1556 results about "Lipid lowering" patented technology

The invention discloses pressure lowering and lipid lowering sweet corn soup and a preparation method thereof. The pressure lowering and lipid lowering sweet corn soup consists of the following raw materials in parts by weight: 40-50 parts of corn, 10-15 parts of oat, 5-10 parts of leek, 5-10 parts of pawpaw, 5-8 parts of cucumber, 4-6 parts of celery, 5-8 parts of chicken meal, 3-5 parts of coix seed, 3-4 parts of tangerine peel, 2-4 parts of mulberry leaf, 1-3 parts of cochinchinese asparagus root, 2-3 parts of ginkgo leaf, 1-3 parts of gynostemma pentaphyllum, 2-4 parts of medlar, 1-3 parts of egg, 2-3 parts of lactic acid bacteria tablet, 5-6 parts of grape juice and 5-7 parts of nutritional additive. The pressure lowering and lipid lowering sweet corn soup prepared by the invention is convenient to store, carry and eat, can be eaten after a can is opened, contains various nutrient substances, is rich in nutrition, has good mouthfeel, can also lower the lipid and can be eaten by various kinds of people; the formula contains natural plant compositions such as the tangerine peel, the mulberry leaf, the cochinchinese asparagus root and ginkgo leaf; the sweet corn soup has the effects of lowering lipid, lowering pressure, tonifying lung, strengthening spleen, protecting liver and nourishing kidney, can be eaten for a long time, can nourish the five internal organs, improves the immunity and has a health care effect of strengthening the body.

The invention belongs to the technical field of affinal drug and diet formulas and new resource food, and particularly provides blood fat-reducing medical science formula food, specific medical formula food or non-specific medical formula food. The formula food is prepared by performing reasonable compatibility on multiple affinal drug and diet traditional Chinese medicines according to the traditional Chinese medicine essence theory and mixing drug-diet dual purpose traditional Chinese medicine extract essence extracted through a semi-bionic extraction method, multiple microencapsulated probiotics, oligopeptides extracted through biological enzymolysis, prebiotics, amino acid, carbohydrate, fat with a health-care function, multiple vitamins and mineral substances according to the requirements of a 'special medial-purpose formula food general rule' by combining the constitutive characters of hyperlipidemia patients; the formula food not only can serve as a single nutrition source to meet the nutritional requirement of the hyperlipidemia patients, but also achieves the effects of reducing total cholesterol, reducing serum triglyceride, reducing an atherosclerosis index, reducing blood pressure, reducing blood sugar, reducing fat to lose weight and enhancing the immunity.

PCT No. PCT/JP96/02596 Sec. 371 Date Mar. 12, 1998 Sec. 102(e) Date Mar. 12, 1998 PCT Filed Sep. 12, 1996 PCT Pub. No. WO97/10224 PCT Pub. Date Mar. 20, 1997This invention provides new benzoxazepine compounds represented by the formula: [wherein R stands for a lower alkyl group optionally substituted with a hydroxyl group, X stands for an optionally substituted carbamoyl group or an optionally substituted heterocyclic group having a deprotonatable hydrogen atom, R1 stands for a lower alkyl group and W stands for a halogen atom] having activities of lowering chlesterol-level and lowering trigluceride-level, and being useful for prophylaxis and therapy of hyperlipidemia.

This invention provides compounds of formula I

and pharmaceutically acceptable salts and solvates thereof, characterized that the compound is in particulate form and having a specific size range.

The present invention further provides pharmaceutical compositions containing or formulated using compounds of formula I, and the use of such compounds for alleviating human pathologies, including osteoporosis, serum lipid lowering, and breast cancer.

The invention provides a cassia obtusifolia tea bag with functions of weight reduction, hypotension and hypoglycemic effect, which is characterized in that the production process comprises the following steps: washing, cleaning and drying the cassia obtusifolia stem, leaf and grain, crushing by a pulverizer to 280 meshes, uniformly stirring, packing, disinfecting to obtain the cassia obtusifolia tea bag with functions of lipid lowering, hypotension and hypoglycemic effect. The optimal composition and the weight part ratio of the tea bag are: 40-60 parts of dried cassia obtusifolia stem, leaf and grain, 10 parts of dried lotus leaf, 5 parts of haw, 5 parts of dried balsam pear, 5 parts of Chinese wolfberry, 10 parts of Pu'er tea, 10 parts of cassia seed, 5 parts of mulberry leaf, 5 parts of folium apocyni veneti, 5 parts of Chinese yam as medicine, 3 parts of rhubarb, 2 parts of chrysanthemum, 2 parts of honeysuckle flower, 1 part of boat-fruited sterculia, 5 parts of cassia seed, 5 parts of kudzu root and 10 parts of additive. The additive is composed of fatty acid sucrose ester, xylitol, mannitol crystal, natural menthol, citric acid, trisodium phosphate, sodium saccharin and steviosid; the above components are carried out the processes of crushing, mixing, uniformly stirring, packing and disinfecting to obtain the tea bag.

A composition which includes a salt of metformin and the use of the composition for treatment of or use in prediabetes, diabetes, lowering triglycerides and/or other conditions in mammals.

The invention relates to blood lipid-lowering active fractions of forsythia suspensa and a preparation method and use of the same. The active fractions are ethyl acetate fractions obtained by concentrating an extract which is extracted from forsythia suspensa leaves by acetone and water. The compound of phillygenin prepared by the invention and the active fractions, namely the ethyl acetate fractions, at which the phillygenin is positioned have good antioxidant activity in vitro. In-vivo experiments show that the ethyl acetate fractions and the phillygenin can lower total cholesterols and low-density lipoprotein cholesterin in the blood serum of a mouse with hyperlipidemia and can lower blood lipid level by an oxidative approach (raising superoxide dismutase SOD and lowering malonydialdehyde MDA). In addition, the ethyl acetate fractions have a better effect of reducing the total cholesterols in the blood serum of the mouse than the phillygenin and cassia seed blood lipid-lowering tablets. The ethyl acetate fractions of the forsythia suspensa leaves can be further developed to play a role in the multi- target co-prevention and treatment of hyperlipidemia and other diseases and have a good application prospect.

The invention discloses a lipid-lowering ginkgo seed tea, being prepared from the following raw materials: hawthorn fruit, cassia seed, giant knotweed rhizome, fleeceflower root, lucid ganoderma, rhubarb, root of lobed kudzuvine, malt dextrin, flavonoids of ginkgo seed, polyphenols, stevioside, vitamins, thickeners, co-solvents, dispersants, antioxidants, flavor enhancers, and flavoring agents. The lipid-lowering ginkgo seed tea is prepared from the steps of liquid extraction, clear paste preparation, granulation, sterilization and the like. The ginkgo seed tea provided by the invention has a lipid-lowering effect, a blood nourishing effect, and high lipid-lowering effectiveness, and a prepared drink tastes good and mellow. The ginkgo seed tea provided by the invention contains an essence extracted from pure natural plants without adding any preservatives and pigments, breaks through the cold tea technology, and utilizes the low-temperature extraction technology to ensure that the active ingredients in the plants are not destroyed, and the tea is easily absorbed by the body after being drunk, and the shortcomings of traditional products are overcome by easiness in dissolution and absorption.

The invention discloses a natural medicament with the functions of hyperglycemic and lipid lowering as well as weight losing. The medicament is a resveratrol compound pigeon bean acid ketone A which can be prepared into a medicament preparation for curing diabetes or adiposity, and can also be prepared into a health-care food which is beneficial to a diabetes suffer or an adiposity suffer. The invention simultaneously discloses a compound of a plant source containing the pigeon bean acid ketone A as well as the use of the medicament and the health-care food thereof used for curing the diabetes.

The invention discloses liquid-lowering health cookie. The liquid-lowering health cookie is made with, by weigh, 100-110 parts of flour, 40-50 parts of natto, 20-30 parts of mung bean powder, 1-2 parts of lotus leaf, 1-3 parts of Kuding, 2-3 parts of pubescent holly root, 1-2 parts of suberect spatholobus stem, 15-20 parts of broccoli, 10-14 parts of bamboo shoot, 8-12 parts of Chinese Mesona herb, 12-15 parts of wax apple, 20-30 parts of codfish, 5-8 parts of salt, 1-2 parts of cookie additive, and the proper amount of water. The natto added to the liquid-lowering health cookie is rich in protein, cellulose, calcium, iron and the like, and has the effects of thrombolysis, tumor suppression, blood pressure lowering, blood lipid lowering, oxidation resistance, osteoporosis prevention, blood clotting promotion and the like. The wax apple is a fine fruit for treating various diseases, has sweet taste and neutral nature, and has the effects of moistening lung, suppressing cough, eliminating phlegm, cooling blood, and astringing. The Chinese Mesona herb has the effects of clearing summer heat and cooling to excrete water, and has good therapeutic effect on hypertension, kidney diseases, diabetes, joint muscular pain and the like. The Kuding has the effects of clearing summer heat, improving eyesight and promoting intelligence, helping produce saliva and slake thirst, lowering blood lipid, preventing cancer and senescence, invigorating blood vessels and the like.

The invention relates to field of natural medicine and medicinal chemistry, in particular to novel pentacyclic triterpene and melbine salt I of the derivative thereof. The salt compound can be used for preparing medicaments curing diabetes mellitus and complicating disease thereof, cerebral ischemia, angiocardiopathy, atherosclerosis, hepatitis, fatty liver and metabolic syndrome or tumour, descendens blood fat drugs and anti-obesity drugs. The invention also relates to the preparation method of the salt compound.

The invention provides a lipid-lowering and weight-reducing nutritional meal powder and a preparation method thereof. The lipid-lowering and weight-reducing nutritional meal powder comprises the following materials in part by weight: 5-20 parts of konjaku flour, 5-20 parts of resistant dextrin, 1-5 parts of l-carnitine, 5-20 parts of oats dietary fiber bran, 10-20 parts of soybean protein isolate powder, 10-20 parts of whey protein concentrate, 1-10 parts of hericium erinaceus polysaccharide, 1-10 parts of lentinan and 1-5 parts of casein glycomacropeptide. The hericium erinaceus polysaccharide and the lentinan are respectively extracted from hericium erinaceus and mushroom. The preparation method mainly comprises the following steps of (1) extracting the hericium erinaceus polysaccharide and the lentinan; (2) mixing the hericium erinaceus polysaccharide and the lentinan; (3) performing granulation; and (4) performing sterilization and bagging. Substances with special effects are compounded, nutrition intake of human bodies is improved and the digestive health is guaranteed while the purpose of lowering lipid and reducing weight is achieved, shortcomings of weight-reducing products in markets are overcome, and scientific weight reduction is realized further.

The invention discloses a lipid-lowering weight-losing lotus leaf beverage and a preparation method thereof. The beverage is prepared from lotus leaves, hawthorn, and cassia seeds. The lotus leaf beverage disclosed in the invention has significant effect on lowering lipid and losing weight, has no toxic or side effects, and is suitable for drinking by vast obesity populations and patients with hyperlipemia.

The present invention provides unique, efficacious, inexpensive, safe, reliable, convenient, minimally bitter, skin protecting and penetrating, easy-to-administer base compositions and active agent-containing compositions, such as those including hydrocortisone, and related production and topical application methods, for treating the skin of mammals for a wide variety of different dermatologic conditions, disorders and diseases, such as inflammation, redness, cracking, insect bites, dryness, allergic reactions, trauma, irritant dermatitis, perleche, contact dermatitis, psoriasis, eczema, seborrheic dermatitis, acne excoriate, xerosis, eczema craquele, stasis dermatitis, disease related conditions and dryness from medications such as isotretinoin, acitretin and lipid lowering agents. This is effected by topically administering, or otherwise applying, effective amounts of the compositions thereto in forms that not only address the skin and mucosa of the mouth and lips, but also of the rest of the body and, in particular, areas where other topical balms containing hydrocortisone and other active ingredients have not been developed or marketed. Additionally, the flavoring addition to this product, and the base wherein the active ingredient(s) reside, affords a significantly better tasting, and less bitter, composition, thereby allowing a more pleasant experience and better compliance by patients. Larger sized stick formulation(s) allow for more applicability of the product, and more usefulness thereof, in various areas, and mucosal skin, of the body. The compositions include a unique formulation of FANCOL VB, Natunola Castor 1023, Finsolv TN, bees wax and, optionally, one or a plurality of plant or plant seed oils, fatty alcohols, fats and flavorings, in desirable weight percents thereof, in various forms, and preferably in the form of a solid roll-on stick present in a variety of sizes.

The invention relates to a cyclocarya paliurus tea beverage. In parts by weight, 100 parts of a cyclocarya paliurus tea beverage comprises 10 to 30 parts of cyclocarya paliurus leaves, 5 to 20 parts of green tea, 5 to 10 parts of hawthorn, 1 to 5 parts of a sweetening agent and the balance being water. A preparation method of the cyclocarya paliurus tea beverage comprises the steps of selecting materials, extracting, filtering, mixing, filling, sealing, sterilizing and cooling. Compared with pure green tea, the cyclocarya paliurus tea beverage has an extra function of reducing the high blood fat, the high blood pressure and the high blood sugar and also has certain healthcare functions; compared with pure cyclocarya paliurus tea, the cyclocarya paliurus tea beverage has a more remarkable lipid lowering effect. Compared with a conventional water extracting method, an ultrasonic multilevel countercurrent contact water extracting method adopted by the method has the advantages that the extracting rate of active ingredients can be increased by 20 to 30 percent, and certain economic benefits can be brought to enterprises. The requirement on equipment is low, the cost is low, the operability is high, the energy consumption is small, and the industrialized mass production of cyclocarya paliurus tea beverages can be realized.

The invention discloses a health-care clam seasoning powder and a preparation method thereof. The health-care clam seasoning powder is prepared through complex formulation of the following components by weight: 60 to 75% of a clam extract, 3 to 8% of monosodium glutamate, 10 to 18% of refined salt, 4 to 10% of a sweetener, 0.2 to 1% of a traditional Chinese medicine powder, 0.5 to 1% of powdered cinnamon, 0.1 to 0.5% of fennel powder, 0.2 to 0.8% of powdered pepper, 0.1 to 0.3% of sodium succinate and 0.1 to 0.5% of an anti-oxidant. The preparation method comprises the following steps: preparation of the clam extract; preparation of the traditional Chinese medicine powder; complex formulation; etc. According to the invention, meat of clam is subjected to enzymatic hydrolysis, concentration and spray drying to prepare powdered clam which is rich in bioactive peptide, a variety of amino acids, vitamins and trace elements and has the characteristics of clearing of lung-heat, reduction of phlegm, abundant nutrients and fast absorption by a human body; moreover, the traditional Chinese medicine powder having the health-care effects of reducing blood sugar and lowering lipid is added; the content of each component is reasonably compatible; production cost is low; the produced clam seasoning powder has excellent taste and quality; and the preparation method is simple, enables a long shelf-life of the clam seasoning powder to be obtained and is beneficial for popularization.

The present invention provides novel N-benzyldioxothiazolidylbenzamide derivatives that improve the insulin resistance and have potent hypoglycemic and lipid-lowering effects and processes for preparing the same, and relates to N-benzyldioxothiazolidylbenzamide derivatives characterized by being represented by a general formula (1) [wherein R1 and R2 denote identically or differently hydrogen atoms, lower alkyl groups with carbon atoms of 1 to 4, lower alkoxy groups with carbon atoms of 1 to 3, lower haloalkyl groups with carbon atoms of 1 to 3, lower haloalkoxy groups with carbon atoms of 1 to 3, halogen atoms, hydroxyl groups, nitro groups, amino groups which may be substituted with lower alkyl group(s) with carbon atoms of 1 to 3 or hetero rings, or R1 and R2 link to form a methylenedioxy group, R3 denotes a lower alkoxy group with carbon atoms of 1 to 3, hydroxyl group or halogen atom, and dotted line indicates double bond or single bond in combination with solid line], and processes for preparing the same.

Statin therapy has revolutionized the treatment of cardiovascular disease, but not all patients can take the appropriate level of statins because of their side effects. The present invention provides compositions that provide potent cholesterol lowering while minimizing the damaging side effects to liver, muscles, and neurons, and has the added benefit of reducing chronic systemic inflammation, which is an independent determinant of cardiovascular disease and all-cause mortality. The current invention presents pharmaceutical compositions for reducing cholesterol and chronic systemic inflammation comprising therapeutically effective amounts of: at least one lipid-lowering agent chosen from HMG-CoA reductase inhibitors, high-dose controlled-release niacin, red yeast rice, or policosanol; and at least one antiinflammatory natural product chosen from alpha-lipoic acid and corosolic acid. To those in need of such treatment, the current invention also provides safe methods for reducing high serum cholesterol or chronic inflammation, or for simultaneously reducing both cholesterol and chronic inflammation via treatment with therapeutically effective daily doses of pharmaceutical compositions as described herein. The present invention provides mammals with compositions and methods for concurrently reducing cholesterol and inflammation as a prevention or treatment for many age-related diseases and disorders.

The invention discloses a medicine combination of adjusting hypertension, hyperlipidemia and angina, consisting of astragalus, panax, salvia, cynostemma, americanwater plantain, ginkgo biloba, panax notoginseng, hawthorn, mythic fungus, schisandra, fragrant solomonseal rhizome and wolfberry fruit. The medicine combination of the invention has the advantages of invigorating qi and replenishing yin, activating blood and stabilizing pain, nourishing heart and calming mind, replenishing qi and nourishing blood, supplementing spleen and invigorating kidney, promoting moisture and urination, clearing heat, detoxifying and cooling blood, reducing tension, clearing liver, reducing lipid, nourishing yin, improving eyesight, reinforcing kidney, reducing sugar, dual directionally regulating and etc. Meanwhile, the medicine has an obvious effect on treating hypertension, hyperlipidemia, angina, and the hypertensions and anginas caused by unknown reasons.

The invention provides a radix codonopsis-chrysanthemum lipid-lowering health-care rice cake. The rice cake is prepared from the following components by weight: 80 to 90 parts of glutinous rice, 10 to 12 parts of yellow millet, 10 to 15 parts of soya bean, 8 to 10 parts of asparagus pea, 4 to 6 parts of black sesame, 2 to 3 parts of a mulberry leaf, 3 to 4 parts of a ginseng leaf, 2 to 4 parts of chrysanthemum, 3 to 5 parts of honeysuckle flower, 2 to 4 parts of a broad bean flower, 5 to 7 parts of broad-leaved epiphyllum, 2 to 3 parts of shaddock peel, 3 to 4 parts of radix codonopsis, 1 to 2 parts of a cowpea leaf, 2 to 3 parts of kelp base, 2 to 4 parts of safflower, 3 to 4 parts of cattail pollen, 2 to 3 parts of fleece-flower root and 0.01 to 0.02 part of camellia powder. The health-care rice cake provided by the invention has the characteristics of lung moistening, lipid reduction, digestion promotion, delicate fragrance, smooth taste and the like and is applicable to a variety of populations. The health-care rice cake overcomes the disadvantage that a traditional rice cake is stodgy, changes herbal medicine taste of traditional herbal health-care food and is particularly applicable to people with high blood pressure.

The invention relates to a traditional Chinese medicine for treating hyperlipidemia. The components of the medicine comprise ginseng, Radix Astragali, prepared rehmannia root, fleece-flower root, bighead atractylodes rhizome, rhizoma atractylodis, Poria cocos, Alisma Orientalis, Cortex moutan, radix paeoniae rubrathe, red sage root, rheum officinale, pseudo-ginseng, haw and cassia seed. The selection of medicine components and drugs dose is determined in dependence on the physique and condition of a patient, such as adding rehmanniae radix and ligustrum lucidum for patients of yin asthenia constitution and adding Aconite Root, and cassia twig for patients of yang-deficiency constitution, using decoction or pill. The traditional Chinese medicine treating hyperlipidemia in the invention has the efficacy of supplementing qi, nourishing yin, nourishing kidney, invigorating spleen, disinhibiting dampness, transforming turbidity (reducing phlegm), promoting blood circulation and removing blood stasis, and is suitable for treating hyperlipidemia. The medicine has the advantages of fast effect, no rebound after treatment, prevention of complications caused by hyperlipidemia and no side-effect.

The invention relates to lipid-lowering fat-reducing plant extract particles, which are made from the following components of: by weight, 60-75 parts of lotus leaf, 5-15 parts of root of kudzu vine, 5-15 parts of haw and 5-10 parts of cassia seed. The invention is characterized in that four natural plants as a homology of medicine and food are selected as raw materials; and the lipid-lowering fat-reducing plant extract particles have no side effect but have effects of adjusting blood fat and reducing fat.

The invention discloses a lipid-lowering healthcare duck crisp and a processing method of the lipid-lowering healthcare duck crisp. The method comprises the following steps: washing and dewatering the duck, performing vacuum massage by fried salt, then sealing and pickling, adding water together with a herbal cuisine seasoning bag for marinating, steaming at high pressure, stirring the materials, filling into a mold, shaping, and then packaging to obtain the finished product, wherein in processing ingredients of the duck, Chinese medicinal herbs are added besides ordinary spices, and a chemical preservative is replaced by lotus leaf powder. The lipid-lowering duck crisp processed by the method provided by the invention is characterized by golden color, palatable softness and hardness of tissues with just slagging in the mouth, deliciously sweet and salty taste, intense and pure fragrance with mouthful fragrance; besides, the lipid-lowering duck crisp has a lipid-lowering healthcare function; a novel leisure food which is convenient to eat is provided for patients having high blood lipid, and the variety of the duck used as the leisure food is enriched.

The invention discloses a lipid reduction tea and its production method; the tea is composed of glossy ganoderma, angelica, hemlock parsley, hawthorn, sea backthern, lotus leaf, dried orange peel, gynostemma pentaphylla, fleece-flower root, folium ginkgo, glossy privet fruit and cassia seed; the above-mentioned materials are disinfected, grinded, screened and packaged to get the product. The tea has functions of reducing cholesterin and triglyceride.