605 results about "Obstetrics" patented technology

The invention discloses an in-vitro fertilization-based method and system for predicting the cumulative live productivity of multiple complete cycles, and the method comprises the steps: obtaining clinical data, embryo information and pregnancy follow-up visit data of a patient, and screening and preprocessing a sample in combination with a collection and discharge standard; feature variables are extracted before treatment, after treatment and at the early stage of pregnancy, an optimal set is determined, and key factors influencing live birth at all stages are accurately captured; after the nonlinear variables are processed by the RCS, a pre-treatment / post-treatment COX regression model and a Logistic regression model are adaptively constructed, and the prediction precision is improved by fitting data characteristics; and meanwhile, by evaluating the iterative optimization model, the variable weight is visually displayed by using a Nomogram graph after the model is qualified. The method can accurately predict the multi-cycle cumulative live productivity, assists a doctor in formulating a personalized scheme, helps a patient to reasonably plan treatment, reduces the time and economic burden of blind treatment, and has clinical practical value and benefits of the patient.

The utility model provides an artificial insemination tube assembly, which belongs to the technical field of insemination tubes and comprises a storage tube, a push rod and an annular air bag, the push rod and the annular air bag are arranged on the storage tube, a feeding tube is arranged on the side wall of one end of the storage tube, and a seminiferous duct is mounted at one end of the storage tube. According to the insemination device, the annular air bag arranged on the outer side of the seminiferous duct expands while insemination is conducted, it is guaranteed that the device is fixed, meanwhile, the situation that semen flows back after insemination is effectively prevented, and then the probability of pregnancy is improved, meanwhile, two one-way valves are installed on the two sides of the annular air bag, and after the annular air bag completely abuts against the inner wall of a uterine cavity, the two one-way valves are closed. When the device is taken out, the other one-way valve is forced to be opened and closed to supplement air into the annular air bag from the outside in the subsequent process of taking out the device, so that the push plug is convenient to move to the initial position, and the safety of the device is improved. The subsequent addition and use of the seminal fluid are convenient.

The present invention relates to a process for determining pregnancy and / or a pregnancy stage of an ungulate from its feces.

The invention discloses a structural variation molecular marker located on a pig chromosome 7 and related to the lactation ability of a sow. The structural variation molecular marker is a DNA (deoxyribonucleic acid) fragment which is inserted between the 112024896 bp site and the 112024896 bp site on a chromosome 7 of an international pig reference genome 11.1 version, wherein the nucleotide sequence of the DNA fragment is shown as SEQ ID NO: 1; the genotype of the gene is T / T, T / INS and INS / INS. The structural variation molecular marker provided by the invention obviously influences the total weight gain character and the lactation ability character of the 7-day-old sow, and by breeding the pig with the structural variation molecular marker genotype of T / T, the lactation ability of the sow can be obviously improved, and the survival rate and the weaning weight of piglets are increased.

The utility model relates to a sputum excretion vest which comprises a vest body, a sputum excretion mechanism and a control host. The inner side of the vest body is covered with a plurality of air bags communicated with one another, one air bag is connected with an inflation connector, and the inflation connector is externally connected with inflation equipment; the sputum excretion mechanism comprises a front plate, a rear plate and two side plates, the front plate and the rear plate are detachably connected, the two side plates are connected to the two sides of the front plate and the two sides of the rear plate respectively, a plurality of ultrasonic probes are arranged on the inner sides of the front plate and the two side plates in an array mode respectively, and a plurality of vibration modules are arranged on the inner sides of the front plate, the rear plate and the two side plates in an array mode respectively. After a patient wears the vest body, the air bag is inflated through inflation equipment, the ultrasonic probes and the vibration modules are attached to the body of the patient, then the multiple ultrasonic probes are started to detect different parts of the lungs of the patient, and when the area where a certain ultrasonic probe is located detects secreta in the lungs, the vibration intensity of the vibration modules in the corresponding area is adjusted; the vibration sputum excretion treatment is more accurate, and the sputum excretion efficiency is higher.

The invention provides a calprotectin and slgA combined judgment child digestive state evaluation method and system, and relates to the technical field of data detection.The method comprises the steps that the age of a target child is collected, baseline calprotectin and baseline slgA are configured, and a baseline error coefficient is obtained; collecting body characteristics of the target child and a feeding characteristic sequence in a recent preset time range, configuring a physical sign correction coefficient and a feeding correction coefficient, and correcting to obtain a corrected baseline error coefficient; performing calprotectin and slgA fluctuation prediction according to the feeding characteristic sequence to obtain predicted fluctuation calprotectin and predicted fluctuation slgA, and calculating actual calprotectin and actual slgA; and calculating the fluctuation coefficient of predicted fluctuation calprotectin and predicted fluctuation slgA and the fluctuation coefficient of baseline calprotectin and baseline slgA, calculating to obtain data confidence, labeling, and evaluating the digestive state of children. The technical problem that in the prior art, the accuracy of child digestion state evaluation results is insufficient is solved.

The present disclosure provides a system for testing a health status of a female vagina, including: a collecting element for collecting a female vaginal secretion, wherein the collecting element covers an external surface of a vagina instead of entering the vagina, and is capable of absorbing the vaginal secretion; and a testing element for testing an analyte in the collected vaginal secretion or a property of the analyte to assess a health status of the vagina based on a test result obtained by the testing element.

The invention relates to a regulation and control method for synchronous eclosion of middle and later-stage pupae of a silkworm cross variety, and belongs to the technical field of silkworm improved variety breeding. The method aims at solving the problems that existing strong low-temperature inhibition causes pupa physiological injury and synchronous regulation and control in the middle and later periods are insufficient. According to the technical scheme, after cocoons are cut and pupae are identified in the middle stage of pupa body development, female and male pupa forms are observed every day, quantitative scoring is conducted, and comprehensive development scores of two groups are calculated and compared; therefore, differentiated temperature protection is performed on male pupa groups which develop quickly or slowly, and meanwhile, the residual development time difference of the two parties is estimated according to a pre-established development progress comparison table. When the time difference exceeds a set threshold value, physical stimulation is applied to the lagging party, and if the lagging party enters a key window before eclosion, a nutritional agent is synchronously sprayed and supplemented; and after the development of the two parties reaches the standard, differential photosensitive management is executed to trigger synchronous eclosion. The method is mainly used for improving eclosion synchronism and health degree of pupae in silkworm seed production, so that silkworm egg quality is improved.

A physiological indicator for a pregnant mammal and / or her fetus may be used to augment and / or personalize a fetal oximetry model to the pregnant mammal, the fetus, and / or the pregnant mammal / fetus pair. Light transmission data that corresponds to and / or represents a composite of light that passes through the pregnant mammal's abdomen and the fetus may be received and input into the augmented fetal in vivo fetal oximetry model. An output from the augmented fetal in vivo fetal oximetry model that includes an indication of an oximetry value and / or wellness for the fetus may be generated and / or received.

The present application relates to a terminal device for blood sugar management during pregnancy and its cloud server, the terminal device collects physiological data and blood sugar data of a target user including the gestation period, the cloud server obtains a plurality of blood sugar data of reference users from a plurality of terminal devices and forms an overall reference data set in a manner associated with gestational age, the cloud server calculates basic statistical indicators for each group in the overall reference data set, combines the specific percentile position of the user's blood sugar data in its own group distribution, judges the current blood sugar state of the user by comparing the user's blood sugar data with the preset healthy blood sugar range, and generates a graded diet suggestion accordingly, the diet suggestion optimizes the diet structure of the target user by selecting food categories with different GI values; the terminal device receives and visually displays personalized diet suggestions matching the blood sugar status of the target user to the target user.

The present invention addresses the problem of specifically clarifying the effects on a fertilized egg when 5-ALA is administered to a human female suffering from infertility, and constructing a more effective means for treating infertility through the suppression of chromosomal abnormalities. It has been confirmed that, when 5-ALA is ingested in combination with a drug therapy that is generally performed in the treatment of female infertility, the rate of chromosome aneuploidy in a fertilized egg or the like is significantly reduced, and the qualitative improvement of an embryo through improvement of the stability of the chromosomes is expected.

Bone plates are disclosed for veterinary uses. For example, the bone plates could be utilized for repairing medial patellar luxation in animals, such as canines, felines, or equines, for example. The bone plates may include various features for better accommodating the anatomy and native tissue structure of the proximal tibia of the animal.

1. Name of the product in this design: Abdominal Massager. 2. Purpose of this design: For abdominal massage. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention belongs to the technical field of underwear, and discloses a connecting buckle, lactation underwear and a single-hand unbuckling method of the lactation underwear. The first buckle body has a connecting state or an unbuckling state relative to the second buckle body; a first magnetic part is arranged on the first buckle body, a second magnetic part is arranged on the second buckle body, and the first buckle body is connected with the second buckle body through magnetic attraction matching of the first magnetic part and the second magnetic part; the first buckle body is provided with a first sliding channel; the second buckle body is provided with a sliding part; when the second buckle body is in a connecting state relative to the first buckle body, the sliding part is limited in the first sliding channel, and when the second buckle body is in a releasing state relative to the first buckle body, the sliding part is located outside the first sliding channel. The connecting buckle can be unlocked in a sliding mode according to using habits of pregnant women, and operation convenience is improved.

The invention belongs to the field of animal model construction, and particularly relates to application of an NFATC2IP gene knockout mouse model. Experiments prove that after the NFATC2IP gene is knocked out, the mouse has the characteristic changes of ovarian weight reduction, volume reduction, estrus cycle disorder, fertility reduction, AMH reduction, FSH increase and the like. It is indicated that the NFATC2IP gene is a key factor for maintaining ovarian reserve and endocrine balance, and an NFATC2IP gene knockout mouse can be used for revealing the occurrence mechanism of ovarian dysfunction and can also be used for screening of novel ovarian protection drugs, research of a hormone regulation mechanism and discovery and verification of biomarkers.

The invention relates to the technical field of animal husbandry, in particular to a synchronous oestrus-timing insemination method suitable for cattle, which comprises the following steps: firstly, performing intramuscular injection of PG (cloprostenol sodium) at different time points after calving to promote uterine recovery and luteolysis and lay a synchronous oestrus foundation; the method comprises the key steps that GnRH (gonadotropin release hormone) is given through intramuscular injection on the 43rd day, the 53rd day, the 60th day and the 69th day, pituitary is promoted to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH), collection and screening of follicles are guided, follicle maturation is promoted, the oestrus uncovering rate and the oestrus conception rate are increased, a melatonin implant is implanted in a subcutaneous implantation mode on the 63rd day, and the melatonin implant is implanted in a subcutaneous implantation mode on the 63rd day. The synthesis of ovarian hormones is promoted by regulating the hypothalamus-pituitary-gonad axis, the secretion of follicle cell factors and maturation promoting factors is promoted, the development of granular cells is promoted, and the maturation of oocytes is promoted. According to the method, the pregnancy rate of a double-synchronization-timing insemination scheme which is most widely used in a large-scale dairy cow breeding pasture at present can be remarkably increased, and feasible technical support is provided for success of increasing the breeding efficiency of cows.

The invention discloses a timed insemination method for improving the pregnancy rate and the lambing rate of sheep, and belongs to the technical field of livestock breeding. In order to solve the problem that the pregnancy rate of existing sheep is unstable during regular insemination, the method comprises the steps that a progesterone sponge suppository is embedded in the vagina of a healthy and reproductive ewe on the 0th day, and meanwhile 25 g of luteinizing hormone is injected in an intramuscular mode to release hormone A3; removing the thrombus on the 12th day, and performing intramuscular injection of 400IU of pregnant mare serum gonadotropin at the same time; and after the suppository is removed, insemination is carried out on the cervix orifice of the ewe with ram semen diluted at the ratio of 1: (5-8) in 52h and 64h respectively. According to the method, ovarian activities of the ewes are regulated and controlled, the estrus synchronism and the ovulation rate are improved, tests show that the pregnancy rate reaches 81.6%, the lambing rate is 1.14, compared with a conventional method, the pregnancy rate and the lambing rate of the sheep are remarkably improved, and development of the sheep industry is promoted.

The utility model discloses a glucometer with a containing structure. The glucometer comprises a glucometer body and a containing assembly. The storage assembly is integrated on the back face of the glucometer body, space utilization is optimized, portability and use efficiency of equipment are improved, the requirement for additionally carrying an accessory bag is avoided, the whole blood glucose monitoring system is more compact and integrated, and cost is reduced. The storage box is ingeniously divided into three independent areas including the test paper cavity, the acupuncture needle cavity and the cotton swab cavity through the design of the partition plates in the storage box, classified storage of different accessories is ensured, the possibility of disorder or loss is reduced, meanwhile, the accessories are protected against damage, and the problem that test paper and blood taking needles are needed during blood glucose testing, and the blood glucose testing cost is reduced is solved. The problems that an existing glucometer is not provided with a containing structure, test paper and a blood taking needle are generally stored independently, and therefore an operator is inconvenient to carry and use the glucometer, and certain limitation exists are solved.

The invention provides a sugar fat disease death risk prediction method and system based on NHANES data, and the method comprises the steps: obtaining the fasting blood glucose FPG and glycosylated hemoglobin HbA1c clinical detection data of a sugar fat disease patient, and calculating an SHR value through a formula; based on the data of the NHANES database, SHR total cause bilateral critical values of total cause death rate and cardiovascular death rate, SHR cardiovascular bilateral critical values and SHR cancer unilateral critical values of cancer death rate are obtained; and comparing the SHR value with an SHR total cause double-side critical value, an SHR cardiovascular double-side critical value and an SHR cancer single-side critical value of the cancer death rate, and carrying out risk layering and evaluation. The biochemical aging acceleration index has a prediction effect on the diabetes death risk, and KDMAgeAccel significantly intermediates the death risk caused by SHR.

A method for determining for a female a time interval for using contraception is disclosed, the method comprising receiving in a processor (11), from a sensor system (22) of a wearable device (2) of the female, physiological data of the female, generating cycle phase probabilities of the female being in one or more cycle phases of her menstrual cycle on a given day, by use of a machine learning model and the physiological data, determining the time interval for using contraception using the physiological data, the cycle phase probabilities, and pre-determined cycle phase probability thresholds, and generating a message for the female comprising the time interval for using contraception.

The invention provides a computer-implemented method for predicting and assessing a health risk parameter, such as the risk of diabetes, in particular gestational diabetes and / or preeclampsia, of a woman based on at least one pregnancy-related parameter, the method comprising the steps of: if the pregnancy-related parameter satisfies a first condition; if so, providing an assessment of the health risk parameter using a first machine learning model (1); providing an assessment of the health risk parameter using a second machine learning model (2) if the pregnancy-related parameter satisfies a second condition; and the health risk parameters are made available.

Provided are methods of contraception using as a first line combined oral contraceptive (COC), a COC composition comprising nomegestrol acetate (NOMAC) and estradiol or an ester thereof. Said COC compositions are associated with a lower risk of venous thromboembolism (VTE) as compared to other CHCs. The compositions may also be used in methods of treatment in women having conditions linked to menstruation and / or fertility.

The present invention relates to a composition comprising an estetrol component and drospirenone for use in treating unscheduled bleeding and spotting in an adolescent female subject. The invention also encompasses associated uses and methods of contraception as well as improving health-related quality of life and alleviating menstrual symptoms in adolescent subjects.

The invention provides an in-vitro induction and purification method for Giardia lamblia cysts. The induction method is characterized in that Giardia lamblia trophozoite is cultured in a TYI-S-33 culture medium containing pulvis fellis suis to obtain the Giardia lamblia cysts. According to the in-vitro induction method for the Giardia lancea cysts, the pig gall powder is added into the TYI-S-33 culture medium to induce the Giardia lancea trophozoite, and it is found that compared with common ox gall powder, the proportion of converting the Giardia lancea trophozoite into the cysts can be remarkably increased, and the generation rate of the induced cysts stably reaches 50%; according to the giardia lamblia cyst purification method disclosed by the invention, protease K is utilized for purification, so that pure cysts can be obtained, long-term stability and activity can be maintained, and the cysts can be stably stored for several weeks to several months at 2-8 DEG C and can be prepared into giardia lamblia cyst standard substances; the method is used for method verification, quality control, disinfection efficiency research, filtration efficiency evaluation and the like.

The present disclosure provides a microscopic insemination support device having a simple configuration. The present disclosure relates to a microscopic insemination support device that supports microscopic insemination in which sperm held by a sperm injection tool is injected into an egg held by an egg holding device. The microscopic insemination support device comprises an acquisition unit configured to acquire information including a relative positional relationship between the sperm injection tool and the egg, and a control unit configured to, on the basis of the information acquired by the acquisition unit, control movement of a stage on which the egg holding device is disposed so as to perform microscopic insemination by injecting sperm into the egg.

The utility model relates to a capsule dosing device for rhesus monkeys, which comprises a thick tube and a thin tube, the thin tube is movably mounted in the thick tube in a penetrating manner, and a claw-shaped clamp is arranged at the bottom of the thick tube; the claw-shaped clamp comprises mounting blocks, the mounting blocks are fixedly mounted on the left inner wall and the right inner wall of the thick pipe correspondingly, first springs are fixedly mounted at the bottoms of the two mounting blocks correspondingly, a movable block is fixedly mounted between the bottoms of the two first springs, and a connecting rod is movably mounted at the bottom of the movable block; and adjusting plates are movably mounted at the bottoms of the connecting rods. The capsule administration device for the rhesus monkey can prevent the rhesus monkey from crushing the capsule to influence the accuracy of the administration amount and the drug absorption, so that the success rate of capsule administration can reach 100%, the test quality is ensured, and effective reference is provided for clinical medication; and moreover, the possibility that the teeth of the rhesus monkey hurt people during capsule administration can be effectively avoided, and the safety of people is guaranteed to the greatest extent.

An automated method for assessing the ZP binding capacity of sperm from morphological characteristics of sperm in assisted reproduction using deep learning is disclosed. The invention also provides a method for predicting fertilization success based on ZP binding capacity of sperm in clinical assisted reproduction.