743 results about "Pulse electric field" patented technology

The invention discloses a flocculation treatment device and method for removing high turbidity of a water sample. The method comprises the following steps: monitoring an inflow turbidity parameter in real time, continuously collecting original optical characteristic data of water through an optical sensor array, and calculating a turbidity fluctuation rate parameter after noise reduction treatment; carrying out graded rotational flow mixing treatment, forming a pressure gradient through three stages of tapered rotational flow pipes in sequence, activating an ultrasonic frequency field, and synchronously adding main and auxiliary flocculants; the method comprises the following steps: introducing a water sample into a multi-stage gradient flocculation reaction zone, and sequentially executing turbulent flow enhanced flocculation, slow stirring flocculation and pulsed electric field assisted flocculation to form a floc structure with different particle size distribution; running parameters of a sedimentation module are adjusted according to real-time effluent turbidity feedback, and the inclination angle of an inclined plate assembly and the opening degree of a mud discharging valve are dynamically adjusted; a parameter set is updated through a prediction model based on periodically collected system operation data, a closed-loop optimization control strategy is formed, the adaptability to extreme turbidity is enhanced, the solid-liquid separation efficiency is improved, the overall energy consumption is reduced, and the efficient and stable requirements of emergency treatment are met.

The invention belongs to the field of blood product separation, and discloses a high-efficiency chromatography system and method for blood product separation, and the system comprises an intelligent chromatography column module, an automatic sample injection and accurate flow rate control module, a chromatography filler and column design module, a real-time detection and data analysis module, and an intelligent automatic control and management module. By designing an efficient micro-nano filler chromatographic column and matching with a pulsed electric field auxiliary technology and intelligent automatic control, efficient and high-purity separation and purification of target blood product components are realized. The intelligent regulation and control module used in the invention can dynamically regulate chromatography conditions in real time, and the problems of unstable flow velocity and column pressure in the traditional method are thoroughly solved. And meanwhile, a multi-point real-time detection and feedback technology is adopted, so that the separation process is more accurate, transparent and controllable.

The invention relates to a kitchen waste oil recovery treatment method, which comprises: S1, carrying out multi-field synergistic pretreatment: sequentially carrying out ultrasonic wave and high-frequency pulse electric field treatment on waste oil to break an emulsion layer, adding magnetic nanoparticles to adsorb polar impurities, and carrying out magnetic field separation to obtain high-purity oil; s2, supercritical catalytic reaction: under the CO2 supercritical condition, using a core-shell structure composite catalyst to synchronously perform transesterification reaction and glycerol dehydration reaction; s3, dynamic membrane separation: separating biodiesel and glycerol in real time through an intelligent membrane assembly; s4, gradient utilization of energy: recovering reaction waste heat to drive membrane distillation to concentrate wastewater, and using tail gas CO2 for carbonation reaction to generate calcium carbonate. Through four core technologies of multi-field collaborative pretreatment, low-temperature supercritical catalysis, dynamic membrane separation and energy gradient utilization, triple limitations on efficiency, cost and environmental protection in the prior art are remarkably broken through.

Treatment of damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) is provided by delivering specialized pulsed electric field energy to target tissue areas in a specific dose so as to obtain a superior outcome. The specialized PEF energy and delivery has been optimized to provide advanced treatment of target tissue areas, including destruction of undesired tissue and generation of improved inflammatory and immune responses. The specialized PEF energy provides superior outcomes to radiofrequency ablation and irreversible electroporation.

High-frequency irreversible electroporation (H-FIRE) is a tissue ablation modality employing bursts of electrical pulses in a positive phase-interphase delay-negative phase-interpulse delay pattern. Despite accumulating evidence suggesting the significance of these delays, their effects on therapeutic outcomes from clinically-relevant H-FIRE waveforms have not been studied extensively. The present invention provides methods of pulse delivery, including delays, that mitigate bubble formation and / or minimize the risk of arcing, such as due to the presence of bubbles, and / or minimize muscle stimulation are described herein.

The invention discloses an electro-optical-acoustic cooperative partial discharge detection device and method, and belongs to the field of equipment discharge fault detection. The device integrates a high-frequency current detection module, a photoelectric coupling detection module and an acoustic emission detection module; a high-frequency pulse current signal of a cable grounding loop, a pulse electric field of an insulating surface and an ultrasonic signal in a solid medium can be collected at the same time; all the collected signals are sent to the signal integrated processing module for alignment, noise reduction and multi-signal homologous conformity test; after detection, the signal integration processing module extracts combined feature vectors from the signals and inputs the combined feature vectors to the classification discriminator; finally, the discriminator outputs the probability of partial discharge, and if the probability exceeds a preset threshold value, it is judged that partial discharge exists in the cable. Therefore, by implementing the method and the device, the problems that single-mode detection in the prior art is poor in anti-interference capability in a complex field environment, and false alarm or missing alarm is easy to occur can be solved.

Systems, devices, and methods described herein relate to catheter devices for therapy delivery. In some embodiments, a catheter device includes an expandable electrode and a needle, where the needle can be advanced distal to a distal end of the expandable electrode and inserted into a tissue site. The expandable electrode and the distal end of the needle can be configured to deliver electroporation to the tissue site.

The invention discloses a method for preparing ultra-high-purity quartz by multi-stage synergistic purification of quartz ore, and belongs to the technical field of ultra-high-purity quartz preparation. According to the method, natural quartz ore is used as a raw material, mineral impurities, lattice impurities and inclusions in quartz are deeply removed through multi-stage synergistic processes such as low-temperature plasma activation, biological leaching, supercritical CO2-assisted acid leaching, microwave-assisted chloridizing roasting and pulsed electric field enhanced acid leaching, and finally a high-purity quartz product with the SiO2 purity larger than or equal to 99.998% (4N8 grade) is obtained. According to the invention, a low-temperature plasma activation technology, microbial metallurgy, supercritical fluid extraction and a pulsed electric field strengthening technology are organically combined, so that the energy efficiency bottleneck and environmental protection limitation of a traditional high-purity quartz preparation process are broken through; the obtained quartz sand product can reach the standards of high-purity quartz sand for semiconductor quartz glass and high-purity quartz sand for photovoltaic quartz crucibles.

The invention discloses a novel electrolytic tank pipeline filter and a self-cleaning system. The novel electrolytic tank pipeline filter comprises a multi-stage filtering part, the self-cleaning system and an intelligent control system, the multi-stage filtering part comprises multi-stage filter elements arranged in the material pipeline, and the multi-stage filter elements are arranged from large to small according to the filtering particle size to form a filtering gradient; the self-cleaning system acts on the multi-stage filter element part at the same time or in a time-sharing manner on the basis of a fluid reverse recoil principle; the self-cleaning system is combined with pulsating flushing control, so that the filter element is separated from a filter cake at low loss; the multi-stage gradient filtration is adopted, impurities are efficiently and accurately intercepted, the filter elements with the particle sizes from large to small are arranged in a gradient mode, the first-stage titanium alloy filter element intercepts large particles, the second-stage polytetrafluoroethylene membrane filters tiny impurities, the efficiency is improved through graded interception, the loss of the filter elements is reduced, and the material purity and the hydrogen production quality are guaranteed. The multi-element self-cleaning technology is adopted, low-loss deep cleaning is achieved, and the self-cleaning system integrates multiple technologies such as fluid reverse backflushing, pulsating flushing, ultrasonic vibration and a pulsed electric field.

The invention relates to the technical field of pulse electric field measurement, and discloses a time drift compensation method of a pulse electric field measurement system based on model parameterization. According to the method, a parameterized model is constructed in simulation software, and the parameterized model is additionally provided with two servo zeroing compensation circuits on the basis of an original measurement system, and the two servo zeroing compensation circuits are connected to the output ends of two in-phase operational amplification circuits respectively to form a negative feedback loop used for dynamically suppressing low-frequency baseline drift; acquiring electric field time domain waveform data of the output end of the third in-phase operational amplifier circuit; calculating a transfer function of a pulsed electric field measurement system in the parameterized model, converting the transfer function from a frequency domain state to a time domain state through inverse Fourier transform, and then performing deconvolution on the transfer function of the time domain state and electric field time domain waveform data to obtain real electric field intensity; according to the invention, time drift caused by operational amplifier input imbalance, power supply fluctuation and temperature change is automatically compensated in real time, and the stability and precision of system measurement are improved.

The invention provides a duodenal mucosa adjusting system and method based on pulsed electric field ablation and application of the duodenal mucosa adjusting system and method in diabetes treatment, the duodenal mucosa adjusting system comprises an intelligent control host capable of achieving bidirectional data transmission and an adjustable catheter, and the intelligent control host initializes parameters and adjusts pulse parameters by monitoring impedance data in real time until pulses are interrupted or terminated; periodic ablation is carried out, periodic intervals are used for measuring impedance data, the ablation depth is evaluated according to the impedance change rate, and whether next section ablation is carried out or not is judged till full-area ablation is completed. The far-end ablation adopts a structure of combining fusiform flexible support and annular electrode spiral arrangement to ensure that an ablation field uniformly covers mucous membrane plica of a duodenum bulb part and a descending part; a cell selective ablation mechanism is adopted, the critical electric field intensity is set, K cell electroporation is selectively induced, and meanwhile goblet cells are protected.

The invention discloses an irreversible electroporation damage assessment system and method based on myocardial dielectric properties, solves the problem of how to assess damage in a pulsed electric field ablation process, and belongs to the technical field of medical equipment. The system comprises an acquisition module and a workstation, wherein the acquisition module acquires an intracardiac ECG signal, a global electric field voltage signal of a target cardiac cavity, and impedance and temperature between ablation electrode pairs in real time; the work station processes the collected signals to obtain electrocardio characteristics, ablation parameters, temperature between the ablation electrode pairs, impedance drop, contact force and contact state between the ablation electrode pairs and myocardial tissue and ablation electrode position stability, the obtained signals are input into the evaluation model, and the evaluation model outputs IRE injury evaluation classification results. The evaluation model is realized based on a neural network. And real-time measurement and evaluation are carried out on PF ablation injury so as to assist a user to complete comprehensive, objective and accurate evaluation of the ablation effect.

The present invention discloses a method and device for determining ablation parameters for high-frequency pulse electric field ablation. The method comprises: acquiring collected medical image data containing depth information, determining a corresponding lesion box containing three-dimensional information of the lesion based on the medical image data; analyzing and segmenting the lesion box to obtain the contour and depth of the lesion and the contour of the electrode used to ablate the lesion; starting from a plurality of equally spaced points on the boundary of the electrode contour, emitting a preset number of rays to the surrounding area, obtaining the number of intersections between the rays and the lesion box to determine whether the electrode and the lesion are in contact; when the electrode and the lesion are in contact, determining the corresponding ablation parameters based on the contour and depth of the lesion, the ablation parameters including pulse voltage, pulse width, number of pulse trains, and number of discharges. The present invention solves the problem of inaccurate ablation parameter determination in the prior art.

Treatment of damaged, diseased, abnormal, obstructive, cancerous or undesired tissue (e.g. a tumor, a benign tumor, a malignant tumor, a cyst, or an area of diseased tissue, etc) is provided by delivering specialized pulsed electric field (PEF) energy to target tissue areas in a specific dose so as to obtain a superior outcome. The PEF energy and delivery has been optimized to provide advanced treatment of target tissue areas, including destruction of undesired tissue and generation of improved inflammatory and immune responses. These various types of treatment are controlled by a variety of factors including the electrode geometry, the dose of PEF energy delivered, the time the energy is delivered over, and the waveform of the PEF energy itself. The PEF energy is delivered in the form a dose which is considered to be one application of the specialized energy. Each dose creates a lesion in the target tissue area.

The present invention discloses a gradient structure 3D printed metal component and its preparation process, belonging to the field of 3D printing forming preparation. The preparation process of the present invention includes: 1) 3D printing material preparation, 2) 3D model construction and parameter setting, 3) 3D printing forming, 4) mechanical treatment, 5) surface treatment, and finally obtaining a 3D printed metal component with a dense surface without pores and excellent mechanical properties. The present invention solves the problems of material surface densification and pores by introducing laser peening technology into the preparation process of 3D printed metal components, and solves the problem of crack propagation by introducing a pulsed electric field during the laser peening process, thereby preparing high-quality gradient structure 3D printed metal components.

The invention discloses a separation and purification method of soy sauce flavor type vinasse polypeptide and application thereof, and belongs to the technical field of polypeptide separation and purification. The method comprises the following steps: S1, pretreatment: drying and crushing soy sauce flavor type vinasse, then treating by adopting a pulsed electric field cooperating with cellulase and Tween, setting the intensity of the pulsed electric field to be 1.0-1.5 kV / cm, adjusting the pulse width to be 10-20ms, keeping the frequency to be 10-15Hz, and controlling the temperature to be 20-30 DEG C; the addition amount of the cellulase is controlled to be 50-80 U / g of dry weight of the vinasse, the treatment time is 2-3 h, and meanwhile low-concentration Tween is added; s2, carrying out composite enzymolysis; s3, gradient membrane separation; and S4, dynamic ion exchange chromatography. Through cooperation of multiple physical-biological-chemical technologies, a complete technical chain for efficient separation and purification of soy sauce flavor type vinasse polypeptide is constructed.

The invention discloses an analysis method and system for energy conservation and loss reduction of transformers, and the method comprises the steps: collecting the standby state data of a transformer group, recognizing a high-loss unit, and predicting the parameter drift trend of the high-loss unit; acquiring an electromagnetic impact strength signal in a working state; the parameter drift trend and the electromagnetic impact strength signal are fused, and the collaborative imbalance risk is evaluated; and according to a risk assessment result and a risk cause, dynamic voltage regulation and load balancing optimization are adaptively executed. The cross-working-condition correlation analysis and closed-loop control are carried out on the transformer group serving as the power supply core, so that the standby no-load loss can be effectively reduced, the equipment aging can be delayed, the operation cost can be reduced, the long-term stability and reliability of the power supply system can be ensured, and the method can be widely applied to the industrial fields of pulsed electric fields, precision manufacturing and the like.

The invention relates to the technical field of hygienic product manufacturing, and discloses a sanitary napkin core body based on a nano material, functional particles are accurately positioned through flow field directional regulation and control of fiber three-dimensional orientation distribution, pulsed electric field activation free radical gradient polymerization and supercritical CO2 deposition, a surface micropore compact water locking layer with the aperture of 5-20 microns is constructed, and an inner macropore flow guide layer is formed. The pore diameter is 80-150 microns, and a cross-scale synergistic structure is formed. Self-reconstruction of the fiber is excited by sudden change of the flow field rotating speed, and mutual exclusion limitation of the absorption rate and the liquid retention amount of a traditional homogeneous structure is broken through in combination with diffusion kinetics of a terahertz wave resonance reinforced cross-linking agent; a C-O-Ag chemical anchoring point is established by a plasma bonding technology, and the nano-silver particles are physically confined by a graphene oxide sheet layer, so that the problems of particle agglomeration and ion burst release in a traditional spraying process are solved. The dynamic multi-field synergistic process realizes porosity gradient, oriented arrangement of molecular chains and long-acting residence of functional particles, and provides a core solution with high absorptivity, zero reverse osmosis and long-acting bacteriostasis for hygienic products.

A multimodality or hybrid ablation system includes an ablation apparatus for creating a lesion in target tissue. The ablation apparatus has an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material. A plurality of electrodes are arranged on the ablation portion for measuring or verifying tissue contact with the tissue and applying a pulsed electric field. Optionally, the pulsed electric field may be applied after, contemporaneously, or for only a portion that the cryo-modality is applied to the target tissue.

The invention belongs to the technical field of bimetal part manufacturing, and particularly relates to a method for preparing aluminum-magnesium bimetal through a pulse electromagnetic composite field and a bimetal product, and the method comprises the following steps that a casting foam model is prepared according to the preset form of a workpiece, and a solid aluminum inlay and the casting foam model are assembled to form a composite model. And embedding the composite model into a sand box. During pouring, a pulsed magnetic field and a pulsed electric field are applied to the composite model in a vacuum environment. And cooling to obtain the aluminum-magnesium bimetal product. The invention further discloses the aluminum-magnesium bimetallic product prepared through the method. The method is suitable for manufacturing aluminum-magnesium bimetal castings with complex shapes, the process is simple, the bimetal interface is easy to control, the bimetal bonding performance is good, the alloy strengthening effect is good, grain refinement is effectively achieved, interface defects are overcome, and the method is suitable for producing various related parts in the fields of automobiles, spaceflight and the like.

The invention relates to the technical field of catheter mapping and ablation, and discloses a pulsed electric field ablation control device. The pulsed electric field ablation control device comprises: an impedance detection part for performing fine impedance detection on a contacted tissue by using an electrode on an ablation catheter; the tissue thickness determining part is used for determining the thickness of the tissue according to the change of the detected impedance under different contact conditions; and the ablation control part is used for controlling the ablation catheter to carry out pulsed electric field ablation output according to the determined thickness of the tissue. According to the focusing electrode, the impedance of the contact tissue and the tiny impedance change under different contact conditions can be accurately detected, so that the tissue thickness can be calculated, proper ablation parameters can be matched, and complications caused by too large ablation parameters are avoided. In addition, according to the pulse electric field ablation control technology, the ablation depth can be determined, and excessive ablation is avoided.

The invention provides signal acquisition equipment for pulsed electric field ablation. The signal acquisition equipment comprises an input interface module, a signal conditioning circuit, a differential-to-single-ended circuit and a signal acquisition module, the input interface module comprises a first input interface and a second input interface; the signal conditioning circuit is arranged between the input interface module and the differential-to-single-ended circuit and comprises an adjustable resistance sub-circuit with an adjustable resistance value, a first end of the adjustable resistance sub-circuit is connected with the first input interface, a second end of the adjustable resistance sub-circuit is connected with the second input interface, and a sliding end of an adjustable resistor in the adjustable resistance sub-circuit is grounded; the first input end of the differential-to-single-end circuit is connected with the first end of the adjustable resistor sub-circuit, and the second input end of the differential-to-single-end circuit is connected with the second end of the adjustable resistor sub-circuit; and the signal acquisition module is connected with the output end of the differential-to-single-terminal circuit. According to the signal acquisition equipment provided by the embodiment of the invention, the accuracy of pulse signal acquisition can be improved.

The invention provides a heavy metal contaminated soil remediation method and device based on directional regulation and control of an electrode array, and the method comprises the following steps: filling heavy metal contaminated soil to be remediated into a soil chamber, and arranging the electrode array in the soil chamber; an electrolyte is added into the cathode chamber and the anode chamber respectively, so that the electrolyte enters the soil chamber, and the moisture content of the soil is maintained to be 20-50%; and under the condition that the pH value of the electrolyte in the cathode chamber and the pH value of the electrolyte in the anode chamber are maintained at 6.0-7.5, bipolar pulse electric fields are applied to the anode and the cathode, so that heavy metal ions in the heavy metal contaminated soil to be remediated are directionally migrated to the surface of the electrode array, and remediation is completed. Moreover, the remediation method and device are simple and convenient to operate, efficient, controllable and environment-friendly remediation of the heavy metal contaminated soil is achieved, good engineering applicability and economical efficiency are achieved, and the green development requirement of the soil remediation technology is met.

A pulsed field delivery device for delivery of electroporation treatment to cancerous and pre-cancerous regions of the gastrointestinal tract is described. It has a first expanding body coupled non-conductively to a second expanding body wherein the non-conductive coupling allows elements of the expanding bodies to sit on opposite sides of a tissue across which pulsed electric fields are applied. An elongate shaft has a proximal end which extends exterior of the patient so that a user can advance and withdraw the device when required. The device also comprises an elongate member or sheath which can be advanced over or retracted back off of the distal end of the device providing protection during device movement. The electrodes are arranged to radially expand and to move closer together to pinch diseased tissue being treated.

The invention provides a preparation method of a composite substrate for semiconductor device production, which comprises the following steps: putting raw material carbon into a reaction chamber in a hydrogen atmosphere, vacuumizing the reaction chamber, heating to 1000-1500 DEG C, such as 1000 DEG C, 1200 DEG C and 1500 DEG C, preserving heat for 1-3 hours, cooling and cleaning to obtain a carbon substrate; grinding and mixing a tantalum source, a tantalum fluoride and a fluxing agent to obtain coating powder; transferring the coating powder into a reaction chamber with a pulsed electric field, carrying out pulsed electric field assisted vapor deposition, and cooling to obtain a tantalum carbide pre-coating material with directionally arranged crystal orientations; and transferring the tantalum carbide pre-coating material into a high-temperature sintering furnace, and heating the tantalum carbide pre-coating material in an inert atmosphere at 1800-2400 DEG C for 0.5-6 hours to obtain the composite substrate which is used for producing a semiconductor device. Through directional arrangement of crystal orientations, the tantalum carbide coating achieves higher electrical conductivity and thermal conductivity.

The utility model is suitable for the technical field of pulsed electric field ablation catheters, and provides a pulsed electric field ablation catheter which comprises a catheter body part and an expansion part, the catheter body part comprises a main body tube and a push-pull tube, the push-pull tube is movably arranged in the main body tube in a penetrating mode, and at least part of the push-pull tube extends out of the far end of the main body tube; the expansion part comprises an expansion pipe, and a plurality of branch pipes are formed between the near end and the far end of the expansion pipe; the branch tube is provided with at least one treatment electrode, a cooling gap communicated with the external environment is arranged between the branch tube and the treatment electrode, the main tube is provided with a first perfusion channel, the branch tube is provided with a second perfusion channel, the first perfusion channel is communicated with the second perfusion channel, and the second perfusion channel is communicated with the cooling gap. According to the pulsed electric field ablation catheter provided by the invention, a perfusion hole does not need to be formed in the surface of the treatment electrode, the spark discharge phenomenon on the treatment electrode can be effectively avoided, and the reliability is relatively high.

The invention discloses a coal mine gas collaborative anti-reflection extraction method, which belongs to the field of coal mine gas extraction, and comprises the following steps: S1, drilling a plurality of vertical drilling wells and a plurality of horizontal drilling wells in a coal seam area to form a three-dimensional drilling network; s2, composite electric field fracturing is conducted, specifically, transient impact is conducted through a high-voltage pulse electric field, and then low-frequency electromagnetic waves are introduced for continuous action; s3, geothermal water in the underground abandoned mine is pumped through a high-pressure pump, the geothermal water is heated to the set temperature through a heat pump and then mixed with high-pressure nitrogen, the mixture is introduced into a wellhead of the three-dimensional well drilling network in a pulse mode, and water is pumped out after the set time and returned and conveyed into the underground abandoned mine; and S4, gas is extracted from the wellhead position through negative pressure adsorption equipment. By the adoption of the coal mine gas collaborative anti-reflection extraction method, advanced technologies such as a three-dimensional well drilling network, composite electric field fracturing and pulse type geothermal water and nitrogen mixed injection are combined, and the extraction rate is greatly increased.

The invention discloses a method for improving the quality of phyllanthus emblica fruit juice through an enzymolysis-assisted pulsed electric field, which comprises the following steps: firstly, carrying out preliminary enzymolysis treatment on phyllanthus emblica fruits through a low-concentration compound enzyme solution to form micropores in the surfaces of cell walls; then, the pore diameter of the preliminarily formed micropore area is further expanded under the action of a pulsed electric field, the cell structure is destroyed to form a pore channel, through combined regulation and control of enzymolysis and electric field parameters, efficient release of micromolecular nutritional ingredients such as vitamin C, polyphenol substances, total flavonoids and monosaccharide is achieved through the synergistic effect of the enzymolysis and the electric field parameters, and the effect of improving the nutrient content is achieved. Meanwhile, the excessive precipitation of macromolecular polysaccharide is limited, the taste of the fruit juice is improved, the clarity of the fruit juice and the stability of nutritional ingredients are ensured, the consistency of the taste of the product is maintained, in addition, the enzyme dosage is effectively reduced, the safety problem caused by enzyme residues is reduced, the enzymolysis time and the pulse intensity are also remarkably reduced, and the production cost is reduced; the method meets the requirement of green production and is suitable for industrial large-scale application.

The invention relates to the technical field of TGV packaging, in particular to an electroplating system for a TGV and panel-level packaging process. Comprising a tank body and environment maintenance module, a soluble anode and current redistribution module, a cathode clamp and substrate posture regulation and control module, a micro-area jet flow coupling array module, a pulsed electric field and impedance compensation module and an electroplating liquid peripheral circulation and online regeneration module, the thickness uniformity of a plating layer on a panel-level large-size substrate is remarkably improved through real-time closed-loop coupling of micro-area jet flow and current density and accurate correction of an adjustable shielding grid on edge current, the thickness uniformity of the plating layer on the panel-level large-size substrate is improved, and the thickness uniformity of the plating layer on the panel-level large-size substrate is improved. According to the method, the through hole filling void rate is reduced to an extremely low level, and bubble desorption, crystal nucleus homogenization and updating of an interface solution are effectively promoted by utilizing micro-vibration, dynamic variable immersion and periodic shaking functions of the cathode clamp, so that thickening of a diffusion layer is inhibited, and the defects of through hole filling void and the like are reduced.

The invention discloses a preparation method of mannan oligosaccharide, and relates to the technical field of organic agricultural fertilizers. According to the method, high-purity and high-efficiency mannan oligosaccharide is prepared by using an advanced process, and the method comprises the following specific steps: pretreatment of raw materials: mixing konjaku flour or guar gum with water to obtain a colloidal solution; adding beta-mannase and alpha-galactosidase into the colloidal solution, and carrying out enzymolysis under the assistance of a pulsed electric field; performing secondary separation on the enzymatic hydrolysate through an ultrafiltration membrane and a nanofiltration membrane, and collecting trapped fluid. A calcium ion solution is added into the trapped fluid for a complex reaction, then spray drying is conducted, and mannan oligosaccharide powder is obtained. According to the method, mannan oligosaccharide with concentrated purity and polymerization degree is prepared through ultrahigh pressure homogenization, pulsed electric field assisted enzymolysis and membrane separation technologies, the method has the advantages of high efficiency and environmental protection, and the preparation efficiency and the product quality are remarkably improved. The prepared mannan oligosaccharide can be applied to organic agricultural fertilizers, and can be compounded with humic acid and other substances to improve the biological activity and soil fertility of the fertilizers.