145 results about "Tissue necrosis" patented technology

A two piece anastomosis device for attaching two organs together and creating a passage between the organs is disclosed. The anastomosis device has a first tissue clamping ring and a second tissue clamping ring that are brought together to clamp tissue therebetween and cut off the flow of blood to the tissue. The tissue clamping rings are locked together with an adhesive, and over time, causes the clamped tissue to necrose and slough off. The sloughed tissue creates a passageway through the anastomosis device. A method of using the fastener to create a bypass passageway between the stomach and small intestine is disclosed.

A fastener including material meltable at a temperature not likely to produce substantial tissue necrosis of neighboring body tissue, or “bondable material”, is caused to soften or melt by the application of vibratory energy, advantageously including ultrasonic vibratory energy. Vibratory energy is applied using a horn applied to the fastener, and tuned to generate vibratory motion proximate the horn, or at a point distal to the horn, for example at a point along the fastener body, or at the end of the fastener. Melted or softened material of the fastener bonds to a contacting surface, which may be body tissue or another implant. The contacting surface may also include bondable material, softenable or meltable through vibratory energy derived from contact with the fastener. To improve a bond, particularly where dissimilar materials are to be bonded, one or more contacting surfaces is provided with a roughened or porous surface, or a surface including one or more cavities or projections into or onto which softened or melted bondable material may form, bonding once the bondable material has cooled.

A jamming retainer for fixing a ligament in a bone tunnel without excessive sideways pressure on the ligament that may result in tissue necrosis the jamming retainer including a substantially rigid body with a bore or loop for receiving a ligament or tendon and a bore or ring for receiving a suture for towing the jamming retainer and ligament or tendon through a bone tunnel. Once positioned, the jamming retainer is fixed in the bone tunnel with an interference screw.

An implantable devices for the effective elimination of an arrhythmogenic site from the myocardium is presented. By inserting small biocompatible conductors and/or insulators into the heart tissue at the arrhythmogenic site, it is possible to effectively eliminate a portion of the tissue from the electric field and current paths within the heart. The device would act as an alternative to the standard techniques for the removal of tissue from the effective contribution to the hearts electrical action which require the destruction of tissue via energy transfer (RF, microwave, cryogenic, etc.). This device is a significant improvement in the state of the art in that it does not require tissue necrosis.In one preferred embodiment the device is a non conductive helix that is permanently implanted into the heart wall around the arrhythmogenic site. In variations on the embodiment, the structure is wholly or partially conductive, the structure is used as an implantable substrate for anti arrhythmic, inflammatory, or angiogenic pharmacological agents, and the structure is deliverable by a catheter with a disengaging stylet. In other preferred embodiments that may incorporate the same variations, the device is a straight or curved stake, or a group of such stakes that are inserted simultaneously.

Systems and methods are provided for removing fatty tissue underlying a patient's epidermis (e.g., blepharoplasty, brow lifts, eyelid shortening procedures, and the like). These methods include positioning one or more active electrode(s) and one or more return electrode(s) in close proximity to a target site on an external body surface of the patient. A high frequency voltage difference is applied between the active and return electrode(s), and the active electrode(s) are translated across the external body surface to create an incision therein. The bipolar configuration controls the flow of current to within and around the distal end of the probe, which minimizes tissue necrosis and the conduction of current through unwanted paths in the patient. The residual heat from the electrical energy also provides simultaneous hemostasis of severed blood vessels, which increases visualization and improves recovery time for the patient.

The present invention relates to a method for preparing a contact lens-shaped amniotic dressing and a contact lens-shaped amniotic dressing prepared therefrom for treating ocular surface diseases, which does not require the use of sutures or an adhesion material. The inventive contact lens-shaped amniotic dressing is capable of solving the problems associated with suturing an amniotic membrane, e.g., highly delicate surgical techniques of suturing, long surgery time, stitch abscess, granuloma formation, tissue necrosis, and discomfort of patients; and the problems associated with the use of a support, e.g., the elimination of the support by eye blinking, breaking of the support, and discomfort.

An apparatus and method for causing necrosis of tissue and specifically intended for thermal ablation of the uterine cavity to cauterizing the endometrial tissue. The apparatus includes a liquid-tight, liquid filled system having a distal flexible member; a proximal flexible member; and a catheter joining and providing a liquid path between these distal and proximal members. The apparatus further includes a pressurizable pneumatic chamber into which the proximal flexible member is inserted and a means to controllably heat the contents of the pneumatic chamber. The system operates to: first withdraw substantially all of the liquid into the proximal flexible member contained within the pressurizable pneumatic chamber; second to heat this liquid to a temperature such that it can cause tissue necrosis; and third to force the heated liquid from the proximal flexible member into the distal flexible member where it is maintained for a predetermined time and at a predetermined pressure. Where this distal member has been inserted into a uterine cavity or is otherwise is in contact with living tissue, the presence of the heated liquid results in tissue necrosis and cauterization.

An injectable or insertable dosage form comprising a biodisintegrable binder and an ablation agent in a concentration effective to cause tissue necrosis. The injectable dosage form is a solid or semi-solid dosage form. Due to the solid or semi-solid nature of the dosage form, retention at the site of injection or insertion is improved, thereby improving delivery efficiency of the ablation agents within the dosage form and/or reducing the nonspecific tissue damage associated with the dosage form.

A bone cement having a dry component including a large constituent and a small constituent. The small constituent fills a substantial volume of the interstitial spaces between the particles of the large constituent. Therefore, only a second or minor interstitial space is left remaining between the individual particles of the small constituent and the particles of the small constituent and the particles of the large constituent. Therefore, a reduced amount of a polymerizable component need be added to the dry component to form a bone cement. Such a bone cement formulation decreases the exothermic temperature of the bone cement and decreases the possibility of tissue necrosis in the implantation area.

The invention discloses a leg reciprocating massaging wheel chair for a nursing department. The leg reciprocating massaging wheel chair comprises a base plate. The wheel chair is characterized in that a back plate is fixedly connected to the right side of the base plate, driving wheels are rotatably connected to the lower portion of the back plate, a motor base is fixedly connected to the middle of the base plate, a motor is fixedly connected to the position over the motor base, and a first sheave wheel is fixedly connected to the output end of the motor; a seat plate is fixedly connected to the left side of the back plate, the lower end of the seat plate is fixedly connected with the base plate, a first through groove is formed in the left side of the seat plate, and a massaging device is fixedly connected below the seat plate; a longitudinal rotating shaft is rotatably connected to the middle of the base plate. Compared with the prior art, the wheel chair has the advantages that the structure is simple, the cruising ability of a patient sitting on the wheel chair is greatly increased through electric drive, and the patient can move to a farther place; in addition, the massage device can be controlled to massage the leg of the patient, leg rehabilitation of the patient is promoted, and leg tissue necrosis of the patient can be effectively avoided.

A thermotherapy catheter for heat treating the prostate gland includes an O-ring positioned within a chamber between an outer tube and an interior heat generation device guide tube. The O-ring supports a distal end portion of a probe guide tube at a desired acute angle so that a temperature probe can be advanced from the end of the probe guide tube into the prostate gland at a predetermined desired acute angle for calculating tissue heating and tissue necrosis information from temperature sensors located on a distal end of the temperature probe. The O-ring also separates a still liquid chamber from a circulatory flow path so that heated liquid surrounding the generation device is applied effectively to heat the prostate gland, while the circulating cooling fluid effectively removes heat from a feed cable which supplies energy to the heat generation device.

The invention discloses a modeling method of a necrosis caput femoris restoring model based on an umbrella-shaped caput femoris supporter. The modeling method comprises the steps that firstly, a three-dimensional model of a to-be-restored caput femoris is obtained, wherein the NURBS curved surface model of the to-be-restored caput femoris is obtained, the to-be-restored caput femoris is a caput femoris which exists in the thigh tissue necrosis area and is pre-restored by the caput femoris supporter, and the caput femoris supporter is composed of an umbrella-shaped supporter body and a supporting sleeve; secondly, the necrosis area needing to be separated is determined according to the shape of the umbrella-shaped supporter body, and a necrosis caput femoris model is established; thirdly, a caput femoris supporter model is established; fourthly, a necrosis caput femoris implantation model is established, wherein the necrosis caput femoris implantation model with an implantation channel and a three-dimensional model of an implanted bone are established; fifthly, the necrosis caput femoris restoring model is established. The modeling method is simple in step, reasonable in design, convenient to achieve and good in using effect, the restoring model of the caput femoris supporter implanted into the necrosis caput femoris can be easily, conveniently and quickly established, and the quality of the established restoring model is high.

A method and apparatus for measuring pressure buildup in a body compartment that encases muscular tissue. The method includes assessing the body compartment configuration and identifying the effect of pulsatile components on at least one compartment dimension. This process is used in preventing tissue necrosis, and in decisions of whether to perform surgery on the body compartment for prevention of Compartment Syndrome. An apparatus is used for measuring excess pressure in the body compartment having components for imparting ultrasonic waves such as a transducer, placing the transducer to impart the ultrasonic waves, capturing the reflected imparted ultrasonic waves, and converting them to electrical signals, a pulsed phase-locked loop device for assessing a body compartment configuration and producing an output signal, and means for mathematically manipulating the output signal to thereby categorize pressure build-up in the body compartment from the mathematical manipulations.

Prolonged and severe tissue hypoxia results in tissue necrosis in pedicled flaps. We demonstrate the potential of near-infrared spectroscopy for predicting viability of compromised tissue portions. This approach clearly identifies tissue regions with low oxygen supply, and also the severity of this challenge, in a rapid and non-invasive manner, with a high degree of reproducibility. Tissues remaining below a certain hemoglobin oxygen saturation threshold (oxygen saturation index <1) for prolonged periods (>6 h) became increasingly dehydrated, eventually becoming visibly necrotic. Tissues above this threshold (oxygen saturation index >1), despite being significantly hypoxic relative to the pre-elevation saturation values, remained viable over the 72 h post-elevation monitoring period. The magnitude of the drop in tissue oxygen saturation, as observed immediately following surgery, correlated with the final clinical outcome of the flap tissue. These results indicate the potential of near infrared spectroscopy and imaging to monitor tissue oxygenation status and assess tissue viability following reconstructive surgery. Early, nonsubjective detection of poor tissue oxygenation following surgery increases the likelihood that intervention aimed at saving the tissue will be successful.

The present invention provides a method for inducing Fallopian tube blockage as a means for female contraception. The method comprises contacting the inner surface tissue of a Fallopian tube with a silver nitrate bearing substrate, delivering an amount of silver nitrate to the tissue sufficient to induce blockage of the Fallopian tube. Preferably, the substrate is a bead. In one embodiment, at least one silver nitrate bearing bead is introduced through the uterine opening of the Fallopian tube by use of a catheter or other device suitable for manipulating the bead. Alternatively, a plurality of beads can be introduced into the Fallopian tube. In a preferred embodiment, one or more silver nitrate bearing beads are arranged on a string to facilitate later removal of the beads. The method of the present invention delivers an amount of silver nitrate to the tissue sufficient to cause tissue necrosis and blockage of the Fallopian tube. The silver nitrate is delivered to the tissue by the substrate in a controlled and localized manner.

A terramycin injection composition has long pharmacodynamic action time, wherein each unit of the terramycin injection composition contains 30% terramycin free alkali, 2%-3% magnesium compound, 30%-50% 2-ketopyrrolidine, 5%-20% propylene glycol, 5%-20% glycerol formal, 1%-5% moderator and the rest is water for injection. The invention prolongs pharmacodynamic action time of terramycin, decreases possibilities of pain, swelling, tissue stimulation and tissue necrosis at the injection sites of animals and improves stability of terramycin at high temperature.

A process and apparatus for measuring pressure buildup in a body compartment that encases muscular tissue. The method includes assessing the body compartment configuration and identifying the effect of pulsatible components on compartment dimensions and muscle tissue characteristics. This process is used in preventing tissue necrosis, and in decisions of whether to perform surgery on the body compartment for prevention of Compartment Syndrome. An apparatus is used for measuring pressure build-up in the body compartment having components for imparting ultrasonic waves such as a transducer, placing the transducer to impart the ultrasonic waves, capturing the imparted ultrasonic waves, mathematically manipulating the captured ultrasonic waves and categorizing pressure build-up in the body compartment from the mathematical manipulations.

The invention discloses pneumatic automatic hemostasis equipment and a pneumatic automatic hemostasis method. The method includes the steps of starting a timer to compute hemostasis time of a tourniquet acting on a wound surface; controlling a miniature air pump to suck in air via air inlet holes to inflate the tourniquet and acquiring an air pressure value in the tourniquet by an air pressure sensor; when the air pressure value is smaller than a first preset value, continuing controlling the miniature air pump to suck in the air via the air inlet holes to inflate the tourniquet; when the air pressure value is larger than a second preset value, controlling the miniature air pump to deflate the tourniquet via air outlet holes; when the air pressure value is between the first preset value and the second preset value, judging whether the hemostasis time reaches preset time or not; when the hemostasis time reaches the preset time, controlling a loudspeaker to play voice information to inform medical personnel of checking hemostasis conditions of the wound surface. The pneumatic automatic hemostasis equipment and the pneumatic automatic hemostasis method have the advantages that the problems of poor hemostatic effects caused by too high or too low hemostasis pressure of the tourniquet acting on the wound surface and wound tissue necrosis caused by long-time continuous vascular compression can be avoided effectively.