133 results about "Garcinia" patented technology

The invention describes a pharmaceutical composition and method for treating cancer comprised of A) 2,3-dimethoxy-5-methyl-1,4-benzoquinone and/or B) at least one of wild yam root, teasel root, balm of gilead bud, bakuchi seed, dichroa root, kochia seed, kanta kari, bushy knotweed rhizome, arjun, babul chall bark, opopanax and bhumy amalaki; optionally one or more of frankincense, garcinia fruit, vitex, dragons blood, mace, sage and red sandalwood with at least c) one compound capable of maximizing oxidative mitochondrial function preferably riboflavin or vitamin B₂ derivatives, FAD, FMN, 5-amino-6-(5′-phosphoribitylamino)uracil, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin, vitamin B₁, lipoic acid, biotin, vitamin B₆, vitamin B₁₂, folate, niacin, vitamin C and pantothenate and/or d) at least one lactic acid dehydrogenase inhibitor (preferably 2′,3,4′5,7-pentahydroxyflavone) and optionally f) an alkalizing agent (aloe vera, chlorella, wheat grass, sodium or potassium bicarbonate, potassium) g) an antiproliferative herb (speranskia or goldenseal) and h) a pharmaceutically acceptable carrier.

The invention describes a nutraceutical composition and method for preventing/treating cancer comprised of A) quinones (2,3-dimethoxy-5-methyl-1,4-benzoquinone, thymoquinone, tocopherolquinone) B) compounds capable of maximizing oxidative mitochondrial function preferably riboflavin, FAD, FMN, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin, vitamin B₁, lipoic acid, biotin, vitamin B₆, vitamin B₁₂, folate, B3, C and pantothenate C) lactic acid dehydrogenase inhibitors; 2′,3,4′5,7-pentahydroxyflavone, epigallocatechin gallate, quercetin, citric acid, rosemary, black walnut, clove, nutmeg, licorice root, coriander, cinnamon, ginger root, myrrh gum and green tea D) alkalizing agents: aloe vera, chlorella, wheat grass, apple cider vinegar, burdock root, kudzu root, alfalfa, barley grass, spirulina, parsley leaf, calcium, magnesium, potassium or bicarbonate salts E) potent tumoricidal herbs; gromwell root, wild yam, beth root, teasel root, balm of gilead bud, frankincense, bakuchi seed, dichroa root, kochia seed, kanta kari, sweet myrrh, galbanum, garcinia fruit, mace, white sage and tumoricial plant derived constituents: gambogic acid, shikonin, diosmin or boswellic acid F) an antiproliferative herb (speranskia or goldenseal) and G) a pharmaceutically acceptable carrier.

Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.

A method of making an alternative bottled water comprising as main ingredients, D-ribose, L-carnitine, Coenzyme Q10, Adenosine triphosphate, Taurine, Garcinia combgia, Chromium polynicotinate, or chromium picolate with or without L-Aspartic acid to provide cardiovascular fitness and overall physical energy. Said energy fitness water may also contain a non-nutritive or nutritive sweetener, aroma and coloring. The bottled water prepared from these ingredients has pH range from 3.5 to 7.0 dependent on processing and packaging of the bottled water.

Embodiments of the present disclosure related to compounds and compositions derived from G. buchananii baker and methods thereof.

In this patent we describe the purification of prenylated benzophenones from the fruit rinds of Garcinia species and its evaluation as an inhibitor for Histone acetyltransferases p300 and PCAF. We have found that prenylated benzophenones are potent HAT inhibitors of p300 (IC₅₀-1 μM) and pCAF (IC₅₀-15 μM). The inhibitors significantly repress the p300 HAT dependent transcriptional activation from in vitro assembled chromatin template but had no effect on transcription from DNA. These results suggest that the compounds could be specific to HATs. Thus these compounds should be useful as biological switching molecule for evaluating the role of p300 and PCAF in cellular functions and may be useful as new chemical entities for the development of anticancer drugs.

Formulas for producing compositions for the dietary supplement and nutraceutical products, containing virgin olive oil, vitamins, substances as vincamine, vinpocetine or vinburnine, as well as herbal extracts from Vinca Minor and Crioceras longiflorus. The present invention also relates to the oral administration of these compounds, to alleviate mental fatigue or poor cognitive function and anti-ageing prevention.

The invention relates to the field of medicinal chemistry, in particular to a garcinia derivative (I), a preparation method thereof and the application of the derivative in pharmacy. The derivative is a structural analogue of a garcinia natural product such as gambogic acid and has the molecular weight which is lower than that of the gambogic acid, and hetero atoms and hydrophilic groups are introduced or further salified, so that the absorbability of a gastrointestinal tract is improved; and the derivative has an antitumor effect and can be used for preparing antitumor medicaments.

The invention provides weight loss health food containing hyaluronic acid. The food is formed by wrapping a content with a hyalurate shell and comprises the following raw materials by weight: 5-20 parts of L-carnitine, 10-30 parts of garcinia camnogia extract, 5-30 parts of lotus leaf extract, 1-20 parts of tea polyphenol, 0.1-10 parts of vitamin, 1-30 parts of dietary fiber, 0.1-20 parts of dextrin, 0.1-20 parts of chondroitin sulfate, 0.1-20 parts of glucosamine salt, 0.1-20 parts of collagen, 0.1-20 parts of conjugated linoleic acid glyceride and 0.1-30 parts of hyaluronate. The hyaluronateis a combination of a high molecular hyaluronate and a low molecular hyaluronate in the mass ratio of 20:1-1:20. The high molecular hyaluronate has the molecular weight of 1000KDa-3000KDa, and the low molecular hyaluronate has the molecular weight of 1KDa-800KDa. The weight loss health food has the advantages of losing weight, protecting deployable joints and reducing cutis laxa.

Aromatase inhibitors (AIs) are disclosed which are useful in the treatment and prevention of post-menopausal breast cancer. New AIs derived from natural products are disclosed that are evaluated for clinical utility for treating post-menopausal breast cancer and may also act as chemopreventive agents for preventing breast cancer. Several pure compounds demonstrated AI activity using a noncellular, enzyme-based microsomal and a cell-based aromatase assay. Correlations are made between structural classes with levels of aromatase inhibition. The disclosure may be utilized to direct synthetic modification of natural product scaffolds to enhance aromatase inhibition or to standardize botanical dietary supplements for increased aromatase inhibition activity.

The invention relates to an antitumor medicament which is prepared from the following raw materials: (1) gamboges 0.5-1.5 weight parts, (2) flavescent sophora root 5-15 weight parts, or flavescent sophora root essence 0.1-0.3 weight part, sophocarpidine 0.1-0.3 weight part. The invention also discloses the process for preparing the medicament.

Herbal extracts composition suitable for weight management in mammals is disclosed. The composition comprises a mixture of Garcinia extract, Green tea extract, Green coffee extract and Banaba extract. The method of reducing weight, and treating diabetes in mammals involve oral administration of the composition. The invention further relates to a method of producing and standardizing the individual extract useful for human health.

The invention relates to the technical field of medicine preparation, is a traditional Chinese medicine for preventing and treating chemotherapeutic phlebitis, and solves the problems that the existing medicines for treating the chemotherapeutic phlebitis has a poor effect, high price and the like. A compounded garcinia and radix angelicae ointment for preventing and treating chemotherapeutic phlebitis comprises the following medical components in parts by mass: 500-1000 parts of garcinia, 150-250 parts of radix angelicae, 1000-1500 parts of fritillary, 200-300 parts of rheum officinale, 200-300 parts of camphor, 200-300 parts of borneol, 100-300 parts of costus root and 100-300 parts of mint. According to the invention, the garcinia as a monarch drug is taken as a medicine prescription for treating the chemotherapeutic phlebitis, the treating methods of clearing heat and expelling damp, detoxicating and removing pus, relieving swelling and pain, activating blood and removing blood stasis and dredging main and collateral channels are used to prevent and treat the chemotherapeutic phlebitis.

The invention aims at providing a method of efficiently extracting and separating gambogic acid and neogambogic acid from gamboge, serving as a traditional Chinese medicine. The method comprises the following steps: crushing the gamboge, carrying out microwave extraction, and concentrating to obtain an extract A; leaching with petroleum ether, dissolving and filtering with ethanol, and carrying out chromatographic separation by virtue of a simulated moving bed to obtain a component B rich in the gambogic acid and a component C containing the gambogic acid and the neogambogic acid; and recovering a solvent, drying to obtain products, including the gambogic acid with the purity to be above 95 percent and a mixture of 10-20 percent of the gambogic acid and 30-50 percent of the neogambogic acid, in two specifications. The method of extracting the effective components of the gamboge, serving as the traditional Chinese medicine, is simple in step and high in product purity and is capable of simultaneously obtaining the products, including the gambogic acid and the neogambogic acid, in two specifications, fully extracting and separating the effective components from the raw materials and improving the production efficiency while saving the raw material resources.

The invention discloses a kind of macrolide antibiotic and the manufacturing method, the method includes following steps: (1) culture yeasting: óƒ the producing of incubation media: blends glucose, soluble starch, peptone, corn pulp, K2HPO4, MgSO4.H2O, NaCl and water, carries on sterilization; ó yeasts: the garcinia grey chain mycete strain into the sterilized incubation media, shakes the bottle and carries on yeasting; (2) processes the yeasted liquid: óƒ centrifugates yeasted liquid; ó isochoric extract acetic ester, partial acetic ester is inversely extracted by water and the pigment impurities are eliminated; ó� reclaims acetic ester and gets brown oil which has active part; óœ carries on silica pole chromatography and gets the coarse product; ó¦ purifies the coarse product.

The invention discloses a micrococcus luteus strain and an application thereof. The micrococcus strain is morphologically characterized in that the appearance of the bacterial colony of the strain on an LB culture medium is golden yellow, in a concave and cone-frustum shape, opaque, even in edge, smooth and moist in surface, and shiny, and the size of the bacterial colony is approximately 2 millimeters. The strain is gram-positive tetracoccus. The micrococcus luteus strain is a strain which can efficiently decompose high-sulfur coal gangue and release phosphorus.

The invention discloses a medicament for treating periodontitis, which is prepared from the following main raw materials in parts by weight: 9-16 parts of rhizoma alismatis, 7-14 parts of acanthopanax, 10-15 parts of hairy holly leaf, 8-16 parts of commelina diffusa, 6-13 parts of Chinese pear-leaved crabapple, 9-14 parts of populus alba leaf, 8-13 parts of orchis, 6-12 parts of rose hip, 7-13 parts of oblongleaf garcinia seed oil, 9-12 parts of spinach beet, 10-16 parts of dodder, 7-15 parts of Chinese usnea, 3-6 parts of daphne giraldii, 10-14 parts of dandelion and 8-12 parts of sheareria nana. The medicament disclosed by the invention has the effects of clearing away heat and purging pathogenic fire, resisting bacteria and diminishing inflammation as well as eliminating swelling and healing sores, is capable of quickly reducing an inflammatory surface and alleviating pain, has a good effect on treating periodontitis, and is free of toxic or side effect.