303 results about "Myalgia" patented technology

A pharmaceutical composition comprising: (a) meloxicam or a pharmaceutically acceptable salt thereof; and (b) one or more additional pharmaceutically active compounds selected from antacids, sedatives, and central nervous system stimulants, and the use of such composition of an inflammatory disease, symptoms of an inflammatory disease, including various symptoms thereof, and/or headache, toothache, ache after tooth extraction, sore throat, otalgia, arthralgia, neuralgia, lumbago, myalgia, muscle stiffness of shoulder, pain of contusion, pain of fracture, pain of sprain, menstrual pain, traumatic pain, chill, exothermic reaction and/or cold and various symptoms of cold such as sore throat, chill, pyrexia, headache, arthralgia and muscle pain.

ABSTRACTA pharmaceutical composition comprises a combination of a selective or specific COX 2 inhibitor or a pharmaceutically acceptable salt or derivative thereof and an opiate or a pharmaceutically acceptable salt or derivative thereof, for example a combination of meloxicam and codeine, as active ingredients, and a pharmaceutically acceptable carrier. It may include a centrally-acting cyclo-oxygenase inhibitor such as paracetamol or its pharmaceutically acceptable salts or derivatives. The pharmaceutical compositions are used in methods of providing symptomatic relief or treatment of pain, in an algesic and/or hyperalgesic state, with or without fever, in particular that associated with inflammation such as that associated with trauma, osteoarthritis, rheumatoid arthritis, non-inflammatory myalgia or dysmenorrhoea

A medicine for resisting rheumatism and alleviating pain is made from the materials with the following weight portions: 50 to 55 portions of gentian root, 70 to 75 portions of hemlock parsley, 70 to 75 portions of peach kernel, 65 to 70 portions of safflower, 50 to 60 portions of liquorice, 45 to 50 portions of notopterygium root, 60 to 65 portions of myrrh, 70 to 75 portions of angelica, 70 to 75 portions of boninrousette, 45 to 50 portions of nutgrass galingale rhizome, 75 to 80 portions of achyranthes root, 65 to 70 portions of earthworm, 65 to 70 portions of rhizoma atractylodis, 55 to 60 portions of corktree bark, 60 to 70 portions of milk veteh, 60 to 65 portions of salvia miltiorrhiza, 60 to 65 portions of spatholobus stem, 60 to 65 portions of pawpaw, 55 to 65 portions of paniculater swallowwort root, 60 to 65 portions of pachyma cocos, 55 to 60 portions of ground beetle, 40 to 45 portions of natural copper and 35 to 40 portions of dragon blood. The medicine can cure rheumatoid arthritis, hyperosteogeny, sciatica, cervical spondylosis, periarthritis, various arthralgia, neuralgia, kidney deficiency, lumbocrural pain, myalgia, exercise injury pain and lumbar disc protrusion, which is effective in treatment.

The present invention relates to compounds having the general formula

or a pharmaceutically acceptable salt thereof, wherein R¹ is a saturated or unsaturated 5-, 6- or 7-membered, ring containing 0, 1, 2 or 3 atoms selected from N, O and S, wherein the ring may be fused with a benzo group, and is substituted by 0, 1 or 2 oxo groups, and wherein R¹ is additionally substituted; and R² is a substituted C_1-6alkyl. Also included is a method of prophylaxis or treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

A Chinese medicine 'Rheumatalgia-relieving and pain-alleviating plaster of musk' for treating arthrodynia, myalgia, and sprain is prepared from 7 raw medicines. Its preparing process is also disclosed.

The invention discloses a medicine compound for curing rheumatism rheumatoid arthritis and a preparation method thereof. The medicine compound contains more than 50 kinds of traditional Chinese medicine, such as radix angelicae tuhuo, ramulus mori, Gentiana macrophylla, asarum, Clematis chinensis, Caulis Trachelospermi, wild aconite root, radix aconiti lateralis preparata, earthworm, attacus altisima, scorpion, and the like. The medicine compound of the invention is mainly used for thrombolysis, depressurization, relieving rheumatic pains, nourishing vitality and relaxing vein, relaxing the muscles, stimulating the blood circulation, and adjusting the immunity of human body. The medicine compound has unique effect in curing anemofrigid-damp arthralgia, arthralgia and myalgia, deficiency of the kidney, female blood-insufficiency, hemiplegia, lumbar vertebra and cervical vertebra. Besides the medicine compound has the effect of recovering the nerve function which the other medicines cannot reach. The medicine compound of the invention has obvious effect on curing rheumatism rheumatoid arthritis and paralysis caused by rheumatism, is free from toxic side effect, takes effect quickly and is convenient to use without boiling.

The present invention discloses an asarum tetraphylla medicine for external application for effectively curing the diseases of traumatic injuries, rheumatic arthrilis, rheumatic arthralgia and myalgia and soft tissue injury, etc. It is made up by using the Chinese medicinal materials of asarum tetraphylla, lycopodium cernuum, centipeda minima, ceratostigma minus, stahlianthus involucratus, justicia leptostachya and ethyl alcohol through a certain preparation process.

The invention provides a pharmaceutical for treating rheumatism and rheumatoid diseases. The pharmaceutical is prepared from glossy ganoderma, Chinese quince, notoginseng, safflower, eucommia bark, staghorn, angelica, cyathula root, licorice, glossy privet fruit, wild aconite root, processed monk shood, scorpion, uncaria stem with hooks, hairy birthwort, smilax, himalayan teasel root, cassia twig, dendrobium stem, Chinese ephedra, solomonseal, scurfy pea, Chinese ampelopsis, hawthorn, East Asian tree fern rhizome, long-noded pit viper, black-tail snake, Chinese polyphaga, Chinese honeylocust spine, muscardine silkworm, silkworm excrement, frankincense, myrrh, nux vomica, ledebouriella root, amomun fruit, Chinaroot Greenbrier Rhizome, weeping forsythia, giant mistletoe and coralbean bark. The pharmaceutical is effective in expelling wind dampness, relieving numbness and pain, nourishing the blood and promoting blood circulation and smoothing collaterals and nourishing yin, and is suitable for treating extremity numbness, arthralgia and myalgia, impotence of waist and knees, swelling, deformation and stiffness of joints, etc. caused by retention of arthralgia due to wind cold-dampness and arthralgia due to wind heat-dampness; and the pharmaceutical has reliable effect, less side effect and wide adaptive diseases.

The present invention discloses a Chinese medicine with the functions of promoting blood circulation, stopping pain, removing blood stasis, promoting the growth of new tissues and eliminating arthralgia and myalgia and preparation process of its adhesive plaster. It is made up by using 8 Chinese medicinal materials of notoginseng, dahurian angelica root, winglass cockroach, ligusticum root, Chinese angelica root, carthamus flower, borneol and camphor as main raw material and adding methyl salicylate, mentha camphor, belladonna liquid extract, chondroitin sulfate, diphenhydramine hydrochloride and dimethyl sulfoxide as auxiliary material through a certain preparation provess.

A pharmaceutical formulation of therapeutically effective amounts of acetaminophen, ibuprofen, and a sympathomimetic drug, such as pseudoephedrine (or its prodrug), or phenylephrine used in the treatment of cold and flu-like symptoms. Such symptoms may include fever, pain, nasal congestion, sinus congestion, runny nose, sore throat, myalgia, ear pressure and fullness, and headache. The formulation further includes various excipients used in the formulation process.

The present invention inter alia provides a method, and uses thereof, of predicting statin-induced muscle toxicity or its complications, such as myalgia, myopathy and rhabdomyolysis, by detecting the lipid concentrations or lipid-lipid concentration ratios of a biological sample and comparing them to a control. This method has identified lipid markers that are more specific and sensitive in detecting these statin-induced muscle toxicity than the currently utilized clinical markers. Also provided is an antibody towards said lipids, and the use thereof for predicting, diagnosing, statin-induced muscle toxicity. The invention additionally relates to kits comprising lipids and/or an antibody thereto, for use in the prediction and/or diagnosis of statin-induced muscle toxicity.

The invention discloses a traditional Chinese medicine for treating the muscle-bone pains and hand-foot insensibilities relates to a traditional Chinese medicine and solves the problems of unmarked treatment effect, low curing rate and easy recurrence existed in the present treatment of muscle-bone pains and hand-foot insensibilities. The Chinese medicine for treating the muscle-bone pains and hand-foot insensibilities of the invention has the weight portions of 2 to 6 portions of safflowers, 2 to 6 portions of wind-breakings and 2 to 6 portions of Chinese clematises. The invention has significant effects for muscle-bone pains, hand-foot insensibilities, rheumatoid arthralgia, cervical spine pains, scapulohumeral periarthritis, parenchyma wrenches, Traumatic Injury, muscle wrenches and sciatica. The invention is free of any poisonous substances and side effects; the invention is simple in ratio, low in cost, and good in efficacy and has the curing rate of 73.3 percent and the effective rate of 100 percent.

The present invention relates to compounds having the general formula

or a pharmaceutically acceptable salt thereof. Also included is a method of prophylaxis or treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

The invention discloses a medicinal plaster for removing stasis, eliminating stagnation and relieving swelling. The effective component of the medicinal plaster is prepared from the following raw materials in parts by weight: 10 to 40 parts of garden balsam stem, 10 to 40 parts of monkshood, 5 to 30 parts of kusnezoff monkshood root, 5 to 20 parts of Chinese angelica, 2 to 15 parts of camphor, 10 to 30 parts of rhubarb, 30 to 60 parts of elderberry, 10 to 20 parts of asarum, 5 to 25 parts of hemlock parsley, 5 to 30 parts of pawpaw, 10 to 30 parts of sappan wood, 2 to 15 parts of safflower, 5 to 25 parts of slenderstyle acanthopanax bark, 10 to 30 parts of drynaria rhizome, 10 to 30 parts of eupolyphaga, 5 to 20 parts of frankincense, 20 to 40 parts of myrrh, 5 to 20 parts of borneol, and 10 to 40 parts of dragon's blood. The medicinal plaster has excellent functions of activating blood circulation to remove stasis, dispelling wind and eliminating dampness, diminishing inflammation and removing swelling, softening and eliminating stagnation, and clearing and activating the channels and collaterals, helps a patient relieve pains, and can be used for treating lumbar spondylosis, cervical spondylosis, hyperosteogeny, fasciitis, arthralgia and myalgia, osteoarthritis, arthromeningitis, scapulohumeral periarthritis, mastitis, carcinoma part, nodule swelling, trauma and gout. According 1200 cases in nearly 3 years, the cure rate or effective rate of the medicinal plaster is 98 percent.

The snake and tortoise wine with enriched trace elements includes spirit, effective snake component, Chinese medicine components with tortoise component, honey product and enriched trace elements. The production process of the snake and tortoise wine with enriched trace elements includes the following steps: soaking killed snake with internal organs eliminated inside alcohol, soaking crushed Chinese medicinal materials inside alcohol, filtering the soaked liquids, mixing, adding honey product and trace element re-inforcer, and adding edible alcohol solution. The present invention has excellent health functions of dispelling wind and cold, warming spleen, treating numb hands and feet, treating arthralgia and myalgia, strengthening immunity, etc.

The present invention relates to compounds having the general formula

or a pharmaceutically acceptable salt thereof, wherein R¹ is a saturated or unsaturated 5-, 6- or 7-membered, ring containing 0, 1, 2 or 3 atoms selected from N, 0 and S, wherein the ring may be fused with a benzo group, and is substituted by 0, 1 or 2 oxo groups, and wherein R¹ is additionally substituted; and R² is a substituted C_1-6alkyl. Also included is a method of prophylaxis or treatment of inflammation, rheumatoid arthritis, Pagets disease, osteoporosis, multiple myeloma, uveititis, acute or chronic myelogenous leukemia, pancreatic β cell destruction, osteoarthritis, rheumatoid spondylitis, gouty arthritis, inflammatory bowel disease, adult respiratory distress syndrome (ARDS), psoriasis, Crohn's disease, allergic rhinitis, ulcerative colitis, anaphylaxis, contact dermatitis, asthma, muscle degeneration, cachexia, Reiter's syndrome, type I diabetes, type II diabetes, bone resorption diseases, graft vs. host reaction, Alzheimer's disease, stroke, myocardial infarction, ischemia reperfusion injury, atherosclerosis, brain trauma, multiple sclerosis, cerebral malaria, sepsis, septic shock, toxic shock syndrome, fever, myalgias due to HIV-1, HIV-2, HIV-3, cytomegalovirus (CMV), influenza, adenovirus, the herpes viruses or herpes zoster infection in a mammal comprising administering an effective amount a compound as described above.

The invention discloses externally-used medical liquor for clearing and activating channels and collaterals. The externally-used medical liquor for clearing and activating the channels and the collaterals is characterized by being prepared from the following medicinal materials: rhubarb, turmeric, pepper, kuh-seng and the like, in weight proportion through ethanol soaking. By the adoption of the externally-used medical liquor for clearing and activating the channels and the collaterals, disclosed by the invention, the total effective rate is up to 99%, and the cure rate is up to 92%; and the externally-used medical liquor for clearing and activating the channels and the collaterals, disclosed by the invention, is suitable for various illnesses such as traumatic injuries, sprains, arthralgia and myalgia, rash, pruritus, beriberi, bee sting and mosquitoes bite, the treatment cost is less than 40% of that of a common therapy, has a short treatment course, is easy for a patient to accept, and is simple in operation and convenient for nursing.

The invention aims to provide a cataplasm far-infrared medical application for treating arthralgia, myalgia, wind cold and numbness, which is elaborately developed by adopting rare pure traditional Chinese medicinal materials, a scientific novel method and a novel process. The application takes a formula in portion by weight: 40 g of borneol, 20 g of frankincense, 20 g of myrrh, 10 g of safflower, 10 g of panax notoginseng, 20 g of pangolin, 60 g of garden balsam stem, 20 g of common clubmoss herb and 400 g of colophony. The main composition of the formula is the pangolin, namely pangolin scales which is salty in taste and slightly cold in property, mainly treats wind cold and limbs numbness, and has the efficacy of dehumidifying, dissolving turbidity, diminishing inflammation and removing pain. The medical application has chlorpheniramine maleate and methyl salicylate which are effective compositions of western medicine added in preparation process, and uses far-infrared powder and biological magnetic powder which are the latest scientific achievements. The application has the advantages of clear effective compositions, obvious efficacy, few side effects, stable preparation and strict quality standard, thereby meeting the requirements of modern Chinese medicine on safety, high efficiency, stability and controllability.

The invention discloses a making method of a Chinese chestnut and mushroom particle drink and belongs to the field of drink processing. The making method is characterized by including three processing technological processes of firstly, Chinese chestnut cleaning, baking, soaking and boiling, pulping, filtering and Chinese chestnut pulp forming; secondly, mushroom soak cleaning, pelleting, heat leaching, filtering, leaching liquor forming and mushroom particle forming; thirdly, Chinese chestnut pulp and mushroom particle mixing and blending, homogenizing, bottling, sterilizing, cooling and finished product forming. The making method has the advantages that the drink is fragrant and sweet in juice, mushroom particles are moderate in size, the taste is fine and smooth, the faint scent of mushrooms and the fragrant and sweet flavor of the Chinese chestnuts are achieved, the sweetness is proper, the human immunity can be easily improved, the special curative effect is achieved for preventing osteoporosis and arthralgia and myalgia, the effects of delaying senescence, prolonging life, reducing blood pressure and blood fat and preventing and resisting cancer are achieved, and the drink is a green drink which is delicious, healthy, natural and pure; operation is easy, and implementation is easy.

The invention discloses a pharmaceutical composition for treating arthralgia and myalgia and belongs to the technical field of medicines. The pharmaceutical composition is prepared from 10-14 parts of rhizome and root of incised notopterygium, 10-15 parts of root of doubleteeth pubescent angelica, 8-12 parts of rhizome of chuanxiong, 8-12 parts of root of notoginseng, 3-7 parts of safflower flower, 3-7 parts of root of twotooth achyranthes, 3-7 parts of myrrh, 3-8 parts of olibanum, 6-10 parts of rhizome of tall gastrodia, 6-10 parts of root of Himalayan teasel, 3-8 parts of hairy antler and 13-18 parts of eucommia bark. The components of the pharmaceutical composition, which are common traditional Chinese medicine herbs, are simple relatively. The pharmaceutical composition, which is prepared as an external preparation, is safe and reliable, with the effective rate up to 100% and curative rate up to 85% to treatment of arthralgia and myalgia caused by various strains. In addition, the pharmaceutical composition is used for treating arthralgia and myalgia caused by various wind-cold-dampness arthralgia, with the effective rate up to 100% and the curative rate up to 86%, and has the advantages of quick action and obvious curative effect with the recurrence rate less than 10%.

The present invention discloses a trachelospermum divaricatum Huoluo Shangshi Zhitong plaster for effectively curing the diseases of traumatic injury, soft tissue contusion, rheumatic arthritis, rheumatoid arthritis, rheumatic arthralgia and myalgia, etc. with obvious therapeutic effect. It is made up by using 8 Chinese medicinal materials of trachelospermum divaricatum, chamaerhodos erecta, millettia reticulate, ardisia gigantifolia, neocinnamomum caudatum and others and adding rapeseed oil through a certain preparation process.

The invention discloses a manufacturing method for a chestnut paste healthcare cake, and belongs to the field of food processing. The manufacturing method is characterized in that raw materials of 15 kg of high gluten flour, 3 kg of potato starch, 8 kg of butter, 350 g of egg white, 35 kg of chestnut kernels, 2.5 kg of maltose, 16 kg of saccharose, 2 kg of lard stearin and 3 kg of plum blossoms are adopted, and the processing technology of the chestnut paste healthcare cake includes the steps of raw material processing, pulp grinding, stuffing manufacturing, dough kneading, crisp manufacturing, stuffing wrapping, baking, packaging and finished product forming. The manufacturing method has the advantages that the product is slightly yellow in color, crispy, tasty, fine and smooth in taste and rich in aroma and has the crispy flavor of chestnuts. The product is delicious, tasty, rich in nutrition and beneficial to improving the immunity of the human body, has the special curative effects on preventing osteoporosis, arthralgia and myalgia and has the effects of delaying senescence, prolonging life and preventing cancers. The chestnut paste healthcare cake is convenient to eat and simple in operation and is green food which is delicious, tasty and rich in nutrition.

The invention provides a medicine for treating rheumatism and rheumatoid diseases. The medicine is prepared from the following Chinese herbal medicines in part by weight: 9 parts of lucid ganoderma, 7 parts of papaya, 7 parts of notoginseng root, 7 parts of safflower, 12 parts of eucommia bark, 18 parts of common clubmoss herb, 8 parts of Chinese angelica, 11 parts of medicinal cyathula root, 6 parts of liquoric root, 3.5 parts of prepared kusnezoff monkshood root, 4.5 parts of prepared common monkshood mother root, 4.2 parts of scorpion, 12.5 parts of gambir plant, 8 parts of himalayan teasel root, 6 parts of cassia twig, 9 parts of dendrobium, 7.5 parts of ephedra herb, 14 parts of siberian solomonseal rhizome, 7 parts of malaytea scurfpea fruit, 7 parts of east asian tree fern rhizome, 4 parts of little multibanded krait, 6 parts of garter snake, 6 parts of Chinese honeylocust spine, 6 parts of stiff silkworm, 5 parts of frankincense, 5 parts of myrrh, 0.5 part of prepared nux vomica, 8 parts of divaricate saposhnikovia root, 8 parts of tuckahoe and 25 parts of medlar. The medicine has the effects of expelling wind-damp, relieving pain or numbness, nourishing blood, promoting blood circulation, dredging collaterals and nourishing yin, and is suitable for treating symptoms of deadlimb, arthralgia and myalgia, waist-leg weakness, arthrocele, dysarthrosis, sluggish flexion and extension of joints and the like which are caused by anemofrigid-damp arthralgia and rheumatic pyretic arthralgia retention.

The invention discloses a plaster for treating arthralgia and myalgia, which is prepared from notoginseng, orientvine, 40-50g of rhaphidophora decursiva, girald daphne bark, rubus multibracteatus, overall angelica, zedoary, stephania tetrandra, gentiana macrophylla, clematis root, chaenomeles speciosa, notopterygium root, radix angelicae pubescentis, erythrina bark, wooly datchmanspipe herb, american lopseed, drynaria, chuanxiong rhizome, mastic, roasted myrrh, notoginseng, pangolin, draconis sanguis, scorpion, menthol, rosin, bee wax and clove oil. The plaster has the functions of expelling pathogenic wind, eliminating dampness, dispelling cold, promoting blood circulation, activating meridians, relieving pain, eliminating swelling, dissipating blood stasis and strengthening muscles and bones. The plaster has a good effect on treating acute and chronic soft tissue injury, cervical spondylosis, scapulohumeral periarthritis, lumbar intervertebral disc protrusion and knee-joint pain.

The invention discloses a medicinal composition for treating rheumatism and rheumatoid disease. The medicinal composition comprises black ant, processed radix aconiti, processed radix aconiti kusnezoffii, frankincense, epimedium herb, cassia twig, mulberry, Ningpo yam rhizome and the like. The medicinal composition has the effects of relaxing muscles and stimulating blood circulation and expelling wind and removing dampness, is used for anemofrigid-damp arthralgia, acroanesthesia, fasciitis, arthralgia, myalgia and difficult walking, has remarkable curative effect on diseases such as rheumatism, rheumatoid arthritis, cervical vertebra, lumbar vertebra and scapulohumeral periarthritis, waist and leg pain, arthroncus, acroanesthesia, joint sprain, traumatic injury, lumbar muscle strain, hyperosteogeny, spur, heel spur, postpartum rheumatism and the like, and has no toxic or side effect.