The invention discloses a processing method of a whole-grain vegetarian meal replacement powder having functions of losing weight and relaxing bowels; 15-25 parts of whole-grain sorghum flour, 15-25 parts of unpolished rice flour, 10-20 parts of coix seed flour and 20-30 parts of oat flour are used as main raw materials, 5-20 parts of red bean flour and 5-20 parts of lenticchia flour are added, 3-5 parts of letinous edodes fibers, 3-5 parts of a red date powder, 3-5 pars of inulin, 2-4 parts of gynostemma pentaphylla, 1-2 parts of a bifidobacterium bifidum freeze-dried powder and 0.5-1 part of a folium sennae extract are added auxiliarily, 10-20 parts of a celery-sweet potato juice is used for adjusting the water content, and then the raw materials are processed by the following steps: medium-temperature pressure difference expansion; gas fluidization precise water control; micro-particle homogenization processing; closed taste locking and aroma enhancement; mixed seasoning; and collection packaging and the like. The weight-losing bowel-relaxing vegetarian meal replacement powder has good dispersing property, and the water solubility index and the water absorption index after the vegetarian meal powder is brewed are both high. For ensuring maximization preservation of functional ingredients, the product has the characteristic of being brewed into paste in warm water with the temperature of 40 DEG C-60 DEG C, and has uniform texture and no caking (agglomeration), precipitation or delamination phenomenon after being brewed. The meal replacement paste tastes sweet, and is delicate, smooth and palatable in mouthfeel. The meal replacement powder can significantly reduce the ill falling risk of weight-losing bowel-relaxing people, and can assist to medicines for eating. The product presents the unique flavor and taste of baked grains, has a faint fragrance of vegetables, and has no bad smell. The product treated by the process has the shelf life reaching more than or equal to 1 year after vacuum or nitrogen-filling package.