50 results about "Two-photon absorption" patented technology

The application belongs to the technical field of semiconductor power devices, and particularly discloses a method for laser stripping gallium oxide. The method is characterized in that a super-short pulse laser with a predetermined wavelength is irradiated into the gallium oxide, and a two-photon absorption process occurs when the laser is focused at a position with a specific thickness from the surface. The high temperature generated in the process causes thermal decomposition of the gallium oxide, thereby achieving the purpose of stripping the gallium oxide. Compared with the traditional substrate cutting technology, the stripping method can significantly reduce the cutting consumption of the gallium oxide substrate, and the cut substrate can be reused after polishing, which helps to reduce the manufacturing cost of the gallium oxide device.

The invention discloses a 2-micron wave band silicon-based germanium surface incidence type high-speed high-responsivity photoelectric detector, which comprises a p-type doped silicon layer 005, the upper surface of the p-type doped silicon layer 005 is provided with a germanium absorption region 006 and a cathode electrode 011, and the cathode electrode 011 surrounds the germanium absorption region 006; the middle part of the germanium absorption area 006 is provided with a porous resonant cavity array 009, the upper surface of the germanium absorption area 006 is provided with an anode electrode 012, and the anode electrode 012 surrounds the porous resonant cavity array 009. Through direct incidence, a 2-micron optical signal output by an external laser source is input into a germanium absorption region, the optical signal in the germanium absorption region is transversely propagated in the germanium absorption region due to a porous resonant cavity array structure, is finally limited and concentrated in the germanium absorption region, and generates two-photon absorption in the germanium absorption region to generate a free electron hole pair; oriented movement is carried out under external bias voltage loaded through the electrodes, and light current is formed.

The utility model discloses a notch filter adjusting structure which comprises an optical sleeve, a filter is coaxially installed in the optical sleeve in a sliding fit mode, a knob is arranged on the outer side of the optical sleeve, a rotary adapter is installed on the end portion of the knob, the rotary adapter is connected with the filter in a matched mode, and the filter can be adjusted by rotating the knob. And the filter can be driven to move along the axial direction of the optical sleeve by rotating the adapter. The device is simple in structure and convenient to adjust, and the signal-to-noise ratio and the detection precision of the two-photon absorption spectrum are improved.

The application discloses a self-correlation instrument based on gallium oxide two-photon absorption ultraviolet femtosecond laser pulse width measurement, and belongs to the technical field of photoelectric regulation and control. The self-correlation instrument comprises a laser generating device, an optical delay system and a self-correlation signal acquisition device. The laser generating device is used for generating a first light beam and a second light beam. The optical delay system is connected with the laser generating device and is used for changing the time when the first light beam and the second light beam reach a sample to be measured. The self-correlation signal acquisition device is used for receiving two-photon photoelectric conversion signal change data caused by the sample to be measured being irradiated by the first light beam and the second light beam in sequence, and obtaining a self-correlation signal based on the two-photon photoelectric conversion signal change data. The application makes full use of the ultraviolet wave band absorption characteristics of gallium oxide to prepare an ultraviolet detector, and uses the self-correlation method to measure the photoelectric conversion signal generated by two-photon absorption of the gallium oxide ultraviolet detector to measure the pulse width of the 350-450 nm near-ultraviolet wave band femtosecond laser.

The present invention discloses an N^N^N type terpyridine platinum complex, its preparation method, and application. The present invention relates to the technical field of fluorescent probe material preparation, and specifically to an N^N^N type terpyridine platinum complex, its preparation method, and application. The present invention mixes 4'-(3,4-bisethoxyphenyl)-2,2':6',2''-terpyridine (S1) with K2PtCl4, adds a halogenated hydrocarbon solvent and an alcohol solvent, and conducts a heating reaction. After the reaction, the solvent is removed by reduced pressure distillation, and column chromatography is used for purification to obtain an N^N^N type terpyridine platinum complex. The preparation method of the N^N^N type terpyridine platinum complex of the present invention has readily available raw materials, a simple reaction process, and can be industrially produced. It has specific targeting to lysosomes, low cytotoxicity, and good two-photon absorption activity, and has good application prospects in lysosomal analysis and imaging products.

The present invention is directed to a method for printing a micro-scaled or nano-scaled XUV and / or X-ray Diffractive optic (1), including the following steps: a) providing a material (2) with a first component (2a) being photo-sensitive and being polymerizable by two-photon-absorption, b) providing data (3) of a desired geometrical structure (4) of the optic (1) and creating at least one trajectory (8) corresponding to the data (3) of the desired structure (4) of the optic (1), c) providing a high-intensity energy beam (5), in particular a laser beam, wherein the beam (5) comprises a focus (F) having a position being adjustable to a plurality of positions (F1, F2, <, Fp) being coincident with the at least one trajectory (8), d) polymerization of the material (2) by two-photon-absorption at a first position (Fn) of the focus (F), thereby creating a first voxel (vn1n2n3) of the structure (4) of the optic (1), adjusting the position of the focus (F) from the first position (Fn) to a subsequent position (Fn+1) of the focus (F) along the at least one trajectory (8) and repeating step d) at the subsequent position (Fn+1) of the focus (F), wherein a distance (d) between each of the positions (F1, F2, <, Fp) of the focus (F) and at least one of the rest of the positions (F1, F2, <, Fp) of the focus (F) is smaller than a mean diameter (vd) of the voxels produced at these positions with respect to their dimension parallel to the distance (d).

The utility model discloses a shielding measuring device for two-photon spectral absorption, which comprises a shading shell, a collecting port is arranged on the side wall of the shading shell, a target material cavity and a reflecting mirror are arranged in the shading shell, the target material cavity is positioned between the reflecting mirror and the collecting port, and the reflecting mirror is positioned between the collecting port and the target material cavity. A collecting pipeline communicated with the interior of the shading shell is further arranged on the top of the shading shell, a photomultiplier is installed at the upper end of the collecting pipeline, and the collecting pipeline is located over the target material cavity and is perpendicular to the target material cavity. According to the scheme, the influence of external stray light on a result is isolated through a large cavity, and the experimental measurement efficiency is greatly improved; a small cavity is made to cut off the influence of scattered photons of incident light on a result, a light insulation protection measure of a photomultiplier is taken, and meanwhile, the photomultiplier is mounted above a target material cavity, so that the signal-to-noise ratio of a two-photon absorption spectrum is greatly improved.

The invention discloses an iridium complex as well as a preparation method and application thereof, and relates to the technical field of optogenetics. The iridium complex has the following structural formula, X is an anion, Y is selected from an alkane derivative, an ether derivative or an amine derivative, the iridium complex provided by the invention is regular in structure, the central metal atom iridium has excellent fluorescent property, and fluorine atoms and trifluoromethyl groups introduced into the ligand have excellent fluorescent property, so that the fluorescence intensity of the iridium complex is greatly improved. The electron structure and the energy level of the complex are obviously regulated, the photophysical performance of the complex is enhanced, and excellent two-photon absorption capacity is shown, so that the complex has huge application potential in the fields of biological imaging, photodynamic therapy and the like.

The invention belongs to the technical field of mid-infrared imaging, and discloses a mid-infrared two-photon calculation imaging system and method based on pumping space coding, and the method comprises the steps: carrying out the spatial intensity coding of near-infrared pumping light through employing a spatial light modulator; the intensity code of the pump light is mapped into the non-degenerate light by means of the nonlinear effect of the single-pixel detector, the detector outputs the integral intensity value of the non-degenerate signal related to the spatial intensity code, and the two-dimensional information of the object to be detected is reconstructed by combining the correlation algorithm. By means of the non-degenerate two-photon absorption effect of a single-pixel detector material, structural detection of a mid-infrared light field is achieved. Compared with direct modulation in a mid-infrared light field, the method has the advantages that the influence caused by a long-wave diffraction effect is effectively avoided, high-precision coding modulation is realized, and the physical pixel limitation of a traditional mid-infrared detector is effectively broken through. The invention has the technical advantages of high imaging sensitivity, fast time response, high modulation precision, large imaging field of view, wide response band and the like.

This invention discloses a two-photon fluorescent dye, prepared as follows: 6-hydroxy-2-naphthaldehyde reacts with a dihaloalkane under alkaline conditions to obtain a monohaloalkane-based aryl ether, which is then reacted with an aqueous trimethylamine solution to prepare S1; diethyl 4-(4-tolyl)pyridine-2,6-dicarboxylate reacts with N-bromosuccinimide to obtain a brominated product, which is then reacted with triphenylphosphine to prepare S2. After intermediates S1 and S2 react under strongly alkaline conditions, the product is then hydrolyzed to prepare the target product. This dye exhibits good cell membrane permeability, good dispersion in the cytoplasm, preferentially targets organelles in the cytoplasm, is water-soluble, has very low toxicity, and a high two-photon absorption interface, making it suitable for two-photon fluorescence confocal microscopy imaging.

The invention relates to a pulse measurement method based on two-photon absorption, and the method comprises the following steps: S1, selecting perovskite as a medium, and placing the medium on a sample stage of a Michelson interferometer; s2, the light source emits an ultrashort laser pulse to be measured and divides the ultrashort laser pulse into two paths of pulses, one path of pulse passes through the adjustable delay line and then is combined with the other path of pulse in perovskite, and a two-photon absorption signal is generated; and S3, obtaining a two-photon absorption interference autocorrelation curve IAC experiment through the two paths of pulses and the two-photon absorption signal, and reconstructing to obtain complete information of the to-be-measured ultrashort laser pulse by combining the spectral intensity of the to-be-measured ultrashort laser pulse. According to the invention, multi-photon absorption response is taken as a core detection mechanism, so that the technical limitation of traditional non-linear effects depending on second harmonic generation and the like is effectively broken through, the problem that materials such as perovskite and the like do not have second harmonic so that pulse measurement cannot be realized is solved, and measurement of higher sensitivity and wider wave band of ultrafast light pulses is realized.

The invention belongs to the technical field of infrared / terahertz detection, provides a terahertz detector based on microcavity enhanced non-degenerate two-photon absorption, solves the problem that a traditional high-sensitivity terahertz detector needs ultralow-temperature refrigeration, and adopts the technical scheme that the input end of a polarization controller is connected with a pump laser used for generating pump light; the input end of the optical fiber taper is connected with the output end of a polarization controller for adjusting the polarization characteristic of the pump light; the surface of the echo wall mode microcavity is coated with a fluorescent material of quantum dot perovskite, and a terahertz signal to be detected is focused on the fluorescent material through a terahertz focusing lens used for gathering field energy; optically coupling the optical fiber taper and the echo wall mode microcavity; the input end of the optical filter is connected with the output end of the optical fiber taper, and the output end of the optical filter after the non-fluorescent wave band is filtered is connected with a photoelectric detector used for converting light field intensity information generated by fluorescent light waves into electric signals. Terahertz high-sensitivity detection at normal temperature becomes possible.

The invention relates to the technical field of research and development of tumor photodynamic therapy photosensitizers, photothermal therapy photothermal reagents and sonodynamic therapy sonosensitizers, and provides a preparation method and application of a binuclear metal complex of a polythiophene bridging ligand. The invention relates to a ruthenium complex TBLRu3a-TBLRu6a and a ruthenium complex TBLRu3b-TBLRu6b of a polythiophene bridged tri-bidentate ligand, a ruthenium complex TTLRu1-TTLRu12 of a polythiophene bridged bis-tridentate ligand, and an osmium complex TTLOs1-TTLOs6 of a polythiophene bridged bis-tridentate ligand, which are respectively designed and invented by the invention. The invention further relates to a preparation method of the ruthenium complex TBLRu3a-TBLRu6a and the ruthenium complex TBLRu3b-TBLRu6b of the polythiophene bridged tri-bidentate ligand and a preparation method of the ruthenium complex TTLRu1-TTLRu12 of the polythiophene bridged bis-tridentate ligand. The polythiophene bridged metal complex has extremely high stability and excellent two-photon absorption characteristic, has excellent biotoxicity and photothermal conversion capability under the action of infrared exciting light, and can induce A549R cell apoptosis. The polythiophene bridged metal complex provided by the invention is a potential novel two-photon absorption photodynamic therapy photosensitizer, a photothermal therapy photothermal reagent and a sonodynamic therapy sonosensitizer, and has a wide application prospect in photodynamic therapy, photothermal therapy and sonodynamic therapy of tumors.

A method of altering a refractive property of a crosslinked acrylic polymer material by irradiating the material with a high energy pulsed laser beam to change its refractive index. The method is used to alter the refractive property, and hence the optical power, of an implantable intraocular lens after implantation in the patient's eye. In some examples, the wavelength of the laser beam is in the far red and near IR range and the light is absorbed by the crosslinked acrylic polymer via two-photon absorption at high laser pulse energy. The method also includes designing laser beam scan patterns that compensate for effects of multiphone absorption such as a shift in the depth of the laser pulse absorption location, and compensate for effects caused by high laser pulse energy such as thermal lensing. The method can be used to form a Fresnel lens in the optical zone.

The application provides a silicon super-structure surface unit based on Fano resonance and a super-structure surface. The silicon super-structure surface unit based on Fano resonance comprises a unit base and two base protruding ribs. The base protruding ribs are arranged on the side surface of the unit base, and the base protruding ribs extend from the upper surface to the lower surface of the unit base. First base defects are arranged between the two base protruding ribs, and second base defects are arranged on both sides of the two base protruding ribs. The silicon super-structure surface based on Fano resonance comprises a plurality of silicon super-structure surface units based on Fano resonance arranged in an array. Each silicon super-structure surface unit based on Fano resonance is provided with three base defects. The symmetry of the silicon cubic structure is broken by the defects, the weak coupling between the bright and dark modes is induced, the sharp Fano resonance is generated, the large local near-field enhancement is realized, and the two-photon absorption response is greatly enhanced.

The invention provides a near-infrared fluorescence activated protein, a gene containing the near-infrared fluorescence activated protein, an expression box and a using method thereof, and a cell and a kit for generating the near-infrared fluorescence activated protein. A compound formed after the near-infrared fluorescence activated protein is combined with a corresponding fluorescent ligand has strong fluorescence, the fluorescence excitation peak wavelength is 574nm, near-infrared light with the emission peak wavelength is 680nm, and the near-infrared fluorescence activated protein has the advantages of high fluorescence quantum yield, large two-photon absorption cross section and the like, and has the advantage of high signal-to-noise ratio in vitro, living cells and living animals.

The application provides a coumarin and carbazole dipyridine salt type water-soluble two-photon initiator, a preparation method and application thereof, and in particular, a use in the field of laser micro-nano processing technology. In the structural general formula of the two-photon initiator, R1 is selected from hydrogen, C 1‑12 alkyl, C 1‑12 hydroxyalkyl or an ethereal unit with a number of repetitions of 1-12; R2 is selected from methyl, ethyl or isopropyl; and Y is a corresponding anion. The two-photon initiator has a large conjugated structure, and the introduction of the dipyridine salt enables the two-photon initiator to be soluble in water. As an initiator, the two-photon initiator can initiate two-photon photopolymerization in an aqueous phase, and the two-photon absorption cross section is greater than 100 GM, so that the power threshold of two-photon photoinitiation during processing is low, i.e. 25 mW. Therefore, the high initiation activity and low two-photon polymerization threshold of the two-photon initiator enable the two-photon initiator to efficiently initiate two-photon polymerization in an aqueous phase, and the effect of processing three-dimensional hydrogels by using two-photon polymerization is outstanding.

A method for infrared chemical imaging through nondegenerate two-photon absorption includes a step of providing pulsed or continuous wave radiation having pumping photons at near-infrared wavelength and providing pulsed or continuous wave radiation that having mid-infrared photons at a mid-infrared wavelength with peak intensities less than 50 W / cm2. The mid-infrared photons are directed onto a target sample. The method also includes a step of spatially and temporally overlapping the mid-infrared photons with the pumping photons. The mid-infrared photons and the pumping photons are directed onto a camera having an array or matrix of imaging devices. Characteristically, the sum of photon energy for each temporally and spatially overlapping mid-infrared photons and pumping photons is greater than or equal to the bandgap energy.

The invention discloses a hypocrellin derivative with near-infrared II-region two-photon absorption as shown in a formula (I), and a preparation method and application of the hypocrellin derivative. According to the invention, the hypocrellin is modified by simultaneously substituting the 14-site, the 2-site and the 3-site, so that the novel hypocrellin derivative with near-infrared II-region two-photon absorption is obtained. The novel hypocrellin derivative prepared by the invention is in a near-infrared region II (gt; and active oxygen can be efficiently generated under the irradiation of pulse laser (1000 nm). Compared with unmodified hypocrellin, the penetration depth of the hypocrellin in tissues is remarkably enhanced, and the hypocrellin can be used for photodynamic therapy of tumors in deeper layers.

The present invention discloses a two-photon fluorescent probe and its application in sulfatase detection, wherein the structure of the endoplasmic reticulum-targeted two-photon fluorescent probe is shown below: #imgabs0#. The endoplasmic reticulum-targeted two-photon fluorescent probe of the present invention responds to different concentrations of sulfatase, with a detection limit as low as 0.12 U / L and a two-photon absorption cross section of 81 GM. Cytotoxicity tests demonstrate that the probe has low biological toxicity. Confocal fluorescence microscopy imaging demonstrates that the probe can effectively target the endoplasmic reticulum in HeLa cells (localization coefficient of 0.86), making it suitable for fluorescent imaging detection of sulfatase in the endoplasmic reticulum of living cells.

The application discloses an iridium complex and a preparation method and application thereof, and relates to the technical field of optogenetics. The iridium complex has the following structural formula: wherein X is an anion, and Y is selected from alkane derivatives, ether derivatives or amine derivatives. The iridium complex provided by the application has a regular structure, the central metal atom iridium has excellent fluorescence properties, and the fluorine atoms and trifluoromethyl groups introduced in the ligand not only significantly regulate the electronic structure and energy level of the complex, but also enhance the optical physical properties of the complex, and the excellent two-photon absorption capacity is exhibited, which makes the complex have great application potential in the fields of biological imaging and photodynamic therapy.

To provide a material with large two-photon absorption cross-sectional area.SOLUTION: A two-photon absorption material is provided, containing a molecule having a thiolate ligand and a metal thiolate complex bound to a surface of a small atomic cluster nucleus. An element constituting the small atomic cluster nucleus and a metal element constituting the metal thiolate complex are Au, and the small atomic cluster nucleus of the molecule of the metal thiolate complex has an atomic number in a range of 10-56.SELECTED DRAWING: None

This invention discloses a chip-integrated all-optical modulation method based on photogenerated free carriers. The pump light field enters the optical modulator through a directional coupler, generating free carriers through two-photon absorption, which changes the refractive index of the transmission waveguide. The phase of the signal light field changes with the refractive index, achieving effective modulation. This method, based on the relatively mature chip-integrated optical path fabrication process, can be fabricated through a single exposure and etching step. While offering advantages such as high modulation rate, low insertion loss, high mechanical stability, and high fabrication efficiency, it is expected to be widely used in ultra-large-scale chip-integrated optoelectronic systems.

A polymerization initiator molecule, excitable by two photons and capable of generating polymerization-initiating free radicals, includes two branches grafted onto a central phenyl nucleus. Each branch includes an oligomer of oligophenyleneethynylenyl type or oligo-2,5-dihalogenphenyleneethynylenyl type. A photopolymerizable composition, activatable by two-photon absorption, includes a radically polymerizable resin and a photochemically effective amount of a radical photoinitiator system. The photoinitiator system includes at least one initiator molecule as described above. Moreover, a method and an associated device for two-photon three-dimensional printing are disclosed. The method includes transforming a volume of a photopolymerizable composition including at least one initiator molecule. The transformation includes irradiating the volume of composition with an irradiation light source emitting an irradiation signal having a wavelength Lirr of between 1 and 1.5 times, and preferably between 1.1 and 1.25 times, a cut-off wavelength LCutOff of the initiator molecule. Embodiments may apply to submicron-resolution two-photon 3D printing.

The invention relates to the technical field of photoelectric detection, in particular to a photoelectric detector and system based on ferroelectric perovskite non-degenerate two-photon absorption. The photoelectric detector comprises a substrate layer; the metal electrode layer is positioned on the substrate layer; the light absorption layer is located on the substrate layer and is composed of a ferroelectric perovskite thin film; the protective layer is formed by a boron nitride film; the metal electrode layers are located on the two sides of the light absorption layer. The photoelectric detector can perform photoelectric detection by using a ferroelectric perovskite non-degenerate two-photon absorption effect, a detection threshold value is reduced by one order of magnitude, and measurable light current can be generated for weak light without high-peak light power; a built-in electric field generated by spontaneous polarization of the ferroelectric perovskite can effectively separate electron-hole pairs, so that the signal-to-noise ratio and the response speed are greatly improved; and the structure is simple, the cost is low, and high-sensitivity and stable detection on weak light can be realized.

The application discloses a kind of semi-confocal lens, two-photon laser-induced fluorescence system and application, the semi-confocal lens includes inner lens and outer lens;Wherein, inner lens is embedded in the middle of outer lens;The mirror surface diameter of the inner lens is 10-20mm, and focal length is 250-350mm;The mirror surface diameter of the outer lens is 80-120mm, and focal length is 310-450mm.Two-photon laser-induced fluorescence system includes laser, and after laser is reflected by laser reflector, it is focused at the focal point of the inner lens of semi-confocal lens, after two photons are absorbed in the atom of focusing place, transition to higher energy level, then de-excitation and emit photon produce fluorescence, and the fluorescence produced is received by the outer lens of semi-confocal lens, and after being reflected by fluorescence reflector, it is focused by focusing lens and received by photomultiplier tube.The application also provides a kind of two-photon laser-induced fluorescence system in strong background two-photon absorption laser-induced fluorescence hydrogen atom neutral gas density measurement application.

The present disclosure pertains to two-photon microscopy, and specifically to methods and systems for optimizing the performance of entangled two-photon absorption (ETPA) microscopy. An ETPA microscope is described with time delay tunability to optimize the coincidence of entangled photons on a sample. The optimization allows for increased two-photon absorption by the sample, resulting in increased luminescence of the sample. The ETPA microscopy systems and methods described allow for nonlinear imaging using excitation energy intensities six orders of magnitude lower than comparable two-photon absorption microscopy techniques using classical light.

The application discloses a two-photon fluorescent dye containing pyridine dicarboxylic acid units, and a preparation method thereof. The dye has the following preparation method: 6-hydroxy-2-naphthaldehyde reacts with a sulfonic acid lactone under the action of an alkaline substance, or reacts with a dihalogenated hydrocarbon to obtain a monohalogenated hydroxyl aryl ether, and then the monohalogenated hydroxyl aryl ether reacts with a sulfite to prepare S1; 4-(4-methylphenyl) pyridine-2,6-dicarboxylic acid diethyl ester reacts with N-bromosuccinimide to obtain a bromide, and then the bromide reacts with triphenylphosphine to prepare S2; intermediates S1 and S2 react under the action of a strong base, and then hydrolysis is carried out to prepare a target product. The dye has good cell membrane permeability, preferentially targets a cell nucleus, is well dispersed in the cell nucleus, has water solubility, has very low toxicity, has a high two-photon absorption interface, and can be applied to two-photon fluorescence confocal microscopic imaging.

The invention belongs to the technical field of fluorescent probes, and particularly discloses an N-CDs fluorescent probe as well as a preparation method and application thereof, and the fluorescent probe is prepared from p-phenylenediamine and L-tartaric acid by adopting a one-step hydrothermal method. The invention relates to a carbon quantum dot probe which has a two-photon absorption characteristic and can specifically target a cell nucleus and a lipid droplet organelle in a living cell at the same time so as to realize double-color and double-target fluorescence imaging. The probe has important application value in the aspects of long-time dynamic observation of living cells, multi-organelle interaction research and deep tissue imaging.

The invention relates to triaryl boron modified aza [7] helicene derivatives with two-photon absorption and two-state circular polarization luminescence characteristics. The invention belongs to the technical field of organic photoelectric functional materials, and provides an aza [7] helicene derivative with dual-state circular polarization luminescence and two-photon absorption properties. The fluorescent quantum efficiency of pure carbon [7] helicene is remarkably improved, and the double-state CPL and strong TPA characteristics are realized in a single organic molecule.