424 results about "Hydroboration" patented technology

This invention relates to novel forms of clarified hydrocolloids including gels, films, foams, capsules and sponges. The invention also pertains to novel processes for producing the various physical forms of the clarified hydrocolloids. The invention also includes clarified hydrocolloid composites; borated cis 1,2-diol containing hydrocolloids; and clarified hydrocolloids of low viscosity.

The invention discloses a preparation method for propellant fuel. The preparation method comprises the following steps: uniformly mixing hydrazine or a methyl derivative thereof with a tetrahydrofuransolution of borane to perform a reaction, and after the reaction, performing rotary evaporation on the tetrahydrofuran solution to obtain a first product; adding a first solvent into the first product, then performing washing, and then performing rotary evaporation to remove the first solvent, so as to obtain a hydrazinoborane derivative. According to the method, hydroboration is carried out on ahighly-volatile hydrazine fuel and a methylated derivative of hydrazine, the obtained borohydride of the hydrazine is a colorless non-volatile liquid or a white solid, has no volatility and greatly reduces hazard of the hydrazine fuel, and is a novel aerospace propellant fuel since the ignition delay time of the hydrazine borofluoride is extremely short.

Processes for synthesizing borohydride compounds with reduced energy requirements and high efficiency are disclosed. The processes include the reaction of a base with a borane complex or diborane to produce a borohydride compound of formula YBH4, where Y is a monovalent cationic moiety.

The invention relates to a preparation method of a nanometer Pd or the Pd platinum gold electrocatalysis catalyzer which is used in a kind of fuel cell, whose characteristic lies in that dissolve the mixture of the ration Pd salt or the Pd salt and the platinum salt (in which the Pd atomic ratio accounts for metal quantity 10-100%) in the water, after joining the right amount complexing agent solution, elevates temperature to 0-80deg.C and keeps the temperature 5 minutes to 8 hours, then cooling to the room temperature, adjusts the pH value to 5 to 12 and adds the carbon carrier, then adds the solution of hydroboration sodium, hydrazine or formic acid and so on reducing agent under the 0 to 80deg.C , and maintains 10 minutes to 10 hours, then filtrating, laundering, dry, finally in inert atmosphere or reducing atmosphere through 100 to 300deg.C heat treatment in 0.5 to 10h, namely carries the carbon Pd or the Pd platinum electrocatalysis. The particle size of catalyst is controllable, adjustable, the composition is controllable, regards the heat treatment temperature to be different, the particle size which obtains is relatively 1.8nm to 20nm above, and the granule distribution is narrow, is suitable to serve as the direct formic acid fuel cell anode catalyst as well as the direct methanol fuel cell anti-methyl alcohol negative pole catalyst.

A process of forming a d-tocotrienol from a (2S)-vinylchromane compound, through hydroboration of the (2S)-vinylchromane to provide an organoborane, followed by coupling the organoborane with a halogenated C-14 sidechain compound under conditions of palladium-catalyzed cross-coupling is taught. Methods for providing the (2S)-vinylchromane compound and the halogenated C-14 compound are disclosed.

The invention relates to a carbon loaded noble metal catalyst, which is characterized in that the catalyst consists of a carrier and palladium and ruthenium which are loaded on the carrier, wherein the carrier is powdery fruit shell active carbon and is between 85 and 99.7 percent by weight; the palladium is between 0.2 and 10 percent by weight; and the ruthenium is between 0.1 and 10 percent by weight. The catalyst is obtained by performing acid treatment, ash removal and oxidation treatment on the carrier, namely the active carbon for removing surface reduction functional groups first, using a solution of the palladium and the ruthenium to perform soakage treatment, and using one or more among hydrogen, potassium borohydride or hydrazine hydrate to perform reduction treatment. The catalyst has high activity and selectivity and good stability in hydrogenation reaction of organic compounds containing carbonyl.

The present invention relates to processes for producing borohydride compounds. In particular, the present invention provides efficient processes and compositions for the large-scale production of borohydride compounds of the formula YBH.sub.4 by the reaction of a boron-containing compound represented by the formula BX.sub.3 with hydrogen or an aldehyde to obtain diborane and HX, and reacting the diborane with a Y-containing base selected from those represented by the formula Y.sub.2O, YOH and Y.sub.2CO.sub.3 to obtain YBH.sub.4 and YBO.sub.2. Y is selected from the group consisting of the alkali metals, pseudo-alkali metals, alkaline earth metals, an ammonium ion, and quaternary amines of the formula NR.sub.4.sup.+, wherein each R is independently selected from hydrogen and a straight- or branched-chain C.sub.1-4 alkyl group, and X is selected from the group consisting of halide ions, --OH, --R' and --OR' groups, chalcogens, and chalcogenides, wherein R' is a straight- or branched-chain C.sub.1-4 alkyl group.

Disclosed are novel phosphine-phosphoramidite compounds which may be employed in combination with a catalytically-active metal to effect a wide variety of reactions such as asymmetric hydrogenations, asymmetric reductions, asymmetric hydroborations, asymmetric olefin isomerizations, asymmetric hydrosilations, asymmetric allylations, asymmetric conjugate additions, and asymmetric organometallic additions. Also disclosed are a process for the preparation of the phosphine-phosphoramidite compounds, metal complex compounds comprising at least one of the phosphine-phosphoramidite compounds and a catalytically-active metal and hydrogenation processes utilizing the metal complex compounds.

A method for generation of hydrogen by combining a solid composition containing a borohydride compound and a base with an aqueous solution of an acid.

The present invention discloses a preparation method for optical activity active 3-amino butanol and optical activity 3-amino butyric acid. The optical activity active 3-amino butanol preparation method comprises: in a solvent, under effects of a hydroboration reduction agent and a Lewis acid, carrying out a reduction reaction on a compound represented by a formlu 65 to produce a compound represented by a formlu 14. The optical activity active 3-amino butyric acid preparation method comprises: carrying out a hydrolysis reaction on a compound represented by a formlu 64 to produce a compound represented by a formlu 65. According to the present invention, the preparation method has characteristics of cheap and easily-available raw materials, simple operation, short process route, no hazard of raw materials, high yield, little waste production, environment protection, high raw material conversion rate, high product chemical purity and high product optical purity, and the industrialization is easily achieved. The formulas 64, 65 and 14 are defined in the instruction.

The rate of hydrogen generation in proton-exchange-membrane (PEM) fuel cells is greatly accelerated by mixing a first aqueous alkali borohydride solution with a second aqueous solution in the presence of one or more transition metal catalysts: wherein the first solution comprises (a) 5 to 50 wt % MBH4, where M is an alkali metal, (b) 5 to 40 wt % alkali hydroxide or alkaline metal hydroxide, and (c) the balance water, and wherein the second solution comprises (a) 51 to 100% water, and (b) the balance, if any, comprising at least one water-soluble additive.

Disclosed are preparing processes for industrialized application of Corosolic acid with blood sugar lowering, weight reducing, anti-tumor and anti-inflammatory actions and maslinic acid with anti-tumor, anti-virus and cardiovascular diseases resistant actions. The processes include respectively preparing Corosolic acid and maslinic acid using 3-carbonyl ursolic acid ester and 3-carbonyl oleanolic acid ester by acid catalysed enolization esterification reaction, hydroboration oxidation reaction, catalytic hydrogenolysis reaction and haloidlysis reaction.

The invention discloses a synthetic compound comprising iminopyridyl oxazoline, a preparation method thereof, a metal complex of the compound and application of a prochiral organic compound which contains at least one carbon / carbon or carbon / heteroatomic double bond in hydroboration. According to the compound, the total yield of two steps of a high-efficiency synthetic route can reach 50%, and the metal complex is an excellent catalyst or a catalyst precursor which is used for asymmetric synthesis (such as asymmetric hydrogenation of prochiral, unsaturated and organic compounds). The invention also provides application of the metal complex as a homogeneous catalyst. The catalyst is used for preparing a chiral organic compound by being subjected to the hydroboration and hydrosilation asymmetric addition on the carbon or carbon heteroatomic double bond of the prochiral organic compound, and an ee value can be more than 90%.

The invention discloses application of tri-silicon amine rare earth complex to the catalyzing of hydroboration reaction of ketone and borane. The ketone is 2-acetylfuran, 2-acetylthiophene, 2-acetonaphthone or (substituted) phenyl ketone. The application has the advantages that the tri-silicon amine rare earth complex can catalyze the hydroboration reaction of the ketone and the borane under a mild condition (room temperature) in a high activity manner, and the use amount of catalyst is only 0.1-0.5% of the molar weight of the ketone; fast reaction is achieved, yield of above 90% can be reached after the reaction the performed for 10 minutes, catalyst use amount is lowered while yield is increased as compared with an existing catalyzing system, reaction time is short, the reaction condition is mild, and the economic atom synthesizing requirements are well satisfied.

Processes for synthesizing borohydride compounds with reduced energy requirements and high efficiency are disclosed. The processes include the reaction of a base with a borane complex or diborane to produce a borohydride compound of formula YBH4, where Y is a monovalent cationic moiety.

Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include phospholanes, P,N ligands, N,N ligands, biphenols, and chelating phosphines. The ferrocene-based irridium (R,R)-f-binaphane complex reduces imines to the corresponding amines with 95-99.6% enantioselectivity and reduces beta-substituted-alpha-arylenamides with 95% enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation of imines, asymmetric hydride transfer reactions, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, allylic alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions.

The invention discloses application of a beta-diimide bivalent rare earth boron hydrogen complex in catalysis of hydroboration reaction of ketone and boron hydride. Beta-diimide rare earth dichloride and NaBH4 react in a tetrahydrofuran solvent, and in-situ Na / K reduction is carried out, so that the beta-diimide bivalent rare earth boron hydrogen complex, namely [2,6-ipr2-(C6H3)-NC(Me)CHC(Me)N-(C6H3)-2,6-ipr2]Ln-BH4.2THF, is obtained. The beta-diimide bivalent rare earth boron hydrogen complex disclosed by the invention can catalyze the hydroboration reaction of ketone and boron hydride with high activity under mild conditions and has the advantages of short reaction time and mild reaction conditions, and an aftertreatment method is simple and convenient.

The invention discloses a Pb(Ni1 / 3Nb2 / 3)O3 (PNN) ligand-iron complex catalyst and a preparation method and application thereof. The catalyst is a compound with a general formula shown in the specification. In the general formula, R refers to an alkane group of C1-C30 or an alkane of C6-C30, and X refers to a halogen atom. The catalyst is prepared by performing a complexing reaction between a PNN ligand and FeX2. The PNN ligand-iron complex catalyst disclosed by the invention is good in catalytic activity on a hydroboration reaction of monoolefine and not only is high in selectivity and high in yield but also is mild in reaction condition. Moreover, the preparation method for the PNN ligand-iron complex catalyst is simple, is friendly to the environment, mild in reaction condition, higher in yield, simple in postprocessing and is easy for mass production, and raw materials are low in cost and can be easily got.

The invention relates to a ritodrine hydrochloride preparation method which comprises the following steps: using 4-methoxyphenylacetone as a raw material to react with liquid bromine so as to finish alpha-site bromization; then, reacting with methoxyphenylethylamine; and carrying out hydroxylation and hydroboration, and reducing to obtain the ritodrine hydrochloride product. By combining bromization, reaction with para-methoxyphenylethylamine and hydroxylation together, the invention realizes that intermediate steps do not need to be subjected to post treatment, thereby shortening processing steps to be adapted to industrial production. The ritodrine hydrochloride preparation method has the advantages of short period and low cost, and is convenient to operate, thereby greatly improving the production efficiency and yield.

The invention discloses an application of n-butylllithium in catalytic hydroboration of ketone and borane. The n-butyllithium is a commercial n-butyl lithium reagent, and the method includes: adding borane to a reaction flask subjected to dehydration and deoxygenation treatment without oxygen and water at inert gas atmosphere; adding a catalyst n-butyllithium with even mixing prior to adding ketone for hydroboration. The catalyst has good universality to aromatic ketones with different substitution positions and different electron effects as well as heterocyclic ketone and aliphatic ketone, and more choices for borate compounds with different substituent structures are provided.

Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include (R,S,S,R)-DIOP*. The ruthenium complex reduces enamide to the corresponding amine with up to 99% enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation, hydride transfer, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, hydrocarboxylation, isomerization, allylic alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions.

The invention relates to application of anilino lithium, in particular to a method of preparing borate ester based on hydroboration reaction of aldehyde and borane. The method comprises the followingsteps of under the conditions without water and oxygen, in an inert gas atmosphere, adding the borane in a reaction bottle subjected to dehydration and deoxygenation treatment, then adding the anilinolithium as a catalyst, performing uniform mixing, then adding the aldehyde for hydroboration reaction, and performing exposure in the air for reaction termination to obtain the borate ester as a product, wherein the aldehyde is selected from fatty aldehydes. By adopting the method provided by the invention, the condition that the anilino lithium can extremely efficiently catalyze cyclohexanecarboxaldehyde, propionaldehyde and heptanal to generate hydroboration reaction with the borane is discovered for the first time, and a new scheme is provided to prepare the borate ester by adopting a carbonyl compound and the borane to generate the hydroboration reaction.

The invention relates to application of p-methylanilinyl lithium to catalysis of aldehyde and borane to generate hydroboration reaction. The application comprises the following processes: under the water-free and oxygen-free environment and in the inert gas atmosphere, adding borane to a reaction flask subjected to dehydration and deoxidization treatment, then adding p-methylanilinyl lithium as acatalyst, performing uniform mixing, then adding aldehyde to perform hydroboration reaction, and exposing to the air to stop the reaction so as to obtain a product borate, wherein aldehyde is selectedfrom aromatic aldehyde or heterocyclic aldehyde. The catalytic activity in catalysis of aldehyde and borane to generate hydroboration reaction by p-methylanilinyl lithium is high (the dosage of the catalyst is only 0.1%), the reaction conditions are mild (room temperature), the reaction time is short (10 min), the reaction yield is high, the reaction is simple and controllable, the after-treatment is simple, and the reaction adopts a solvent-free system so as to reduce the pollution to the environment.

The invention discloses application of o-methyl-anilino lithium in the catalysis of aldehyde and borane hydroboration. Borane is added into a reaction bottle that is dewatered and deoxidized in an inert gas atmosphere in an anhydrous oxygen-free environment; the catalyst, o-methyl-anilino lithium, is added; mixing is performed well before an aldehyde is added; hydroboration is carried out; the reaction is ended after exposure to air so as to obtain borates; the aldehyde is selected from aromatic aldehydes and heterocyclic aldehydes. The catalyst disclosed herein is well applicable to aromaticaldehydes and heterocyclic aldehydes having different substitution positions and electronic effects; more choices are provided to attain borates with different substituent structures.

The invention relates to a preparation method for liquid polyborosilazane and belongs to the field of inorganic nonmetallic materials. The preparation method comprises the following steps: liquid polyborosilazane and 9-borabicyclo [3,3,1]-nonane are added in a solvent in inert atmosphere to obtain mixed solution, then the obtained mixed solution is hydroborated under the stirring condition, and then the solvent is removed after completion of hydroboration to obtain the liquid polyborosilazane. The preparation method solves the problems in the traditional polymer route that excessive cross-linking is easily caused in the hydroboration addition reaction, and solid polyborosilazane has poorer fluidity. The prepared liquid polyborosilazane has good fluidity and high ceramic yield and can be directly used for the high polymer infiltration and pyrolysis method for preparing SiBCN ceramic matrix composites.

The invention discloses a beta-diimide monovalent magnesium compound, a preparation method thereof and an application of the beta-diimide monovalent magnesium compound in hydroboration of aldehyde orketone. The preparation method comprises the following steps: under anhydrous and anaerobic conditions, a beta-diimine ligand reacts with a Grignard reagent, iodide of magnesium is generated and reduced by sodium, and a yellow crystal is obtained and is the beta-diimide monovalent magnesium compound. The beta-diimide monovalent magnesium compound is simple to synthesize, convenient to separate andpurify, clear in structure and high in yield; activity of the compound as a catalyst in catalysis of a reaction of aldehyde or ketone with pinacolborane is high, and the substrate universality is broad.

The invention discloses an NNN ligand, metal complexes thereof, preparation methods and application, and particularly provides an NNN ligand 1, a metal complex 2 of the NNN ligand, a metal complex 3 of the NNN ligand and preparation methods of the NNN ligand 1 and the metal complexes, as well as application of the metal complex 3 of the NNN ligand to catalysis on hydroboration reaction of bis-substituted olefin, especially application of the metal complex 3 to catalysis on asymmetric hydroboration reaction of 1, 1-bis-substituted olefin. The metal complex 3 of the NNN ligand has good catalytic activity in the hydroboration reaction of the bis-substituted olefin, especially asymmetric hydroboration reaction of the 1, 1-bis-substituted olefin, has excellent regioselectivity and enantioselectivity, and is high in yield and mild in reaction conditions; besides, the preparation methods of the NNN ligand and the metal complexes thereof are simple, environment-friendly, mild in reaction conditions, relatively high in yield, and simple in post-processing, and the raw materials are low in cost and easy to obtain, so that the preparation methods are suitable for industrial production. (The formulas of the NNN ligand 1, metal complex 2 and metal complex 3 are shown in the description).

The invention is concerned with a kind of method to produce amino acid-selenium methionine as animal nutrition additive. Take dimethyl diselenide as material and deoxidize it in alkalescence solution to get methyl hydroselenide negative ion with borohydride metal or metal of borohydride. Then react with 4-halogen-alpha-amino acid or its ramification to get selenium methionine through hydrolyzing and adjusting pH valve. The reaction system is carrying in water solution without inert gases and avoids the operation without water and oxygen. The material is common with good safety and it is easy for operation and higher productivity with appropriate condition and it do not need special equipment.