105 results about "Thermal ablation" patented technology

The invention relates to the technical field of medical equipment, and provides a focused ultrasound system with multiple treatment modes. The drive circuit comprises a signal generation module which outputs a first ultrasonic generation signal suitable for a thermal ablation mode or a second ultrasonic generation signal suitable for a histotripsy mode; the energy amplification module comprises a signal end, a power supply end and an output end coupled with the ultrasonic transducer; the energy amplification module comprises an isolation driving circuit which outputs a first switch driving signal and a second switch driving signal which are opposite based on an input ultrasonic generation signal; and the power amplification circuit comprises a second switch unit and a first switch unit which are set to be in opposite switch states by opposite driving signals so as to output ultrasonic driving signals to excite the ultrasonic transducer to form focused ultrasound in a histotripsy mode or a thermal ablation mode. The driving circuit is simple in structure and easy to realize, and can meet power supply requirements of various modes such as thermal ablation, histotripsy and the like.

The invention belongs to the technical field of physical thermal ablation, and relates to a physical thermal ablation energy regulation and control method based on intelligent feedback, and the method comprises the steps: collecting point-shaped temperature data, impedance data and ultrasonic data, eliminating the asynchronization and heterogeneity problems through space-time alignment, and combining with focus region segmentation, thereby achieving the energy regulation and control of the physical thermal ablation. Discrete data and continuous images are integrated into a voxelization data cube containing space coordinates, physical attributes and semantic tags, then the temperature change rate and the impedance change rate are calculated based on the voxelization data cube, and then a morphological prediction network is fused with multi-modal features to output a voxel-level ablation probability graph. The method comprises the following steps: realizing prospective prediction of an ablation range, ensuring ablation accuracy by morphological deviation through a three-layer parallel regulation and control strategy, preventing and controlling local overheating by temperature gradient, avoiding tissue carbonization by an impedance change rate, and cooperatively deciding through multi-dimensional indexes to solve the contradiction that single regulation and control cannot give consideration to accurate coverage of a focus and protection of normal tissues; and misjudgment caused by abnormity of single data is avoided.

A high and low temperature composite ablation surgery system, relating to the technical field of cryotherapy, used to improve the safety and effectiveness of therapy, and comprising a main unit (100) and a cryogenic-thermal ablation probe (200) connected to the main unit (100). The main unit (100) comprises a cold working medium supply system (300), a hot working medium supply system (400), and a working medium distribution system (500). The working medium distribution system (500) can respectively control the cold working medium supply system (300) to deliver a cold working medium to the cryogenic-thermal ablation probe (200) and control the hot working medium supply system (400) to deliver a hot working medium to the cryogenic-thermal ablation probe (200). Therefore, after low-temperature therapy is completed, a therapy area can be quickly rewarmed, thereby providing a basis for improving the safety, economy and convenience of the surgery.

The invention belongs to the technical field of agricultural machinery and intelligent control, and particularly relates to an intelligent precise weeding robot based on multispectral recognition. The robot aims at solving the problems that in the prior art, due to visible light morphological recognition, the forms of crops and weeds are similar, and the recognition precision is low and the robustness is poor in the complex field environment. The robot comprises an autonomous mobile platform and a sensing operation assembly, the sensing operation assembly integrates a multi-mode sensing unit, a data fusion and decision core and a high-energy thermal ablation module, and the multi-mode sensing unit provides eight narrow-band pulse light with specific wavelengths through an active light source illumination module. Realizing synchronous acquisition of spectrum and space information by combining multispectral imaging and three-dimensional profile measurement; the data fusion and decision core performs registration, segmentation and classification on multi-source data to generate weed target coordinates; and the high-energy thermal ablation module implements 1470-nanometer laser accurate ablation based on the coordinates, and verifies the operation effect in real time through coaxial infrared thermal imaging. By means of the technical scheme, high-confidence-coefficient distinguishing and millimeter-level lossless precise weeding of crops and weeds in the complex farmland environment can be achieved.

The invention provides a training method for a thermal ablation related image generation model, and the method comprises the steps: collecting a rapid magnetic resonance sequence image and a thermal ablation related image in the same thermal ablation process through a reproducible thermal ablation simulation test; forming a training sample by taking the fast magnetic resonance sequence image as a sample and taking a corresponding thermal ablation related image as annotation data; and generating a training sample set by referring to the previous steps, and training a deep learning model to obtain a thermal ablation related image generation model. According to the method, the rapid magnetic resonance sequence image and the corresponding thermal ablation related image data are acquired through the reproducible thermal ablation simulation test, and the defects that real thermal ablation data are insufficient and training data of the model are difficult to acquire are effectively overcome. Moreover, the user can acquire the image through the rapid magnetic resonance sequence in the clinical thermal ablation process and generate the thermal ablation related image by using the trained thermal ablation related image generation model, and the real-time performance and accuracy of ablation monitoring are both considered.

The invention relates to the technical field of ablation path planning, in particular to a liver cancer thermal ablation path planning system based on deep reinforcement learning. The system comprises a target and dangerous area mask generation module, a pipeline distance field construction module, a thermal field prediction module, a breathing deformation prediction module, a multi-scale feature fusion module, a behavior preference reward module, a composite reward function module and a decision output module. Clinical pain points such as breathing interference, dangerous area avoidance and individualized adaptation are broken, the precision and safety of the liver cancer thermal ablation operation are improved, normal tissue damage and complications are reduced, intelligent decision support is provided for interventional therapy, and liver cancer minimally invasive therapy is promoted to be upgraded to precision and intelligence.

The invention discloses a curative effect evaluation system for treating liver cancer by combining HDRBT with thermal ablation in multi-modal radiomics, and relates to the field of liver cancer treatment, and the system comprises a multi-modal image data acquisition module which is used for collecting multi-modal image data; the three-dimensional visual model construction module is used for reconstructing a three-dimensional structure of liver tumors, peripheral blood vessels and bile ducts through an image segmentation algorithm, and generating a visual model by fusing radiomics characteristics; the combined treatment plan generation module is used for integrating the dosimetry parameters of the HDRBT and the process parameters of the thermal ablation, optimizing a catheter implanting path, the position of a thermal ablation electrode and a treatment sequence, and generating a combined treatment scheme; and the curative effect evaluation module is used for quantitatively analyzing tumor volume change, ablation boundary integrity and residual tumor activity through accurate registration of multi-modal images before and after treatment. According to the scheme, the problems of incomplete thermal ablation and high recurrence rate of hepatocellular carcinoma can be solved, and full-chain technical support is provided for clinical precise application.

An apparatus for thermal ablation testing is provided. The apparatus comprises: a chamber; an optically transparent window in the chamber; a sample holder inside the chamber; a test sample in the sample holder; a number of bare-wire thermocouples connected to the test sample, wherein the thermocouples generate temperature data in the form of voltage; a mass balance inside the chamber, wherein the mass balance is configured to hold the sample holder and dynamically detect changes in mass of the test sample; an external radiant heat source configured to heat the test sample through the window; and a pyrometer directed at the test sample.

A thermal ablation-resistant, wear-resistant, and friction-reducing coated piston ring, a preparation method thereof and an engine are provided. An outer circumferential surface of a piston ring material matrix includes, from bottom to top, a wear-resistant and friction-reducing layer and a protective layer, and the protective layer is a single nitride layer or a multi-element nitride layer. The piston ring is arranged with the wear-resistant and friction-reducing layer and the protective layer from bottom to top. When the piston ring is installed in the engine, the high-temperature and high-pressure gas flow impacts the piston ring and contacts the protective layer on the surface of the piston ring, while the inner diamond-like carbon coating (DLC) functional layer is completely “encapsulated” and protected by the outer protective layer. The protective layer possesses higher ablation resistance compared to the DLC layer, effectively preventing phase transformation in the internal DLC layer.

The invention relates to the field of spectrum external field testing, and discloses a rocket engine fuel gas measuring device which comprises a support and a hollow probe assembly installed on the support. In order to solve the problems of high-temperature and high-pressure impact and thermal ablation of the tail flame of the rocket, the support and the probe assembly are both designed to be of a wedge-shaped structure, internal circulating water paths are arranged on the support and the probe assembly for forced cooling, the probe assembly is of a U-shaped structure, and an optical measurement light path is arranged in the probe assembly. According to the optical measurement light path, gas parameters are measured through a light refraction principle by using a lighting tube, a prism and a collimating lens connector which are inserted into a probe, so that a measurement component is far away from a high-temperature area. According to the invention, the wedge-shaped structure, active water cooling and high-temperature-resistant materials are combined, so that the effects of good cooling performance, stable structure and ablation resistance are realized, and the measurement precision in a harsh environment can be ensured.

The present invention relates to a method (100) for dielectric spectroscopy of a material or a tissue under test, comprising the following steps: measuring (110) the reflection coefficient (11) signal as a function of the frequency of said material or tissue under test, by a vector network analyzer (3), wherein a single applicator (5) is in contact with said material or a tissue under test and wherein the applicator (5) is operatively connected to the vector network analyzer (3); multiplying (120) the reflection coefficient (11) signal with the frequency behavior of an ultra-wide band (UWB) signal as a synthetic applicator excitation; converting (130) the signal of the previous step into the time domain by an Inverse Fourier Transform (IFT); suppressing (140) part of the converted signal of the converting step (130), according to the applicator (5) geometry; converting back (150) the signal of the suppressing step (140) to the frequency domain; and extracting (160) from the frequency signal converted the dielectric properties (162) and / or estimating (170) the dimension of the material or a tissue under test and / or of an ablated area of the material or a tissue under test thereof. The present invention also relates to an apparatus for dielectric spectroscopy (1).

A method and a system for thermally or hyperthermally treating an object. A precipitating hydrophobic injectable liquid (PHIL) embolic agent is prepared and enhanced with a magnetic nanoparticle (NP). A delivery device is advanced to a target area and the PHIL−IONP embolic agent is injected directly at the target area. The PHIL and IONPS are observed in-situ using complementary imaging and an impulse is applied to the target area to generate heat sufficient to thermally ablate or induce hyperthymia at the target area. Additional impulses applied to the target areas at later times generate heat sufficient to ablate or induce hyperthymia at the target.

The invention provides a magnetic resonance image reconstruction method and a model training method. The model training method comprises the following steps: acquiring a thermal ablation magnetic resonance image data set; for the continuous time magnetic resonance image at each fault, generating a training sample in a time down-sampling mode, and adding the training sample into a training sample set; and training a deep learning model by using the training sample set to obtain a magnetic resonance image reconstruction model. According to the method, the continuous time magnetic resonance images at the plurality of faults in the thermal ablation process are obtained, the training samples are generated for the magnetic resonance image at each fault in a time down-sampling mode and used for training the deep learning model, the model can supplement the down-sampling time sequence, the acquisition amount of magnetic resonance data in the thermal ablation process is reduced, and the thermal ablation efficiency is improved. And the real-time performance of data acquisition is improved. Moreover, the data set covers the whole process and all-position data of thermal ablation, so that the trained model better meets the requirements of a thermal ablation scene, and the accuracy of the reconstructed data is higher.

The application is a urethral catheter with conductive structure, which comprises a flexible catheter, the flexible catheter enters the human bladder through the urethra, the outer surface of the flexible catheter is partially provided with a conductive structure, the conductive structure is arranged at the prostate part of the outer distal end of the flexible catheter to assist freezing and electric ablation, the flexible catheter is internally provided with a liquid guide channel and a liquid guide opening is arranged at the distal end of the flexible catheter, the urethral catheter has a temperature protection effect, a temperature protection channel is divided into a liquid inlet channel and a liquid outlet channel by an inner sleeve and an outer sleeve, a surface electrode on the outer wall of the inner sleeve is connected to the circuit of a host, and the conductive structure only conducts electricity and does not have an electrochemical reaction. The application is used for cooperating to complete electric effect or electric ablation diagnosis and treatment effect and freezing, radio frequency and microwave and other thermal ablation, can avoid cold and hot damage or electric damage to the urethra or the prostate, has a temperature adjusting function and a simple structure and is easy to adjust and control.

Disclosed are a compatible system and a compatible method for synchronize working of magnetic resonance imaging and focused ultrasound thermal ablation. The compatible system for synchronize working includes a magnetic resonance device and a focused ultrasound device, further includes a signal collector and a control circuit connected to the signal collector. In an imaging process of the magnetic resonance device, the signal collector is configured to detect a radio frequency (RF) signal of the magnetic resonance device, and the control circuit is configured for recording a trigger time of the RF signal, generating an enable signal triggering the focused ultrasound device to start heating based on the trigger time of the RF signal, and controlling a heating duration of the focused ultrasound device according to an echo time.

The utility model discloses a testing device for simulating the high-temperature thermal ablation behavior of a material, which comprises a machine body, a bearing unit, a heat source unit and a gas circuit unit, the machine body is provided with a test cavity, and the machine body is provided with a window which is communicated with the test cavity and can be closed; the bearing unit is arranged in the test cavity, and a test sample is placed on the bearing unit; and the heat source unit is used for jetting flames to the test sample. The device has the beneficial effects that in the ablation test process, waste gas in the test cavity can be extracted, treated and discharged through the waste gas recovery assembly, so that the problem that the waste gas is directly discharged into the air to pollute the surrounding environment is avoided, and after the ablation test is finished, cooling gas can be pumped into the test cavity through the cooling assembly, so that the cooling efficiency is improved. The test sample and the whole test device are cooled uniformly and efficiently, so that the thermal load of the high-temperature test on the equipment is reduced, and the service life of the device is prolonged.

A method for treatment of volume of interest (VOI), for example tumor, comprising a device for application of therapy in multi sites in a pre-defined volumetric array through a single needle insertion into the body. Therapies applied by this method include injection of therapeutic agents, including cytotoxic, immunologic and biologic drugs or drug combinations; radioactive substances; thermal ablation including radiofrequency ablation, microwave ablation, or cryoablation. The method addresses the problem of inadequate distribution of therapy throughout the VOI through a single needle insertion.

The application relates to a preparation method of a poly-pyrrole-prussian blue hybrid photothermal nanolaser, polyvinylpyrrolidone is added into deionized water and stirred until completely dissolved, pyrrole and potassium ferrocyanide are added into the obtained polyvinylpyrrolidone solution, stirring is uniformly conducted, then ferric chloride hexahydrate is added, sufficient stirring and reaction are conducted, a reaction liquid is obtained, after the precipitation is removed through centrifugation, the supernatant is dialyzed and vacuum freeze-dried, and the poly-pyrrole-prussian blue hybrid photothermal nanolaser is obtained.Compared with the prior art, the method has lower requirements on equipment, mild reaction conditions, is green and environment-friendly, is suitable for large-scale production, the prepared photothermal nanolaser has good photothermal ablation effect under the irradiation of near-infrared light, can significantly inhibit the growth of tumor cells, the photothermal nanolaser also has good oxygen production performance, can decompose hydrogen peroxide to generate oxygen, and can further improve the tumor hypoxic microenvironment and enhance the in-situ thermal ablation treatment effect of the tumor, thereby providing a potential technical means for relieving the tumor hypoxic microenvironment and strengthening the in-situ thermal ablation.

The invention relates to the technical field of thermal ablation, in particular to a thyroid nodule ultramicro-invasive ablation precise puncture positioning method, which comprises the following steps of: acquiring continuous gray frames and extracting tissue gray to complete normalization and phase demodulation to generate phase time data; detecting a brightness peak value according to phase time data to obtain a tip echo, calculating a phase gradient in a neighborhood by using a fixed window to generate a stable domain data set, calculating a spatial range according to a stable domain, extracting a phase change signal along with time, and completing frequency domain dominant frequency extraction and period analysis to generate a period consistent region; according to the method, the continuous image phases are extracted, the time sequence is combined, the needle point recognition stability is enhanced, the echo region is restrained through the brightness peak value and the phase gradient, and the accuracy of positioning is improved. Position judgment is enhanced through spatial range and period analysis, and the guiding precision is improved by combining a three-dimensional distance and a symbol sequence.

Systems and methods for controlling the delivery of energy for thermal ablation. The apparatus may include: a conductive member comprising an array of conductive filaments; a power source configured to supply current to the conductive / resistive member in multiple electrical pulses; and processing circuitry coupled to the power source. The processing circuitry is configured to control the power source current value to be greater than or equal to a first current density and less than or equal to a second current density, and to control the pulse length to be greater than or equal to the first pulse length and less than the second pulse length, and to control the power source current value to have a third current density at a first time and a fourth current density at a second time.

This invention relates to a composite high and low temperature thermal ablation system, and pertains to the field of ablation technology. The composite high and low temperature thermal ablation system of this invention adjusts the pressure of the working fluid storage tank by controlling the number and diameter of the ablation needles connected in the pipeline, and adjusts the opening of the phase separation valve to maintain the phase separation valve at the target temperature. This allows for rapid cooling with minimal consumption of working fluid, regardless of the combination of ablation needles.

The invention provides a combined ablating agent based on spontaneous heating and a preparation method and application thereof, and belongs to the technical field of medical materials. The LipoCA provided by the invention comprises a lipidosome, and CaO and silver nanoparticles which are wrapped in the lipidosome. In the invention, the lipidosome is used as a permeation barrier, CaO is wrapped in the lipidosome, the contact of CaO with H2O molecules and H < + > in a tumor microenvironment is delayed through a physical isolation effect, so that the exothermic reaction is accurately regulated and controlled, the Ag NPs can destroy a calcium metabolism steady state, induce Ca < 2 + > enrichment in tumors, mediate ROS production and promote cell apoptosis, and the Ag NPs, the CaO and the lipidosome have a synergistic effect, so that an exothermic effect is achieved. The composite material can improve the minimally invasive precise treatment of cancers, effectively avoids thermal burns of adjacent blood vessels and nerves, and has multiple functions of regulating and controlling the exothermic reaction rate, inhibiting thermal diffusion, inducing ROS (reactive oxygen species) generation and occluding blood vessels in tumors so as to enhance the thermal ablation curative effect and anti-tumor treatment.

The utility model discloses a heating instrument for executing thermal ablation in intestinal tracts, and relates to the technical field of medical instruments, the heating instrument comprises a sheath tube, a bag body and a liquid injection tube, an inner tube is arranged in the sheath tube, and a heating electrode and a temperature measuring electrode are arranged in the inner tube; the bag body is arranged on the outer wall of the far end of the sheath tube, a heating wire is arranged in the bag body, spiral electrode connectors are integrally formed at the two ends of the heating wire, and the electrode connectors are wrapped in the sheath tube and fixed to the heating electrode in a multi-point welding mode; the liquid injection tube is arranged at the near end of the sheath tube, a liquid injection channel is formed between the inner tube and the sheath tube, one end of the liquid injection channel is communicated with the liquid injection tube, and the other end of the liquid injection channel is communicated with the bag body. The spiral electrode connectors are arranged at the two ends of the heating wire, multi-point welding is formed, welding is facilitated, and the firmness of connection between the heating wire and the heating electrode can be effectively improved through a plurality of welding positions.

The application provides an integrated flame stabilizer with a boss in a trailing edge cavity, which comprises a flame stabilizer, an oil injection rod, a cooling gas inlet pipe, a trailing edge wing plate and a trailing edge boss. In one aspect, the trailing edge cavity is formed downstream of the rear side plate of the flame stabilizer by the trailing edge wing plate, and the trailing edge boss is arranged on the rear side plate, so that the cooling vortex is formed in the trailing edge cavity by the trailing edge boss, the rear side plate and the cooling gas holes arranged on the trailing edge wing plate, the flame stabilizer is isolated from the backflow area downstream of the flame stabilizer, the heat load of the flame stabilizer is reduced, and the thermal ablation problem is avoided; meanwhile, the cooling method has little influence on the backflow area behind the stabilizer, and the flame stabilizing function of the flame stabilizer is not damaged. In another aspect, the cooling gas can also cool the oil injection rod after entering the inside of the flame stabilizer, so that the coking problem of the oil injection rod is solved.

This invention discloses a microwave ablation electrode, relating to the field of medical device technology. It mainly includes a main needle body, whose working end can release microwave energy to achieve microwave ablation. The main needle body is equipped with a non-working end circulating cooling structure and a working end liquid injection structure. The non-working end circulating cooling structure allows a cooling medium to reach the non-working end of the main needle body to cool the non-working end and surrounding tissue, and also allows for the return flow of the cooling medium. The working end liquid injection structure allows a cooling medium to reach the working end of the main needle body to cool the working end and surrounding tissue, and also allows the cooling medium to be injected into the lesion tissue, absorbing microwave energy to form steam, achieving steam thermal ablation. This invention achieves dual ablation through steam thermal ablation and microwave ablation, improving the ablation effect, reducing the temperature of the working end of the microwave ablation electrode, and increasing the moisture content of the tissue surrounding the working end, thus reducing carbonization of the lesion tissue.

The invention discloses a cryogenic radiofrequency ablation needle and system, and belongs to the technical field of cryoablation, the cryogenic radiofrequency ablation needle comprises a needle head part, an adjusting handle part, a delivery pipe part, a quick connector part, a rewarming temperature measurement ablation plug part and a radiofrequency ablation plug part, the needle head part is connected to the adjusting handle part, and the delivery pipe part is connected to the radiofrequency ablation plug part; the adjusting handle part is used for connecting the needle head part and the conveying pipe part, the quick connector part is connected to the conveying pipe part, and the rewarming temperature measurement ablation plug part is connected with the radio frequency ablation plug part. On the basis of a cryoablation probe of a high-pressure nitrogen throttling freezing technology, the rewarming module and the radio frequency ablation module are added, central control switching of the three modules is achieved, the integrated structure design of the freezing module, the rewarming module and the radio frequency module is achieved, the integrated structure can be used in a multi-module combined mode and can also be used independently, and the cost is reduced. The cold ablation function and the thermal ablation function are mutually complemented.

The invention discloses vein closed cryoablation equipment which comprises a low-temperature coolant circulating system, an adjustable cryoablation catheter and a temperature real-time monitoring feedback system, and is an innovative cryoclosure system provided for treatment of great saphenous varicosity. Based on latest clinical research data and an engineering principle, compared with the existing conventional thermal ablation technology, the vein closing cryoablation equipment has the advantages that a better closing effect can be realized, nerve injury is greatly reduced, and intraoperative pain is relieved.

To provide medical probes. [Solution] A medical probe may include electrodes for ablation, for sensing proximity to tissue, and / or for monitoring electrical signals within the cardiovascular system to identify aberrant-conducting tissue sites causing arrhythmias. The electrodes may be oriented on an end-effector assembly, such as a basket assembly, so that one side of the electrode is positioned to contact the tissue and the opposite side is prevented from contacting the tissue. To enable both efficient energy delivery and high sensitivity for ECG sensing, an impedance-reducing coating may be positioned on the tissue-contact side, and an impedance-increasing coating may be applied to the opposite side. The impedance-increasing coating on an IRE electrode may be thin enough to allow energy to be delivered through the coating during ablation. An RF electrode may have a mass sufficient to carry electrical energy for thermal ablation.

The invention relates to the technical field of pulsed electric fields, and discloses a pulsed electric field ablation system and method. The ablation forceps are provided with a pair of forceps arms capable of being opened and closed, and a bipolar electrode set and a multi-mode sensor are arranged on the clamping faces of the forceps arms. The pulse generator is electrically connected with the bipolar electrode group and the multi-mode sensor, and is configured to output a double-phase pulse waveform to the bipolar electrode group; receiving target tissue electrophysiological characteristic data collected by the multi-modal sensor in real time; pulse parameters are dynamically adjusted based on the electrophysiological characteristic data. According to the pulsed electric field ablation system and method, the problem of thermal damage of radiofrequency ablation to blood vessels can be solved through the non-thermal ablation characteristic of the double-phase pulsed electric field.

The invention discloses an ablation area image segmentation method and system in lung cancer thermal ablation, a medium and equipment. The segmentation method comprises the following steps: constructing a lightweight converter based on in-window self-attention and inter-window self-attention cascading; inputting the image into a lightweight converter, and encoding to obtain a multi-scale feature; performing linear mapping on the multi-scale features to obtain mapping features with the same embedding dimension, enabling the spatial dimensions of the mapping features to be the same by using an up-sampling operation, fusing the mapping features by using a channel superposition operation, and generating a coarse segmentation result by using a convolution module; and after superposing the coarse segmentation result and the image channel, inputting the result into an encoder structure of a convolutional network to obtain a convolutional coding feature, fusing the convolutional coding feature with a multi-scale feature, and performing channel superposition with a decoder feature to generate a fine segmentation result. According to the method, complex image features can be extracted, the robustness is high, and the problem that the global modeling capability of the convolutional network is weak is solved.