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78 results about "Predictive factor" patented technology

Predictive factor. A characteristic of a patient that indicates a greater or lesser likelihood of responding to a specific treatment regimen.

Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids

A method for diagnosing or differentially diagnosing a cancer characterized by the presence of cancer cells in the pleural fluid of a mammalian subject, the method comprising contacting a sample of pleural fluid of the subject with colloidal magnetic particles coupled to a ligand which binds to a determinant on a cancer cell, but does not bind above a baseline threshold to other cellular and non-cellular components in pleural fluid; subjecting the pleural fluid-magnetic particle mixture to a magnetic field to produce a cell fraction enriched in ligand coupled-magnetic particle-bound cancer cells, if present in the pleural fluid; and analyzing the enriched fraction for the number of cancer cells in the pleural fluid. In certain aspects, this method involves preparing the pleural fluids for the above-noted method steps by, e.g., dilution of unprocessed pleural fluid. In certain aspect, the pleural fluid is subjected to the diagnostic method within 24 hours of withdrawal from the subject. This method has advantages to present diagnostic procedures for identifying malignant pleural effusions. The tumor cells present in pleural fluid can be characterized with cellular and molecular markers to determine prognostic and predictive factors.
Owner:JANSSEN DIAGNOSTICS LLC

Method for drying cut tobacco and device for predicting moisture content of outlet cut tobacco

ActiveCN108720069AStable cigarette qualityTobacco preparationTobacco treatmentEngineeringMoisture
The invention belongs to the field of tobacco manufacturing and relates to a method for drying cut tobacco. The method comprises the following steps: acquiring predictive factors, wherein the predictive factors comprise preset moisture content of finished cut tobacco, real-time determined data of temperature and humidity in production places and moisture content of blended cut tobacco; inputting the predictive factors into a prediction model so as to obtain a predicted value of the moisture content of the outlet cut tobacco in a cut tobacco drying process; and adjusting process parameters of the cut tobacco drying process according to the predicted value of the moisture content of the outlet cut tobacco in the cut tobacco drying process, wherein the prediction model is established according to historical production data of the finished cut tobacco of multiple batches, and the historical production data comprises the moisture content of the finished cut tobacco, historical determined data of the temperature and humidity in production places, the moisture content of the blended cut tobacco and moisture content of the outlet cut tobacco in the cut tobacco drying process. The inventionfurther relates to a device for predicting moisture content of outlet cut tobacco in the cut tobacco drying process. According to the method disclosed by the invention, the moisture content of the outlet cut tobacco in the cut tobacco drying process is controlled, so that the moisture content of the finished cut tobacco reaches a design value and is kept stable, and the stable cigarette quality is further ensured.
Owner:CHINA TOBACCO FUJIAN IND

Sea wave significant wave height long-term trend prediction method based on reanalysis data

The invention relates to a sea wave significant wave height long-term trend prediction method based on reanalysis data. The sea wave significant wave height long-term trend prediction method is characterized by comprising the steps that (1) weather forecast data of an ERA-Interim reanalysis data set at each time frequency are collected, (2) coordinates of all lattice points are obtained, (3) SLP anomaly and standard deviation are calculated, (4) principal component analysis of the SLP anomaly is conducted, (5) Box-Cox transformation is conducted on sea area data, (6) a predictive factor of sea wave significant wave height is calculated, (7) the standard deviation of the significant wave height and the predictive factor is calculated, (8) the predictive factor is applied into a prediction model, (9) a significant wave height lagged value is applied into the model, (10) SLP field prediction on the basis of EOF is carried out, (11) predictive factor optimization selection is conducted, (12) the sea wave significant wave height is predicted through the model, (13) the prediction level is evaluated, (14) the sea wave significant wave height long-term trend is calculated, and (15) a significant wave height long-term trend chart is drawn. According to the sea wave significant wave height long-term trend prediction method based on the reanalysis data, the significant wave height long-term trend of multiple time frequencies can be predicted, and accuracy is high.
Owner:HOHAI UNIV

Neck anastomosis esophagus cancer resection surgery part infection risk predicting scoring and system

The invention belongs to the technical field of a surgery part infection risk predicating scoring and a system based on independent danger factors. Particularly the invention relates to a risk predicting evaluation scoring method for neck anastomosis esophagus cancer resection surgery part infection and a system thereof. According to the independent danger factors which are firstly screened, an infection predicting model is established. According to an assignment score which is generated by a formula, the influence of the danger factors to a final result-surgery part infection can be more visually presented, thereby facilitating clinical early prediction and evaluation to possibility of surgery part infection after the surgery. Individualized infection risk evaluation supplies a basis forkey disposition of an infection preventing measure. The content of the invention is not reported in China and other countries. Through data statistics analysis, the independent predicting factors forneck anastomosis esophagus cancer resection surgery part infection are screened. A mathematical model is used for establishing the predicting scoring system for the surgery infection risks, thereby laying a certain basis for individually predicting the surgery part infection, and supplying guidance for clinical early intervention measure application.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Method and computer program product for predicting and minimizing future behavioral health-related hospital admissions

ActiveUS8190451B2Facilitates proactive interventionMedical simulationMedical data miningCvd riskComorbidity
An accurate predictive model that identifies the patient / members within the healthcare system at high risk of hospital admission for a wide range of morbidities, or co-morbidities, and that allows subsequent intervention to manage those patients identified as high risk to an acceptable level. There is a further need for such a predictive model that focuses on specific groupings of conditions, e.g., behavioral health predictive modeling. There is also a need for a method that provides for intervention to manage the risk to the identified patients / members. One embodiment of the present invention discloses and claims a method of high-risk patient identification and management. In one aspect, the inventive method may comprise compiling a listing including all individuals with any primary behavioral health diagnosis over a specified time period; merging the listing with at least one data source to extract at least one behavioral health-related predictive factor; generating, based on at least one predictive model, a predictive output comprising the probability that the individuals listed will require a future behavioral health-related hospital admission; identifying the high-risk individuals from the predictive model output; and intervening with the high risk members to identify and modify, to the extent possible, the risk factors that place the member at high risk.
Owner:GROUP HEALTH PLAN

Long-term rainfall prediction model construction method, long-term rainfall prediction method and long-term rainfall prediction device

The invention discloses a long-term rainfall prediction model construction method, a long-term rainfall prediction method and a long-term rainfall prediction device. The construction method comprises the following steps: acquiring a sample set; screening explanatory variables in the sample set based on an error discovery rate control method of multi-hypothesis testing and a random forest model to obtain predictive factors influencing precipitation in corresponding months of the next year; and carrying out random forest modeling according to the prediction factors influencing the precipitation in the corresponding month of the next year and the precipitation in the corresponding month of the next year, and training to obtain a long-term precipitation prediction model of the precipitation in the corresponding month. According to the long-term rainfall prediction model construction method, the long-term rainfall prediction method and the long-term rainfall prediction device provided by the invention, variable screening can be optimized from an experience-dependent method to a data-dependent method, the problem of false positive error rate of a random forest method during empirical variable screening is improved, and the accuracy and reliability of model prediction can be effectively improved.
Owner:CHINA THREE GORGES CORPORATION

Flotilli-2 as target in screening nasopharyngeal carcinoma metastasis inhibiting drugs and application of Flotilli-2

The invention belongs to the fields of functions and applications of gene and protein, and relates to Flotilli-2 as a target in screening nasopharyngeal carcinoma metastasis inhibiting drugs and an application of the Flotillin-2. The invention provides a target for screening nasopharyngeal carcinoma metastasis inhibiting drugs, wherein the target is Flotillin-2. The invention also provides an application of the Flotillin-2 as a drug target in screening nasopharyngeal carcinoma metastasis inhibiting drugs. The invention also provides a drug for inhibiting nasopharyngeal carcinoma metastasis, which takes the Flotillin-2 as a target. The drug is siRNA of Flotillin-2. The invention discloses the relation between the Flotillin-2 (Flot2) and a TGF-beta signal path in nasopharyngeal carcinoma as well as effects of the Flot2 and the TGF-beta signal path in nasopharyngeal carcinoma metastasis for the first time. In the nasopharyngeal carcinoma, the Flot2 is an independent predictive factor of patient poor prognosis, an important component of the TGF-beta signal path and an indispensable important node in a process of stimulating emergency medical treatment (EMT). Silent Flot2 may become one of important means of resisting EMT caused by TGF-beta. Therefore, the invention provides a theoretical foundation and a clinical base for researching a new target and a new strategy in inhibiting nasopharyngeal carcinoma metastasis.
Owner:NANFANG HOSPITAL OF SOUTHERN MEDICAL UNIV

A long-term trend prediction method for significant wave height of ocean waves based on reanalysis data

The invention relates to a sea wave significant wave height long-term trend prediction method based on reanalysis data. The sea wave significant wave height long-term trend prediction method is characterized by comprising the steps that (1) weather forecast data of an ERA-Interim reanalysis data set at each time frequency are collected, (2) coordinates of all lattice points are obtained, (3) SLP anomaly and standard deviation are calculated, (4) principal component analysis of the SLP anomaly is conducted, (5) Box-Cox transformation is conducted on sea area data, (6) a predictive factor of sea wave significant wave height is calculated, (7) the standard deviation of the significant wave height and the predictive factor is calculated, (8) the predictive factor is applied into a prediction model, (9) a significant wave height lagged value is applied into the model, (10) SLP field prediction on the basis of EOF is carried out, (11) predictive factor optimization selection is conducted, (12) the sea wave significant wave height is predicted through the model, (13) the prediction level is evaluated, (14) the sea wave significant wave height long-term trend is calculated, and (15) a significant wave height long-term trend chart is drawn. According to the sea wave significant wave height long-term trend prediction method based on the reanalysis data, the significant wave height long-term trend of multiple time frequencies can be predicted, and accuracy is high.
Owner:HOHAI UNIV
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