8 results about "Corosolic acid" patented technology

The invention discloses a formula of a composition capable of assisting in reducing blood sugar and preventing diabetes, and relates to the field of health food, the composition has the effects of reducing blood sugar and preventing diabetes, and the composition comprises the following composition components: 0.25 to 0.37% of bitter gourd peptide, 0.018 to 0.026% of corosolic acid, 0.39 to 0.48% of mulberry leaf extract, 0.083 to 0.095% of pseudo-ginseng extract, 0.115 to 0.132% of radix polygonati officinalis extract, and 0.00003 to 0.00005% of chromium-enriched yeast. By adopting the composition formula for assisting in reducing blood sugar and preventing diabetes, the formula composition has the effects of assisting in reducing the blood sugar level and treating. Meanwhile, the composition also has a synergistic effect on prevention of diabetes caused by hyperglycemia symptoms, the components of the composition are equal-part compositions formed by physical stirring and uniform mixing, and the increase of postprandial blood sugar level can be effectively inhibited, so that the effects of assisting beta cells of a body to secrete insulin and improving the blood sugar level are achieved. And insulin can promote the utilization of sugar by cells, the synthesis of hepatic glycogen and the improvement of the metabolism of sugar, so that the effect of reducing blood sugar is finally achieved. The raw materials of the composition can be purchased and obtained in the market, the raw materials are simple and easy to obtain, the production benefit is high, and the composition is suitable for being widely used.

The present invention discloses loquat triterpenic acid synthesis key enzyme genes EjCYP716A1 / 2 and EjCYP716C1 / 2 and applications. The present invention first reveals the function of a new oxidized squalene cyclase gene EjOSC2 in synthesizing α / β-amyrin in the process of triterpenic acid synthesis; clarifies the function of gene EjCYP716A1 / 2 in catalyzing oxidation reaction at C-28 of α / β-amyrin to convert it into ursolic acid and oleanolic acid; and clarifies the function of EjCYP716C1 / 2 in catalyzing hydroxylation reaction at C-2 of ursolic acid / oleanolic acid to convert it into corosolic acid / maslinic acid. These five genes can provide gene resources for regulating the accumulation level of ursane-type and oleanolic acid-type triterpenic acids in tissues such as leaves of medicinal plants loquat, and also lay the foundation for batch production of natural active triterpenic acid components such as loquat ursolic acid and corosolic acid through environmentally friendly production processes such as gene editing or fermentation engineering.

The object of the present invention is to provide a composition that exhibits an effect of increasing or inhibiting the decrease in muscle mass. [Solution] The present inventors have conducted extensive research to solve the above problems and have found that by designing the daily intake of corosolic acid to be 0.2 to 20 mg / day, an excellent effect of increasing or suppressing the decrease in muscle mass can be obtained, thus completing the present invention.

The invention discloses an application of corosolic acid in preparation of a medicine for preventing or treating a non-alcoholic fatty liver disease, and relates to the technical field of medicines. The research finds that corosolic acid improves the treatment mechanism of the non-alcoholic fatty liver disease from the perspective of dynamic balance of intestinal flora, and in addition, corosolic acid has the effects of reducing the in-vivo lipid level and protecting the liver at the same time; the corosolic acid is used for improving the non-alcoholic fatty liver disease by playing a role through the hepatic intestinal axis, balancing the relative expression abundance of intestinal flora and regulating a metabolic pathway, so that the intestinal injury is reduced, the effect of protecting the liver is played, and a foundation is laid for later development of medicines for treating the non-alcoholic fatty liver disease by corosolic acid.

A water-cooled crusher for extracting corosolic acid in lagerstroemia speciosa relates to the field of crushers, and comprises a crusher body and a feed port structure, a mounting plate is mounted on the right side of the pulverizer body through a discharging head assembly, an inserting piece is inserted into the exterior of the mounting plate, and the exterior of the inserting piece is connected with a blocking piece; the feeding port structure of a funnel-shaped structure is installed above the side edge of the pulverizer body, a control rod is installed in the feeding port structure through a transverse plate structure, a drawing structure is installed at the bottom end of the control rod through a bottom plate, and a rotating structure is fixed to the outer end of the drawing structure. The water-cooled pulverizer solves the problems that when raw materials are added into an existing water-cooled pulverizer, the raw material circulation effect is poor, blockage is prone to occurring, manual dredging is needed, however, potential safety hazards exist in manual dredging, and after pulverizing is completed, discharged materials are prone to splashing and can fall onto the ground, and waste is caused.

The invention relates to new application of corosolic acid, in particular to a medicine for resisting respiratory syncytial virus, the medicine comprises corosolic acid, the medicine further comprises at least one pharmaceutically acceptable carrier, and the carrier is selected from excipient, stabilizer, disintegrating agent or sustained-release material. The administration dosage of the corosolic acid is 16 mg / kg to 50 mg / kg. The pharmacological action of corosolic acid in resisting the respiratory syncytial virus is found for the first time by carrying out HE staining, ELISA, PCR and other related antiviral researches on corosolic acid, and the oral preparation prepared by the invention is simple in preparation method, remarkable in effect and high in pertinence, and has positive significance in treatment of resisting the respiratory syncytial virus.

To provide an oral composition exhibiting superior hair growth effect.SOLUTION: An oral composition for hair growth comprising corosolic acid and polyamine.SELECTED DRAWING: Figure 1

The invention relates to the technical field of food science and provides corosolic acid W / O type Pickering emulsion as well as a preparation method and application thereof. The W / O Pickering emulsion is prepared by adopting natural corosolic acid as a solid particle stabilizer, so that the solubility, the stability and the function availability of the corosolic acid can be improved, the corosolic acid is endowed with the potential of food application, and meanwhile, the use of a chemical emulsifier is avoided. Results of the embodiment show that the corosolic acid W / O type Pickering emulsion provided by the invention has good stability and good bioavailability, the bioaccessibility of corosolic acid is improved to 57.09%, and the inhibition effect on alpha-glucosidase is also obviously improved.