62 results about "Thermal ablation" patented technology

The invention belongs to the technical field of agricultural machinery and intelligent control, and particularly relates to an intelligent precise weeding robot based on multispectral recognition. The robot aims at solving the problems that in the prior art, due to visible light morphological recognition, the forms of crops and weeds are similar, and the recognition precision is low and the robustness is poor in the complex field environment. The robot comprises an autonomous mobile platform and a sensing operation assembly, the sensing operation assembly integrates a multi-mode sensing unit, a data fusion and decision core and a high-energy thermal ablation module, and the multi-mode sensing unit provides eight narrow-band pulse light with specific wavelengths through an active light source illumination module. Realizing synchronous acquisition of spectrum and space information by combining multispectral imaging and three-dimensional profile measurement; the data fusion and decision core performs registration, segmentation and classification on multi-source data to generate weed target coordinates; and the high-energy thermal ablation module implements 1470-nanometer laser accurate ablation based on the coordinates, and verifies the operation effect in real time through coaxial infrared thermal imaging. By means of the technical scheme, high-confidence-coefficient distinguishing and millimeter-level lossless precise weeding of crops and weeds in the complex farmland environment can be achieved.

The invention relates to the technical field of ablation path planning, in particular to a liver cancer thermal ablation path planning system based on deep reinforcement learning. The system comprises a target and dangerous area mask generation module, a pipeline distance field construction module, a thermal field prediction module, a breathing deformation prediction module, a multi-scale feature fusion module, a behavior preference reward module, a composite reward function module and a decision output module. Clinical pain points such as breathing interference, dangerous area avoidance and individualized adaptation are broken, the precision and safety of the liver cancer thermal ablation operation are improved, normal tissue damage and complications are reduced, intelligent decision support is provided for interventional therapy, and liver cancer minimally invasive therapy is promoted to be upgraded to precision and intelligence.

A thermal ablation-resistant, wear-resistant, and friction-reducing coated piston ring, a preparation method thereof and an engine are provided. An outer circumferential surface of a piston ring material matrix includes, from bottom to top, a wear-resistant and friction-reducing layer and a protective layer, and the protective layer is a single nitride layer or a multi-element nitride layer. The piston ring is arranged with the wear-resistant and friction-reducing layer and the protective layer from bottom to top. When the piston ring is installed in the engine, the high-temperature and high-pressure gas flow impacts the piston ring and contacts the protective layer on the surface of the piston ring, while the inner diamond-like carbon coating (DLC) functional layer is completely “encapsulated” and protected by the outer protective layer. The protective layer possesses higher ablation resistance compared to the DLC layer, effectively preventing phase transformation in the internal DLC layer.

The invention relates to the field of spectrum external field testing, and discloses a rocket engine fuel gas measuring device which comprises a support and a hollow probe assembly installed on the support. In order to solve the problems of high-temperature and high-pressure impact and thermal ablation of the tail flame of the rocket, the support and the probe assembly are both designed to be of a wedge-shaped structure, internal circulating water paths are arranged on the support and the probe assembly for forced cooling, the probe assembly is of a U-shaped structure, and an optical measurement light path is arranged in the probe assembly. According to the optical measurement light path, gas parameters are measured through a light refraction principle by using a lighting tube, a prism and a collimating lens connector which are inserted into a probe, so that a measurement component is far away from a high-temperature area. According to the invention, the wedge-shaped structure, active water cooling and high-temperature-resistant materials are combined, so that the effects of good cooling performance, stable structure and ablation resistance are realized, and the measurement precision in a harsh environment can be ensured.

The present invention relates to a method (100) for dielectric spectroscopy of a material or a tissue under test, comprising the following steps: measuring (110) the reflection coefficient (11) signal as a function of the frequency of said material or tissue under test, by a vector network analyzer (3), wherein a single applicator (5) is in contact with said material or a tissue under test and wherein the applicator (5) is operatively connected to the vector network analyzer (3); multiplying (120) the reflection coefficient (11) signal with the frequency behavior of an ultra-wide band (UWB) signal as a synthetic applicator excitation; converting (130) the signal of the previous step into the time domain by an Inverse Fourier Transform (IFT); suppressing (140) part of the converted signal of the converting step (130), according to the applicator (5) geometry; converting back (150) the signal of the suppressing step (140) to the frequency domain; and extracting (160) from the frequency signal converted the dielectric properties (162) and / or estimating (170) the dimension of the material or a tissue under test and / or of an ablated area of the material or a tissue under test thereof. The present invention also relates to an apparatus for dielectric spectroscopy (1).

Disclosed are a compatible system and a compatible method for synchronize working of magnetic resonance imaging and focused ultrasound thermal ablation. The compatible system for synchronize working includes a magnetic resonance device and a focused ultrasound device, further includes a signal collector and a control circuit connected to the signal collector. In an imaging process of the magnetic resonance device, the signal collector is configured to detect a radio frequency (RF) signal of the magnetic resonance device, and the control circuit is configured for recording a trigger time of the RF signal, generating an enable signal triggering the focused ultrasound device to start heating based on the trigger time of the RF signal, and controlling a heating duration of the focused ultrasound device according to an echo time.

The application relates to a preparation method of a poly-pyrrole-prussian blue hybrid photothermal nanolaser, polyvinylpyrrolidone is added into deionized water and stirred until completely dissolved, pyrrole and potassium ferrocyanide are added into the obtained polyvinylpyrrolidone solution, stirring is uniformly conducted, then ferric chloride hexahydrate is added, sufficient stirring and reaction are conducted, a reaction liquid is obtained, after the precipitation is removed through centrifugation, the supernatant is dialyzed and vacuum freeze-dried, and the poly-pyrrole-prussian blue hybrid photothermal nanolaser is obtained.Compared with the prior art, the method has lower requirements on equipment, mild reaction conditions, is green and environment-friendly, is suitable for large-scale production, the prepared photothermal nanolaser has good photothermal ablation effect under the irradiation of near-infrared light, can significantly inhibit the growth of tumor cells, the photothermal nanolaser also has good oxygen production performance, can decompose hydrogen peroxide to generate oxygen, and can further improve the tumor hypoxic microenvironment and enhance the in-situ thermal ablation treatment effect of the tumor, thereby providing a potential technical means for relieving the tumor hypoxic microenvironment and strengthening the in-situ thermal ablation.

The invention relates to the technical field of thermal ablation, in particular to a thyroid nodule ultramicro-invasive ablation precise puncture positioning method, which comprises the following steps of: acquiring continuous gray frames and extracting tissue gray to complete normalization and phase demodulation to generate phase time data; detecting a brightness peak value according to phase time data to obtain a tip echo, calculating a phase gradient in a neighborhood by using a fixed window to generate a stable domain data set, calculating a spatial range according to a stable domain, extracting a phase change signal along with time, and completing frequency domain dominant frequency extraction and period analysis to generate a period consistent region; according to the method, the continuous image phases are extracted, the time sequence is combined, the needle point recognition stability is enhanced, the echo region is restrained through the brightness peak value and the phase gradient, and the accuracy of positioning is improved. Position judgment is enhanced through spatial range and period analysis, and the guiding precision is improved by combining a three-dimensional distance and a symbol sequence.

This invention relates to a composite high and low temperature thermal ablation system, and pertains to the field of ablation technology. The composite high and low temperature thermal ablation system of this invention adjusts the pressure of the working fluid storage tank by controlling the number and diameter of the ablation needles connected in the pipeline, and adjusts the opening of the phase separation valve to maintain the phase separation valve at the target temperature. This allows for rapid cooling with minimal consumption of working fluid, regardless of the combination of ablation needles.

The utility model discloses a heating instrument for executing thermal ablation in intestinal tracts, and relates to the technical field of medical instruments, the heating instrument comprises a sheath tube, a bag body and a liquid injection tube, an inner tube is arranged in the sheath tube, and a heating electrode and a temperature measuring electrode are arranged in the inner tube; the bag body is arranged on the outer wall of the far end of the sheath tube, a heating wire is arranged in the bag body, spiral electrode connectors are integrally formed at the two ends of the heating wire, and the electrode connectors are wrapped in the sheath tube and fixed to the heating electrode in a multi-point welding mode; the liquid injection tube is arranged at the near end of the sheath tube, a liquid injection channel is formed between the inner tube and the sheath tube, one end of the liquid injection channel is communicated with the liquid injection tube, and the other end of the liquid injection channel is communicated with the bag body. The spiral electrode connectors are arranged at the two ends of the heating wire, multi-point welding is formed, welding is facilitated, and the firmness of connection between the heating wire and the heating electrode can be effectively improved through a plurality of welding positions.

The application provides an integrated flame stabilizer with a boss in a trailing edge cavity, which comprises a flame stabilizer, an oil injection rod, a cooling gas inlet pipe, a trailing edge wing plate and a trailing edge boss. In one aspect, the trailing edge cavity is formed downstream of the rear side plate of the flame stabilizer by the trailing edge wing plate, and the trailing edge boss is arranged on the rear side plate, so that the cooling vortex is formed in the trailing edge cavity by the trailing edge boss, the rear side plate and the cooling gas holes arranged on the trailing edge wing plate, the flame stabilizer is isolated from the backflow area downstream of the flame stabilizer, the heat load of the flame stabilizer is reduced, and the thermal ablation problem is avoided; meanwhile, the cooling method has little influence on the backflow area behind the stabilizer, and the flame stabilizing function of the flame stabilizer is not damaged. In another aspect, the cooling gas can also cool the oil injection rod after entering the inside of the flame stabilizer, so that the coking problem of the oil injection rod is solved.

This invention discloses a microwave ablation electrode, relating to the field of medical device technology. It mainly includes a main needle body, whose working end can release microwave energy to achieve microwave ablation. The main needle body is equipped with a non-working end circulating cooling structure and a working end liquid injection structure. The non-working end circulating cooling structure allows a cooling medium to reach the non-working end of the main needle body to cool the non-working end and surrounding tissue, and also allows for the return flow of the cooling medium. The working end liquid injection structure allows a cooling medium to reach the working end of the main needle body to cool the working end and surrounding tissue, and also allows the cooling medium to be injected into the lesion tissue, absorbing microwave energy to form steam, achieving steam thermal ablation. This invention achieves dual ablation through steam thermal ablation and microwave ablation, improving the ablation effect, reducing the temperature of the working end of the microwave ablation electrode, and increasing the moisture content of the tissue surrounding the working end, thus reducing carbonization of the lesion tissue.

The invention discloses a cryogenic radiofrequency ablation needle and system, and belongs to the technical field of cryoablation, the cryogenic radiofrequency ablation needle comprises a needle head part, an adjusting handle part, a delivery pipe part, a quick connector part, a rewarming temperature measurement ablation plug part and a radiofrequency ablation plug part, the needle head part is connected to the adjusting handle part, and the delivery pipe part is connected to the radiofrequency ablation plug part; the adjusting handle part is used for connecting the needle head part and the conveying pipe part, the quick connector part is connected to the conveying pipe part, and the rewarming temperature measurement ablation plug part is connected with the radio frequency ablation plug part. On the basis of a cryoablation probe of a high-pressure nitrogen throttling freezing technology, the rewarming module and the radio frequency ablation module are added, central control switching of the three modules is achieved, the integrated structure design of the freezing module, the rewarming module and the radio frequency module is achieved, the integrated structure can be used in a multi-module combined mode and can also be used independently, and the cost is reduced. The cold ablation function and the thermal ablation function are mutually complemented.

The invention discloses vein closed cryoablation equipment which comprises a low-temperature coolant circulating system, an adjustable cryoablation catheter and a temperature real-time monitoring feedback system, and is an innovative cryoclosure system provided for treatment of great saphenous varicosity. Based on latest clinical research data and an engineering principle, compared with the existing conventional thermal ablation technology, the vein closing cryoablation equipment has the advantages that a better closing effect can be realized, nerve injury is greatly reduced, and intraoperative pain is relieved.

To provide medical probes. [Solution] A medical probe may include electrodes for ablation, for sensing proximity to tissue, and / or for monitoring electrical signals within the cardiovascular system to identify aberrant-conducting tissue sites causing arrhythmias. The electrodes may be oriented on an end-effector assembly, such as a basket assembly, so that one side of the electrode is positioned to contact the tissue and the opposite side is prevented from contacting the tissue. To enable both efficient energy delivery and high sensitivity for ECG sensing, an impedance-reducing coating may be positioned on the tissue-contact side, and an impedance-increasing coating may be applied to the opposite side. The impedance-increasing coating on an IRE electrode may be thin enough to allow energy to be delivered through the coating during ablation. An RF electrode may have a mass sufficient to carry electrical energy for thermal ablation.

The invention discloses an ablation area image segmentation method and system in lung cancer thermal ablation, a medium and equipment. The segmentation method comprises the following steps: constructing a lightweight converter based on in-window self-attention and inter-window self-attention cascading; inputting the image into a lightweight converter, and encoding to obtain a multi-scale feature; performing linear mapping on the multi-scale features to obtain mapping features with the same embedding dimension, enabling the spatial dimensions of the mapping features to be the same by using an up-sampling operation, fusing the mapping features by using a channel superposition operation, and generating a coarse segmentation result by using a convolution module; and after superposing the coarse segmentation result and the image channel, inputting the result into an encoder structure of a convolutional network to obtain a convolutional coding feature, fusing the convolutional coding feature with a multi-scale feature, and performing channel superposition with a decoder feature to generate a fine segmentation result. According to the method, complex image features can be extracted, the robustness is high, and the problem that the global modeling capability of the convolutional network is weak is solved.

Aspects and embodiments relate to a tissue mimicking material, a clinical phantom including a tissue mimicking material and a method of manufacture of a tissue mimicking material. According to one aspect there is provided: a tissue mimicking material comprising: an alginate matrix; and an ablation-sensitive agent distributed through the alginate matrix. Aspects and embodiments recognise that use of an alginate matrix as a base for a tissue mimicking material provides relatively low cost material having various physical properties and characteristics which can be tuned or refined to simulate the characteristics of a mammalian tissue which the alginate matrix is intended to mimic. In relation to use of an alginate material in the context of thermal and / or pulsed electric field ablation simulation, it has been recognised that an alginate material may be appropriately temperature stable and not degrade upon exposure to high, or low, ablation temperatures, or upon exposure to ablation levels of pulsed electric field. Distribution of an appropriately selected ablation-sensitive agent through the alginate material may allow a change caused by application of an ablation technique to the tissue mimicking material to be observed.

The invention relates to the technical field of thermal therapy, in particular to an MRI imaging-based ultrasonic-assisted thermal therapy system, which is characterized in that the MRI imaging-based ultrasonic-assisted thermal therapy system comprises an MRI imaging module, a heat source module, an ultrasonic monitoring module and a control module, and the control module comprises a data fusion processing unit, a closed-loop power control unit and a mechanical arm trajectory planning unit; by means of multi-source fusion of MRI temperature mapping, ultrasonic real-time imaging and optical fiber temperature sensing, low-delay and high-precision tissue temperature and state monitoring is achieved, prediction-correction closed-loop control based on the Pennes equation is combined, the temperature control precision and the response speed are improved, a multi-focus and track type combined heating strategy is supported, the treatment time is greatly shortened, and the treatment effect is improved. According to the invention, the MRI compatible mechanical arm and the wearable fixing device are matched, high repeated positioning and flexible probe pose optimization are realized, the stability and safety of the treatment process are ensured through a multi-stage safety interlocking and redundancy monitoring mechanism, and efficiency, accuracy and clinical applicability are considered in thermal ablation treatment.

A combination ablation probe includes a shell configured to be positioned at a target tissue in a patient and a conduit positioned inside the shell. The conduit is configured to supply a cryo-fluid toward a tip of the probe. The probe also includes a heater positioned radially outward of the conduit in the shell and at least one heat transfer element in thermal communication with the heater and the shell.

Disclosed are methods and systems, comprising real-time dense algorithms calculating the speed-of-sound shift between acoustic acquisitions, that allows enhanced noninvasive temperature evaluation during treatment such as thermal ablation.

A medical probe can include electrodes for ablation and sensing proximity to tissue and / or monitoring electrical signals within the cardiovascular system to identify aberrant conductive tissue sites that are responsible for an arrhythmia. The electrodes can be oriented on an end effector assembly, such as a basket assembly, such that one side of an electrode is positioned to contact tissue and the opposite side is inhibited from contacting tissue. To enable both efficient delivery of energy as well as high sensitivity for ECG sensing an impedance reducing coating can be positioned on the tissue contacting side and an impedance increasing coating can be applied on the opposite side. The impedance increasing coating of an IRE electrode can be thin enough to allow energy to be delivered through the coating during ablation. An RF electrode an have sufficient mass to carry electrical energy for thermal ablation.

This invention belongs to the field of medical device technology, and specifically relates to a pulsed field ablation catheter system for coronary artery myocardial bridging. It includes a pulsed electric field ablation structure and a disposable pulsed electric field ablation catheter. A connecting wire is located on the back side of the pulsed electric field ablation structure, and the other end of the connecting wire is movably engaged with the disposable pulsed electric field ablation catheter. By using the disposable pulsed electric field ablation catheter, the catheter body drives an inflatable balloon through the arterial tube to reach the myocardial bridging lesion. The contrast fluid injected into the external tube gradually expands the balloon, causing it to unfold and allowing the electrode pads to adhere to the vessel wall for pulsed electric field ablation. This eliminates the need for the strong adhesion required by traditional thermal or cold ablation, effectively avoiding vascular damage caused by excessive local energy, and providing an efficient and reliable solution for the clinical treatment of coronary artery myocardial bridging.

The present application relates to the technical field of medical devices, in particular to a steam ablation system and a control method thereof. The steam ablation system comprises a steam device, a sterile water delivery device, a pressure relief device and an ablation needle. The sterile water delivery device is used to introduce sterile water into the steam device at a constant flow rate. The ablation needle can be pushed out or withdrawn relative to the steam device. When the ablation needle is pushed out relative to the steam device, the steam discharged by the steam device is discharged through the ablation needle to achieve thermal ablation on the tissue. When the ablation needle is withdrawn relative to the steam device, the steam discharged by the steam device can be discharged through the pressure relief device. During the treatment interval, excessive steam is prevented from being discharged through the ablation needle to scald the patient. Since the sterile water delivery device always introduces sterile water into the steam device at a constant flow rate, the treatment efficiency is improved, and the occurrence of negative pressure at the ablation needle site is also avoided. The steam ablation system control method improves the treatment efficiency and avoids the occurrence of negative pressure at the ablation needle site.

The application relates to the technical field of tumor hyperthermia, in particular to a temperature field acquisition method and device for tumor thermal ablation surgery, wherein the method comprises the following steps: segmenting a three-dimensional tumor model from a three-dimensional magnetic resonance image in a target liver; calculating the centroid position of the three-dimensional tumor according to the three-dimensional tumor, and solving the ellipsoid parameters of the three-dimensional tumor; querying a preset database by using the ellipsoid parameters to obtain the closest ellipsoid data, and acquiring the current temperature field distribution from the closest ellipsoid data. Therefore, the problems in the prior art that the finite element calculation is huge in amount, time-consuming, and the temperature field cannot be acquired and monitored in real time, the accuracy and real-time performance of the surgery are reduced, and the requirements of the tumor thermal ablation surgery cannot be met are solved.

The invention provides a marker detection kit for typing or prognosis evaluation after liver cancer thermal ablation, a detection analysis system and application of the marker detection kit and the detection analysis system. In order to solve the clinical problems that after thermal ablation treatment, hepatocellular carcinoma is prone to relapse and the mechanism is unknown, in a clinical sample and an orthotopic xenograft model derived from a patient, it is jointly confirmed that a remarkable DNA hypermethylation phenomenon exists in residual and relapsed HCC tissue after ablation, and the phenomenon is accompanied by remarkable up-regulation of DNMT1; therefore, heat stress can trigger and promote an epigenetic-metabolic cascade reaction of tumors by activating a DNA hypermethylation 5mC mechanism. On the basis, it is clear that DNMT1-mediated DNA hypermethylated 5mC is one of important mechanisms of HCC recurrence after thermal ablation, an accurate detection marker is provided for recognizing the recurrence risk, and a detection and analysis system is established to improve the layered diagnosis capacity after liver cancer thermal ablation, so that the prognosis and survival conditions of patients are improved.

The invention relates to a heatproof alloy based on oxidation film phase design and a preparation method and application thereof, and relates to the technical field of heatproof alloys resistant to pneumatic thermal ablation.The preparation method comprises the steps that (1) mixed components including tantalum particles, titanium particles and silicon particles are dried and evenly mixed, and a mixture is obtained; (2) the mixture is placed in a reactor for vacuum arc melting, and an alloy is obtained; and (3) carrying out post-treatment on the alloy to obtain the heat-proof alloy. The prepared heat-proof alloy can form a liquid-phase anti-oxidation film with the self-healing characteristic under the high-temperature aerodynamic heat condition, continuous protection of dynamic fluidity can be provided, and the stability and reliability of the alloy in the high-temperature aerodynamic environment generated in the high-Mach-number flight process of an aircraft are improved.

The invention discloses an intelligent prediction system and method for early recurrence risk after liver cancer thermal ablation, and aims to solve the technical problem that prediction is not timely and inaccurate due to the fact that an existing prediction model ignores intraoperative dynamic information. According to the method, dynamic time sequence data such as tissue impedance and power in the thermal ablation process are collected in real time, and preoperative static data such as tumor size and alpha fetoprotein level are combined, so that a double-branch fusion prediction model is constructed. The model comprises a time sequence processing branch used for learning dynamic data time dependence and a static processing branch used for extracting static data features. By fusing the features of the two branches, the model can output a probability value representing the postoperative early recurrence risk. According to the method and the system, instant accurate risk stratification after operation is realized, and further, intraoperative intervention can be guided through real-time feedback, so that the early recurrence risk is actively reduced, and the prognosis of a patient is improved.

The invention relates to the technical field of medical equipment, and provides a multi-mode focused ultrasound system based on supply blood vessel occlusion, comprising: a focused ultrasound unit comprising an ultrasonic treatment head and an ultrasonic driving circuit connected with each other; the detection imaging unit is used for detecting the target tissue to obtain target tissue data containing blood vessel information; the control unit is used for determining an irradiation plan based on the target tissue data, and executing the irradiation plan through the focused ultrasound unit, including: performing focused ultrasound irradiation on a supply blood vessel of a target tissue in a heat effect mode to form thermal ablation; and irradiating the target tissue that blocks blood supply in the histotripsy mode in the event that the histotripsy mode is adapted to the target tissue. The system disclosed by the invention can be used for realizing multi-mode cooperative implementation of supply blood vessel treatment, heat effect and tissue destruction of target tissues, and effectively solves the problems of tissue blood vessel residue, single treatment mode and the like in focused ultrasonic treatment in related technologies.

The application discloses a kind of aerodynamic thermal ablation matching coupling simulation design method, S1, for the aircraft shape of un-ablation, select flight orbit typical state point to calculate incoming flow condition, simulate the thermal environment of different types of thermal protection material lap joint part;S2, carry out ablation simulation analysis to determine the ablation amount and ablation profile of the two sides of lap joint part, calculate the initial ablation matching step height h0 of two sides material;S3, estimate the ablation deterioration factor, estimate the ablation matching step height H after ablation deterioration effect based on h0;Ablation step shape modeling is carried out here, obtain the aircraft shape with local ablation step shape;S4, regenerate aircraft surface and outflow field grid, carry out three-dimensional aerodynamic thermal simulation design, give the thermal environment of material lap joint part;S5, carry out ablation simulation analysis again, calculate the secondary ablation matching step height h1;S6, compare h1 with H, confirm the simulation end after estimating the ablation amount in S3 envelope flight test ablation amount.