954 results about "Pulse electric field" patented technology

The invention discloses a flocculation treatment device and method for removing high turbidity of a water sample. The method comprises the following steps: monitoring an inflow turbidity parameter in real time, continuously collecting original optical characteristic data of water through an optical sensor array, and calculating a turbidity fluctuation rate parameter after noise reduction treatment; carrying out graded rotational flow mixing treatment, forming a pressure gradient through three stages of tapered rotational flow pipes in sequence, activating an ultrasonic frequency field, and synchronously adding main and auxiliary flocculants; the method comprises the following steps: introducing a water sample into a multi-stage gradient flocculation reaction zone, and sequentially executing turbulent flow enhanced flocculation, slow stirring flocculation and pulsed electric field assisted flocculation to form a floc structure with different particle size distribution; running parameters of a sedimentation module are adjusted according to real-time effluent turbidity feedback, and the inclination angle of an inclined plate assembly and the opening degree of a mud discharging valve are dynamically adjusted; a parameter set is updated through a prediction model based on periodically collected system operation data, a closed-loop optimization control strategy is formed, the adaptability to extreme turbidity is enhanced, the solid-liquid separation efficiency is improved, the overall energy consumption is reduced, and the efficient and stable requirements of emergency treatment are met.

The invention belongs to the field of blood product separation, and discloses a high-efficiency chromatography system and method for blood product separation, and the system comprises an intelligent chromatography column module, an automatic sample injection and accurate flow rate control module, a chromatography filler and column design module, a real-time detection and data analysis module, and an intelligent automatic control and management module. By designing an efficient micro-nano filler chromatographic column and matching with a pulsed electric field auxiliary technology and intelligent automatic control, efficient and high-purity separation and purification of target blood product components are realized. The intelligent regulation and control module used in the invention can dynamically regulate chromatography conditions in real time, and the problems of unstable flow velocity and column pressure in the traditional method are thoroughly solved. And meanwhile, a multi-point real-time detection and feedback technology is adopted, so that the separation process is more accurate, transparent and controllable.

Methods, systems and devices are provided which transmit energy to a body lumen or passageway in the form of pulsed electric fields (PEFs) and in a manner which provides focal therapy. In some embodiments, PEFs are delivered through independent electrically active electrodes of an energy delivery body, typically in a monopolar fashion. Such delivery concentrates the electrical energy over a smaller surface area, resulting in stronger effects than delivery through an electrode extending circumferentially around the lumen or passageway. It also forces the electrical energy to be delivered in a staged regional approach, mitigating the effect of preferential current pathways through the surrounding tissue. Focal delivery of PEFs can provide increased tissue lethality by employing precise timing and sequencing of energy delivery to the electrodes.

Systems, devices, and methods for electroporation ablation therapy are disclosed. A device may include a linear shaft including a distal portion positionable near a tissue wall. The linear shaft may be configured to deflect to position the distal portion near the tissue wall. The device may include a plurality of electrodes disposed on the distal portion of the linear shaft, wherein the plurality of electrodes are configured to generate a pulsed electric field that produces an ablation zone in the tissue wall having a depth that is independent of the orientation of the distal portion relative to the tissue wall.

The invention relates to the field of medical physics, and discloses a control method and system for pulse electric field ablation of duodenum, and the method comprises the steps: determining a multi-target tissue, needing pulse electric field ablation, of the duodenum corresponding to a target user, collecting a target tissue image of the multi-target tissue, and constructing a multi-tissue three-dimensional model of the multi-target tissue; analyzing tissue parameters of the multi-target tissue, and analyzing electric field intensity and pulse parameters required for ablation of the multi-target tissue; multiple electrodes of the ablation equipment are configured, and multiple electrode implantation sites of the multiple electrodes are determined; constructing a digestive tract model from the corresponding oral cavity to the duodenum of a target user, analyzing an ideal transmission path of multiple electrodes, analyzing a path deviation coefficient of a simulation transmission path and the ideal transmission path, correcting the simulation transmission path, transmitting the multiple electrodes to a multi-electrode implantation site, and then performing multi-electrode implantation. And pulse electric field ablation of multi-target tissues is realized by utilizing multiple electrodes. The precise ablation effect of the pulsed electric field can be improved.

Devices, systems and methods are provided for treating conditions of the heart, particularly the occurrence of arrhythmias, more particularly atrial fibrillation. Therapeutic pulsed electric field energy is delivered to portions the heart to provide tissue modification, particularly to the entrances to the pulmonary veins in the treatment of atrial fibrillation. Such tissue modification creates a lesion or series of lesions which act as a conduction block within the tissue to prevent the transmission of aberrant electrical signals. Cardiovascular lesion analysis systems and methods provide information related to the effectiveness of the treatment during the procedure so as to create an electrical blockade within the heart that will remain durable and effective long-term.

The invention relates to a kitchen waste oil recovery treatment method, which comprises: S1, carrying out multi-field synergistic pretreatment: sequentially carrying out ultrasonic wave and high-frequency pulse electric field treatment on waste oil to break an emulsion layer, adding magnetic nanoparticles to adsorb polar impurities, and carrying out magnetic field separation to obtain high-purity oil; s2, supercritical catalytic reaction: under the CO2 supercritical condition, using a core-shell structure composite catalyst to synchronously perform transesterification reaction and glycerol dehydration reaction; s3, dynamic membrane separation: separating biodiesel and glycerol in real time through an intelligent membrane assembly; s4, gradient utilization of energy: recovering reaction waste heat to drive membrane distillation to concentrate wastewater, and using tail gas CO2 for carbonation reaction to generate calcium carbonate. Through four core technologies of multi-field collaborative pretreatment, low-temperature supercritical catalysis, dynamic membrane separation and energy gradient utilization, triple limitations on efficiency, cost and environmental protection in the prior art are remarkably broken through.

Treatment of damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) is provided by delivering specialized pulsed electric field energy to target tissue areas in a specific dose so as to obtain a superior outcome. The specialized PEF energy and delivery has been optimized to provide advanced treatment of target tissue areas, including destruction of undesired tissue and generation of improved inflammatory and immune responses. The specialized PEF energy provides superior outcomes to radiofrequency ablation and irreversible electroporation.

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

The invention discloses an electro-optical-acoustic cooperative partial discharge detection device and method, and belongs to the field of equipment discharge fault detection. The device integrates a high-frequency current detection module, a photoelectric coupling detection module and an acoustic emission detection module; a high-frequency pulse current signal of a cable grounding loop, a pulse electric field of an insulating surface and an ultrasonic signal in a solid medium can be collected at the same time; all the collected signals are sent to the signal integrated processing module for alignment, noise reduction and multi-signal homologous conformity test; after detection, the signal integration processing module extracts combined feature vectors from the signals and inputs the combined feature vectors to the classification discriminator; finally, the discriminator outputs the probability of partial discharge, and if the probability exceeds a preset threshold value, it is judged that partial discharge exists in the cable. Therefore, by implementing the method and the device, the problems that single-mode detection in the prior art is poor in anti-interference capability in a complex field environment, and false alarm or missing alarm is easy to occur can be solved.

The invention discloses a preparation method and application of a pulsed electric field induced high-thermal-conductivity epoxy-based composite material, and relates to the technical field of preparation of epoxy resin composite materials. The invention aims to solve the problem that the thermal conductivity of the epoxy resin-based composite material is not obviously improved under the condition of low filling amount at present. According to the method, the h-BN is induced to be oriented in an epoxy resin matrix by utilizing a pulsed electric field, then the epoxy resin is cured, and the oriented structure is reserved. Compared with blindness of construction of a direct doping heat conduction path, the h-BN is enabled to face a specific direction by utilizing an induction effect of a pulsed electric field, so that the probability of mutual lap joint of the h-BN is increased, and construction of the heat conduction path is promoted. The preparation method and application of the high-thermal-conductivity epoxy composite material induced by the pulsed electric field can be obtained.

Systems, devices, and methods described herein relate to catheter devices for therapy delivery. In some embodiments, a catheter device includes an expandable electrode and a needle, where the needle can be advanced distal to a distal end of the expandable electrode and inserted into a tissue site. The expandable electrode and the distal end of the needle can be configured to deliver electroporation to the tissue site.

The invention discloses a method for preparing ultra-high-purity quartz by multi-stage synergistic purification of quartz ore, and belongs to the technical field of ultra-high-purity quartz preparation. According to the method, natural quartz ore is used as a raw material, mineral impurities, lattice impurities and inclusions in quartz are deeply removed through multi-stage synergistic processes such as low-temperature plasma activation, biological leaching, supercritical CO2-assisted acid leaching, microwave-assisted chloridizing roasting and pulsed electric field enhanced acid leaching, and finally a high-purity quartz product with the SiO2 purity larger than or equal to 99.998% (4N8 grade) is obtained. According to the invention, a low-temperature plasma activation technology, microbial metallurgy, supercritical fluid extraction and a pulsed electric field strengthening technology are organically combined, so that the energy efficiency bottleneck and environmental protection limitation of a traditional high-purity quartz preparation process are broken through; the obtained quartz sand product can reach the standards of high-purity quartz sand for semiconductor quartz glass and high-purity quartz sand for photovoltaic quartz crucibles.

The invention discloses a novel electrolytic tank pipeline filter and a self-cleaning system. The novel electrolytic tank pipeline filter comprises a multi-stage filtering part, the self-cleaning system and an intelligent control system, the multi-stage filtering part comprises multi-stage filter elements arranged in the material pipeline, and the multi-stage filter elements are arranged from large to small according to the filtering particle size to form a filtering gradient; the self-cleaning system acts on the multi-stage filter element part at the same time or in a time-sharing manner on the basis of a fluid reverse recoil principle; the self-cleaning system is combined with pulsating flushing control, so that the filter element is separated from a filter cake at low loss; the multi-stage gradient filtration is adopted, impurities are efficiently and accurately intercepted, the filter elements with the particle sizes from large to small are arranged in a gradient mode, the first-stage titanium alloy filter element intercepts large particles, the second-stage polytetrafluoroethylene membrane filters tiny impurities, the efficiency is improved through graded interception, the loss of the filter elements is reduced, and the material purity and the hydrogen production quality are guaranteed. The multi-element self-cleaning technology is adopted, low-loss deep cleaning is achieved, and the self-cleaning system integrates multiple technologies such as fluid reverse backflushing, pulsating flushing, ultrasonic vibration and a pulsed electric field.

Disclosed in the present invention is an ablation system. The ablation system comprises: a radio frequency generation module, which is used for generating a radio frequency output; a pulse generation module, which is used for generating a pulse output; an output control module, which is used for choosing, according to a characteristic of an ablation region, between ablation output modes, namely, radio frequency output and pulse output; and an ablation consumable, which is used for performing output for the ablation region according to the ablation output mode, which is selected by the output control module. According to the ablation system of the present invention, radio frequency ablation technology can be combined with pulsed electric field ablation technology, such that different application requirements in a clinical surgical operation are better met.

The invention relates to the technical field of pulse electric field measurement, and discloses a time drift compensation method of a pulse electric field measurement system based on model parameterization. According to the method, a parameterized model is constructed in simulation software, and the parameterized model is additionally provided with two servo zeroing compensation circuits on the basis of an original measurement system, and the two servo zeroing compensation circuits are connected to the output ends of two in-phase operational amplification circuits respectively to form a negative feedback loop used for dynamically suppressing low-frequency baseline drift; acquiring electric field time domain waveform data of the output end of the third in-phase operational amplifier circuit; calculating a transfer function of a pulsed electric field measurement system in the parameterized model, converting the transfer function from a frequency domain state to a time domain state through inverse Fourier transform, and then performing deconvolution on the transfer function of the time domain state and electric field time domain waveform data to obtain real electric field intensity; according to the invention, time drift caused by operational amplifier input imbalance, power supply fluctuation and temperature change is automatically compensated in real time, and the stability and precision of system measurement are improved.

The invention provides a duodenal mucosa adjusting system and method based on pulsed electric field ablation and application of the duodenal mucosa adjusting system and method in diabetes treatment, the duodenal mucosa adjusting system comprises an intelligent control host capable of achieving bidirectional data transmission and an adjustable catheter, and the intelligent control host initializes parameters and adjusts pulse parameters by monitoring impedance data in real time until pulses are interrupted or terminated; periodic ablation is carried out, periodic intervals are used for measuring impedance data, the ablation depth is evaluated according to the impedance change rate, and whether next section ablation is carried out or not is judged till full-area ablation is completed. The far-end ablation adopts a structure of combining fusiform flexible support and annular electrode spiral arrangement to ensure that an ablation field uniformly covers mucous membrane plica of a duodenum bulb part and a descending part; a cell selective ablation mechanism is adopted, the critical electric field intensity is set, K cell electroporation is selectively induced, and meanwhile goblet cells are protected.

The invention discloses an irreversible electroporation damage assessment system and method based on myocardial dielectric properties, solves the problem of how to assess damage in a pulsed electric field ablation process, and belongs to the technical field of medical equipment. The system comprises an acquisition module and a workstation, wherein the acquisition module acquires an intracardiac ECG signal, a global electric field voltage signal of a target cardiac cavity, and impedance and temperature between ablation electrode pairs in real time; the work station processes the collected signals to obtain electrocardio characteristics, ablation parameters, temperature between the ablation electrode pairs, impedance drop, contact force and contact state between the ablation electrode pairs and myocardial tissue and ablation electrode position stability, the obtained signals are input into the evaluation model, and the evaluation model outputs IRE injury evaluation classification results. The evaluation model is realized based on a neural network. And real-time measurement and evaluation are carried out on PF ablation injury so as to assist a user to complete comprehensive, objective and accurate evaluation of the ablation effect.

The present invention discloses a method and device for determining ablation parameters for high-frequency pulse electric field ablation. The method comprises: acquiring collected medical image data containing depth information, determining a corresponding lesion box containing three-dimensional information of the lesion based on the medical image data; analyzing and segmenting the lesion box to obtain the contour and depth of the lesion and the contour of the electrode used to ablate the lesion; starting from a plurality of equally spaced points on the boundary of the electrode contour, emitting a preset number of rays to the surrounding area, obtaining the number of intersections between the rays and the lesion box to determine whether the electrode and the lesion are in contact; when the electrode and the lesion are in contact, determining the corresponding ablation parameters based on the contour and depth of the lesion, the ablation parameters including pulse voltage, pulse width, number of pulse trains, and number of discharges. The present invention solves the problem of inaccurate ablation parameter determination in the prior art.

Treatment of damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) is provided by delivering specialized pulsed electric field (PEF) energy to target tissue areas in a specific dose so as to obtain a superior outcome. The PEF energy and delivery has been optimized to provide advanced treatment of target tissue areas, including destruction of undesired tissue and generation of improved inflammatory and immune responses. These various types of treatment are controlled by a variety of factors including the electrode geometry, the dose of PEF energy delivered, the time the energy is delivered over, and the waveform of the PEF energy itself. The PEF energy is delivered in the form a dose which is considered to be one application of the specialized energy. Each dose creates a lesion in the target tissue area.

The present invention discloses a gradient structure 3D printed metal component and its preparation process, belonging to the field of 3D printing forming preparation. The preparation process of the present invention includes: 1) 3D printing material preparation, 2) 3D model construction and parameter setting, 3) 3D printing forming, 4) mechanical treatment, 5) surface treatment, and finally obtaining a 3D printed metal component with a dense surface without pores and excellent mechanical properties. The present invention solves the problems of material surface densification and pores by introducing laser peening technology into the preparation process of 3D printed metal components, and solves the problem of crack propagation by introducing a pulsed electric field during the laser peening process, thereby preparing high-quality gradient structure 3D printed metal components.

The invention discloses a separation and purification method of soy sauce flavor type vinasse polypeptide and application thereof, and belongs to the technical field of polypeptide separation and purification. The method comprises the following steps: S1, pretreatment: drying and crushing soy sauce flavor type vinasse, then treating by adopting a pulsed electric field cooperating with cellulase and Tween, setting the intensity of the pulsed electric field to be 1.0-1.5 kV / cm, adjusting the pulse width to be 10-20ms, keeping the frequency to be 10-15Hz, and controlling the temperature to be 20-30 DEG C; the addition amount of the cellulase is controlled to be 50-80 U / g of dry weight of the vinasse, the treatment time is 2-3 h, and meanwhile low-concentration Tween is added; s2, carrying out composite enzymolysis; s3, gradient membrane separation; and S4, dynamic ion exchange chromatography. Through cooperation of multiple physical-biological-chemical technologies, a complete technical chain for efficient separation and purification of soy sauce flavor type vinasse polypeptide is constructed.

The invention discloses an analysis method and system for energy conservation and loss reduction of transformers, and the method comprises the steps: collecting the standby state data of a transformer group, recognizing a high-loss unit, and predicting the parameter drift trend of the high-loss unit; acquiring an electromagnetic impact strength signal in a working state; the parameter drift trend and the electromagnetic impact strength signal are fused, and the collaborative imbalance risk is evaluated; and according to a risk assessment result and a risk cause, dynamic voltage regulation and load balancing optimization are adaptively executed. The cross-working-condition correlation analysis and closed-loop control are carried out on the transformer group serving as the power supply core, so that the standby no-load loss can be effectively reduced, the equipment aging can be delayed, the operation cost can be reduced, the long-term stability and reliability of the power supply system can be ensured, and the method can be widely applied to the industrial fields of pulsed electric fields, precision manufacturing and the like.

The invention relates to the technical field of hygienic product manufacturing, and discloses a sanitary napkin core body based on a nano material, functional particles are accurately positioned through flow field directional regulation and control of fiber three-dimensional orientation distribution, pulsed electric field activation free radical gradient polymerization and supercritical CO2 deposition, a surface micropore compact water locking layer with the aperture of 5-20 microns is constructed, and an inner macropore flow guide layer is formed. The pore diameter is 80-150 microns, and a cross-scale synergistic structure is formed. Self-reconstruction of the fiber is excited by sudden change of the flow field rotating speed, and mutual exclusion limitation of the absorption rate and the liquid retention amount of a traditional homogeneous structure is broken through in combination with diffusion kinetics of a terahertz wave resonance reinforced cross-linking agent; a C-O-Ag chemical anchoring point is established by a plasma bonding technology, and the nano-silver particles are physically confined by a graphene oxide sheet layer, so that the problems of particle agglomeration and ion burst release in a traditional spraying process are solved. The dynamic multi-field synergistic process realizes porosity gradient, oriented arrangement of molecular chains and long-acting residence of functional particles, and provides a core solution with high absorptivity, zero reverse osmosis and long-acting bacteriostasis for hygienic products.

A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after, contemporaneously, or for only a portion that the cryo-modality is applied to the target tissue.

The invention belongs to the technical field of bimetal part manufacturing, and particularly relates to a method for preparing aluminum-magnesium bimetal through a pulse electromagnetic composite field and a bimetal product, and the method comprises the following steps that a casting foam model is prepared according to the preset form of a workpiece, and a solid aluminum inlay and the casting foam model are assembled to form a composite model. And embedding the composite model into a sand box. During pouring, a pulsed magnetic field and a pulsed electric field are applied to the composite model in a vacuum environment. And cooling to obtain the aluminum-magnesium bimetal product. The invention further discloses the aluminum-magnesium bimetallic product prepared through the method. The method is suitable for manufacturing aluminum-magnesium bimetal castings with complex shapes, the process is simple, the bimetal interface is easy to control, the bimetal bonding performance is good, the alloy strengthening effect is good, grain refinement is effectively achieved, interface defects are overcome, and the method is suitable for producing various related parts in the fields of automobiles, spaceflight and the like.

The invention relates to a regeneration method of waste concrete and a regenerated building material, and relates to the technical field of building materials.The regeneration method of the waste concrete comprises the following steps that the waste concrete is crushed and screened, and waste concrete particles are obtained; adding the waste concrete particles, a silane coupling agent and ionic liquid into a polyethylene glycol aqueous solution, and stirring and mixing to obtain a first mixture; and alternately and circularly treating the first mixture in an ultrasonic field and a pulsed electric field, and the like. Through an innovative waste concrete regeneration mode of combined treatment of physical modification and chemical modification, not only is the water absorption rate of the obtained recycled aggregate reduced, but also the activity of the obtained recycled aggregate is improved. The modified coconut shell powder and other components are subsequently matched for use, so that the compressive strength, cracking resistance and other comprehensive mechanical properties of the regenerated building material are remarkably improved, and the regenerated building material can meet the use requirements in low-temperature and other severe working environments.

The invention discloses a method for treating halogenated organic matter pollution in water by a Fenton-like system based on a pulsed electric field, which comprises the following steps: pre-adjusting the pH value of halogenated organic matter sewage to be treated to 5-8, then adding green rust, introducing pulse current after the system reaches a stable state, adding glucose and glucose oxidase in a stirring state to initiate a Fenton-like reaction, and carrying out a Fenton-like reaction to obtain a Fenton-like reaction solution; the treatment of halogenated organic pollution in water is realized; wherein the current density ranges from 75 mA / cm < 2 > to 125 mA / cm < 2 >, and the current density is increased in a gradient mode every 20-40 min. According to the invention, to-be-treated halogenated organic matter sewage is used as an electrolyte, under the influence of a pulsed electric field, a water body is electrolyzed by using current to generate ClO <-> with high oxidation performance for cooperative treatment, and low-potential Fe in the sewage and C generated by oxidizing glucose generate potential difference to form infinite tiny primary batteries, so that electrode reaction is generated; meanwhile, the pulsed electric field can improve more catalytic sites of glucose oxidase for a patina / glucose-glucose oxidase system, so that the overall catalytic effect is improved, and stable treatment of halogenated organic matter sewage is realized.

The invention discloses a pulse ablation device, a pulse ablation system and a control method.The pulse ablation device comprises an energy transmission assembly and an operation assembly, the energy transmission assembly is connected with the operation assembly, the energy transmission assembly comprises a tubular electrode assembly, and the tubular electrode assembly comprises a first tubular electrode and a second tubular electrode; the first tubular electrode and the second tubular electrode are both connected with the operation assembly, the first tubular electrode and the second tubular electrode are coaxially arranged, and the first tubular electrode and the second tubular electrode are electrically connected; the first tubular electrode comprises a first energy transmission interface, the second tubular electrode comprises a second energy transmission interface, and the first energy transmission interface is electrically connected with the second energy transmission interface; a sensing assembly is arranged in the first tubular electrode and / or the second tubular electrode in an insulating mode, and the sensing assembly comprises a position collecting device. By means of the pulse ablation device, pulse electric field energy can be effectively transmitted, the accuracy and stability of interventional ablation are improved, and the ablation effect is improved.

The invention relates to the technical field of catheter mapping and ablation, and discloses a pulsed electric field ablation control device. The pulsed electric field ablation control device comprises: an impedance detection part for performing fine impedance detection on a contacted tissue by using an electrode on an ablation catheter; the tissue thickness determining part is used for determining the thickness of the tissue according to the change of the detected impedance under different contact conditions; and the ablation control part is used for controlling the ablation catheter to carry out pulsed electric field ablation output according to the determined thickness of the tissue. According to the focusing electrode, the impedance of the contact tissue and the tiny impedance change under different contact conditions can be accurately detected, so that the tissue thickness can be calculated, proper ablation parameters can be matched, and complications caused by too large ablation parameters are avoided. In addition, according to the pulse electric field ablation control technology, the ablation depth can be determined, and excessive ablation is avoided.