427 results about "Pulse electric field" patented technology

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

The invention discloses a novel electrolytic tank pipeline filter and a self-cleaning system. The novel electrolytic tank pipeline filter comprises a multi-stage filtering part, the self-cleaning system and an intelligent control system, the multi-stage filtering part comprises multi-stage filter elements arranged in the material pipeline, and the multi-stage filter elements are arranged from large to small according to the filtering particle size to form a filtering gradient; the self-cleaning system acts on the multi-stage filter element part at the same time or in a time-sharing manner on the basis of a fluid reverse recoil principle; the self-cleaning system is combined with pulsating flushing control, so that the filter element is separated from a filter cake at low loss; the multi-stage gradient filtration is adopted, impurities are efficiently and accurately intercepted, the filter elements with the particle sizes from large to small are arranged in a gradient mode, the first-stage titanium alloy filter element intercepts large particles, the second-stage polytetrafluoroethylene membrane filters tiny impurities, the efficiency is improved through graded interception, the loss of the filter elements is reduced, and the material purity and the hydrogen production quality are guaranteed. The multi-element self-cleaning technology is adopted, low-loss deep cleaning is achieved, and the self-cleaning system integrates multiple technologies such as fluid reverse backflushing, pulsating flushing, ultrasonic vibration and a pulsed electric field.

The invention relates to the technical field of pulse electric field measurement, and discloses a time drift compensation method of a pulse electric field measurement system based on model parameterization. According to the method, a parameterized model is constructed in simulation software, and the parameterized model is additionally provided with two servo zeroing compensation circuits on the basis of an original measurement system, and the two servo zeroing compensation circuits are connected to the output ends of two in-phase operational amplification circuits respectively to form a negative feedback loop used for dynamically suppressing low-frequency baseline drift; acquiring electric field time domain waveform data of the output end of the third in-phase operational amplifier circuit; calculating a transfer function of a pulsed electric field measurement system in the parameterized model, converting the transfer function from a frequency domain state to a time domain state through inverse Fourier transform, and then performing deconvolution on the transfer function of the time domain state and electric field time domain waveform data to obtain real electric field intensity; according to the invention, time drift caused by operational amplifier input imbalance, power supply fluctuation and temperature change is automatically compensated in real time, and the stability and precision of system measurement are improved.

The invention provides a duodenal mucosa adjusting system and method based on pulsed electric field ablation and application of the duodenal mucosa adjusting system and method in diabetes treatment, the duodenal mucosa adjusting system comprises an intelligent control host capable of achieving bidirectional data transmission and an adjustable catheter, and the intelligent control host initializes parameters and adjusts pulse parameters by monitoring impedance data in real time until pulses are interrupted or terminated; periodic ablation is carried out, periodic intervals are used for measuring impedance data, the ablation depth is evaluated according to the impedance change rate, and whether next section ablation is carried out or not is judged till full-area ablation is completed. The far-end ablation adopts a structure of combining fusiform flexible support and annular electrode spiral arrangement to ensure that an ablation field uniformly covers mucous membrane plica of a duodenum bulb part and a descending part; a cell selective ablation mechanism is adopted, the critical electric field intensity is set, K cell electroporation is selectively induced, and meanwhile goblet cells are protected.

A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after, contemporaneously, or for only a portion that the cryo-modality is applied to the target tissue.

The invention belongs to the technical field of bimetal part manufacturing, and particularly relates to a method for preparing aluminum-magnesium bimetal through a pulse electromagnetic composite field and a bimetal product, and the method comprises the following steps that a casting foam model is prepared according to the preset form of a workpiece, and a solid aluminum inlay and the casting foam model are assembled to form a composite model. And embedding the composite model into a sand box. During pouring, a pulsed magnetic field and a pulsed electric field are applied to the composite model in a vacuum environment. And cooling to obtain the aluminum-magnesium bimetal product. The invention further discloses the aluminum-magnesium bimetallic product prepared through the method. The method is suitable for manufacturing aluminum-magnesium bimetal castings with complex shapes, the process is simple, the bimetal interface is easy to control, the bimetal bonding performance is good, the alloy strengthening effect is good, grain refinement is effectively achieved, interface defects are overcome, and the method is suitable for producing various related parts in the fields of automobiles, spaceflight and the like.

The invention provides signal acquisition equipment for pulsed electric field ablation. The signal acquisition equipment comprises an input interface module, a signal conditioning circuit, a differential-to-single-ended circuit and a signal acquisition module, the input interface module comprises a first input interface and a second input interface; the signal conditioning circuit is arranged between the input interface module and the differential-to-single-ended circuit and comprises an adjustable resistance sub-circuit with an adjustable resistance value, a first end of the adjustable resistance sub-circuit is connected with the first input interface, a second end of the adjustable resistance sub-circuit is connected with the second input interface, and a sliding end of an adjustable resistor in the adjustable resistance sub-circuit is grounded; the first input end of the differential-to-single-end circuit is connected with the first end of the adjustable resistor sub-circuit, and the second input end of the differential-to-single-end circuit is connected with the second end of the adjustable resistor sub-circuit; and the signal acquisition module is connected with the output end of the differential-to-single-terminal circuit. According to the signal acquisition equipment provided by the embodiment of the invention, the accuracy of pulse signal acquisition can be improved.

The invention relates to the technical field of TGV packaging, in particular to an electroplating system for a TGV and panel-level packaging process. Comprising a tank body and environment maintenance module, a soluble anode and current redistribution module, a cathode clamp and substrate posture regulation and control module, a micro-area jet flow coupling array module, a pulsed electric field and impedance compensation module and an electroplating liquid peripheral circulation and online regeneration module, the thickness uniformity of a plating layer on a panel-level large-size substrate is remarkably improved through real-time closed-loop coupling of micro-area jet flow and current density and accurate correction of an adjustable shielding grid on edge current, the thickness uniformity of the plating layer on the panel-level large-size substrate is improved, and the thickness uniformity of the plating layer on the panel-level large-size substrate is improved. According to the method, the through hole filling void rate is reduced to an extremely low level, and bubble desorption, crystal nucleus homogenization and updating of an interface solution are effectively promoted by utilizing micro-vibration, dynamic variable immersion and periodic shaking functions of the cathode clamp, so that thickening of a diffusion layer is inhibited, and the defects of through hole filling void and the like are reduced.

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

The invention discloses a composite electric field catalytic oxidation synergistic oil and gas field produced water treatment method which comprises the following steps: acquiring an electric flocculation effect generated by a corrosion-resistant titanium-based coating anode and a stainless steel cathode under optimized pulsed electric field parameters through a turbidity sensor and a particle size analyzer, and superposing low-frequency pulses in a composite pulse mode, maintaining the temperature of the reactor to be 20-40 DEG C in combination with a temperature control system to obtain initial floc particle size distribution and concentration data; the concentration state of the floc in the concentration tank is monitored by adopting a conductivity sensor according to the amount of the floc in the concentration tank treatment pollution discharge scheduling scheme, the content of remaining oil drops and suspended solids is analyzed in combination with an emulsion monitoring module, and the water quality parameter change of the concentration tank is recorded through a data analysis system, so that a final water quality treatment result is determined.

Systems, devices, and methods described herein relate to catheter devices for therapy delivery. In some embodiments, a catheter device includes an expandable electrode and a needle, where the needle can be advanced distal to a distal end of the expandable electrode and inserted into a tissue site. The expandable electrode and the distal end of the needle can be configured to deliver electroporation to the tissue site.

The invention provides a microwave pulse electric field vibration synergistic fracturing and permeability increasing gas extraction promoting device and method, and relates to the technical field of low-permeability coal seam fracturing and permeability increasing. According to the method, multi-physical field coupling synergistic interaction is achieved, and the fracturing efficiency and range are greatly improved. According to the invention, deep collaboration of multiple physical fields is realized through a specific time sequence and energy ratio. The thermal stress generated by microwave preheating enables a large number of microcracks to be generated in the coal body and soften the coal quality, and the resistivity and the medium strength of the coal body are reduced. In the state, the pulsed electric field with lower voltage can preferentially and effectively break down and expand the fracture network along the micro-fracture path; meanwhile, high-frequency mechanical vibration not only efficiently transmits energy to the tip of the fracture to generate stress concentration to promote extension of the fracture, but also disturbs coal particles to promote gas desorption. Through three-field cooperation, cracks can be more efficiently initiated, expanded and communicated in a three-dimensional space, a three-dimensional complex crack network far beyond the action range of a single technology is formed, and the overall permeability of a coal seam is remarkably improved.

The invention belongs to the technical field of fruit freeze-drying processing, and particularly relates to a comprehensive fruit freeze-drying processing method capable of reducing nutrient loss of fruits, which comprises the following steps: S1, immersing sliced fruit slices into a composite color fixative, and simultaneously applying ultrasonic and pulsed electric field treatment on the composite color fixative system containing the fruit slices under the conditions that the ultrasonic power is 200-300W, the pulsed electric field intensity is 15-25kV / cm, and the ultrasonic power is 200-300W and the pulsed electric field intensity is 15-25kV / cm; the co-processing time is 2-4 minutes, so as to obtain the color-protected and strengthened fruit slices; s2, sequentially carrying out three-stage magnetic field freezing treatment on the color-protected and strengthened fruit slices to obtain frozen fruit slices; s3, dynamically adjusting parameters of the frozen fruit slices by adopting an AI algorithm, and performing vacuum freeze-drying in stages to obtain primary freeze-dried fruit slices; s4, placing the primary freeze-dried fruit slices in a vacuum environment to obtain deeply dried fruit slices; and S5, soaking the deeply dried fruit slices in an aqueous solution containing 0.5-1% of amyloid-like protein, 0.2-0.4% of sodium alginate and 0.1-0.3% of cellulose nanocrystals for 1-2 minutes to form a composite protective film with the thickness of 1-3 microns, so as to obtain the coated fruit slices.

The invention discloses a coarse cereal food processing method based on biological enzyme-physical field coupling, and belongs to the technical field of coarse cereal food processing and utilization. The preparation method comprises the following steps: firstly, mixing pure coarse cereal powder with a compound modified material, and premixing to obtain a premix; adding deionized water, a compound flavourzyme solution and carboxymethyl chitosan into the premix for enzymolysis, performing ultrasonic and pulsed electric field cooperative treatment after enzymolysis is finished, performing vacuum concentration after treatment, adding trehalose and modified diatomite, and uniformly mixing to obtain a coupling modified material; then kneading dough, adding food-grade glycerol during dough kneading, rolling, and cutting into strips to obtain noodle blanks; and finally, carrying out gradient drying on the noodle blanks, introducing nitrogen in the drying process, and obtaining the brewing instant coarse cereal noodles after the drying is finished. The method effectively solves the problems of non-uniform rehydration, unstable forming, high storage embrittlement rate, turbid soup and the like of the brewing instant coarse cereal noodles, and meets the industrial production requirements of the brewing instant coarse cereal noodles.

The invention relates to the technical field of food processing and functional beverages, in particular to a preparation technology of wheat germ pulp, the wheat germ pulp and a functional beverage containing the wheat germ pulp. According to the preparation process of the wheat germ pulp provided by the invention, the pulsed electric field is applied in the gelatinization process, a specific enzymolysis sequence of amylase, saccharifying enzyme and cellulase is adopted, and ultrasonic treatment is carried out during first enzymolysis, so that the sugar degree and yield of the wheat germ pulp are remarkably improved, and meanwhile, the pulp viscosity is reduced; the taste of the wheat germ pulp is effectively improved.

The application discloses a kind of continuous high-voltage pulse electric field processing berry functional active ingredient reinforced extraction method.The method comprises the following steps: after the cooling device is cooled to reach the set temperature by the processing chamber device, set high-voltage pulse power output parameter, high-voltage pulse power generates bipolar symmetric square wave, set pulse electric field parameter, the distance of two titanium alloy electrodes is 100mm, the pretreated berry material is transported to the processing chamber body, and the high-voltage pulse electric field processing is carried out on the berry material, to obtain the berry extract containing active ingredient.The method proposed in the application uses continuous round square corrosion-resistant pulse electric field processing chamber, the overall structure is convenient to assemble and process, the processing chamber can be increased according to actual needs, and synchronous cooling can be realized at the same time, the low-temperature extraction and active protection of functional active ingredient are realized while the electrode is protected.

The present application is applicable to the technical field of pulsed electric field ablation catheters, and provides a pulsed electric field ablation catheter. The pulsed electric field ablation catheter comprises: a tube body part and an expansion part. The tube body part comprises a main body tube and a push-pull tube, and the push-pull tube movably penetrates through the main body tube and at least partially extends out from a distal end of the main body tube. The expansion part comprises an expansion tube, and a plurality of branch tubes are formed between a proximal end and a distal end of the expansion tube. At least one treatment electrode is provided on the branch tube, and a cooling gap in communication with the external environment is provided between the branch tube and the treatment electrode. A first perfusion channel is provided on the main body tube, and a second perfusion channel is provided on the branch tube. The first perfusion channel is in communication with the second perfusion channel, and the second perfusion channel is in communication with the cooling gap. The pulsed electric field ablation catheter provided by the present application does not require a perfusion hole to be formed on the surface of the treatment electrode, which can effectively avoid the phenomenon of spark discharge on the treatment electrode, offering high reliability.

The invention relates to the technical field of nanotechnology, and discloses a high-concentration nitrogen nanobubble generation method based on multi-mechanism synergy, which comprises the following steps of: simultaneously applying a multi-stage vortex for generating turbulent flow and shearing force and periodically pressurizing and depressurizing the inside of a cavity to a water sample of supersaturated dissolved nitrogen flowing into the cavity, and in the process of reducing the pressure in the cavity, a pulse electric field which is synchronous with the frequency and the phase of the periodic pressure increasing and reducing is applied, and coalescence between interfaces of the continuously generated initial nanobubbles is inhibited through the pulse electric field. A pressure oscillation cavity of the device is provided with a water sample input port and a target concentration nitrogen nanobubble water sample output port, a multi-stage eddy current system for generating turbulent flow is fixedly arranged in the cavity, a pressure adjusting system capable of forming periodic pressure oscillation is communicated with the outside of the cavity, and an electric field generating system containing a relative electrode and a pulse power supply is arranged in the cavity. And the self-adaptive control unit monitors the pressure oscillation frequency and phase in real time and controls the pulse power supply to output a synchronous pulse electric field in a voltage reduction stage.

The invention relates to a lithium ion battery repairing technology, in particular to an electrochemical regeneration method after capacity fading of a lithium iron phosphate battery (LiFePO). In order to overcome the defects in the prior art, the invention provides a disassembly-free and zero-cost lossless in-situ repair method based on deep pulse discharge. Aiming at the defects of complex disassembly operation, low repair efficiency and uncontrollable growth of lithium dendrites in the existing lithium ion battery repair technology, the method dynamically adjusts the lithium ion concentration gradient in a pulse intermittent period by applying a specific pulse technology and utilizing a pulse discharge-relaxation coordinated regulation mechanism, inhibits dendritic crystal growth caused by local lithium deposition, and improves the repair efficiency of the lithium ion battery. Dead lithium activation is realized, and the lithium ion battery is effectively repaired.

The invention relates to the technical field of medical equipment, and discloses an ablation method for automatically identifying impedance and adjusting an output form, which comprises the following steps: judging the contact state of each electrode pair and tissue by independently monitoring the resistance of each electrode pair and comparing the resistance with a preset threshold value, starting energy output only for the electrode pair which is in effective contact, and starting energy output only for the electrode pair which is in effective contact; therefore, energy is prevented from being released to a non-target region; in the ablation process, the real-time resistance change of the effective electrode pair is continuously tracked, when it is monitored that a preset characteristic inflection point appears on a resistance change curve, the system judges that the point reaches an ideal ablation end point, energy output of the path is independently stopped, excessive ablation is prevented, and in order to guarantee the measurement precision, the system can be used for monitoring the ablation time. Resistance monitoring and pulse electric field output adopt a time division multiplexing technology, and interference of a strong electric field on measurement is avoided. Accurate and independent contact ablation stop closed-loop control is achieved for each ablation target, and the safety and effectiveness of an operation are remarkably improved.

A near-atomic-scale electrolytic machining method based on an interface self-assembly biomask comprises the steps that firstly, hydroxylation pretreatment is conducted on the surface of an anode of a workpiece, then the surface of the anode is covered with an organic solvent phase containing phospholipid monomers, water-phase electrolyte drops are introduced, molecular self-assembly driving force at an oil-water-metal three-phase interface is utilized, and the surface of the anode of the workpiece is subjected to near-atomic-scale electrochemical machining. And rapidly forming a layer of ultrathin, continuous and stable support phospholipid bilayer mask on the surface of the workpiece in situ. Then, biological nanochannels are embedded in the biomimetic mask to construct a confinement ion transport path. And finally, a precise pulse electric field is applied, electrolyte ions are driven to be strictly limited in the nanometer channel and transmitted to the surface of the workpiece, local anodic dissolution is triggered, and therefore localized material removal of the nanometer scale or even the near-atomic scale is achieved. According to the method, the technical bottleneck that the high-quality phospholipid bilayer is difficult to prepare on the high-surface-energy metal surface is solved, and a new way is provided for ultra-precision electrolytic machining.

Devices, systems and methods are provided for treating target tissue with pulsed electric field energy in a manner that does not induce cardiac arrhythmias such as fibrillation of the heart and therefore negates any need for cardiac synchronization of energy delivery. Cardiac synchronization is typically employed to avoid delivering energy during portions of the cardiac cycle that are vulnerable to inducing fibrillation. Thus, herein parameters are manipulated to reduce the probability of inducing an arrhythmia. Typically, high voltage energy can trigger a premature action potential within the cardiac muscle as the delivered energy increases the cardiac muscle cell membrane permeability allowing ion transport, which can induce cardiac arrhythmias, especially ventricular fibrillation. However, both shorter pulse durations (i.e. higher frequencies such as 100-600 kHz) and biphasic waveform shapes theoretically and practically reduce the probability of inducing an arrhythmia.

The invention belongs to the technical field of preparation of nano silicon materials, and particularly relates to a method for preparing nano silicon by etching a silicon-aluminum alloy and a nano silicon material thereof. Comprising the following steps: placing a pretreated silicon-aluminum alloy sample wafer in an etching tank containing a main etching solution, etching under the action of an alternating pulse electric field and ultrasonic-megasonic coupling, and adjusting the pH value to 2.5-3.0 by using acetic acid; quickly washing the silicon-aluminum alloy sample wafer subjected to main etching, putting the silicon-aluminum alloy sample wafer into an electrolytic cell containing a composite buffer solution of oxalic acid and sulfuric acid, and performing electrochemical fine etching under a direct-current constant-voltage electric field; and when the etching current density is reduced to 10% of the initial value, the reaction is terminated, and after low-temperature treatment and low-temperature vacuum drying, the nano silicon material with the residual Al content of 8-12 wt% and the O / Si atomic ratio of 0.15-0.25 is obtained. According to the invention, the problems of out-of-control components, structural damage and serious pollution in the prior art are solved, and the nano silicon material with controllable residual aluminum element and low oxygen-silica ratio can be stably prepared.

According to the emblic leafflower fruit and green plum composite fruit juice with the anti-oxidation effect and the preparation method thereof, emblic leafflower fruit juice prepared at low temperature after being pretreated by a non-thermal processing technology pulsed electric field is innovatively and reasonably matched with green plum fruit juice raw materials, and the acidity adjusting and aroma enhancing effects of the green plum juice are combined; the astringent taste is reduced through the acid-base complexing effect while more nutritional ingredients are reserved, the delicate flavor of the compound fruit juice is increased through a certain synergistic effect between the green plum juice and the emblic leafflower fruit juice, the astringent taste of the emblic leafflower fruit juice and the sour taste of the green plum juice can be well matched under a certain proportion, and the compound fruit juice is sour, sweet and palatable and has a good taste. The phyllanthus emblica fruit juice prepared by the method has the advantages that the taste of the phyllanthus emblica fruit juice is obviously better than that of compound juice of single juice, and the phyllanthus emblica fruit juice has high antioxidant activity, can be applied to the fields of functional beverages, food supplements and beauty and health care, and solves the problems of serious product homogenization and poor taste in traditional phyllanthus emblica fruit juice processing.

This invention belongs to the field of grain deep processing technology and discloses a method for reducing the glycemic index (GI) of brown rice flour through a combination of thermal and non-thermal physical processing. The method involves: pulverizing high-quality brown rice and allowing it to stand in equilibrium with water; subjecting the material to low-temperature wet heat treatment at a moisture content of 30%–50%; baking the wet-heat treated material; mixing the baked material with pure water and performing a first freeze-thaw cycle; subjecting the mixture to intermittent pulsed electric field treatment in a multi-cycle intermittent manner; subjecting the pulsed electric field treated material to a second freeze-thaw cycle; and finally centrifuging, drying, sieving, and packaging the material. This method regulates the starch structure to obtain a low glycemic index product through the synergistic effect of a specific sequence of thermal and non-thermal treatments. This invention innovatively designs a two-stage freeze-thaw cycle process before and after the pulsed electric field treatment, employing physical modification methods throughout the process to ensure product safety. It has low equipment requirements and broad industrial application prospects.

The invention discloses a device for noninvasive regulation and control of a blood brain barrier in a non-invasive pulsed electric field. The device comprises a high-voltage pulse generator, a plurality of treatment electrodes and a fixing device. The connection tightness of endothelial cells is adjusted through a high-voltage short-pulse electric field, local regulation and control of the brain area are achieved in combination with electrode design, pulse parameters are flexibly adjusted to balance the effect and damage, and a new non-invasive physical treatment means is provided for assisting drug cross-blood-brain-barrier delivery. Compared with focused ultrasound, the multi-mechanism synergistic effect (electroporation effect and bioelectrochemical effect) is utilized instead of depending on the mechanical effect of exogenous microbubbles, so that the safety risk is remarkably reduced. The system has the advantages of noninvasiveness, safety and space flexibility, and can be opened for a long time. The non-invasive electrode is used for delivering instantaneous high-voltage electric pulses, which is different from conventional low-voltage long-time electric stimulation.

The invention provides a fermentation device based on multi-physical field coordination and application thereof. The fermentation device comprises a fermentation tank unit, an annular magnetic field generation unit, a pulsed electric field generation unit and a control unit. The stable and energy-free background magnetic field is provided through the permanent magnet array, the background magnetic field and the pulsed electric field form synergy, the metabolism efficiency of microorganisms is remarkably improved, the operation cost is low, the device structure is simple, the device can be flexibly deployed, and the device is suitable for large-scale deployment and transformation on an industrial fermentation tank needing long-term and stable operation; a static background magnetic field generated by the permanent magnet is highly stable, is not influenced by fluctuation of a power grid, and is mutually independent and non-interfering with the distribution of a pulse electric field, so that the reliability and repeatability of the process are ensured.

Embodiments of the present application provide a duodenum-based electric field ablation method, system and device, the method comprising: in the case of determining a target tissue corresponding to a target object, determining the narrow pulse parameters required by the target tissue; wherein the target tissue is the position of the target object's duodenum that needs to be subjected to pulse electric field ablation; determining the state information of the main control system; detecting the state information, and in the case that the state information meets the preset condition, generating a first pulse and a second pulse based on the narrow pulse parameters through the driving of the H-bridge circuit; wherein the preset condition is that the state information of the main control system meets the preset state; performing phase shift control processing based on the first pulse and the second pulse to determine the narrow pulse corresponding to the narrow pulse parameters; and achieving electric field ablation of the target tissue through multiple electrodes based on the narrow pulse. In the above scheme, the stability of the output of the narrow pulse is improved, thereby improving the electric field ablation effect on the duodenum.

Described here are devices, systems, and methods for treating tissue. In some variations, a method of treating a target tissue may comprise advancing a tissue treatment system and a visualization device to the target tissue of a patient. The tissue treatment system may comprise a tissue treatment device comprising an elongate body, an expandable member including an electrode array, and a sheath. In a delivery configuration, the expandable member may be disposed in the sheath circumferentially about the visualization device in an unexpanded configuration. The expandable member may be advanced distal to the sheath. The expandable member may be transitioned into an expanded configuration. The target tissue may be treated using the tissue treatment device. The expandable member may be retracted to reposition the system to the delivery configuration.