4500 results about "Benzoic acid" patented technology

To provide a timber antiseptic agent which exhibits superior safety and superior antibacterial performance with low influence on the human body and environment.SOLUTION: The present invention relates to a timber antiseptic agent containing an alkyl 4-hydroxybenzoate represented by formula (1) [where R represents an alkyl group having 5 to 10 carbon atoms] or a salt thereof.SELECTED DRAWING: None

A compound of formula (I) or a pharmaceutically acceptable salt or hydrate thereof wherein X-Y is -NHSO2- or -SO2NH-; R1 is H, CN or alkyl; R2 is selected from COOH and a tetrazolyl group; R3 is selected from H, Cl and alkyl; R4 is selected from H and halo; R5 is selected from H, alkyl, haloalkyl, SO2-alkyl, Cl, alkoxy, OH, CN, hydroxyalkyl, alkylthio, heteroaryl, cycloalkyl, heterocycloalkyl and haloalkoxy; R6 is H; R7 is selected from H, CN, haloalkyl, halo, SO2-alkyl, optionally substituted heteroaryl, SO2NR14R15, CONR10R11 and alkyl; R8 is selected from H, alkyl, haloalkyl and halo; R9 is H or halo; and R10, R11, R12, R14, and R15 are H or alkyl; R13 is selected from alkyl, halo, alkoxy, CN, haloalkyl and OH; and m is 0-3. The compounds of formula (I) modulate ERAP1 (endoplasmic reticulum aminopeptidase 1) and are for use in treating proliferative, immune or inflammatory disorders, particularly cancer or leukemia. The compounds of formula (I) stimulate a neo-antigen directed immune response in the subject. A method for producing an antigen-presenting cell which presents a neo-antigen using compounds of formula (I) is disclosed. An immunogenic composition comprising an antigen-presenting cell is also disclosed. Exemplified compounds include 4-cyclopropyl-3-(N-(2-(morpholin-3-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid.

A construction method for and a use of rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule characteristic spectra. The construction method comprises the following steps: dissolving a test sample by using a solvent, and extracting to obtain a solution to tested; and measuring said solution by using high-performance liquid chromatography (HPLC) to obtain rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule characteristic spectra, wherein chromatographic conditions of the HPLC are as follows: the chromatographic column is a C18 column; and gradient elution is performed by using acetonitrile as mobile phase A and a 0.1% phosphoric acid aqueous solution as mobile phase B. HPLC is used, gradient elution is performed by using acetonitrile and a 0.1% phosphoric acid aqueous solution as mobile phases, and 4-hydroxybenzoic acid is used as a reference object, so that rhizoma pinellinae praeparata decoction piece, standard decoction and formula granule HPLC characteristic spectra are established; the method has good repeatability and precision, is stable and reliable, and can control the quality of rhizoma pinellinae praeparata decoction pieces, a standard decoction and formula granules.

Disclosed in the present invention are a PET release film base film having low surface roughness and a preparation method therefor. The release film base film comprises three layers which are stacked: a core layer and two surface layers located on both sides of the core layer. The release film base film is obtained via three-layer co-extrusion by means of taking an auxiliary extrusion resin as a raw material of the two surface layers and a primary extrusion resin as a raw material of the core layer; the auxiliary extrusion resin is obtained by mixing an anti-blocking agent PET masterbatch and a PET base material in a mass ratio of 1:5-1:15; and the primary extrusion resin is a pure PET base material. The release film base film of the present invention has low surface roughness, low haze and excellent overall performance. Since large-particle benzoic acid-modified nano aluminum oxide has the refractive index very close to that of PET base films, the present invention can effectively avoid adverse visual impacts caused by a difference in the refractive index at interfaces between nanoparticles having large particle diameters and resin matrixes, thus effectively reducing the haze.

The invention discloses a tetranuclear ladder type organic tin carboxylate complex as well as a preparation method and application thereof, and belongs to the technical field of metal complexes, the tetranuclear ladder type organic tin carboxylate complex is prepared by taking para-position or ortho-position substituted benzoic acid as a ligand and taking organic tin dimethyl tin oxide as a substrate. The preparation method is simple to operate and mild in condition. The tetranuclear ladder type organic tin carboxylate complex can be used as a photocatalyst for photocatalytic production of H2O2, and the photocatalytic H2O2 production rate is as high as 5.12 * 10 < 3 > [mu] mol.g <-1 >. H <-1 > and is higher than the H2O2 production rate of a photocatalyst reported in the existing literature.

The invention belongs to the field of agricultural biotechnology and environmental microbiological engineering, and discloses mesotrione nitroreductase Mstnr as well as a coding gene and application thereof. The nucleotide sequence of the gene is SEQ ID NO.1, the full length is 678bp, 225 amino acids are encoded, and the amino acid sequence of the gene is SEQ ID NO.2. The highest homology of the Mtnr and reported nitroreductase is only 49.2%, so that the Mtnr is a new nitroreductase gene. The nitroreductase Mtnr provided by the invention can catalyze nitro reduction of mesotrione and convert mesotrione into a product 2-amino-4-methylsulfonylbenzoic acid (AMBA) without herbicidal activity, which indicates that the Mtnr gene has a huge application prospect in biodegradation detoxification and repair of mesotrione.

The invention belongs to the field of agricultural biotechnology and environmental microbiological engineering, and discloses mesotrione nitroreductase Mtnr as well as a coding gene and application thereof. The nucleotide sequence of the gene is SEQ ID NO.1, the full length is 756bp, 251 amino acids are encoded, and the amino acid sequence is SEQ ID NO.2. The maximum homology of the Mstnr and reported nitroreductase is only 50.6%, so that the Mstnr is a new nitroreductase gene. The nitroreductase Mstnr provided by the invention can catalyze nitro reduction of mesotrione, and the mesotrione is converted into a product 2-amino-4-methylsulfonyl benzoic acid (AMBA) without herbicidal activity, so that the Mstnr gene has a huge application prospect in biodegradation detoxification and repair of the mesotrione.

The invention relates to the technical field of heat-conducting graphite materials, in particular to a POD precursor film, a POD-based graphite film and a preparation method of the POD precursor film, the POD-based graphite film and the preparation method of the POD precursor film. After the reaction is finished, obtaining an antioxidant modified aromatic polyoxadiazole polymer solution; the preparation method comprises the following steps: coating an antioxidant modified aromatic polyoxadiazole polymer solution with a wiped film, then carrying out solidification forming in a multi-stage coagulation bath, and finally neutralizing, washing and drying to obtain a POD precursor film; the coagulating bath is an aqueous solution of sulfuric acid and boron compounds and an aqueous solution of sulfuric acid. And carrying out carbonization treatment and graphitization treatment on the POD precursor film to obtain the POD-based graphite film. According to the preparation method, the boron element is cooperatively introduced into and out of the POD precursor film, so that the oxidation resistance of the graphite film is remarkably improved while the high thermal conductivity is maintained.

The invention relates to a preparation method of a catalyst for synthesizing 2, 6-dimethylphenol, which comprises the following steps: mixing ferric salt, aluminum salt, magnesium salt, an acidic material and water to obtain a solution A; mixing sodium silicate, a template agent and water to obtain a solution B; mixing the solution A and the solution B, aging, crystallizing, filtering, drying and calcining to obtain a catalyst precursor I; mixing with an alkaline solution, and filtering to obtain a catalyst precursor II; then mixing with an acidic solution, filtering to obtain a solid, and then washing and calcining to obtain a catalyst; the preparation method of the 2, 6-dimethylphenol comprises the following step of preparing the 2, 6-dimethylphenol by taking methanol, phenol, water and benzoic acid as raw materials in the presence of the catalyst. The catalyst provided by the invention has good catalytic activity, reduces the problem of carbon deposition, and has good selectivity and high phenol conversion rate when being used for preparing 2, 6-dimethylphenol.

The invention discloses a method for catalytically oxidizing lignin to depolymerize into an aviation oil intermediate by using a cellulose carbon aerogel supported copper nano-catalyst. Comprising the following steps: (1) dissolving cellulose powder into a mixed alkali solution of NaOH and urea, and stirring at low temperature to obtain a clear and transparent cellulose solution; and washing to be neutral to obtain well dispersed cellulose suspension. And (2) carrying out suction filtration molding, and freeze-drying for a period of time to obtain the cellulose aerogel. And (3) immersing in an ethanol solution of copper nitrate for ultrasonic treatment, and drying in a vacuum drying oven. And (4) carrying out high-temperature calcination in an N2 atmosphere to obtain a catalyst which is marked as Cu / CA. And (5) the catalyst can efficiently catalyze a Fenton-like reaction to oxidize a dimer model compound of lignin in acidic, neutral and alkaline environments to obtain products including benzoic acid, acetophenone, benzyl alcohol, phenol and the like, the required hydrogen peroxide concentration is low, and the catalyst has the advantages of simple process, high catalytic activity, low cost and the like, can be used for effectively degrading lignin to prepare aviation oil intermediates, and has wide application prospects. And repeated cyclic utilization is realized.

The invention discloses a Cupriavidus sp. HY21 strain of BHA (benzohydroxamic acid) is separated from soil in a mining area, the Cupriavidus sp. HY21 strain is preserved in Guangdong Microbial Culture Collection Center on September 11, 2024, the preservation number of the Cupriavidus sp. HY21 strain is GDMCC No: 65117, and the optimal degradation conditions of the Cupriavidus sp. HY21 strain are that the pH is 5.5, the temperature is 30.5 DEG C, and the inoculation amount is 1.0 (OD 600nm). Under the condition, the degradation rate of 100 mg / L of BHA can reach 97% or above within 24 h. In addition, the hydroxamic acid collecting agent, benzoic acid, salicylic acid, phenol and / or catechol can be well degraded, and the method can be used for pollution remediation of the flotation reagent BuX.

The invention belongs to the field of agricultural biotechnology and environmental microbiological engineering, and discloses a novel mesotrione nitroreductase Bamnr, and a coding gene and application thereof. The nucleotide sequence of the gene is SEQ ID NO.1, the full length is 639bp, 212 amino acids are encoded, and the amino acid sequence of the gene is SEQ ID NO.2. The highest homology of Bamnr and reported nitroreductase is only 69.4%, so that Bamnr is a new nitroreductase gene. The nitroreductase Bamnr provided by the invention can catalyze nitro reduction of mesotrione, and the mesotrione is converted into a product 2-amino-4-methylsulfonyl benzoic acid (AMBA) without herbicidal activity, so that the Bamnr gene has a huge application prospect in biodegradation detoxification and repair of the mesotrione.

The invention relates to the technical field of PET geothermal films, and discloses a high-temperature-resistant geothermal film and a preparation method thereof.The high-temperature-resistant geothermal film is obtained through blending extrusion and blow molding of polyethylene glycol terephthalate, carboxyl polyetherimide and modified graphene. The carboxyl polyetherimide contains a benzoate structural unit similar to PET, the carboxyl polyetherimide and the benzoate structural unit form an alloy-like system with good compatibility, the modified graphene is good in dispersity and excellent in compatibility with PET, meanwhile, the modified graphene contains more carboxyl groups, and the carboxyl groups and carboxyl groups of side chains of the carboxyl polyetherimide interact with each other to form hydrogen bonds and the like; the graphene can be uniformly dispersed in a composite system of PET and carboxyl polyetherimide, so that a better reinforcing effect is achieved, and the tensile strength and the elongation at break of the PET composite geothermal film are remarkably improved. After high-temperature thermal aging, the geothermal film is high in retention rate of tensile strength and elongation at break and good in high-temperature resistance.

Methods for preparing a salt of urolithin A and, in turn, urolithin A. Combining in an alkaline aqueous solution a copper-containing catalyst, 2-bromo-5-hydroxybenzoic acid, and resorcinol produces a salt of urolithin A. Urolithin A has been prepared by protonating a salt of the compound.

The invention belongs to the technical field of high polymer materials, and particularly relates to spinning-grade all-aryl polynaphthyl ester resin and a preparation method thereof. According to the invention, p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic acid, aromatic dicarboxylic acid and ethylene glycol monomer are adopted as raw materials, polymerization reaction is carried out under the action of the catalyst, spinning-grade all-aryl polynaphthyl ester resin is successfully obtained under specific reaction conditions, and the spinning-grade all-aryl polynaphthyl ester resin has high molecular weight, low impurity content and good heat resistance, and can be used for preparing the spinning-grade all-aryl polynaphthyl ester resin. The melt fluidity is good, the shear thinning phenomenon is more obvious, and the method can be directly used for preparing the polynaphthalene ester fiber.

A method of synthesizing the benzoate salt of 5-MeO-DMT comprising the step of treating the hydrochloride salt of 5-MeO-DMT with a base, prior to the addition of benzoic acid.

The invention relates to a polyorganosilicone cyclophosphazene modified epoxy resin and a preparation method thereof, and belongs to the field of flame retardant materials, and the preparation method of the polyorganosilicone cyclophosphazene flame retardant comprises the following steps: taking hexachlorotripolyphosphazene, p-hydroxybenzaldehyde, p-aminobenzoic acid, DOPO and diphenyl silanediol as raw materials, and carrying out four-step reaction to prepare the polyorganosilicone cyclophosphazene modified epoxy resin. The preparation method comprises the following steps: by taking m-phenylenediamine as a curing agent, adding the series gradient polyorganosilicone cyclophosphazene flame retardant into the epoxy resin, and curing twice to obtain the modified epoxy resin. The preparation method is mainly used for preparing the polyorganosilicone cyclophosphazene flame retardant and the polyorganosilicone cyclophosphazene modified epoxy resin.

A method of synthesizing the benzoate salt of 5-MeO-DMT comprising the step of treating the hydrochloride salt of 5-MeO-DMT with a base, prior to the addition of benzoic acid.

The invention belongs to the technical field of microorganisms, and particularly relates to pseudomonas monteilii BDLZ-3 and application thereof in relieving continuous cropping obstacles of crops. The invention discloses a strain of pseudomonas monteilii BDLZ-3, the preservation number of which is CGMCC (China General Microbiological Culture Collection Center) No.34349. The pseudomonas monteilii BDLZ-3 is separated and screened from the nature for the first time, phenolic acid autotoxic substances generated in the ginseng continuous cropping obstacle process can be efficiently degraded, the degradation rate of benzoic acid can reach 95.36%, various phenolic acids such as vanillic acid, cinnamic acid, palmitic acid and gallic acid can be effectively degraded, and the degradation spectrum is wide; when the pseudomonas monteilii BDLZ-3 is applied in a field, the content of benzoic acid in soil can be effectively reduced, meanwhile, the occurrence of ginseng root diseases can be controlled to a certain extent, the prevention and treatment effect reaches 41.23%, the growth indexes such as root length and root thickness are remarkably improved, and the yield increasing effect is achieved.

The invention provides a preparation method of tert-butyl peroxybenzoate, and relates to the technical field of tert-butyl peroxybenzoate synthesis, the preparation method comprises the following steps: S1, pumping liquid caustic soda and water into a reaction kettle; s2, tert-butyl hydroperoxide is added into the reaction kettle for a salt forming reaction; s3, after the salt forming reaction is finished, benzoyl chloride and a catalyst are added for a condensation reaction, and a tert-butyl peroxybenzoate crude product is obtained; and S4, carrying out alkali washing and water washing on the tert-butyl peroxybenzoate crude product, and adding a stabilizer and a cosolvent to obtain a finished product. The preparation method can improve the yield and stability of tert-butyl peroxybenzoate.

The invention discloses a fermentation medium for regulating and controlling a clostridium aerovorans target product and a fermentation method of the clostridium aerovorans target product. The medium comprises a basic component and a regulating component, the basic components comprise ammonium chloride, potassium chloride, magnesium sulfate heptahydrate, sodium chloride, monopotassium phosphate, yeast powder, calcium chloride dihydrate, sodium selenite, nickel chloride hexahydrate, biotin, folic acid, pyridoxine hydrochloride, thiamine, riboflavin, nicotinic acid, D-calcium pantothenate, cobalamin, para aminobenzoic acid and lipoic acid; the adjusting component comprises sodium tungstate, ferrous sulfate and sodium molybdate, sodium tungstate and ferrous sulfate have a forward adjusting effect on increasing the yield of acetic acid, ethanol and butanol in the target product, and sodium molybdate has a reverse adjusting effect on the target product. By optimizing the proportion of trace elements in the culture medium, the clostridium metabolism efficiency is improved, synthesis of a target product is regulated and controlled, and the method is particularly suitable for industrial production of acetic acid, ethanol, butanol and the like.

The invention discloses an all-solid-state composite dry conductive agent and a preparation method thereof, and belongs to the technical field of batteries. The all-solid-state composite dry conductive agent is prepared by the following steps: uniformly mixing carbon nanotubes, high-dispersion carbon black and graphene to obtain a primary mixture; then preparing a uniformly dispersed glue solution from the composite dispersant and water; and then adding the primary mixture into the glue solution, uniformly mixing, sanding, homogenizing, drying and crushing to obtain the product, the high-dispersion carbon black is obtained by oxidizing carbon black to form active groups such as carboxyl and hydroxyl on the surface of the carbon black, halogenating acyl and then reacting with lithium 2, 5-diaminobenzene sulfonate. The preparation method comprises the following steps: grafting histidine ester into carboxymethyl cellulose by using propylene glycol diglycidyl ester as a cross-linking agent, then introducing allyl-1, 3-sultone, then copolymerizing with lithium 2-acrylamido-2-methylpropanesulfonate and 3-aminobenzoic acid allyl ester protected by fluorenylmethoxycarbonyl, and then deprotecting to obtain the composite dispersant.

The invention provides a preparation method of a Janus material for simultaneous screening of protein phosphorylation and palmitoylation modification, and belongs to the technical field of magnetic material synthesis. The method comprises the following steps: firstly, preparing MCeO2; the preparation method comprises the following steps: mixing MCeO2, hexadecyl trimethyl ammonium bromide and ammonia water to obtain a mixed solution, adding 1, 2-bis (triethoxysilane) ethane into the mixed solution for reaction to obtain a product, and dispersing the product into an NH4NO3 solution for reflux reaction to obtain Janus MCP; the preparation method comprises the following steps: reacting Janus MCP with a silane coupling agent, dissolving aminated Janus MCP and 4-ethylene sulfonyl benzoic acid in a buffer solution containing EDC and NHS, and reacting to obtain the Janus material. The preparation method is reliable, the material performance is stable, and the enrichment efficiency of the magnetic Janus on target peptide fragments (phosphorylated peptide fragments and palmitoylated peptide fragments) is remarkably improved.

The invention belongs to the technical field of insulator materials, and particularly relates to an insulating busbar and a preparation method thereof. The preparation method of the insulating busbar comprises the following steps: coating glue on the surface of a busbar base material, and drying to obtain a busbar with a bonding layer; the preparation method comprises the following steps: mixing 40 to 60 parts of silicon resin, 20 to 40 parts of grafted silicon dioxide, 10 to 20 parts of aluminum oxide and 2 to 4 parts of 2, 5-dimethyl-2, 5-bis-(tert-butylperoxy) hexane, so as to obtain a sizing material; placing the busbar with the bonding layer in a mold, then adding a sizing material, and pressing to obtain an insulating busbar; the preparation method of the grafted silicon dioxide comprises the following steps: stirring m-aminobenzoic acid and 3-aminopropyltriethoxysilane for reaction to obtain a grafting solution, and adding silicon dioxide into the grafting solution for grafting reaction to obtain the grafted silicon dioxide.

To provide a disposal method for a recyclable material containing polyester (recyclate).SOLUTION: A disposal method for recyclate comprises: providing a recyclable material containing polyester; performing a first depolymerization step, comprising mixing the recyclable material and oligo-bis(2-hydroxyethyl) terephthalate (o-BHET) for reaction and extrusion depolymerization to at least obtain or produce poly-bis(2-hydroxyethyl) terephthalate (p-BHET); and performing a second depolymerization step, comprising mixing the p-BHET and a depolymerization solution for chemically depolymerization to at least obtain or produce monomer-bis(2-hydroxyethyl) terephthalate (m-BHET).SELECTED DRAWING: Figure 1

A high-strength PA6 composite material and a preparation method therefor, the PA6 composite material comprising, in parts by mass, 80-95 parts of caprolactam, 1-3 parts of benzoic acid and 10-30 parts of a modification additive. The benzoic acid is used for improving the tensile strength of the composite material, and the modification additive is used for enhancing the impact resistance of the composite material. Terephthalic acid and m-xylylenediamine undergo a reaction to generate m-xylylenediamine terephthalate, which is then subjected to a polycondensation reaction with caprolactam, so as to introduce same into the backbone of a PA6 molecule and modify the PA6 resin. The modified PA6 resin has remarkably improved tensile strength and impact resistance, so that the application range of the PA6 composite material can be greatly expanded.

A composition, and uses and methods of using the composition, said composition comprising: (a) at least 0.1 wt. % of a retinoid component selected from retinol, retinal, retinoic acid or combinations thereof; (b) one or more water-soluble antioxidant; (c) one or more oil-soluble antioxidant; (d) from 0.1 to 3 wt. % of a thickener component comprising polyacrylic acid, polyacrylate, polyacrylamide, polysaccharide or combinations thereof; and (e) from 4 to 20 wt. % of an emollient component comprising a benzoic acid ester, a silicone oil, a triglyceride or a combination thereof.

The invention relates to the technical field of fabric preparation, in particular to environment-friendly breathable polyester silk fabric and a preparation process thereof. The preparation method comprises the following steps: preparing an epoxy polyurethane emulsion by taking glycidyl as an end-capping reagent; eugenol and phenyl dichlorophosphate are used as raw materials to react, and m-chloroperoxybenzoic acid is used as an oxidizing agent to prepare an epoxy flame retardant; the preparation method comprises the following steps: carrying out reaction on N, N-diethylaminopropyl methyl dimethoxy silane and epoxy chloropropane to obtain epoxy organosilicon quaternary ammonium salt; mixing the epoxy-based polyurethane emulsion, the epoxy-based flame retardant, the epoxy-based organosilicon quaternary ammonium salt and the curing agent, and modifying the polyester silk; preparing bio-based spinning fibers from a mixed solution of a carboxymethyl cellulose solution and a chitosan solution through an electrostatic spinning technology, and then blending the bio-based spinning fibers with the modified polyester to obtain the polyester fabric. The polyester silk fabric prepared by the method has good flame retardant property, antibacterial property and air permeability, and part of materials are renewable materials, so that the polyester silk fabric is economical and environment-friendly and meets the requirement of green development.

The invention discloses a fibrous membrane prepared based on in-situ growth and application of the fibrous membrane in toluene adsorption, and belongs to the technical field of functional textiles. The method for preparing the fiber membrane based on in-situ growth comprises the following steps: (1) adding 2-aminoterephthalic acid and polyacrylonitrile into a solvent, and uniformly mixing to obtain a spinning solution; (2) performing electrostatic spinning on the spinning solution, and drying to obtain a fiber membrane; (3) placing the fiber membrane in an ethylene glycol solution, adding ethylenediamine, and carrying out thermal crosslinking; after the thermal crosslinking is finished, washing and drying to obtain a crosslinked fiber membrane; and (4) placing the cross-linked fiber membrane in a solvent, adding zirconium oxychloride, 2-aminoterephthalic acid and benzoic acid, and carrying out in-situ growth to obtain the fiber membrane prepared based on in-situ growth. The fiber membrane prepared on the basis of in-situ growth is high in methylbenzene adsorption capacity and can be recycled.

The invention relates to a composition with anti-allergy, repairing and moisturizing effects. The composition is prepared from fibronectin, kava pepper leaf / root / stem extract, ectoine, hydroxyphenyl propionamide benzoic acid, wheat fine powder lipid and bio-saccharide gum-1. The specific components are matched with one another, inflammatory response can be inhibited from multiple aspects, the skin can be sufficiently relieved, the redness phenomenon is reduced, meanwhile, the skin barrier is enhanced and repaired, long-term moisturizing is achieved, and the excellent anti-allergy, repairing and moisturizing effects are achieved.