212 results about "Borane" patented technology

A polyfunctional organohydrogensiloxane is prepared using a fluorinated triarylborane Lewis acid as catalyst. The polyfunctional organohydrogensiloxane may be formulated into release coating compositions. Alternatively, the polyfunctional organohydrogensiloxane may be further functionalized with a curable group to form a clustered functional organosiloxane. The clustered functional organosiloxane may be formulated into thermal radical cure adhesive compositions.

The present invention relates to a dental diaphragm copolyester and a preparation method thereof, the preparation method comprises the following steps: 2, 5-furandicarboxylic acid or an ester thereof, aliphatic or alicyclic diol and (2-hydroxy-5-formyl phenyl) diphenylborane are subjected to a reaction to obtain an esterification or ester exchange product; and carrying out condensation polymerization on the esterification or ester exchange product and the stabilizer to prepare the copolyester for the dental diaphragm. 2, 5-furandicarboxylic acid is derived from a renewable biomass resource and meets the requirements of green and sustainable development; compared with terephthalic acid and furan ring structures, the film has higher rigidity and polarity, the yield of hot press molding is improved, the same correction force can be met by a thinner film, the wearing comfort of a patient is improved, and meanwhile stress relaxation is improved; the catalyst perfectly combines strong Lewis acidity, intramolecular stabilization and potential bifunctional activation through structural design, provides possibility for efficient and green synthesis of polyester, avoids use of heavy metal, and is higher in biological safety.

The invention discloses an inorganic-organic hybrid cross-linked network high-toughness material and a preparation method thereof, and belongs to the technical field of engineering material preparation. The high-toughness material is composed of an inorganic phase component and an organic phase component, the inorganic phase component is prepared from 5 to 10 parts of amino modified silicon dioxide nanoring; the organic phase component is prepared from the following components in parts by weight: 90 to 105 parts of polycaprolactone glycol, 14.5 to 16.5 parts of isophorone diisocyanate, 0.8 to 1.5 parts of dibutyltin dilaurate, 4 to 6 parts of bis-catechol borane and 6 to 10 parts of polydopamine nano particles. The fracture performance of the material can reach 20 kJ / m or above and is far higher than-1 kJ / m of a common elastomer and-10 kJ / m of high-toughness hydrogel, and meanwhile the tensile strength of 30 MPa or above is kept. According to the material disclosed by the invention, the dynamic borate bond is utilized, after the material is in contact with a damaged section, efficient self-repairing can be realized after the material is placed at room temperature for 24 hours, and the repairing efficiency is gt; by heating and applying pressure, the whole material can be reshaped through fracture and recombination of the dynamic bonds, and green and sustainable effects are achieved.

The invention relates to a low-expansion moisture-resistant electronic component packaging resin adhesive and a preparation method thereof, and belongs to the technical field of high polymer materials. The resin adhesive comprises the following components: modified resin, phenyl methyl organic silicon resin, epoxy vinyl resin, a dynamic functional curing agent, a microencapsulated dicyandiamide curing agent, perfluorooctyltriethoxysilane, functional filler and the like; the modified resin is obtained by modifying hydrogenated bisphenol A epoxy resin with hydrogen-terminated polydimethylsiloxane and trimethylsiloxy silicate ester, adding a silane coupling agent and mixing; the dynamic function curing agent is obtained by reacting hexamethylenediamine and intermediate powder obtained by reacting 2, 3-dihydroxy benzaldehyde with pinacol borane; the functional filler comprises silicon dioxide and boron nitride which are subjected to surface treatment by a silane coupling agent. The low-expansion and high-moisture-resistance electronic component packaging resin adhesive is prepared from the components according to a specific ratio and a specific method, the components have a synergistic effect and play advantages, and the packaging reliability and the service life of an electronic component are guaranteed.

The invention discloses a preparation method, an intermediate and application of menochromone. The preparation method comprises the following steps: reacting 4-bromopyrrole-2-carboxylic acid with propargylamine to generate 4-bromo-N-propynyl pyrrole-2-formamide; the preparation method comprises the following steps: reacting 4-bromo-N-propinyl pyrrole-2-formamide with pinacol borane to generate a mixture; reacting the mixture with 2-(t-butyloxycarboryl amino)-5-iodo-1H-imidazole to generate (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate, and reacting the (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate with the tert-butyl carbamate; and reacting the (E)-(5-(3-(4-bromo-1H-pyrrole-2-formamido) prop-1-ene-1-yl)-1H-imidazole-2-yl) tert-butyl carbamate with a dioxane hydrochloride solution, so as to generate the menochromone. The invention provides a preparation method of menosin, which is short in synthetic route, simple and convenient to operate, high in product yield and suitable for industrial production.

The invention discloses a preparation method of a copper-palladium alloy loaded nano titanium dioxide semiconductor material as a catalyst for a carbon dioxide reduction reaction. Firstly, alloy nanoparticles are generated through a sol-gel method, the morphology of the nanoparticles is controlled and agglomeration is prevented through oleylamine and oleic acid, and borane-tert-butylamine is added at the temperature of 170 DEG C to regulate and control the sizes of the generated alloy nanoparticles. A series of characterizations prove that the catalyst has a very good particle loading condition, uniform particle distribution and increased reaction active sites, and shows excellent activity when being applied to a carbon dioxide reduction reaction, when the loading capacities of copper and palladium are respectively 1%, the activity of the obtained catalyst is the highest, the methane generation rate can reach 20.23 mol / g / h, and the methane generation rate can reach 20.23 mol / g / h. The selectivity of methane reaches 100%.

The application discloses a catalyst for isocyanate borohydration reaction and a preparation and application method thereof. When the catalyst is used for catalyzing the borohydration reaction of isocyanate and borane to synthesize borate, the catalyst has high catalytic activity, mild reaction conditions (the reaction can be carried out at room temperature), short reaction time, high product yield (≥99%), and the reaction is simple, controllable, and simple in post-treatment.

The present application relates to a kind of catalyst composition and its application in catalytic preparation optically active secondary alcohol, the catalyst composition includes chiral ionic bridged aryloxyalkane rare earth complex and additive, the additive is selected from one or more of pyrimidine, N,N-dicyclohexylmethylamine, 4,4'-dipyridyl.The above-mentioned catalyst composition can be used for synergistically catalyzing asymmetric borohydration of chalcone and its derivatives with pinacol borane, and show high catalytic activity and high enantioselectivity, product yield is as high as 99%, ee value can reach 84%, provide a reliable new way for the efficient, high selective synthesis of optically active secondary alcohol.

The present disclosure relates to methods and apparatuses for depositing metal-containing material on a substrate by a selective deposition process. The method comprises providing a substrate in a reaction chamber, providing a metal alkoxide precursor into the reaction chamber in a vapor phase; and providing a second precursor into the reaction chamber in a vapor phase to form metal-containing material on the substrate. The second precursor according to the disclosure comprises a borane compound and the substrate comprising a first surface and a second surface.

The present application relates to the application of open-cage borane compounds in the preparation of immunosuppressants, belonging to the technical field of biological medicine. The open-cage borane compounds of the present application include nest borane compounds and / or spider web borane compounds, and the pharmaceutically acceptable solvates or pharmaceutically acceptable complexes of the nest borane compounds and the spider web borane compounds. The open-cage boron clusters of the present application have dehydrogenase-like activity, can catalyze the dehydrogenation reaction of hydroxyl-containing organic substrates in a biological system, promote the conversion of NAD(P) + to NAD(P)H, further improve the intracellular oxidation-reduction ratio, induce cell redox stress, and further reshape the metabolic pattern of HSCs from the source, promote the differentiation of immune cells to immunosuppressive phenotype, and play an immunosuppressive role.

The invention discloses a nitrogen-rich energetic ionic salt compound based on bis-(5-aminotetrazole) boron. The nitrogen-rich energetic ionic salt compound comprises bis-(5-aminotetrazole) boric acid guanidine salt (I), bis-(5-aminotetrazole) boric acid aminoguanidine salt (II) and bis-(5-aminotetrazole) borane perchlorate (III), the structural formulas of the compounds are shown as (I)-(III). The compound can be used for mixed explosives and fuel-rich propellants.

The invention relates to the technical field of organic synthetic chemistry, in particular to a preparation method and medical application of selenophosphate promoted by tris (pentafluorophenyl) borane. The preparation method of the selenophosphate ester comprises the following steps: under the action of tris (pentafluorophenyl) borane, taking seleno cyanate ester and phosphate ester as reaction raw materials, and carrying out stirring reaction under a certain temperature condition to obtain the selenophosphate ester compound. The synthesis method is mild in condition, does not need a metal catalyst and an oxidizing agent, and accords with the idea of green chemistry. The method also has the advantages of simplicity in operation, few byproducts, high purity and the like. In-vitro anti-inflammatory experiments prove that the selenophosphate compound disclosed by the invention has remarkable anti-inflammatory activity, can effectively inhibit the generation of inflammatory factors and cell inflammatory response, can be used as an active ingredient of anti-inflammatory drugs, and has a wide clinical application prospect.

The application discloses a kind of efficient adsorption separation method of impurities in borane preparation process, belong to gas separation technical field.The method includes: after ZIF-8 powder is vacuum dried, with 3-aminopropyl triethoxysilane in anhydrous toluene at 80 ℃ reflux reaction 12-24 hours, after washing, dry and obtain amido functionalization NH2-ZIF-8 composite adsorbent;It is filled in vertical fixed bed adsorption tower, and under-30 ℃-20 ℃, 0.3-0.8MPa, the crude ethyl borane gas containing boron trifluoride is imported and is adsorbed at low temperature;After adsorption saturation, regenerate by 80 ℃ heating and vacuum extraction.The grafting amount of amido on the surface of NH2-ZIF-8 obtained by the method is 2.0-3.5mmol / g, specific high selectivity adsorption of BF3 is realized, sufficient adsorption sites are provided, and the adsorbent has strong regeneration performance.

To provide a method for obtaining an optically active hydrogen-phosphine borane compound at high optical purity. Also, to provide a method for obtaining an optically active 2,3-bis(dialkylphosphino)pyrazine derivative at high optical purity. Provided is a method for producing an optically active hydrogen-phosphine borane compound comprising carrying out a decomposition reaction of an optically active phosphine borane compound in the presence of a phase-transfer catalyst using an alkaline aqueous solution and an organic solvent. Also provided is a method for producing an optically active 2,3-bis(dialkylphosphino)pyrazine derivative using the optically active hydrogen-phosphine borane compound obtained.

The application provides a wear-resistant and sweat-resistant acrylic paint, a preparation method and application thereof, and belongs to the technical field of paints.The wear-resistant and sweat-resistant acrylic paint disclosed by the application is composed of the following raw materials in parts by weight: 30-50 parts of water-based acrylic resin, 15-20 parts of cashew phenol-based polyurethane resin, 0.8-1.5 parts of adhesion promoter, 3-5 parts of titanate coupling agent, 3-15 parts of filler, 0.5-1.8 parts of thickening agent, 0.5-2.0 parts of leveling agent, 0.5-1.0 parts of wetting agent, 0.5-1.5 parts of defoaming agent, 0.5-2 parts of cosolvent and 5-15 parts of water; wherein the components of the water-based acrylic resin include acrylic monomer, dithio glycolic acid, tri-n-butyl borane and aziridine crosslinking agent; and a preparation method of the acrylic paint is also provided.The acrylic paint provided by the application has excellent mechanical properties, good adhesion, excellent water resistance, scratch resistance, wear resistance, chemical resistance, sweat resistance and corrosion resistance and the like, and can be applied to 3C products and the glasses industry, thereby prolonging the service life of the products.

The invention discloses a process for recovering rare earth oxide from rare earth oxide waste residue, and relates to the technical field of rare earth oxide recovery, and the process specifically comprises the following recovery steps: step 1, smelting: under the protection of argon atmosphere, melting neodymium iron boron alloy in a graphite crucible by adopting a vacuum induction melting furnace to obtain alloy mother liquor, and then carrying out heat preservation for 20-30 minutes; according to the technology for recycling the rare earth oxide from the rare earth oxide waste residues, rare earth oxidation loss is avoided through argon protection smelting, fluoride or borate is added into a graphite crucible, the smelting temperature is reduced by means of the low-melting-point characteristic of fluoride or borate, and meanwhile the adhesion loss of the rare earth oxide on the crucible wall is reduced by forming a rare earth-fluorine / boron composite melt; b-H bond breakage is accelerated through a platinum catalyst, borane by-products are recycled synchronously, rare earth colloid wrapping is avoided through EDTA disodium modified precipitation, and the COD value of wastewater is reduced; through the synergistic effect of gradient magnetic separation and pH regulation, the iron removal rate is larger than 99.9%, and the purity of the rare earth hydroxide reaches 99.8% or above.

The invention discloses a boron modified azo compound, a preparation method and application, and relates to the technical field of azo compounds, the preparation method comprises the following steps: step 1, mixing: adding an azo compound and organic boric acid, inorganic boric acid or borane into a solvent according to a mass ratio of 4: (08-1.2), and mixing to obtain a mixture; step 2, reaction: heating the mixture to 75-85 DEG C, and stirring for reaction to obtain a reactant; and 3, discharging: sequentially carrying out extraction, rotary evaporation and crystallization on reactants, and drying to obtain the boron modified azo compound. The preparation method has the effects of improving the thermal stability of the boron modified azo compound, reducing harmful byproducts and improving the mechanical property and chemical inertness; according to the preparation method of the boron modified azo compound, the boron material with high thermal stability is fully utilized, the azo compound is modified by the boron compound, so that the effect of a decomposition mechanism of the azo compound is changed, the operation is simple and safe, and the preparation method is suitable for large-scale mass production.

The invention discloses a preparation method of a sodium lauryl glycol carboxylate compound, which comprises the following specific steps: adding 1, 2-epoxydodecane and glycolic acid into a first reaction flask containing a solvent, and carrying out heating reaction under the action of a large-steric-hindrance catalyst to obtain lauryl glycol acetic acid; wherein the solvent is cyclohexane, normal hexane or methylbenzene, and the large steric hindrance catalyst is tri (pentafluorophenyl) borane; and S3, adding the lauryl glycol acetic acid prepared in the step S1 into a second reaction flask containing water, and adjusting the pH value of the solution in the second reaction flask to 8.5-11.5 by using a certain amount of sodium hydroxide solution to prepare lauryl glycol sodium carboxylate, namely the target compound. According to the preparation method disclosed by the invention, the single selectivity of the synthesis process is improved, so that the purity and yield of the sodium lauryl glycol carboxylate compound synthesized by the route are greatly improved, and the product becomes better and better in application.

The invention discloses a hexagonal scandium hydrogen compound and a preparation method thereof, and the preparation method comprises the following steps: taking a borane ammine complex as a solid hydrogen source, tabletting the borane ammine complex and elemental scandium through a mold, and stacking according to'hydrogen source-scandium-hydrogen source '; loading the assembly into a CVD diamond single crystal tube with holes, and carrying out secondary wrapping with NaCl to form a sealed reaction unit; carrying out segmented pressurization / depressurization in a cubic press, electrifying and segmented heating under the condition of 800-1200 DEG C, and carrying out pressure maintaining and cooling to complete synthesis; according to the method, local high hydrogen partial pressure is established under the action of moderate high pressure and double-layer sealing, external introduction of high-pressure hydrogen is avoided, and the equipment complexity and the safety risk are reduced; the product prepared by the invention is hexagonal-phase ScH3, can stably exist at normal temperature and normal pressure, and is different from cubic-phase ScH3 which can only be synthesized under an extreme high-pressure condition and cannot be kept stable after pressure relief, XRD and structure refinement are consistent with the standard, and the process can be repeated and amplified.

The invention relates to a synthesis method of chiral N-Fmoc-2-methyl azetidine-2-carboxylic acid, and relates to the technical field of organic synthesis.The synthesis method comprises the following steps that Fmoc-alpha-methyl-L-glutamic acid-5-tert-butyl ester is subjected to deprotection, and a compound I is obtained; carrying out esterification reaction on the compound I and aryl halide in an alkaline solution to obtain a compound II; removing an Fmoc protecting group from the compound II in an alkaline solution to obtain a compound III; the compound III is subjected to lactamization under the action of trimethylchlorosilane and tert-butyl magnesium bromide, and a compound IV is obtained; selectively reducing amide of the compound IV under the action of a borane reducing reagent to obtain a compound V; hydrolyzing the compound V in an alkaline solution, and removing benzyl to obtain a compound VI; and protecting the amino group of the compound VI through Fmoc to obtain a compound VII, namely the chiral N-Fmoc-2-methyl azetidine-2-carboxylic acid. The method has the effect of improving the synthesis efficiency of the chiral N-Fmoc-2-methyl azetidine-2-carboxylic acid, and the product has high yield and purity.

The invention discloses a method for preparing benzyl borate compounds through chromium catalysis, and belongs to the technical field of organic synthesis. According to the method, aryl carboxylic ester is taken as a raw material, pinacolborane is taken as a boron source and a hydrogen source, metal chromium salt is taken as a catalyst, a specific ligand and elemental magnesium are added, and reaction is performed in a tetrahydrofuran solvent, so that the deoxidation boronization reaction of the aryl carboxylic ester is realized. Benzyl monoborate or benzyl subunit diborate can be selectively prepared through ligand regulation and control. The method has the advantages of mild reaction conditions, cheap catalyst, wide raw material source, simple operation and good chemical selectivity.

A method of forming high quality a-BN layers. The method includes use of a precursor chemistry that is particularly suited for use in a cyclical deposition process such as in chemical vapor deposition (CVD), atomic layer deposition (ALD), and the like. In brief, new methods are described of forming boron nitride (BN) layers from precursors capable of growing amorphous BN (a-BN) films by CVD, ALD, or the like. In some cases, the precursor is or includes a borane adduct of hydrazine or a hydrazine derivative.

The invention discloses simple synthesis and antibacterial application of amino alcohol spiro indoline. The invention provides a skeleton structure of amino alcohol spiro indoline. The invention provides a synthesis method of the amino alcohol spiro-indoline compound, which comprises the following steps: uniformly mixing indole and o-aminobenzoic acid ester in a solvent, reacting at 80 DEG C under an acidic condition, and preparing the amino alcohol spiro-indoline compound without separation and borane reduction after an intermediate is obtained. The invention also provides an application of the amino alcohol spiroindoline skeleton in the aspect of bacteriostasis, and the amino alcohol spiroindoline skeleton is used for preparing a bactericide. The invention provides a method for efficiently synthesizing amino alcohol spiro indoline through two-step continuous reaction.

This invention relates to a near-infrared low-potential electrochemiluminescence dual-ligand stabilized gold nanoclusters, their preparation method, and applications. The method uses chloroauric acid as the gold source and thiomalic acid and sodium citrate as reducing and stabilizing agents, respectively, in a two-step synthesis. First, Au is reduced online using thiomalic acid. 3+ Water-soluble gold nanoclusters were prepared using a novel method. These nanoclusters were then incubated with sodium citrate, and based on the ligand exchange principle, gold nanoclusters co-coated with thiomalic acid and sodium citrate were synthesized. The raw materials required for this invention are readily available and all possess good water solubility. The synthesis apparatus is simple, the conditions are mild, and the operation is safe. The resulting dual-ligand-coated gold nanoclusters exhibit good stability and produce low-potential near-infrared electrochemiluminescence in the long-wavelength region in an aqueous system. This overcomes the limitation of most current electrochemiluminescent materials requiring hydrazine hydrate or carbazide as a co-reactant. Using a non-toxic tert-butylamine-borane co-reactant, low-potential electrochemiluminescence radiation of 0.57V in the near-infrared region was generated.

The invention relates to the technical field of compound synthesis, in particular to a method for directly reducing carboxylic acid into aldehyde. The preparation method comprises the following steps: mixing triphenylphosphine, dichloromethane, carboxylic acid and N-chlorosuccinimide, and reacting to obtain a reactant; mixing with pinacol borane and 4-dimethyl pyridine, and continuously reacting to obtain a continuous reactant; and separating and purifying to obtain aldehyde. The synthesis of the substrate carboxylic acid provided by the invention and the rapid deoxidation of the carboxylic acid are carried out to obtain an aldehyde product, especially the following compounds 2aa, 2ab, 2ae, 2bc, 2be, 2bf, 2bg, 2bh, 2bi, 2bj, 2bk and 2bl have catalytic hydrolysis effects on hypophosphamide; the compound 2bl has a particularly excellent effect on hydrolysis of hypophosphamide.

The invention discloses an adhesive and a preparation method thereof, the adhesive is used for bonding perfluoroether rubber and metal, and the adhesive is prepared from the following raw materials in parts by weight based on 100 parts of the adhesive: 80-98 parts of absolute ethyl alcohol; 0.2 to 5 parts by weight of a borane ammonia complex; 1 to 10 parts by weight of vinyl silane; and 1-5 parts by weight of silica sol. The adhesive provided by the invention is a combination of a borane ammonia complex, vinyl silane, nano silicon dioxide sol and absolute ethyl alcohol in specific parts; by selecting the combination of the borane ammonia complex, the silane coupling agent KH570 and the nano silicon dioxide sol to replace the existing common perfluoroether rubber / metal adhesive, the perfluoroether rubber / metal adhesive has excellent peel strength and high temperature resistance, and can be used for manufacturing door plates and racket products of semiconductor equipment.

The invention discloses a preparation method of a high-temperature-resistant antibacterial polyethylene composite plastic, which comprises the following steps: S1, by taking alkyl imidazole and M-dicarbon closed dodecaborane-1, 7-dicarboxylic acid as double ligands, carrying out thermal self-assembly on the double ligands and a metal salt solvent to obtain MOF (Metal Organic Framework); s2, dispersing the TiO2 / double-ligand MOF in an ammonium fluotitanate solution, adding a surfactant and inorganic weak acid, and performing in-situ deposition on TiO2 nanoparticles to prepare a TiO2 / double-ligand MOF compound; s3, carrying out melt extrusion granulation on the antibacterial master batch, polyethylene resin and an auxiliary agent to form antibacterial master batch; and S4, enriching the master batch on the surface layer by adopting a multi-layer co-extrusion process, keeping pure PE on the core layer, and cooling to obtain a finished product. According to the preparation method disclosed by the invention, the polyethylene composite material is endowed with excellent heat resistance and antibacterial durability, and the material has good anti-ultraviolet, self-cleaning, flame-retardant and smoke-suppressing properties, and is suitable for the fields with strict requirements on high-performance environment-friendly antibacterial plastics, such as food packaging, medical equipment, household appliance shells and the like.

The application provides a method for preparing nanometer noble metal by directly introducing reducing agent borane cluster into a carbon carrier, and the method is characterized in that: a borane cluster weak reducing agent is loaded on a carbon carrier to reduce and prepare a supported nanometer noble metal in situ, and the weak reducing property of the borane cluster can avoid the agglomeration of metal sites; the reducing agent is introduced into the carbon carrier, and the hard supporting effect of the carbon carrier can also avoid the large-scale agglomeration of the formed metal. The nanometer gold noble metal is dispersed in the carbon carrier, the dispersion of the nanometer noble metal is good, and the size of the nanometer noble metal is less than 10 nanometers. Compared with the prior art, the reducing agent borane cluster is directly introduced into the surface of the carbon carrier in the application, the in-situ reduction of noble metal ions is realized, and the supported nanometer noble metal with high dispersion and small particle size is effectively obtained. The method is simple in operation, reliable in preparation process and good in repeatability, and is beneficial to large-scale preparation.

The present invention relates to a stable equivalent body of 2, 2 ''-bis (1-phosphinoethyl)-1, 1''-diferrocene, which is useful as a ligand in various catalytic reactions including aromatic asymmetric hydrogenation, but is difficult to synthesize and / or separate and purify, and a method for efficiently producing the same, and more particularly, to a stable equivalent body of 2, 2 ''-bis (1-phosphinoethyl)-1, 1''-diferrocene, which is useful as a ligand in various catalytic reactions including aromatic asymmetric hydrogenation. The present invention provides: a diphosphine-diborane complex represented by general formula (1) (BH3) 2); and a method for producing the diphosphine-diborane complex, the method comprising reacting a magnesium source and an oxidizing agent with a phosphine-borane complex in this order.

The invention relates to the technical field of organic synthesis, and particularly discloses a synthesis method of 4, 4 '-methylene bis (N-cyclohexylcyclohexane-1-amine). The method comprises the following steps: mixing cyclohexanone and 2-methylpyridine borane, and heating to a reaction temperature; the preparation method comprises the following steps: reacting 4, 4 '-diaminodicyclohexylmethane with heat preservation, after the reaction is finished, cooling to room temperature, mixing a reaction solution with diluted hydrochloric acid, adding an organic solvent for extraction, collecting a water phase, then adjusting the pH value of the water phase to 8-9, adding an organic solvent for extraction, collecting an organic phase, drying and concentrating to obtain the 4, 4'-methylene bis (N-cyclohexylcyclohexane-1-amine). The synthesis method provided by the invention has the advantages of simple process, no need of high temperature and high pressure, mild and controllable reaction conditions, no influence of water in a reaction system, high conversion rate and good selectivity, conforms to the concept of green and safe production, and has a good development prospect.