The invention discloses
lactobacillus rhamnosus capable of reducing
blood sugar and blood fat and application of the
lactobacillus rhamnosus. The
lactobacillus rhamnosus CU262 strain provided by the invention is preserved in the Guangdong Microbial Culture Collection Center on March 17, 2025, and the preservation number of the
lactobacillus rhamnosus CU262 strain is GDMCC (China General
Microbiological Culture Collection Center) No.66018. The
lactobacillus rhamnosus CU262 strain provided by the invention has been preserved in the Guangdong Microbial Culture Collection Center on March 17, 2025. Researches show that the CU262 strain has a remarkable inhibition capability on a key
enzyme alpha-
glucosidase causing blood glucose increase, and the inhibition rate reaches 98% or above; moreover,
cholesterol can be efficiently degraded at the same time, the degradation rate reaches 74% or above, and good acid-resistant and cholate-resistant capacity, self-aggregation capacity and
oxidation resistance are achieved. The CU262 strain is safe in source, free of side effects, low in price, easy to obtain and easy to prepare. The invention provides more sources and choices for preparing preparations for efficiently inhibiting alpha-
glucosidase and degrading
cholesterol and hypoglycemic and lipid-lowering products, and provides a new thought for
adjuvant therapy of diabetes and
obesity.