1122 results about "Obstetrics" patented technology

The invention provides a gestational diabetes mellitus dynamic risk assessment method and a gestational diabetes mellitus dynamic risk assessment system, and relates to the technical field of gestational diabetes mellitus risk assessment. The collaborative fluctuation intensity of the three core characteristics is accurately quantified by using a matrix norm, a two-factor decision engine is generated by combining postprandial blood sugar daily mean value change direction marks, a long-term metabolism trend under a gestational week differentiation weight is quantified by using a risk coefficient, and a linkage factor is fused with multi-characteristic collaborative fluctuation and a blood sugar short-term change direction. A blood glucose threshold self-adaptive adjustment algorithm is driven in real time, and a traditional static threshold system is thoroughly broken through; an acute event hard interception network is synchronously established, risk assessment result forced coverage and minute-level monitoring activation are triggered through a linkage factor threshold value, and a mechanical response barrier for acute metabolism decompensation is formed; and finally, dynamic risk assessment of the gestational diabetes mellitus is realized.

The invention relates to gestational weight gain prediction. The disclosed concepts are directed to providing protocols, solutions, concepts, designs, methods and systems related to improved prediction of gestational weight gain (GWG). Specifically, during the early stage of pregnancy (e.g., during the first 30 days of pregnancy, or during the first three months of pregnancy), a data sequence describing the weight of a pregnant subject at least twice a day (e.g., after waking up and before falling asleep) is used to determine the historical GWG curve of the subject. Since the energy balance in pregnancy is defined as energy intake equal to energy expenditure plus dynamic energy storage, a particular GWG prediction model is used to generate historical GWG curves, rather than a universal weight gain model. From the historical GWG curve, a future GWG value of the subject may be predicted. The future GWG value may be used to assess pregnancy risk scores, and / or to generate lifestyle recommendations for the subject.

The invention relates to the field of disease animal model construction, and particularly discloses a postmenopausal osteoporosis and knee osteoarthritis co-disease animal model construction method which comprises the following steps: selecting a female animal as an experimental subject; the selected female animals are injected with a GnRH agonist, meanwhile, low-calcium feed feeding and oxidative stress stimulation are conducted, and feeding is conducted for a preset time; detecting bone mineral density and bone trabecula parameters of the fed female animals, and screening qualified female animals meeting set standards; performing meniscus tearing operation on the qualified female animal, and implanting sustained release microspheres loaded with inflammatory factors at the torn part during the operation; carrying out weight-bearing training on the female animal after the operation, and continuing for a set time length; and performing health detection on the female animals at different time points. According to the method, through multi-factor collaborative induction of the PMOP, minimally invasive construction of the KOA and multi-dimensional health detection, accurate simulation of a co-disease pathological process and clinical characteristics is realized, and the authenticity and stability of the model are improved.

The present invention relates to the field of biomedical technology, and more specifically to a method and system for assisting in predicting the risk of premature birth during pregnancy. The method comprises obtaining the physical data and delivery cycles of historical pregnant women, determining the degree of premature birth of the historical pregnant women based on the delivery cycles, and determining the degree of premature birth correlation of different types of physical data of the historical pregnant women based on the differences in the degree of premature birth between different historical pregnant women and the differences in the deviation changes of the same type of physical data during each physical examination. The historical pregnant women are clustered based on the deviation time differences of the same type of physical data between different historical pregnant women, and the overall correlation of each type of physical data is determined based on the number of pregnant women in the cluster and the degree of premature birth correlation of the corresponding type of physical data, thereby screening out the physical data of the target type. A premature birth prediction model is constructed based on the physical data of the target type during different physical examinations of the historical pregnant women to perform premature birth prediction. The present invention effectively improves the accuracy of premature birth prediction.

A kit comprising at least three male condoms, and at least three wearable constriction devices that are physically separate from the condoms. The male condoms are individually packaged in separate compartments, and, the wearable constriction devices are packaged together in a single compartment that is separate from the three male condom compartments. Alternatively, the male condoms are individually packaged in separate compartments, and, the wearable constriction devices are packaged individually in separate compartments that are also separate from the three male condom compartments.

The invention relates to the technical field of puerpera diet management, in particular to a postpartum diet management system and method. The server comprises a data acquisition module, a dimension extraction module, an evaluation module, a diet customization module, a baby data acquisition module and a diet optimization module; wherein the infant data acquisition module is used for monitoring physical state data of an infant born by a puerpera in real time at the first time after the puerpera is postpartum; the judgment module is used for determining the to-be-supplemented nutrient elements missed by the infant and the corresponding missing content according to the body state data corresponding to the infant in each time period; and the diet optimization module is used for optimizing the basic diet scheme according to the basic diet scheme corresponding to each time period of the lying-in woman and the to-be-supplemented nutrient elements and the deficiency content required by the baby born by the lying-in woman in each time period to form a diet optimization scheme.

The invention discloses an in-vitro fertilization-based method and system for predicting the cumulative live productivity of multiple complete cycles, and the method comprises the steps: obtaining clinical data, embryo information and pregnancy follow-up visit data of a patient, and screening and preprocessing a sample in combination with a collection and discharge standard; feature variables are extracted before treatment, after treatment and at the early stage of pregnancy, an optimal set is determined, and key factors influencing live birth at all stages are accurately captured; after the nonlinear variables are processed by the RCS, a pre-treatment / post-treatment COX regression model and a Logistic regression model are adaptively constructed, and the prediction precision is improved by fitting data characteristics; and meanwhile, by evaluating the iterative optimization model, the variable weight is visually displayed by using a Nomogram graph after the model is qualified. The method can accurately predict the multi-cycle cumulative live productivity, assists a doctor in formulating a personalized scheme, helps a patient to reasonably plan treatment, reduces the time and economic burden of blind treatment, and has clinical practical value and benefits of the patient.

The invention discloses an endometrium sampler, which relates to the technical field of medical instruments and is technically characterized by comprising a protective sleeve, a movable tube, a brush rod, a top bead, bristles and a handle, the protective sleeve and the movable pipe are both of a hollow tubular structure, and the movable pipe is arranged in the protective sleeve and can move in the axial direction of the protective sleeve. The brush rod is arranged in the movable pipe, one end of the brush rod is fixedly connected with the handle, and the other end of the brush rod is fixedly connected with the top bead. The section, close to the top bead, of the brush rod is a brush rod front end; the bristles are attached to the front end of the brush rod and incline towards the top bead, and the top bead is of a semi-surrounding cover-shaped structure. During sampling operation, the handle is rotated to drive the front end of the brush rod to rotate, so that the bristles cover an inverted pear-shaped uterine cavity area; after the bristles finish sampling, the movable pipe is controlled to move towards the top bead, so that the bristles are folded and protected by the movable pipe; the sampling efficiency, the sample integrity and the diagnosis accuracy can be improved.

The utility model provides an artificial insemination tube assembly, which belongs to the technical field of insemination tubes and comprises a storage tube, a push rod and an annular air bag, the push rod and the annular air bag are arranged on the storage tube, a feeding tube is arranged on the side wall of one end of the storage tube, and a seminiferous duct is mounted at one end of the storage tube. According to the insemination device, the annular air bag arranged on the outer side of the seminiferous duct expands while insemination is conducted, it is guaranteed that the device is fixed, meanwhile, the situation that semen flows back after insemination is effectively prevented, and then the probability of pregnancy is improved, meanwhile, two one-way valves are installed on the two sides of the annular air bag, and after the annular air bag completely abuts against the inner wall of a uterine cavity, the two one-way valves are closed. When the device is taken out, the other one-way valve is forced to be opened and closed to supplement air into the annular air bag from the outside in the subsequent process of taking out the device, so that the push plug is convenient to move to the initial position, and the safety of the device is improved. The subsequent addition and use of the seminal fluid are convenient.

The invention discloses a dairy cow timed insemination method for controlling ovulation time and improving embryo implantation rate, and relates to the technical field of dairy cow breeding. The problems that follicles on ovaries of postpartum cows are not synchronous in development, ovulation time cannot be accurately regulated and controlled, and embryonic development regulation and control after fertilization are lacked are solved. The method mainly comprises the following steps: three times of gonadotropin releasing hormone injection, two times of cloprostenol sodium injection, gonadotropin releasing hormone injection, luteinizing hormone releasing hormone A3 injection, timed artificial semen deposition, and VADE mixed liquid injection. GnRH is used for actively regulating follicular development, 95% or more of the dairy cows are synchronized after 2-3 rounds of starting, then timing insemination is performed, the conception rate of the postpartum dairy cows can be remarkably increased, compared with the prior art, the pretreatment time is short, the synchronous ovulation rate and conception rate of the dairy cows can be increased, the calving interval is shortened, and the survival rate of the dairy cows is increased. The economic benefit of the pasture is obviously increased, and the breeding management level can be improved on the basis.

The utility model relates to a breast pump. The breast pump comprises a floating assembly and a detection assembly. When milk is loaded in the milk storage assembly, at least part of the floating assembly floats on the liquid level of the milk in the milk storage assembly; the detection assembly is used for detecting position information of the floating assembly floating on the milk liquid surface. In the milk sucking process of the breast pump, the height of the milk liquid level in the milk storage assembly is increased along with increase of the amount of milk in the milk storage assembly, the height of the floating assembly floating on the milk liquid level changes, then the floating assembly gets close to or away from the detection assembly under guiding of the guiding piece, detection data of the detection assembly is changed, and the detection accuracy of the breast pump is improved. Therefore, the milk level height and the milk amount in the milk storage assembly are calculated according to data detected by the detection assembly.

The present invention relates to a process for determining pregnancy and / or a pregnancy stage of an ungulate from its feces.

The invention relates to the technical field of medical detection, in particular to an endocrine hypertension screening method based on immunological analysis, which comprises the following steps: collecting a random urine sample, removing interferents by using a composite nano adsorbent, and synchronously detecting hormones such as aldosterone, methoxyadrenaline and cortisol and metabolites thereof by using a high-throughput immunity analyzer; integrating detection data based on a dynamic threshold algorithm to generate a screening report, carrying out weighted scoring on positive samples in combination with clinical features, screening high-risk candidate samples, carrying out 24-hour urine retest on the high-risk samples, and if a retest result is still positive, carrying out referral treatment to a specialized department for disease cause definite diagnosis; according to the method, the technical problems of complex sample treatment, low multi-step efficiency and high false positive rate in the prior art are solved, efficient and accurate screening of endocrine hypertension is realized, and reliable support is provided for early diagnosis and targeted treatment.

The invention discloses a structural variation molecular marker located on a pig chromosome 7 and related to the lactation ability of a sow. The structural variation molecular marker is a DNA (deoxyribonucleic acid) fragment which is inserted between the 112024896 bp site and the 112024896 bp site on a chromosome 7 of an international pig reference genome 11.1 version, wherein the nucleotide sequence of the DNA fragment is shown as SEQ ID NO: 1; the genotype of the gene is T / T, T / INS and INS / INS. The structural variation molecular marker provided by the invention obviously influences the total weight gain character and the lactation ability character of the 7-day-old sow, and by breeding the pig with the structural variation molecular marker genotype of T / T, the lactation ability of the sow can be obviously improved, and the survival rate and the weaning weight of piglets are increased.

The utility model relates to a sputum excretion vest which comprises a vest body, a sputum excretion mechanism and a control host. The inner side of the vest body is covered with a plurality of air bags communicated with one another, one air bag is connected with an inflation connector, and the inflation connector is externally connected with inflation equipment; the sputum excretion mechanism comprises a front plate, a rear plate and two side plates, the front plate and the rear plate are detachably connected, the two side plates are connected to the two sides of the front plate and the two sides of the rear plate respectively, a plurality of ultrasonic probes are arranged on the inner sides of the front plate and the two side plates in an array mode respectively, and a plurality of vibration modules are arranged on the inner sides of the front plate, the rear plate and the two side plates in an array mode respectively. After a patient wears the vest body, the air bag is inflated through inflation equipment, the ultrasonic probes and the vibration modules are attached to the body of the patient, then the multiple ultrasonic probes are started to detect different parts of the lungs of the patient, and when the area where a certain ultrasonic probe is located detects secreta in the lungs, the vibration intensity of the vibration modules in the corresponding area is adjusted; the vibration sputum excretion treatment is more accurate, and the sputum excretion efficiency is higher.

The present disclosure relates to the field of livestock farming, and specifically provides a feeding method for gilts in batch for promoting onset of puberty and alleviating estrus disorder of gilts, which is aiming at an industrial problem that a large number of gilts are culled due to delayed puberty onset or estrus disorder. The method includes: feeding, prior to onset of puberty for gilts with vitamin A combined with lactic acid; and performing, subsequent to the puberty onset of gilts, estrus synchronization treatment and insemination treatment on the gilts. By applying vitamin A combined with lactic acid, the present disclosure alleviates the delayed puberty onset or estrus disorder of the gilts, reduces the feeding duration and feeding cost of the gilts, facilitates synchronous estrus treatment of the gilts.

The invention provides a calprotectin and slgA combined judgment child digestive state evaluation method and system, and relates to the technical field of data detection.The method comprises the steps that the age of a target child is collected, baseline calprotectin and baseline slgA are configured, and a baseline error coefficient is obtained; collecting body characteristics of the target child and a feeding characteristic sequence in a recent preset time range, configuring a physical sign correction coefficient and a feeding correction coefficient, and correcting to obtain a corrected baseline error coefficient; performing calprotectin and slgA fluctuation prediction according to the feeding characteristic sequence to obtain predicted fluctuation calprotectin and predicted fluctuation slgA, and calculating actual calprotectin and actual slgA; and calculating the fluctuation coefficient of predicted fluctuation calprotectin and predicted fluctuation slgA and the fluctuation coefficient of baseline calprotectin and baseline slgA, calculating to obtain data confidence, labeling, and evaluating the digestive state of children. The technical problem that in the prior art, the accuracy of child digestion state evaluation results is insufficient is solved.

The present disclosure provides a system for testing a health status of a female vagina, including: a collecting element for collecting a female vaginal secretion, wherein the collecting element covers an external surface of a vagina instead of entering the vagina, and is capable of absorbing the vaginal secretion; and a testing element for testing an analyte in the collected vaginal secretion or a property of the analyte to assess a health status of the vagina based on a test result obtained by the testing element.

The invention relates to the field of medical biology, and discloses a construction method and device of a bipolar disorder experimental animal model and application, the construction method comprises the following steps: selecting a healthy experimental animal to carry out environmental adaptation feeding before modeling, then carrying out sleep deprivation stimulation for 3-5 days continuously, and carrying out sleep deprivation stimulation for 15-18 hours continuously and 6-9 hours for rest every day so as to freely eat and feed water; and after the sleep deprivation stimulation is finished, evaluating the surface validity of the disease model for the experimental animal by adopting behavioral test. The construction method provided by the invention is simple to operate and easy to repeat, can better simulate the disease of a clinical bipolar disorder patient, and provides a new model normal form for pathogenesis research and clinical drug screening of the bipolar disorder, and the disease model can be maintained for a long time.

The invention relates to a regulation and control method for synchronous eclosion of middle and later-stage pupae of a silkworm cross variety, and belongs to the technical field of silkworm improved variety breeding. The method aims at solving the problems that existing strong low-temperature inhibition causes pupa physiological injury and synchronous regulation and control in the middle and later periods are insufficient. According to the technical scheme, after cocoons are cut and pupae are identified in the middle stage of pupa body development, female and male pupa forms are observed every day, quantitative scoring is conducted, and comprehensive development scores of two groups are calculated and compared; therefore, differentiated temperature protection is performed on male pupa groups which develop quickly or slowly, and meanwhile, the residual development time difference of the two parties is estimated according to a pre-established development progress comparison table. When the time difference exceeds a set threshold value, physical stimulation is applied to the lagging party, and if the lagging party enters a key window before eclosion, a nutritional agent is synchronously sprayed and supplemented; and after the development of the two parties reaches the standard, differential photosensitive management is executed to trigger synchronous eclosion. The method is mainly used for improving eclosion synchronism and health degree of pupae in silkworm seed production, so that silkworm egg quality is improved.

The invention discloses a gestational diabetes mellitus early prediction method, a gestational diabetes mellitus early prediction system and a computer readable medium, and the method comprises the steps: obtaining pregnant woman sample data used for researching GDM early prediction, the pregnant woman sample data for researching the early prediction of the GDM comprises a plurality of basic clinical characteristics of each pregnant woman before 16 weeks of pregnancy, a plurality of biomarkers related to the pathogenesis of the GDM before 16 weeks of pregnancy, and a diagnosis result whether the biomarkers are GDM or not; screening a plurality of basic clinical features and a plurality of biomarkers in the obtained pregnant woman sample data to obtain basic clinical features and biomarkers with the highest GDM prediction value; and performing GDM prediction on the pregnant woman which is insufficient for 16 weeks of pregnancy by using the basic clinical features and the biomarkers with the highest GDM prediction value, so as to obtain a prediction result that GDM appears or does not appear in 24-28 weeks of pregnancy. According to the method, the GDM high-risk crowd can be predicted in the early stage of pregnancy, the GDM high-risk crowd is intervened, and the occurrence risk of bad outcomes is reduced.

The invention discloses a pregnant sow feed for increasing birth weight of piglets and improving placenta inflammation of sows, and relates to the technical field of biology. The pregnant sow feed comprises a lysozyme oligomer and a basic ration. The pregnant sow feed for increasing birth weight of piglets and improving placenta inflammation of sows provided by the invention is used for dynamically feeding sows in the pregnancy stage, meets the nutrition and energy requirements of the sows from the late pregnancy stage to delivery, and is fed for several times two days before delivery, so that the dystocia condition of the sows can be relieved, the stillbirth rate can be effectively reduced, and the survival rate of the sows is increased. The lysozyme content in colostrum and serum is increased, the anti-inflammatory factor expression of placenta is obviously promoted, the birth weight of piglets is obviously increased, the stillbirth rate is reduced, and the reproductive performance of sows is improved.

1. The name of the product under this design: Portable Breast Milk Cooling Cup (BW01). 2. Purpose of this product: This product is used to keep beverages hot or cold. 3. The key design point of this appearance design product lies in the overall shape of the product. 4. The picture or photo that best illustrates the key points of the design: 3D image of component 1. 5. Other situations that require explanation Other explanations: The portable breast milk cooling cup (BW01) includes component 1, the insulation cup body, component 2, the insulation cup liner, and component 2, the insulation cup liner is detachable.

The invention provides a biomarker for predicting the preeclampsia risk, application of the biomarker and a method for detecting whether an object has the preeclampsia risk or not. According to the method for detecting whether the object has the preeclampsia risk, preeclampsia risk prediction is carried out on all pregnant women in the early and middle stages of pregnancy, whether preeclampsia high-risk groups exist or not is not distinguished, and risk prediction can be carried out before symptoms occur; different types of free RNA in blood are associated with preeclampsia, the biomarker is used for constructing a preeclampsia prediction model in at least 300 samples, and the specificity of the preeclampsia prediction model during pregnancy can be improved to 85% or above.

The present application discloses a gene point mutation mouse model construction method, comprising: by taking T274M mutation on Kcnq2 Exon6 as a target, designing sgRNA and ssODN; selecting a female mouse of a set week age as an ovum donor, injecting a certain dose of serum gonadotropin and human chorionic gonadotropin into the abdominal cavity of the female mouse, then mating the female mouse with a mating male mouse, and collecting zygotes of the mated female mouse; injecting Cas9 protein, ssODN and sgRNA into the pronuclei of the zygotes by means of a microinjection technique, transplanting the zygotes obtained after injection into the ampulla of the fallopian tube of a surrogate female mouse, and obtaining a neonatal mouse after the pregnant female mouse gives birth; respectively designing a pair of identification primers F1, R1 at two ends of a mutation site on the basis of a Kcnq2 gene point mutation site, identifying the neonatal mouse, and screening out a Kcnq2T274M / + point mutant mouse in which T274M mutation is successfully knocked.

A physiological indicator for a pregnant mammal and / or her fetus may be used to augment and / or personalize a fetal oximetry model to the pregnant mammal, the fetus, and / or the pregnant mammal / fetus pair. Light transmission data that corresponds to and / or represents a composite of light that passes through the pregnant mammal's abdomen and the fetus may be received and input into the augmented fetal in vivo fetal oximetry model. An output from the augmented fetal in vivo fetal oximetry model that includes an indication of an oximetry value and / or wellness for the fetus may be generated and / or received.

The present application relates to a terminal device for blood sugar management during pregnancy and its cloud server, the terminal device collects physiological data and blood sugar data of a target user including the gestation period, the cloud server obtains a plurality of blood sugar data of reference users from a plurality of terminal devices and forms an overall reference data set in a manner associated with gestational age, the cloud server calculates basic statistical indicators for each group in the overall reference data set, combines the specific percentile position of the user's blood sugar data in its own group distribution, judges the current blood sugar state of the user by comparing the user's blood sugar data with the preset healthy blood sugar range, and generates a graded diet suggestion accordingly, the diet suggestion optimizes the diet structure of the target user by selecting food categories with different GI values; the terminal device receives and visually displays personalized diet suggestions matching the blood sugar status of the target user to the target user.

The present invention addresses the problem of specifically clarifying the effects on a fertilized egg when 5-ALA is administered to a human female suffering from infertility, and constructing a more effective means for treating infertility through the suppression of chromosomal abnormalities. It has been confirmed that, when 5-ALA is ingested in combination with a drug therapy that is generally performed in the treatment of female infertility, the rate of chromosome aneuploidy in a fertilized egg or the like is significantly reduced, and the qualitative improvement of an embryo through improvement of the stability of the chromosomes is expected.

This invention relates to the field of beauty and skincare, and discloses an automated system and method for detecting semen quality, comprising: a morphological defect rate calculation module for calculating the morphological defect rate corresponding to a target semen sample; a dysfunctional sperm identification module for identifying dysfunctional sperm in the target semen sample; a reproductive function scoring module for evaluating the reproductive function score corresponding to the target semen sample; a dynamic motility potential scoring module for configuring a suitable culture medium for the target semen sample, culturing the target semen sample in the suitable culture medium, recording the sperm viability baseline parameters during the culture process, calculating the sperm survival rate of the target semen sample, and evaluating the dynamic motility potential score corresponding to the target semen sample; and a semen quality analysis module for generating a semen quality analysis report corresponding to the target semen sample. This invention can improve the accuracy of semen quality detection.

Bone plates are disclosed for veterinary uses. For example, the bone plates could be utilized for repairing medial patellar luxation in animals, such as canines, felines, or equines, for example. The bone plates may include various features for better accommodating the anatomy and native tissue structure of the proximal tibia of the animal.