4095results about "Silicon organic compounds" patented technology

The invention discloses a general KRAS inhibitor, the structure of which is shown as a formula I. In the formula, the definition of each substituent group is shown in the description and claims. The general KRAS inhibitor has the advantages of easily available raw materials, simple synthesis, wide action range and strong effect, and can reduce or avoid the possibility of drug resistance generation. # imgabs0 #

Provided are a new compound capable of forming a surface treatment layer having excellent abrasion resistance, a method for producing the same, a composition and a surface treatment agent which contain said new compound, an article that has a surface treatment layer having excellent abrasion resistance, and a method for producing the same.　This compound is represented by formula (1) or formula (2).　(1): [R1-Q1-(SiR2 2-O)p1]q1-SiR2 q2-Q2-Z1-Si(R3)nL1 3-n (2): L1 3-n(R3)nSi-Z1-Q2-SiR2 2-O-(SiR4 2-O)p2-SiR2 2-Q2-Z1-Si(R3)nL1 3-n Wherein, R1 represents (R11)3Si- or the like, R11 represents a hydrocarbon group or the like, Q1 represents an oxygen atom or the like, R2 represents a hydrocarbon group, R3 represents a hydrocarbon group, R4 represents a hydrocarbon group or the like, p1 represents a number of 0-500, p2 represents a number of 0-500, q1 represents 1-3, q2 represents 0-2, q1+q2 equals 3, Q2 represents a single bond or the like, Z1 represents an alkylene group having 7-100 carbon atoms, L1 represents a hydrolyzable group or the like, and n represents 0-2.

The disclosure relates to a light-emitting device including a first electrode, a second electrode facing the first electrode, and an interlayer disposed between the first electrode and the second electrode and including an emission layer. The interlayer includes a first compound represented by Formula 1 of the specification, a second compound represented by Formula 2 of the specification, and a third compound, which is a blue phosphorescent compound. The disclosure also relates to an electronic apparatus including the light-emitting device.

The invention relates to the technical field of preparation of organic photoelectric materials, in particular to a boron-nitrogen compound with a polynary fused ring, an OLED (Organic Light Emitting Diode) with the compound and an organic light-emitting device with the compound. According to the boron-nitrogen compound disclosed by the invention, through matching of a fused heterocyclic structure and limited groups such as tertiary butyl and naphthenic base, the thermal stability of the compound can be improved, and the boron-nitrogen compound has an excellent luminescence characteristic; the boron-nitrogen compound provided by the invention is used as a light-emitting layer material, so that the organic light-emitting device can effectively have lower driving voltage and maintain the stability of the voltage, and the light-emitting efficiency is improved.

The invention provides a boron-nitrogen heterocyclic compound as well as an intermediate and a preparation method thereof, the boron-nitrogen heterocyclic compound has a structure as shown in a general formula (1), and is prepared by taking compounds as shown in a formula A, a formula B and a formula C as intermediates. Compared with similar carbon skeleton molecules, the boron-nitrogen heterocyclic compound provided by the invention shows an excellent narrow-band luminescence property. The half-peak width of the emission spectrum of the boron-aza compound is as low as 6.4 nm, and meanwhile, the fluorescence quantum yield is as high as 97%.

The invention belongs to the technical field of OLEDs, and provides a polycyclic compound containing triphenyl silicon and a polyalkyl substituent group and an organic electroluminescent device containing the polycyclic compound. The structural general formula of the polycyclic compound is as shown in formula I in the specification. Benzofuran with higher electronegativity is introduced to a ring structure composed of nitrogen atoms and boron atoms, triphenyl silicon is introduced to the para-position of boron, and the synergistic effect of benzofuran and triphenyl silicon can significantly enhance the multiple resonance of a light-emitting core and reduce vibration relaxation. Due to simultaneous use of the benzofuran and the triphenyl silicon, the problems of vibration relaxation increase, spectrum widening and the like caused by introduction of the polyalkyl substituent are remarkably improved, the luminous efficiency of the material is remarkably improved, and the color purity is improved, so that the requirement of BT.2020 wide color gamut display standard on a luminescent spectrum is met. I

The invention discloses an organic silicon cooling liquid and a preparation method thereof, the product has low viscosity and high flash point, and relates to the field of application of single-phase cooling liquid for heat dissipation of heating equipment, and the specific method comprises the following steps: uniformly mixing olefin and a catalyst at 20-30 DEG C, heating to 35-45 DEG C, dropwise adding hydrogen-containing siloxane, and controlling the temperature of the reaction liquid to be in a range of 60-130 DEG C; after adding, continuously stirring; cooling after the reaction is finished, and removing residual olefin to obtain a final product with a general formula of (CH3) 3SiO-[R1R2SiO] nSi (CH3) 3, wherein R1 is an alkyl group ranging from 8 to 16; r2 is a methyl group or a trimethylsiloxy group; n is equal to 1-2. The prepared single-phase organic silicon cooling liquid has the performance of high flash point and low viscosity, is low in surface tension, good in fluidity, more comprehensive in coverage, better in heat dissipation effect, good in compatibility with materials of a data center, free of swelling and other damage with related materials, and safe and long-acting.

The invention belongs to the technical field of pharmaceutical chemical processes, and particularly relates to a preparation method of a penem antibiotic intermediate 4-BMA, which comprises the following steps: adding Zn powder, chlorosilane, aliphatic tertiary amine, zinc salt and 4-AA in a formula (I) into THF (tetrahydrofuran), uniformly stirring, dropwise adding a THF solution of alpha-haloamide with an induction group in a formula (II) for reaction, filtering the reaction solution, removing the zinc powder, and drying to obtain the penem antibiotic intermediate 4-BMA. Extracting the filtrate to obtain a THF phase, washing with an aqueous solution of potassium oxalate, and recovering THF to obtain a formula (III); and carrying out oxidative hydrolysis, sulfur dioxide quenching, sulfur dioxide acid regulation crystallization and recrystallization on the formula (III) to obtain the intermediate 4-BMA. According to the preparation method disclosed by the invention, a zinc salt is used as a catalyst during preparation of the formula (III), potassium oxalate is used for removing residual Zn (II) in a THF phase, SO2 is used for quenching hydrogen peroxide and acid regulation and crystallization of 4-BMA, the oxygenolysis problem of 4-BMA is solved, and the preparation method has the characteristics of greenness, safety and high efficiency, is strong in product competitive advantage and is suitable for industrial production.

A surface treatment agent containing a hydrocarbon-terminal-group-containing compound of the following formula makes it possible to form a cured film that is exceptional in water repellency, slipperiness, dirt removability, and abrasion resistance, particularly steel wool abrasion resistance and wet abrasion resistance. (R1 is a C12-80 monovalent hydrocarbon group that includes a C12 or higher monovalent or divalent linear unsubstituted aliphatic saturated hydrocarbon group and does not contain a hydrocarbon branched structure, R2 is H, a halogen atom, a hydroxyl group, a siloxy group, an -OSi(CH3)3 group, an -OSi(C2H5)3 group, an amino group, an SH group, a monovalent hydrocarbon group, R1, -V-Z-(Y-A)m, or -Y-A, U is a single bond, C, or a trivalent or tetravalent organic group, V is a single bond or a divalent hydrocarbon group, Z is a single bond, C, Si, N, S, or a trivalent to octavalent organic group, Y is a single bond or a divalent hydrocarbon group, A is a monovalent reactive group, k is 0, 1, or 2, and m is 1-7.)

The invention belongs to the technical field of organic light-emitting materials, and relates to a boron-containing polycyclic compound for an organic light-emitting material. According to the invention, aryl or heteroaryl is taken as a center, 2-3 boron atoms are introduced and form covalent bonds with atoms such as N, O, S and Se, and a rigid polycyclic compound is constructed. The compound provided by the invention is a boron-containing polycyclic compound with multiple resonance effects, can realize narrow-spectrum and high-color-purity luminescence, also has efficient TADF characteristics, and significantly improves the performance of OLED devices. Compared with the prior art, the compound has remarkable advantages in the aspects of molecular structure design, photoelectric property regulation and control, application range and the like, provides important technical support for development of new-generation high-performance OLED materials, and has wide market prospects and application potential.

The invention relates to the technical field of preparation of organic photoelectric materials, in particular to a boron-nitrogen compound containing a carbazole group, an OLED with the compound and an organic light-emitting device with the compound. According to the boron-nitrogen compound containing the carbazole group disclosed by the invention, the compound has excellent luminous efficiency and relatively good thermal stability by limiting the combination of an aromatic group, a carbazole structure and a parent nucleus; meanwhile, the boron-nitrogen compound containing the carbazole group provided by the invention is used as a luminescent layer material for a device, so that the organic luminescent device can effectively have lower driving voltage and maintain the stability of the voltage, the luminous efficiency is improved, the service life is obviously prolonged, and the boron-nitrogen compound has a very good application prospect.

The invention discloses a nitrogen-containing heterocyclic compound as well as a pharmaceutical composition and application thereof. The invention provides a nitrogen-containing heterocyclic compound as shown in a formula I, and pharmaceutically acceptable salts, prodrugs, stereoisomers, tautomers or isotope compounds thereof. According to the present invention, the nitrogen-containing heterocyclic compound has good inhibition effects on a variety of mutations such as KRASG12C, KRASG12D, KRASG12V, KRASQ61H and the like, and the wild type cells amplified by KRAS, and is expected to be used for treating and / or preventing a variety of Ras-related diseases. # imgabs0 #

The invention relates to the field of biological medicine, in particular to a compound and a preparation method and application thereof. Particularly, the invention relates to a compound shown in a formula (I) or pharmaceutically acceptable salt, stereoisomer, solvate, isotope labeled compound or polymorphic substance thereof, a preparation method thereof, a pharmaceutical composition containing the compound and application thereof, the compound can be used as a sodion channel inhibitor, has an analgesic effect, and can be used for preparing a sodion channel inhibitor. The compounds of the present application also have a variety of excellent properties. # imgabs0 #

The present disclosure, among other things, provides technologies for synthesis, including reagents and methods for stereoselective synthesis. In some embodiments, the present disclosure provides compounds useful as chiral auxiliaries. In some embodiments, the present disclosure provides reagents and methods for oligonucleotide synthesis. In some embodiments, the present disclosure provides reagents and methods for chirally controlled preparation of oligonucleotides. In some embodiments, technologies of the present disclosure are particularly useful for constructing challenging internucleotidic linkages, providing high yields and stereoselectivity.

A multifunctional organosilicon compound is provided which has the general formula XSi([OSiR2]p-0-SiR2Y)a(R1)3-a— ln the formula, X is selected from H and ethylenically un saturated moieties; each Y independently comprises a functional moiety selected from alkoxysilyl moieties, acryloxy moieties, and epoxide moieties; each R is an independently selected hydrocarbyl group; each R1 is an independently selected hydrocarbyl group; subscript a is 1, 2, or 3; and each subscript b is independently 0, 1, or 2. A method of preparing the multifunctional organosilicon compound is also provided. The method comprises reacting (A) an organosilanol compound and (B) a silane compound having at least two hydrolysable groups. A functionalized siloxane compound prepared from the multifunctional organosilicon compound, a method of preparing the functionalized siloxane compound, and an adhesive comprising the functionalized siloxane compound are also provided.

Provided are organic compounds comprising as the central structure two 6-membered aromatic rings which are bond to each other via a direct bond, wherein a first ring of the two 6-membered aromatic rings comprises at least one nitrogen atom but not more than three nitrogen atoms. Also provided are formulations comprising these organic compounds. Further provided are organic light emitting devices (OLEDs) and related consumer products that utilize these organic compounds.

The present disclosure is directed to DNA-PK inhibitors having the Formula (I), or a pharmaceutically acceptable salt, stereoisomer, solvate, prodrug, or tautomer thereof, methods of preparing the forgoing, and compositions thereof, as well as methods of use for the compounds of Formula (I), in combination with a DNA cutting agent.

The invention discloses an organic electroluminescent material and an organic electroluminescent device and application thereof.The organic electroluminescent material can serve as a functional layer of the organic electroluminescent device, 9-alkyl-9-phenyl-9H-fluorene serves as a parent nucleus and is directly connected with arylamine on the parent nucleus, one side chain of the arylamine is aryl or heteroaryl, the other side chain of the arylamine is 1, 1, 4, 5, 6-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1, 3-tetramethyl-1 Compared with other compounds, the organic electroluminescent material compound disclosed by the invention has the advantages that the transverse electric leakage is small, and the phenomena that adjacent pixels are lightened, transverse crosstalk is generated between adjacent sub-pixels and color display is influenced due to transverse leakage current of the adjacent pixels in a device can be reduced. The organic electroluminescent material is used as a functional layer of the organic electroluminescent device, and the problems that color display is affected and picture display is abnormal due to transverse electric leakage of an OLED display device can be solved.

To provide a coolant which exhibits relatively excellent fluidity even at low temperatures and can be easily handled and stored due to having a high flash point.SOLUTION: This coolant contains an organopolysiloxane represented by formula (1) (wherein R1 moieties are each independently a methyl group or an ethyl group, and n is 2 or 3), and is characterized in that the organopolysiloxane has a kinematic viscosity of 100 mm2 / s or less at -80°C and 300 mm2 / s or less at -100°C.SELECTED DRAWING: None

The invention provides a compound containing a silicon group and an organic electroluminescent device thereof, and particularly relates to the technical field of organic electroluminescent materials. When the compound containing the silicon group is used as a covering layer material, the glass transition temperature is high, the thermal stability and the chemical stability are good, the light transmittance of a device can be improved, aging of the device is delayed, and therefore the service life of the device is effectively prolonged; and the compound has weak metal adsorption capacity, and can effectively inhibit the deposition of a metal electrode material on the surface of a nucleation inhibition layer when being applied to the nucleation inhibition layer, thereby improving the performance of the device. In conclusion, the silicon group-containing compound provided by the invention can be widely applied to the fields of panel display and the like, and has a good development prospect.

The 5-OMe-6-tBu substitution of the indenyl fragment of the C1 symmetric catalyst is crucial to improve the EP molecular weight capability. The catalyst described in this document is also capable of producing other conventional polyolefins such as iPP, PE and EO copolymers. The added capability of high molecular weight EP copolymers can broaden the possibilities of the C1 symmetric system in the fields of RCP and ICP where such capability is required.

Described herein are methods for making alkenyl disiloxanes, comprising combining an alkenyl halosilane with a bis-hydrido terminated alkyl disiloxane and adding the mixture to water, an acidic aqueous solution, or a basic aqueous solution. The ratio of the alkenyl halosilane to the bis-hydrido terminated alkyl disiloxane is about 1:10 to about 10:1. The alkenyl halosilane and bis-hydrido terminated alkyl disiloxane are mixed at about 20° C. to about 45° C. In an example, no organic solvent is present. The reaction product is separated and washed with saturated NaHCO3 solution (e.g., sodium bicarbonate).

The present invention provides an amidinate compound represented by the following general formula (1) or a dimer compound thereof, and a method of producing a thin-film including using the compound as a raw material:where R1 and R2 each independently represent an alkyl group having 1 to 5 carbon atoms, R3 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms, M represents a metal atom or a silicon atom, and “n” represents the valence of the atom represented by M, provided that at least one hydrogen atom of R1 to R3 is substituted with a fluorine atom.

The invention relates to the technical field of organic photoelectric materials, in particular to a luminescent layer material with a spiro structure, a preparation method of the luminescent layer material and an organic electroluminescent device, and the luminescent layer material is a compound with a structure as shown in a formula (I). The synthesis and purification method of the compound is simple and easy to implement, and the compound has excellent photoelectric properties, can be used as an organic light-emitting layer material of an organic light-emitting diode, and is used for preparing the organic light-emitting diode with high external quantum efficiency, low efficiency roll-off and long service life. # imgabs0 #

Disclosed herein are activatable inactive sonosensitizer compounds, referred to as locked sonosensitizer compounds, designed with a detachable stimuli-responsive tether acting as a trigger or safety, as these compounds restore their inherent sonosensitization activity upon the detachment of the tether. The invention further encompasses pharmaceutical compositions comprising the same, offering a strategic approach to sonodynamic therapy, whereas the compounds and compositions are formulated to be administered and applied under favorable conditions, enhancing their efficacy in the context of therapeutic applications, since the therapeutic methods presented herein are more versatile and efficient compared to presently known SDT methods due to the controlled activation of the sonosensitizer.

The invention discloses a distillation and purification method for electronic-grade bis(tert-butylamino)silane, and belongs to the technical field of bis(tert-butylamino)silane purification. The invention uses a distillation-adsorption-re-distillation method to jointly process a crude bis(tert-butylamino)silane product, wherein some low-boiling-point substances can be removed by distillation-light removal treatment, some high-boiling-point substances can be removed by distillation-heavy removal treatment, and metal impurities and phosphorus-containing non-metallic impurities can be removed by adsorption treatment; and impurities existing in the product are further removed by distillation-light removal and distillation-heavy removal treatment, so as to obtain electronic-grade bis(tert-butylamino)silane with a product purity of 99.99%.

The invention discloses a system for purifying trimethylsilane containing dichlorosilane impurities, which comprises a reactive distillation column and a purification distillation column, and also discloses a method for purifying trimethylsilane containing dichlorosilane impurities, which comprises the following steps of: feeding trimethylsilane gas containing dichlorosilane impurities into the reactive distillation column; trimethylsilane gas containing dichlorosilane impurities enters the reaction section to react, the dichlorosilane impurities react to generate silane gas and a material containing tetrachlorosilane impurities, the silane gas is discharged from an exhaust port in the top of the reactive distillation tower, and the material containing tetrachlorosilane impurities enters the purification distillation tower from a discharge port in the bottom of the reactive distillation tower; according to the method disclosed by the invention, dichlorosilane is taken as a raw material, the dichlorosilane is taken as a raw material, the dichlorosilane is rectified in a purification rectifying tower and is collected at a tower top collecting port to obtain the high-purity trimethylsilane, the dichlorosilane impurity in the trimethylsilane can be effectively removed through the method disclosed by the invention, the high-purity trimethylsilane with the purity of 99.99% or above is obtained, the yield is greater than 85%, the process is simple, and the cost is low.

The invention relates to a compound, a composition, an organic optoelectronic device, and a display device. The compound is represented by Chemical Formula 1, where X1 and X2 are each independently NRa, O, S, Se, or Te, any one of R1 to R10 is a group represented by Chemical Formula A, the remaining ones of R1 to R10 and Ra are each independently hydrogen, deuterium, a substituted or unsubstituted C1 to C20 alkyl group, a substituted or unsubstituted C6 to C30 aryl group, a substituted or unsubstituted C2 to C30 heterocyclic group, a substituted or unsubstituted amine group, a substituted or unsubstituted silyl group, a cyano group, or a halogen, and R1 to R10 and Ra are each independently present, or adjacent two of R1 to R10 and Ra are linked to form a ring.