerance of the perfluorosulfonic acid composite cation exchange membrane. The impregnation solution used in this invention includes a perfluorosulfonic acid resin solution and modified antioxidant nanofillers. Under the action of the impregnation electric field, a dual protection of "low-density sulfonic acid group exposure + sacrificial layer of filler" is achieved, resulting in more stable performance of the electrode membrane in complex electrochemical environments.

This invention discloses a method and apparatus for enhancing microbial catalytic degradation of chlorinated hydrocarbons in groundwater using a pulsed electric field, relating to the field of groundwater pollution remediation technology. By introducing microbial stimulants, including nutrients and electron donors, into the polluted groundwater area to enhance the activity of functional microorganisms, and applying a pulsed electric field to create a dynamic potential gradient, the method promotes pollutant migration and microbial metabolism, achieving a stepwise degradation of chlorinated hydrocarbons from highly chlorinated intermediates to low-chlorinated intermediates and ultimately to non-toxic alkanes. Simultaneously, monitoring data such as pollutant concentration, environmental parameters, and microbial activity are collected, and the pulsed electric field parameters and stimulant addition strategy are dynamically adjusted based on this data to match external stimulation with dechlorination requirements. This promotes the continuous and efficient conversion of highly chlorinated hydrocarbons to low-chlorinated hydrocarbons and ultimately to non-toxic alkanes, improving electron utilization efficiency and system stability, shortening the remediation cycle, and reducing energy consumption and the risk of secondary pollution.

A method and a pulsed electric field (PEF) ablation instrument are provided. According to one aspect, a method in a PFA generator includes receiving electrical responses for each of at least one non-therapeutic waveform. The process also includes determining an electric field distribution based at least in part on the received electrical responses. The process further includes selecting a non-therapeutic waveform that produces an electric field distribution that satisfies criteria. The process also includes mapping the selected non-therapeutic waveform to an ablative waveform.

The application provides a high-oxidation-resistance perfluorosulfonic acid composite cation exchange membrane and a preparation method and application thereof, and belongs to the technical field of membrane separation materials.The asymmetric double-layer porous support is immersed, a larger ion flux is obtained in a low-density area, and a larger ion conduction efficiency is obtained in a high-density area, so that the perfluorosulfonic acid composite cation exchange membrane has excellent oxidation resistance and ion flux.The application utilizes a pulse electric field to directionally regulate and control sulfonic acid group distribution, so that the oxidation side of the membrane is a sulfonic acid group low-density exposure area, the non-oxidation side is a sulfonic acid group high-density enrichment area, a protection area is formed, and the oxidation resistance and tolerance of the perfluorosulfonic acid composite cation exchange membrane are improved.The immersion solution used in the application comprises a perfluorosulfonic acid resin solution and modified oxidation-resistant nano fillers, and under the action of an electric field in the immersion, double protection of'sulfonic acid group low-density exposure + filler sacrificial layer' is realized, and the performance of the membrane is more stable in a complex electrochemical environment.

The application relates to a microfluidic on-demand encapsulation device and method based on target object arrival prediction, which comprises a microfluidic channel assembly, a micro-particle detection unit, a local electric field actuating unit, a controller and a fluid driving unit. The micro-particle detection unit is arranged in a detection area upstream of a dispersed phase jet flow forming area. The local electric field actuating unit is arranged in a region adjacent to a droplet breaking window. The electric field is limited from spreading to the detection area and is concentrated on the region adjacent to the droplet breaking window. The controller predicts the expected arrival time of the target object according to the migration time from the detection area to the droplet breaking window. The starting trigger time of the pulse electric field is determined based on the advance trigger compensation amount. When the number of detected target objects reaches a preset target value, the pulse electric field is applied to the region adjacent to the droplet breaking window, the matching degree between the actual droplet breaking time and the expected arrival time of the target object is improved, and the on-demand encapsulation of the target object is realized.

The present application relates to the technical field of water quality monitoring, and discloses a water sample pollution inspection method guided by microorganism detection, comprising: applying a pulsed electric field to a biochemical response system to reduce the mass transfer resistance of the cell membrane of an indicator microorganism by using a physical pore-forming effect; injecting a fluorescent substrate and synchronously collecting fluorescence emission intensity and backscattering light intensity; correcting the amplitude of the fluorescence emission intensity by using the backscattering light intensity to eliminate physical shielding interference and obtain a pre-steady-state fluorescence emission sequence; intercepting a characteristic value of the change rate of the pre-steady-state fluorescence emission sequence to calculate an intrinsic catalytic turnover index representing the specific catalytic activity of intracellular enzymes, and determining the pollution degree of the water sample to be tested according to the offset of the index relative to a preset reference value; and the present application can quickly identify pollutants with transmembrane mass transfer disorders and eliminate the influence of endogenous activity fluctuations of microorganisms on the detection result by means of the cooperation of electric pore-forming intervention and calculation logic.

The application discloses a kind of electric field induction-iron ion embedding type iron sodium phaeophytin preparation method and device.The method includes plant raw material slurry, pulse electric field wall breaking extraction, saponification forms chlorophyllin precursor liquid, using three-cavity membrane separation electric field reactor carries out bipolar membrane in-situ demag, iron anode electrochemistry releases iron and migrates to central coordination reaction cavity by cation exchange membrane, completes embedding iron under the control of pulse electric field and oxidation-reduction potential, then is salted by sodium, microfiltration, ultrafiltration, electrodialysis desalination and drying to obtain iron sodium phaeophytin product.The device includes raw material slurry module, pulse electric field processing module, saponification reaction module, membrane separation electric field reaction module, salted by sodium module, purification module, drying module and central controller.The application process is continuous, iron supply is controllable, demag and embedding iron are closely coupled, and is suitable for industrial implementation.

This invention provides a functional fascia gun head, belonging to the field of massage devices and physical therapy technology. This functional fascia gun head consists of a power-generating layer and a regular fascia gun head; the power-generating layer can be placed outside or inside the regular fascia gun head. Another design of the functional fascia gun head is entirely composed of a power-generating layer. When the fascia gun is in operation, the power-generating layer generates a Maxwell pulse electric field and a pulse displacement field current under force, forming a pulse wave. This pulse wave can effectively penetrate multiple layers of skin structure, promoting blood circulation and cell activation, achieving various health benefits such as warming the meridians and activating collaterals, relaxing muscles, relieving pain, preventing injury, dispelling cold and dampness, harmonizing yin and yang, promoting homeostasis, and delaying aging. The power-generating layer is made of various materials and has various structural forms; the manufacturing process is simple, significantly improving the product's multifunctionality and ease of use, providing more diversified and efficient options for the medical and beauty fields.

This invention belongs to the field of medical device technology, and specifically relates to a pulsed field ablation catheter system for coronary artery myocardial bridging. It includes a pulsed electric field ablation structure and a disposable pulsed electric field ablation catheter. A connecting wire is located on the back side of the pulsed electric field ablation structure, and the other end of the connecting wire is movably engaged with the disposable pulsed electric field ablation catheter. By using the disposable pulsed electric field ablation catheter, the catheter body drives an inflatable balloon through the arterial tube to reach the myocardial bridging lesion. The contrast fluid injected into the external tube gradually expands the balloon, causing it to unfold and allowing the electrode pads to adhere to the vessel wall for pulsed electric field ablation. This eliminates the need for the strong adhesion required by traditional thermal or cold ablation, effectively avoiding vascular damage caused by excessive local energy, and providing an efficient and reliable solution for the clinical treatment of coronary artery myocardial bridging.

This invention provides a self-generating ulcer dressing, belonging to the field of medical device technology. The self-generating ulcer dressing comprises a self-generating layer and a conventional ulcer dressing. The conventional ulcer dressing includes a medicated layer and a protective layer, with the self-generating layer either independently between or integrated with both. The self-generating layer is composed of membrane materials such as polylactic acid, polarized cellulose dressing, and polyvinyl alcohol, either alone or in combination with other strongly electronegative biocompatible materials. It generates a Maxwell pulse electric field under external force, accelerating cell regeneration and tissue repair, and promoting ulcer healing. The self-generating layer can be combined with the medicated layer or the protective layer. The protective layer material can be selected from polyacrylic acid resin, diethyl phthalate, or hydroxypropyl methylcellulose, etc. The self-generating ulcer dressing can have a multi-layered or staggered structure, with layers connected by coating, mixing, or compression. The self-generating ulcer patch of the present invention has a flexible design and does not require an external power source. When the self-generating ulcer patch is continuously rubbed and pressed, the self-generating layer is subjected to continuous force to generate a Maxwell pulse electric field and a pulse field current, which can activate cells, promote blood circulation, and work synergistically with ulcer medication to accelerate cell regeneration and tissue repair, thereby achieving the effect of promoting ulcer wound healing.

The application belongs to the technical field of alloys, and provides a method for improving wear resistance of ADC12 recycled aluminum alloy. 2 Wherein, the current density of the pulse electric field treatment is not 0. The pulse electric field is applied to the ADC12 recycled aluminum alloy, electrons interact with crystal defects, atom diffusion is accelerated, dislocation movement is improved, phase change energy potential barrier is reduced, plastic deformation of the ADC12 recycled aluminum alloy is generated, and deformation capacity is improved. The pulse electric field refines solidification structure of the ADC12 recycled aluminum alloy through electron migration effect, Seebeck effect, magnetic shrinkage effect, skin effect, electronic wind power and inoculation modification effect, and wear resistance of the ADC12 recycled aluminum alloy is improved.

This invention provides a self-generating adhesive bandage, belonging to the field of medical supplies technology. The self-generating adhesive bandage consists of a power-generating layer and a conventional adhesive bandage, including but not limited to an adhesive layer, an absorbent pad, and a separating permeable membrane or release paper. When the self-generating adhesive bandage is continuously rubbed and pressed, the power-generating layer generates a Maxwell pulse electric field and pulsed current under continuous force, accelerating cell regeneration and tissue repair, and promoting wound healing. The power-generating layer can be independently disposed between these layers, or it can be fused with one or more layers. The power-generating layer is composed of membrane materials such as polytetrafluoroethylene (PTFE), polyvinylidene fluoride (PVDF), and perfluoroethylene propylene copolymer (FEP), or composites with other materials. The self-generating adhesive bandage can have a multi-layered or interlaced structure, with layers fixed by adhesive bonding or thermoforming. This invention requires no external power source and can generate a Maxwell pulse electric field through simple external force, thereby accelerating cell regeneration and tissue repair, achieving the effect of promoting wound healing, simplifying the operation process, and improving the convenience and safety of use. At the same time, the manufacturing process of this invention is relatively simple and easy to scale up for mass production.

The application discloses a kind of GCr15 bearing steel's electric field auxiliary large heterogeneous organization preparation method;Method includes: rare earth GCr15 bearing steel is heated to 800~950 DEG C, and keeps warm;Subsequently, hot billet is mechanically deformed, and dislocation is generated at the interface of matrix and non-metallic inclusion;Pulse electric field is applied to the billet after deformation, and the gathering effect of electric current is used to generate local joule heat near dislocation, so that the temperature of interface micro area is instantaneously increased to above recrystallization temperature, while the whole matrix keeps lower temperature;Under the action of joule heat, the interface region where dislocation is dense occurs dynamic or static recrystallization, forms fine equiaxed crystal layer, and the fine equiaxed crystal layer can effectively relax stress concentration at the interface, inhibit crack initiation;Cool to room temperature, obtain bearing steel material.The application realizes the active regulation of large heterogeneous structure interface by alloy design and preparation process optimization, and is suitable for the industrialization production of high reliability bearing steel.

This invention belongs to the field of food processing technology, specifically relating to a low molecular weight *Hydrangea hygroscopica* polysaccharide microsphere for relieving fatigue, its preparation method, and its application. The preparation method includes the following steps: (1) extraction of crude polysaccharide from *Hydrangea hygroscopica*; (2) degradation; (3) encapsulation: the low molecular weight *Hydrangea hygroscopica* polysaccharide obtained in step (2) is dripped into CaCl2 solution through electrospray treatment to form a gel core, and the gel core is encapsulated to obtain the low molecular weight *Hydrangea hygroscopica* polysaccharide microspheres. The beneficial effects of this invention are: this invention efficiently extracts *Hydrangea hygroscopica* polysaccharide through steam explosion-pulsed electric field synergy, accurately prepares 10-20 kDa high-activity low molecular weight fragments through compound enzymatic hydrolysis-ultrasound-ultrafiltration, and finally constructs colon-targeting microspheres using electrospray-layer-by-layer self-assembly. These microspheres can protect the active ingredients and allow them to reach the colon for release, significantly improving the bioavailability and anti-fatigue effect of the polysaccharide.