52 results about "Lamiophlomis rotata" patented technology

The invention relates to compound lamiophlomis rotata medicinal toothpaste, which is prepared from the following raw materials in percentage by weight: 10 to 20 percent of lamiophlomis rotata extract, 2 to 10 percent of golden thread extract, 3 to 10 percent of gypsum powder, 2 to 10 percent of Meconopsis extract, 1 to 5 percent of moxa leaf extract and 45 to 82 percent of substrate. Meanwhile, the invention discloses a preparation method for the medicinal toothpaste. The compound lamiophlomis rotata medicinal toothpaste has the effects of common toothpaste of clearing residual foods in an oral cavity and cleaning dirt on tooth surfaces to maintain balanced pH value in the oral cavity of a human body, can effectively prevent and treat gum bleeding, gingivitis, periodontitis, gum swelling and pain, dental ulcer and dental decay, and has the effects of desensitizing, relieving pain and removing halitosis to comprehensively prevent and treat odontopathy and oral diseases.

The medicine plant material Lamiophlomis rotata or its root is alcohol or water extracted to obtain the extract liquid, and the extract liquid is further separated and purified to obtain active extract, which contains total flavone in 50-80 wt% counted in rutin and luteolin in 1.0-5.0 wt%. The present invention has raised curative effect and reduced taken amount, and is used in treating various kinds of pain, hemorrhage, etc. The active extract may be added with pharmaceutically acceptable supplementary material to prepare various orally taken preparation, preferably dripping pill.

The invention provides a method for simultaneous detection of iridoid glycoside, phenylethanoid glycoside, flavone and dicaffeoyl ingredients in lamiophlomis rotate. In the detection method, the peak amount is large, separation degree is high, a base line is stable, the lamiophlomis rotate can be effectively detected, and new selection is provided for guaranteeing of medicine material quality. The iridoid glycoside, phenylethanoid glycoside, flavone and dicaffeoyl ingredients are detected under the same chromatographic condition for the first time, seven specific compounds are identified, and the quality of lamiophlomis rotate medicine materials can be comprehensively and accurately controlled.

The invention discloses a UPLC fingerprint spectrum detection method of lamiophlomis rotata (Benth.)Kudo and preparations thereof. The method includes the following steps of: (a) the preparation of areference substance solution; (b) the preparation of a test solution; (c) the provision of UPLC detection conditions; (d) the formation of a standard fingerprint spectrum with sesamoside, caffeic acid, chlorogenic acid, shanzhiside methyl ester, loganin, 8-O-acetyl shanzhiside methyl ester, forsythiaside B, galuteolin, verbascoside, Isoacteoside and the like adopted as reference peaks; and (e) thequality control of the fingerprint spectrum. According to the method, during test solution preparation, an extraction solvent is environment-friendly. The method is simple. Compared with a traditional HPLC method, the method is more convenient and rapider, and save energy and reduce energy consumption. The separation effect of the characteristic peaks of the fingerprint spectrum of the lamiophlomis rotata (Benth.)Kudo and the preparation thereof is good; and characteristic compositions and medicinal compositions can be reserved completely. The method has the advantages of good repeatability,high stability, high precision and strong specificity. The method can accurately and quickly control the lamiophlomis rotata (Benth.)Kudo and the preparations thereof.

The invention discloses a rapid seedling culturing method for lamiophlomis rotata. The rapid seedling culturing method for lamiophlomis rotata comprises the following steps that (1) a seedling culturing pool is built or a seedling culturing basin is taken, and water is added; (2) a seedling culturing plate is taken and sterilized, a seedling culturing matrix is put in the seedling culturing plate, lamiophlomis rotata seeds processed in advance are sowed, then the seedling culturing plate with the sowed seeds is obtained, the seedling culturing matrix comprises turf and perlite, and the weight ratio between the turf and the perlite is (5-7):(3-5); (3) the seedling culturing plate with the sowed seeds obtained in the step (2) is arranged in the seedling culturing pool or the seedling culturing basin obtained in the step (1) for culturing, after seedlings come out, fertilizer is added to the water in the seedling culturing pool or the seedling culturing basin until the concentration of nitrogen is 150-250g / L, the concentration of phosphorus is 10-40g / L and the concentration of potassium is 200-300g / L, and the fertilizer is added every ten days; (4) culturing is finished until the height of the overground parts of the lamiophlomis rotata seedlings is 2-3cm and the height of the underground parts of the lamiophlomis rotata seedlings is 5-10cm. The rapid seedling culturing method for lamiophlomis rotata is easy and convenient to implement, high in emergence rate of the seedlings, short in time and low in cost. The cultured lamiophlomis rotata seedlings grow fast, are orderly and healthy, and have good economic benefits.

The invention relates to lamiophlomis rotata cataplasm and a preparation method thereof. The cataplasm comprises lamiophlomis rotata extracts, appropriate matrix and auxiliary materials. The lamiophlomis rotata cataplasm has excellent therapeutic effects of clearing heat, eliminating tumescence, activating blood circulation and relieving pain without causing any adverse reaction.

The invention provides a capsule preparation for treating bruises as well as bleeding and easing pain and a preparation method and uses thereof. The capsule preparation provided by the invention is prepared from 1 part of lamiophlomis rotata and 0.1-50 parts of Panax pseudo-ginseng, wherein a lamiophlomis rotata extractive serves as a bond, and a Panax pseudo-ginseng extractive and a pharmaceutically acceptable loading agent, such as starch, serve as basic material to fabricate pellets. The invention also provides a method for preparing the capsule preparation and applications of the capsule preparation in preparing medicines for treating bruises as well as bleeding and easing pain. Meanwhile, the invention also provides the lamiophlomis rotata extractive and the Panax pseudo-ginseng extractive which are prepared by using the invention.

The invention discloses a traditional Chinese medicine formula for treating rheumatism. The traditional Chinese medicine formula is prepared from the following raw materials in parts by weight: 15-25 parts of caesalpinia minax hance, 5-15 parts of loose knot, 10-25 parts of lamiophlomis rotata, 10-30 parts of radix zanthoxyli, 20-30 parts of alangium platanifolium, 15-30 parts of radix clematidis, 10-30 parts of litsea cubeba leaves, 50-80 parts of wild chrysanthemum flower stem, 15-25 parts of saposhnidoviae radix, 10-30 parts of camphor root, 10-25 parts of pepper, 15-20 parts of folium mori, 15-25 parts of honeysuckle stem, 10-35 parts of motherwort, 15-25 parts of perilla leaves, 25-35 parts of hawthorn root, 10-20 parts of kalimeris indica, 20-25 parts of rhizoma nardostachyos and 15-20 parts of common bluebeard herb.

The invention discloses a hemostatic antibacterial healing-promoting medical dressing containing lamiophlomis rotata iridoid glycoside active ingredient composite medical ACF and belongs to the technical field of preparation of medical dressings. The medical dressing is composed of the following components in percentage by weight: 1-20% of lamiophlomis rotata iridoid glycosides, 0.01-1% of hexadecyl trimethyl ammonium chloride, 1-5% of polyvinyl alcohol or collagen and the balance of a medical ACF matrix. The lamiophlomis rotata iridoid glycoside active ingredients and polyvinyl alcohol or collagen and the like are combined to be prepared into a solution dosage form and a gel dosage form, and the dosage forms are compounded with medical ACFs so as to prepare a series of external medical dressings. By utilizing the strong effects of the ACF for adsorbing wound exudates, activating a clotting mechanism and accelerating hemostasis, the 'synergistic effect' between the two is achieved, and the medical dressing can be used for treating infectious wounds, surgical trauma bleeding and the like, has excellent hemostatic antibacterial healing-promoting effects and also has wide application prospects. The medical dressing disclosed by the invention is reasonable in formula and convenient in preparation and has the effects of controlling the wound infection and promoting healing of the wound. The hemostasis models for wounds at artery and ventral aorta in ears of large-ear white rabbits and human-mouse livers prove that the effective rate reaches 95% or higher.

The invention relates to a lamiophlomis rotata externally-applied preparation which adopts raw materials comprising a lamiophlomis rotata thick paste and an externally-applied substrate, wherein the externally-applied substrate comprises a framework material and auxiliary materials, and the framework material is a high molecular material, such as natural rubber, or mixed rubber comprising natural rubber and styrene-butadiene rubber, or a thermoplastic high molecular material; the preparation method of the lamiophlomis rotata externally-applied preparation comprises the following steps: firstly, extracting, purifying and concentrating the crude drug of lamiophlomis rotata to prepare the lamiophlomis rotata thick paste and then adding other raw materials to prepare a lamiophlomis rotata rubber ointment, wherein, macroporous resin is used for carrying out purifying. In the raw materials, menthol, wintergreen oil, borneol, camphor and the lamiophlomis rotata are matched and used according to the specific proportion of the invention, which changes the microstructure of the skin, increases the percutaneous speed and the percutaneous quantity of the medicine, improves the blood circulation and enhances the release degree of the active components of the medicine in the ointment; the effective components of the lamiophlomis rotata thick paste prepared by refluxing and extracting through adopting an ethanol solution have high proportion and high purity, so that the lamiophlomis rotata externally-applied preparation has high medicine effect and also has good stability.

The invention discloses a method for determining phenylpropanoid glycoside substances in a Tibetan medicine Lamiophlomis rotate. According to the invention, the characteristic that phenylpropanoid glycoside can be hydrolyzed to release phenethanol and cinnamic acid compounds is used, various types of phenethanol and cinnamic acid compounds in Lamiophlomis rotata are separated by a high performance liquid chromatography method and determined by using an external standard method, so that accurate determination of phenylpropanoid glycoside substances in the Lamiophlomis rotate can be achieved.

The invention provides a formula for mouth wash containing a Tibetan medicine lamiophlomis rotata and a preparation method thereof. The mouth wash comprises 5-10% of Tibetan medicine lamiophlomis rotata extract iridoid glycoside liquor, 0.05-0.30% of benzalkonium chloride, 4-7% of cineole, 30-50% of methyl salicylate, 0.45-0.55% of menthol, 5-25% of sorbitol, 5-25% of ethyl alcohol, 0.45-0.55% of lauryl sodium sulfate (SDS), 0.8-1.8% of benzoic acid, 0.25-0.35% of glycerol, 0.05-0.15% of soluble saccharin, 0.5-1.5% of edible essence and the balance of water. The preparation method comprises the following steps: uniformly mixing the components of the mouth wash, adding distilled water, further stirring and mixing into a clear liquid, thereby acquiring the mouth wash. The mouth wash provided by the invention has multiple functions of blood clearing, hemostasis, antibiosis and anti-inflammation; the characteristics of the traditional mouth wash are kept; the lamiophlomis rotate liquor is added, so that the mouth wash has the functions of hemostasis, antibiosis, anti-inflammation and breath refreshing and is capable of effectively relieving the symptoms, such as, bleeding gums, periodontitis and swollen sore throat.

The invention belongs to the technical field of traditional Chinese patent medicaments, and in particular relates to a medicament for treating cervical spondylosis and a preparation method thereof. The medicament is mainly used for solving problems of the existing medicaments for treating cervical spondylosis such as single effect, strong side effects, high possibility of complications and the like. The medicament is prepared from astragalus root, red sage root, gastrodia tuber, white peony root, uncaria rhynchophylla, kudzuvine root, szechuan lovage rhizome and lamiophlomis rotata. The preparation method comprises the following steps: taking the red sage root and the uncaria rhynchophylla, carrying out reflux extraction with ethanol for 2-4 times, and concentrating the extracting solution to obtain clear paste I; taking dregs of the extracted red sage root and uncaria rhynchophylla, distilling to remove the ethanol, mixing the dregs with the astragalus root, the gastrodia tuber, the white peony root, the kudzuvine root, the szechuan lovage rhizome and the lamiophlomis rotata, decocting the mixed materials with water for 2-4 times, merging decoction, filtering, and concentrating the obtained filtered liquor to obtain clear paste II; and mixing the clear paste I and the clear paste II, crushing the mixed clear paste to obtain extract powder, adding lactose and aspartame to the extract powder, evenly mixing to form particles, sterilizing and packaging to obtain the medicament. The medicament for treating cervical spondylosis has the advantages of definite curative effect, comprehensive regulation function, low cost, no toxic side effects and the like.

The invention belongs to the technical field of medicine, and provides a Tibetan pharmaceutical, lamiophlomis rotata total flavone extractive as well as an extracting method and the application thereof. The method uses Tibetan pharmaceutical lamiophlomis rotata as raw material, uses ethanol prepared by alkalescence solution with different pH values as solvent, and adopts a backflow method for extracting. After two steps of decontamination and the separation and enrichment of macropore resin, the total flavone extractive with the purity being 50 to 95 percent can be obtained from extracting solution. In the process of separation and enrichment, after the two steps of decontamination and the separation and enrichment of macropore resin, a sample with high purity can be obtained and the purity of the total flavone in the sample can be 95 percent at most, wherein, the percentage is higher than the number reported in documents. The invention also provides the application of the total flavone as pain killer medicine and stanch medicine. The paper optimizes and improves the extracting method so as to increase the transfer rate of effective ingredient, improve the utilization rate of medicinal materials and save a great amount of cost effectively, thus having high economical benefit.

The invention relates to a lamiophlomis rotata capsule and a preparation method thereof, belongs to the technical field of medicines, and in particular belongs to the technical field of medicinal preparations. The lamiophlomis rotata soft capsule consists of a content and a soft capsule shell, wherein 0.063-0.078mg of rutin which contains total flavonoids with a molecular formula of C27H30O16 is contained in each mg of the content. The lamiophlomis rotata capsule has the remarkable characteristics of stable property, long storage time, short disintegration, quick dissolution and the like which are not possessed by common soft capsules.

The invention discloses application of a Tibetan medicine composition to preparation of a medicament for treating bronchial asthma. The Tibetan medicine composition consists of the following raw materials in parts by weight: 5 to 15 parts of lamiophlomis rotata, 2 to 10 parts of whin, 15 to 60 parts of turmeric, 7 to 20 parts of sichuan pepper, 5 to 15 parts of buffalo horn, 15 to 40 parts of myricariagermanica, 0.1 to 2.5 parts of safflower, 0.1 to 5 parts of borneol and 0.1 to 5 parts of camphor. In the invention, by further research on the pharmacology of the traditional Tibetan medicine composition, the Tibetan medicine composition disclosed by the invention is found to have good curative effect in treating bronchial asthma. Moreover, pure natural wild herbs produced in the Qinghai-Tibet Plateau are adopted in the Tibetan medicine composition. The Tibetan medicine composition is not added with any chemosynthetic stabilizer, has no toxic or side effects on a human body, is safe andeffective and is suitable for various people.

The invention relates to the technical field of active substance extraction, in particular to a preparation method of lamiophlomis rotata extracts and the prepared extracts thereof. According to the preparation method of the lamiophlomis rotata extracts, the medicinal herb of the lamiophlomis rotate is extracted with water and an orthogonal test method is utilized to find suitable extraction parameters. The extraction and conversion rate of effective components can be improved, and the quality of extracts is also improved. Experiments show that the extraction effects are best when 30 times ofwater is used to extract the lamiophlomis rotata three times (6: 5: 4) without being powdered for one hour each time at the temperature of 100 DEG C.

The invention provides a Lamiophlomis rotata(Benth.) Kudo preparation and a preparation method thereof. A Lamiophlomis rotata(Benth.) Kudo extract is prepared into a solid dispersion through a hot-melt extrusion technology, the dispersity and specific surface area are increased, leaching of effective components is promoted, the hydrophilicity of medicine is increased, the solubility and dissolving-out speed of the Lamiophlomis rotata(Benth.) Kudo solid dispersion are increased, the bioavailability of the medicine is improved, and medicine curative effect exerting is promoted.

The invention discloses an extraction method for polysaccharide of lamiophlomis rotate. The extraction method comprises the following steps of taking lamiophlomis rotata powder, decoloring, adding water for reflux extraction, and collecting an extracting solution. The invention also discloses a method for detecting the content of the polysaccharide of the lamiophlomis rotate. According to the extraction method for the polysaccharide of the lamiophlomis rotate provided by the invention, the polysaccharide in a lamiophlomis rotate sample can be high-efficiently extracted, and the detection method established on the basis can be used for effectively and accurately detecting the content of the polysaccharide of the lamiophlomis rotate, is good in repeatability, high in accuracy, and capable of objectively reflecting the content of the polysaccharide of the lamiophlomis rotate sample, and has a favorable application prospect.

The invention relates to the technical field of a traditional Chinese medicine preparation, in particular to a pain relieving traditional Chinese medicine composition, and a preparation method and application thereof. The pain relieving traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 3.5 to 10.5 parts ofradix aristolochiae tagalae, 3 to 9 parts of climbing fig, 3 to 9 parts of geckos, 3 to 9 parts of laciniate blumea herbs, 3 to 9 parts of Chinese hydrangeavine root-bark, 3 to 9 parts of safflowers, 3 to 9 parts of frankincense, 3 to 9 parts of myrrh, 3 to 9 parts of radix dipsaci, 3 to 9 parts of natural copper, 3 to 9 parts of lamiophlomis rotata, 2.5 to 7.5 parts of radix cynanchi paniculati, 2.5 to 7.5 parts of radix clematidis, 2 to 6 parts of notopterygium roots, 2 to 6 parts of radix angelicae pubescentis, 2 to 6 parts of radix angelicae sinensis, 2 to 6 parts of pine nodular branches, 1 to 3 parts of radix angelicae, 1 to 3 parts of borneol and 0.5 to 1.5 parts of menthol. The pain relieving traditional Chinese medicine composition is applied to various kinds of pain caused by wind-cold-damp arthralgia, bruise haematoma and the like, and medicine for treating swelling, light-headedness, obnubilation or snake or insect biting. The invention also provides the preparation method of the traditional Chinese medicine preparation.

The invention relates to a drying method for lamiophlomis rotata. The prepared lamiophlomis rotata which is frozen in a drying process has high total saponin content and high total flavonoid content.

The invention discloses technology for improving wild lamiophlomis rotata seed germination. The technology includes: picking infructescence; screening seeds; disinfecting the seed; soaking with warm water and a gibberellin solution; sterilizing and disinfecting; dehydrating the seeds. By utilizing the warm water and the gibberellin solution to soak lamiophlomis rotata seeds, germination rate of lamiophlomis rotata can be increased and can be increased to higher than 75% from 40% when no treatment is performed, and success rate of artificial planting of lamiophlomis rotata is increased greatly.

The invention discloses a separating and purifying method of lamiophlomis rotata total flavonoid. The method comprises the following steps of: (a) crushing root lamiophlomis rotata; (2) putting powdery lamiophlomis rotata into ethanol water according to the ratio that the solid-liquid ratio g / mL of the lamiophlomis rotata to the ethanol water is 1:(5-15), and extracting by ultrasonic sound, wherein the ultrasonic power is 80-100 W; the ultrasonic temperature is 30-60 DEG C; the extraction time is 1-4 hours; and the extraction times is 1-4; (3) filtering an extracting solution, drying in a vacuum condition, and recovering extractum; (4) preparing into a 0.5-2 mg / mL solution from obtained lamiophlomis rotata extractum, and adsorbing by two macroporous adsorption resin mixed beds; (5) washing the adsorbed macroporous adsorption resin mixed beds by distilled water, and then carrying out desorption by adding the ethanol water; and (6) evaporating, concentrating and drying the ethanol desorption solution to obtain the lamiophlomis rotata total flavonoid.

The invention provides ointment containing lamiophlomis rotata as an authentic Tibetan herbal medicine as well as a preparation method and an application of the ointment. The ointment in the formula comprises components as follows: 20%-30% of total iridoid glycoside powder of lamiophlomis rotata, 0.45%-0.55% of camphor, 0.01%-0.05% of borneol, 23%-26% of octadecanol, 20%-25% of albolene, 16%-18% of liquid paraffin, 2.0%-3.0% of sodium lauryl sulfate (SLS), 0.2%-0.3% of ethyl parahydroxybenzoate and a quantity of citronella oil, glycerin and water. The preparation method comprises steps as follows: octadecanol, albolene and liquid paraffin are mixed uniformly and heated to 70-80 DEG C to be molten; ethyl parahydroxybenzoate, SLS, glycerin and water are taken, mixed uniformly and heated to the same temperature, oil phase is added to aqueous phase, the components are stirred until the components are completely emulsified, a mixture is cooled, and a substrate is obtained; the total iridoidglycoside powder of lamiophlomis rotata is weighed, put in a mortar and finely ground, the powder is mixed with camphor, borneol, the citronella oil and the substrate, the mixture is ground uniformly, and the ointment is obtained. The ointment has effects of refreshing and restoring consciousness, relieving swelling and pain, expelling parasite and relieving itching and is applied to treatment oftraumatic injury, arthralgia, myalgia, insect bites and stings, burns and scalds and the like.

A preparation method of a preparation method of a Tibetan medicine Lamiophlomis rotata effervescent tablet belongs to the field of Chinese patent medicinal preparations. The method comprises the following steps: 1, preparing a Lamiophlomis rotata extract; 2, preparing an alkali source wrappage; 3, carrying out dry granulation; 4, tabletting; 5, examining; and 6, packaging. The effective components of the above medicinal material are extracted by adopting an ultrasonic extraction process, so energy saving, time saving and high extraction rate of the effective components are realized; an alkali source indispensable in the preparation is wrapped by PVP (polyvinylpyrrolidone) in advance, so the direct contact of an acid with an alkali in the preparation is avoided, the stability is increased, and it is in favor of solving a sticking problem during tabletting; and the contact time of the extract with the acid, the alkali, water and heat is maximally reduced, so the acceleration of interaction of the extract in the above prescription with the acid source and the alkali source is avoided, the material fluidity is improved, and the production period is shortened.

The invention provides a liquid suspension culture medium for taxus chinensis cells. According to the culture medium, sodium nitrate and dipotassium phosphate serve as a nitrogen source and a phosphorus source respectively, certain calcium chloride is added, and on the basis of the calcium chloride, it is accidentally found that it is helpful to increase cell culture density by adding a certain type of traditional Chinese medicine material of certain ingredients; based on the mentioned beneficial finding, traditional Chinese medicine ingredients such as veronicastrum herbs, lamiophlomis rotata, arcangelisia loureiri, lysimachia foenum-graecum hance, schefflera kwangsiensis, rhizoma anemarrhenae, pericarpium citri reticulatae, kaki calyx and semen allii tuberosi which are originally used for human disease treatment are selected preferentially through experiment means, the obtained culture medium accidentally harvests a remarkable culture effect, the culture density of the taxus chinensis cells is remarkably increased, and meanwhile the growth speed is higher; according to the liquid suspension culture medium, the optimal technical effect is obtained through an innovative technical means, and meanwhile the liquid suspension culture medium is low in cost and easy to implement and thus has good application prospect.

The invention discloses a medical composition for treating mammary gland diseases and preparation method thereof. The medical composition is composed of lamiophlomis rotata, gentiana macrophylla, cluster mallow fruit, curcuma, borneol, camphor and procumbent speedwell. The preparation method of the medical composition comprises the following steps: the lamiophlomis rotata, gentiana macrophylla, cluster mallow fruit, curcuma and procumbent speedwell are respectively decontaminated, cleaned, dried and put for standby; then, the lamiophlomis rotata, gentiana macrophylla and procumbent speedwell are crushed into coarse powder and extracted with water respectively; extract liquids are mixed, and then the mixture is condensed into paste for standby; subsequently, curcuma and cluster mallow fruit are crushed into fine powder for standby; the paste, the fine powder, borneol and camphor are mixed, and finally, common minor ingredients are added to prepare the clinical acceptable medicament form. Cataplasm is the preferable form for the medical composition of the invention. The medical composition has the favorable efficiency on treating mammary gland diseases, especially hyperplasia of mammary glands.

The invention relates to the technical field of Chinese herbal preparations, specifically to a wall-broken Lamiophlomis rotata preparation. The wall-broken Lamiophlomis rotata preparation is prepared by crushing Lamiophlomis rotata into ultrafine powder, then carrying out ethanol-water wet granulation, carrying out extrusion forming at a certain rotating speed and then carrying out drying. The prepared wall-broken Lamiophlomis rotata preparation has high bioavailability, good stability and good disintegration performance.