14 results about "Ethylparaben" patented technology

This invention belongs to the field of pharmaceutical chemistry, and specifically relates to a compound antifungal cream containing the traditional Chinese medicine ingredient tryptamine ketone and its application. The invention comprises the following components, with the following percentage content: stearic acid 10%~16%, glyceryl monostearate 3%~7%, liquid paraffin 5%~9%, tryptamine 0.1%~0.01%, terbinafine hydrochloride 0.00625%~0.000625%, glycerin 4%, triethanolamine 2%~6%, ethylparaben 0.5%, and the balance being purified water or distilled water. This invention is highly effective, low in toxicity, and exhibits low drug resistance.

The invention relates to the technical field of traditional Chinese pharmacology, and particularly discloses an external liquid containing lime and alum for astringing sores and a preparation method of the external liquid. The external liquid containing lime and alum for healing sores is prepared from the following raw materials: lime, alum, water, a thickening agent, a cortex phellodendri extract, carbonized sanguisorba root powder, borneol and a pH regulator. The preparation method comprises the following steps: S1, preparing lime milk; s2, preparing an alum solution; s3, mixing reaction; s4, performing curing treatment; s5, blending; s6, refining: filtering the mixture obtained in S5, adding borneol and ethylparaben into the filtrate before filtering, and uniformly stirring to obtain the external liquid for healing sore. The external liquid containing lime and alum for healing sores can be used for treating various skin injuries such as skin ulcers, wounds, burns, eczema and postoperative wounds, and has the advantages of efficient astringency and hemostasis, antisepsis and anti-inflammation, promotion of wound healing, good system stability, comfort in use and high safety.

This invention discloses a skin cream for chapped hands and feet and its preparation process, belonging to the field of skin cream preparation technology. The skin cream is composed of ginseng leaf and stem extract, royal jelly, glycerin, octadecanol, glyceryl stearate, liquid paraffin, sodium lauryl sulfate, ethylparaben, fragrance, and purified water in a specific mass ratio. Its preparation process includes steps such as heating and melting the oil and water phases separately, emulsifying and stirring, cooling and adding active ingredients, and aging. This product, through the synergistic effect of moisturizing and active repairing ingredients, can effectively relieve dry and cracked skin, promote healing, and has the advantages of stable formula, gentle skin feel, and high safety.

The invention provides a Chinese pulsatilla root oral liquid preparation and a preparation method thereof.The Chinese pulsatilla root oral liquid preparation per liter comprises 300 g of Chinese pulsatilla roots, 150 g of rhizoma coptidis, 300 g of cortex fraxini, 225 g of cortex phellodendri, 50 ml of PEG-400, 20 g of xanthan gum, 20 g of hydrophilic colloidal silicon dioxide, 5 g of neotame, 1.5 g of ethylparaben and the balance auxiliary materials. The palatability is better, and the clinical effect is obviously improved compared with that of other similar products.

This application relates to the technical field of daily cosmetics, specifically disclosing a hair-repairing and conditioning wheat composition, a cosmetic containing the composition, and a preparation method thereof. The hair-repairing and conditioning composition comprises the following components in parts by weight: 0.003-0.006 parts of a mixture of hydrolyzed wheat protein / phenoxyethanol / methylparaben / ethylparaben / ethylhexylglycerin / propylene glycol / water; 0.03-0.05 parts of a mixture of wheat germ oil glycerides / glyceryl stearate; and 2.4-2.6 parts of a mixture of cationic surfactant / ethanol. The wheat germ oil glycerides selected in this application are rich in linoleic acid and vitamin E, exhibiting a stronger affinity for cationic surfactants, enabling the formation of a stable "cationic-oil complex" for efficient deposition. Simultaneously, the wheat germ oil glycerides are homologous to hydrolyzed wheat protein, forming a synergistic repair mechanism of first penetrating and filling, then sealing and locking in moisture, thus improving the hair-repairing and conditioning effect.

This invention, entitled "A Method for Preparing an Antiepileptic Carbon Dot Suspension," belongs to the field of pharmaceutical technology. It relates to a method for preparing a nanoparticle suspension and provides a carbon dot suspension for treating epilepsy. The raw materials and excipients of the suspension include: carbon dots from human hair, stabilizers, flavoring agents, and preservatives. The suspension of this invention exhibits stable properties, simple excipient composition and preparation process, and excellent taste. The most preferred formulation is: 5g of carbon dots from human hair, 0.125% CMC-Na, 0.05% ethylparaben, and 2.5% sucrose.

The invention discloses a chemical detection method for oculent.The chemical detection method relates to the technical field of chemical analysis, the oculentcomprises ganciclovir, yellow vaseline, lanolin, liquid paraffin, white vaseline, glycerin, ethylparaben and vitamin E. The method comprises the following steps that (a) the content of ganciclovir in the oculent.The content of ganciclovir in the oculent.The content of ganciclovir in the oculentis is measured through a high performance liquid chromatography; (b) carrying out quality control on the lanolin raw material, namely measuring an acid value, a saponification value and a peroxide value; (c) carrying out wool fat related quality monitoring on the oculentum finished product, wherein the wool fat related quality monitoring comprises determination of a peroxide value; according to the method, chromatographic conditions are optimized, an exclusive impurity detection method is established, and raw materials are associated with finished product detection, so that the quality control problem of ganciclovir oculentum is solved.

The invention provides a method for determining the content of ethylparaben in urea vitamin E cream. According to the method, HPLC (High Performance Liquid Chromatography) is adopted to detect a test solution, a chromatographic column takes octadecylsilane chemically bonded silica as a filling agent, a solution of acetonitrile and 0.5% acetic acid in a volume ratio of (18: 82)-(30: 70) is taken as a mobile phase, and good separation of an ethylparaben peak, an auxiliary material peak and vitamin E can be realized. The determination method disclosed by the invention is high in accuracy, good in precision, strong in specificity and good in stability.

This invention belongs to the field of pharmaceutical preparations, and particularly relates to a dimethicone emulsion and its preparation method. The preparation method provided by this invention includes the following steps: a) grinding and mixing dimethicone and silica at 100-140°C to obtain an oil phase mixture; b) mixing sodium saccharin, ethylparaben, and water, and then mixing with sodium carboxymethyl cellulose to obtain an aqueous phase mixture; c) mixing the oil phase mixture, polysorbate 80, and sorbitan oleate, and then mixing with a portion of the aqueous phase mixture, followed by homogenization to obtain a primary emulsion; d) mixing the remaining aqueous phase mixture, an ethanol solution of butylated hydroxytoluene, and a fragrance, and then mixing with the primary emulsion, finally adding water to make up to a fixed volume and mixing to obtain the dimethicone emulsion. The preparation method provided by this invention has a short production cycle and high production efficiency, and the resulting dimethicone emulsion product has excellent defoaming ability and quality stability.

The invention discloses a preparation method and a quality detection method of a Jianer food retention removing patch, and belongs to the technical field of traditional Chinese medicine preparations, the preparation method comprises the following steps: crushing clove and pepper accounting for about 1 / 3 of the total amount of pepper into finest powder, and mixing to obtain a fine powder mixture; crushing fructus gardeniae, semen armeniacae amarae and the remaining pepper into coarsest powder, cutting fresh fistular onion stalks into sections, and mixing the sections with the coarsest powder to obtain a coarse powder mixture; carrying out reflux extraction on the coarse powder mixture by using 90% ethanol, and combining filtrates; recovering ethanol in the filtrate, and concentrating to obtain clear paste with the relative density of 1.16-1.20; and adding ethylparaben into the clear paste, uniformly stirring, adding the fine powder mixture, and uniformly stirring again to prepare the lozenge with specified weight. According to the invention, a preparation process and a quality control method are combined to form a complete technical scheme, so that the problem of unstable product quality possibly existing in the prior art is solved, and a product with more reliable curative effect and higher safety is provided for clinic.

To provide a grape sap which can stably be formulated in cosmetics and quasi-drugs by a prescription for suppressing the amount of a preservative to the minimum unlike a combination of an organic solvent such as 1, 3-butylene glycol, methyl p-hydroxybenzoate (methylparaben), ethyl p-hydroxybenzoate (ethylparaben) or phenoxyethanol with a preservative, and to provide cosmetics and quasi-drugs formulated with the grape sap.SOLUTION: Without using an organic solvent such as 1, 3-butylene glycol, methyl p-hydroxybenzoate (methylparaben), ethyl p-hydroxybenzoate (ethylparaben) or phenoxyethanol, the preservability of the grape sap can be enhanced by the baked powder of the scallop and the plant extract having the antiseptic auxiliary action, and the grape sap can further stably be formulated with cosmetics and quasi-drugs.SELECTED DRAWING: None

The invention provides amitriptyline hydrochloride emulsifiable paste as well as a preparation method and application thereof, and belongs to the technical field of medicines. The amitriptyline hydrochloride emulsion is prepared from the following components in parts by mass: 3 to 8 parts of amitriptyline hydrochloride, 5 to 10 parts of glycerol, 3 to 8 parts of octadecanol, 3 to 8 parts of hexadecanol, 0.5 to 2 parts of ethylparaben, 2 to 5 parts of white vaseline, 0.5 to 2 parts of lauryl sodium sulfate, 12 to 20 parts of dimeticone, 0.5 to 2 parts of laurocapram, 1 to 5 parts of OP-10 and 40 to 67.5 parts of water. When a neuropathic pain model mouse is smeared with the amitriptyline hydrochloride emulsifiable paste, the symptom of the neuropathic pain of the mouse can be improved, the amitriptyline hydrochloride emulsifiable paste can quickly play a role in easing pain, and repair of injured nerves can be promoted through long-term administration.

The invention provides a radiation shielding covering and a preparation method and application thereof. The radiation shielding covering provided by the invention comprises carrier cream and bismuth oxide, wherein the mass content of the bismuth oxide in the radiation shielding covering is 5-85%; the carrier cream is prepared from ethylparaben, xanthan gum, cetostearyl alcohol, albolene, lauryl sodium sulfate, phenoxyethanol and deionized water; the mass ratio of the ethylparaben to the xanthan gum to the cetostearyl alcohol to the white vaseline to the lauryl sodium sulfate to the phenoxyethanol is 1 to (0.4 to 0.6) to (7.5 to 8.5) to (7.5 to 8.5) to (0.9 to 1.1) to (0.9 to 1.1); the mass content of the deionized water in the carrier cream is 80.5%-93.5%. Bismuth oxide is selected as a radiation shielding component and acts together with the carrier cream with specific components, so that the radiation shielding effect of the radiation shielding covering is improved.

The invention discloses a high-glucose response type double-layer hydrogel dressing for diabetic wounds and application of the high-glucose response type double-layer hydrogel dressing. The dressing is composed of an inner layer and an outer layer which are complementary in function, wherein the inner layer is mainly composed of polyvinyl alcohol, phenylboronic acid grafted silk fibroin and tannic acid, and a cross-linked network is formed through dynamic boric acid ester bonds and hydrogen bonds; the outer layer is mainly prepared from methacrylated hyaluronic acid, salvianolic acid B, polydimethylsiloxane, glycerol and sodium ethylparaben, and a stable framework is formed through photochemical crosslinking. The inner layer structure can respond to a high-glucose microenvironment of a wound and intelligently release tannic acid, so that the adhesion of the dressing is enhanced, and the anti-inflammatory and anti-oxidation effects are achieved; and the outer layer structure provides long-acting moisturizing, mechanical supporting and physical barrier functions and can release salvianolic acid B in a controlled manner to promote angiogenesis. The double-layer hydrogel structure disclosed by the invention realizes space-time drug delivery and targeted treatment at different stages in a diabetes wound healing process.